Kuyini disulfiramopodobnye yokusabela? Yiziphi esiyingozi?

Ngaphansi kwezimo ezivamile, lapho engena phakathi umzimba ngokushesha ubola ku utshwala metabolites (imikhiqizo umzimba akunabo ubuthi). Nokho, ngesisekelo yokwamukela izinhlobo eziningi zezidakamizwa avele ukushayisana inqubo ukuwohloka. Izinga yamakhemikhali. ngeke ukusabela zincike umthamo zomuthi kanye nenani utshwala. Emithini, ingqondo thuthuva, kufanele ichasiselwe ngokuyinhloko antibiotic. Ukusetshenziswa kotshwala ngesisekelo ukwelashwa zinemiphumela engathí sina. Lezi zihlanganisa disulfiramopodobnye ukuphendula. With ukuthuthukiswa miphumela ezigulini avele, kanye nezinye izimpawu, ukuya imikhiqizo utshwala ezisekelwe.

Ukwakhiwa ingqondo ukusabela disulfiramopodobnye

Kusho "Trykhopol" has elwa namagciwane kanye umsebenzi antiprotozoal. Lapho kuhlangene i nomuthi utshwala benza isimo esibi lesiguli lapho sibonakalise disulfiramopodobnye ukuphendula. Lezi izindawo ukuvumela ukusetshenziswa nomuthi wokwelapha yotshwala ezingamahlalakhona. Kaningi inikezwa izidakamizwa ezifana "Amoxicillin". Lo muthi kungabangela ukuphefumula nobunzima, kanye notshwala singavimbela umsebenzi zobuchopho isikhungo zokuphefumula. Kule ndaba, inhlanganisela izimali "Amoxicillin" kanye notshwala kwandisa amathuba yokufa kwabantu ngubani sebedakiwe. Kukhona imithi ukuthi wabelwe ngokuqondile kubangele disulfiramopodobnye ukuphendula. Lawa izidakamizwa njenge "Esperal", "Antabuse" nabanye. Ngezinye reception yabo ukubhujiswa enzyme ethile. Igama livela ukusabela izidakamizwa "Disulfiram". Lokhu imithi futhi, kanye nezinye izindlela ezifanayo, isetshenziswa ukwelapha utshwala ngokweqile kuzo ifomu ezingamahlalakhona. Isimo esiholela lapho reception ngokuthi disulfiram-utshwala, uma side effect kubangelwa neminye imithi - disulfiramopodobnyh.

Ngenxa yemiphumela emibi

Kutfutfukiswa isimo okubangelwa ekuqongeleleni emzimbeni komkhiqizo ngokuwa Ethanol - acetaldehyde. Le ngxube has ubuthi okusezingeni eliphezulu. Ngaphansi kwezimo ezivamile, izidakamizwa is neutralized ngaphansi isenzo esithile enzyme (noma ezinye aldehyde). Eminye imithi singavimbela umsebenzi kulezi zingxenye. Ngenxa yalokho, kukhona ukunqwabelana acetaldehyde emzimbeni, okuyinto kuhambisana eziningi izimpawu sici. Ngesikhathi imithi efanayo ukuvimba isenzo lomunye uchungechunge enzyme. Lokhu, kwenza abantu bakuphathe ukwehla kwamazinga noradrenaline e isimiso sezinzwa futhi ukuhlukumeza of ubuhlobo baso Dopamine. Ngenxa yalokho, disulfiramopodobnye ukusabela kuthiwa iyakhula nakakhulu. Ochwepheshe uqaphele ukuthi lesi simo has imvelo ngokwanele okuqhubekayo. Ngakho-ke, odokotela musa batusa ukuphuza utshwala emva kokuphothulwa sokuvivinya ubude esithile. Kufanele ukuthi imiphumela emibi yokusetshenziswa utshwala ngesikhatsi ukwelashwa zenzeka ngokushesha ngempela, ukwakha enyanya eqinile yotshwala.

Izimpawu disulfiramopodobnyh ukusabela

With ukuthuthukiswa side effects isiguli has a umuzwa imfudumalo ububomvu yomzimba engenhla futhi endaweni ebusweni. Ngaphezu kwalokho, ingcindezi encishisiwe, ukuphefumula nzima, kwenhliziyo. Iziguli zinamathuba umuzwa yobunzima esifubeni, ukwesaba. State kuhambisana nemicabango esongelwa ukufa, isicanucanu, retching. Ingozi ekhulile yemiphumela iziyaluyalu isimiso sezinzwa. Njengoba kwanda amanani utshwala kwandisa umfutho nobukhali disulfiramopodobnyh ukusabela. Kwezinye izimo, kungase ukuthuthukisa nciphisa - ukwehla elibukhali ingcindezi kanye nokulahlekelwa ukwazi.

Ukwelashwa kweziguli ukuluthwa utshwala okungamahlalakhona

Umlando ukusetshenziswa kwezidakamizwa "Disulfiram" ukuqeda ukuncika utshwala waqala nomunye mazwi athakazelisayo. Kwenye indawo okwakuvinjwe izimboni zokukhiqiza injoloba uye kakhulu ziyancipha ukusetshenziswa abasebenzi utshwala. Phakathi nesifundo, kwatholakala ukuthi imbangela kuyinto disulfiram into nje isetshenziswa ngesikhathi womshini izihloko zenjoloba. Ukuthola lokhu kwaholela yokuthi enkompolo waqala isetshenziselwe izinjongo zokwelapha. Ngemva nje kancane kwalokho, ochwepheshe waphawula ukuthi disulfiramopodobnye ukuphendula kuphakamisa inombolo yemithi. Ezinye zidakamizwa ngokuqondile uqoke yotshwala ezingamahlalakhona. Ngokwesibonelo, odokotela bavame linqume kusho "Trykhopol". Lesi sidakamizwa iyingxenye yokwelashwa eziyinkimbinkimbi abanye odokotela linqume namuhla. Kunconywa isiphuzo izifundo 250 mg 2 k. / Day. Ukwelashwa Kwenziwa kabili ngonyaka. Kwezinye izimo, imithi anqunyiwe kuze kudlule isikhathi eside - kufika ku ezinyangeni ezimbalwa.

Izixwayiso lapho imithi ethile

Ntu cha abaphethwe utshwala, odokotela batusa kakhulu ukuthatha noma yimuphi umuthi kuhlangene utshwala. Kubaluleke ngokukhethekile ukuba bagcine ukuqaphela lapho ethola ukwelashwa ngemithi elwa namagciwane. Kufanele kukhunjulwe ukuthi ukusetshenziswa ahlangene izidakamizwa futhi ethanol, ngaphezu ukuthuthukiswa ukusabela disulfiramopodobnyh, wandise nengozi yokuba isibindi oludakayo ukulimala, kwephulwe eziyinkimbinkimbi imisebenzi yalo ebaluleke kakhulu (filtration futhi ngokukhishwa kobuthi egazini). Ngaphezu kwalokho, kwandisa umfutho imiphumela emibi ukuthi avuse antibiotic, izidakamizwa ezithinta isimiso sezinzwa futhi amanye amalungiselelo. metabolites Toxic, okuyinto akhiwa inhlanganisela izidakamizwa notshwala, bayakwazi ukushintsha isinyathelo ezithathwe izimali. Lokhu-ke kuholela nemiphumela emibi kakhulu kwezinye izimo ezaholela ekufeni.

Okumele kuqashelwe yokwelapha, kuye ngokuthi kusetshenziswe utshwala

Kubantu ukuphila ngaphandle kotshwala, izidakamizwa ezahlukene athuthukile, kusiza balahle kulo mkhuba.

Ochwepheshe ukukhumbuza ukuthi imithi oyiphuzayo kufanele kuvunyelwane nodokotela wakho. Akubona bonke yotshwala ngokuzithandela uyavumelana ukwelashwa. Iziguli ezinjalo kufanele banikezwe usizo lokuqala ngokwengqondo. Umuntu ohlushwa ukusebenzisa uphuzo ngokweqile, kufanele baziswe ekwelapheni. Ngokuphazima umcimbi akufanele kube ngaphandle kolwazi lwakhe ukunikeza noma yimuphi izidakamizwa ezibangela ukuya utshwala! Lokhu "elapheke" ungakwazi nje kuphela babe ingaphumeleli, kodwa futhi zibe nemiphumela, kuyingozi futhi kwezinye izimo, imiphumela.