Izinhlobo kanye isinyathelo-insulini. ithebula

kwemithi Modern inikeza abanesifo sikashukela ibanga elikhulu insulin amalungiselelo. Futhi namhlanje sizobe ukukhuluma mayelana nokuthi yiziphi izinhlobo insulini ukuphi.

Insulin: Izinhlobo

Zonke insulini amalungiselelo etholakalayo zihlukaniswe ngezigaba ezintathu (kuye ngokuthi isenzo kanye nomphumela oqabulayo isikhathi):

• "Dlala";
• "Okulingene";
• "Long".

insulins "Dlala"

Kuyinto emfushane-esebenza insulini amalungiselelo zivame kakhulu ebekiwe iziguli ezinezinkinga kashukela.

Ngemva ejenti engena emzimbeni, uqala ukusebenza ngaphakathi imizuzu engamashumi amathathu. Lokhu uhumusha kube osenyameni ephumelelayo kakhulu izidakamizwa esetshenziswa ekwelashweni sikashukela. Kaningi, lolu hlobo insulini zinikwa insulini isenzo isikhathi eside.

Ukuze sithole choice, kufanele acabangele la maqiniso alandelayo:

• isimo Jikelele esigulini;
• Ukufakwa indawo kusho;
• umthamo.

Ethandwa kakhulu insulini amalungiselelo iqala ukwenza phakathi nezinsuku zokuqala imizuzu engu-15 ngemva kokuphathwa. Kusho "Apidra", "Humagol" futhi "Novorapid".

Izici

Phakathi ngesivinini womuntu insulini amalungiselelo ukunikeza "Homorap" futhi "Rapid Insumad". Umehluko phakathi kwazo nhlobo. Okuwukuphela umehluko - e lemali ezisalayo ekhona Ukwakheka yayo ama-amino acid.

Ngu insulins "okusheshayo" okuvela ezilwaneni nazo izidakamizwa "Insulrap SPP", "Iletin II avamile" nabanye. Basuke ngokuvamile ezinqunyiwe-type II sikashukela. Izimali ezivela kulesi sigaba zifaka ukubunjwa yayo amaprotheni ne isakhiwo ezahlukene, ngakho ayifanele okwazo zonke iziguli. Ngokwesibonelo, "fast" insulins okuvela ezilwaneni akufanele engabelwe kona abantu ngemizimba yazo ayikwazi kucutshungulwa isilwane lipids.

Reception, umthamo, isitoreji "amafushane" insulin

Ukuthatha izidakamizwa ngokushesha ngaphambi kokudla. Kulokhu, it ngesivinini ukugaya ukudla insulini umphumela kwenzeka ngaso leso sikhathi.

"Fast" insulini ingasatshenziswa ngomlomo, pre-ngibatshale ukuba isimo uketshezi.

Uma wayekwenza ekuphathweni ongama zomuthi, umjovo kufanele kwenziwe ngemizuzu engaba ngu-30 ngaphambi ukudla ehleliwe.

Umthamo umuntu ngamunye sikashukela, kukhethwe ngamunye. umthamo Adult kuyoba amayunithi 8-24 ngosuku, nezingane - akukho kuka amayunithi 8.

amalungiselelo ligcinwe ngaso + 2- + 8 degrees. Ngenxa yalesi eshalofini kufanelekile umnyango esiqandisini.

insulins "Isilinganiso"

Sikashukela kufanele baphuze imithi ukuthi ukusekela amazinga evamile kashukela. Kodwa uhlobo sikashukela ngayinye idinga ukuthi uhlobo oluthile nge-insulini. Kusukela izidakamizwa nokuba ubude obuphakathi, isetshenziswa esimweni lapho glucose idinga cleavage kancane kancane. Nokho lingasetshenziswa, uma okwamanje akunakwenzeka ukusebenzisa "amafushane" insulini.

Izici 'maphakathi' we-insulin

Izidakamizwa babe izici eziningana:

• kokuba ziqale ukusebenza ngokushesha nje kwemizuzu engu-10 ngemva kokuphathwa;
• kusho kuthatha Adalberto isikhathi eside ukuqeda lokubola.

Insulins yalolu hlobo ungaba isisekelo ezahlukene esebenzayo, ikakhulukazi, insulini isophane noma ukhethe. Ikakhulukazi kungase kutholakale kahle imithi ezilandelayo:

• phakathi insulini womuntu - kusho "Protafan", "Humulin", "Monotard" futhi "Homolong";
• phakathi imithombo isilwane - imithi "Berlinsulin", "Monotard HM" futhi "Iletin II".

insulins "Long"

Lokho isingeniso ngesikhathi esifanele izidakamizwa ivumela abanesifo sikashukela ukujabulela ukuphila ngaphandle kabi okubangelwa okusezingeni eliphezulu okuqukethwe ushukela egazini. Yini ehlukanisa lolu hlobo insulini amalungiselelo kusuka nezinye izilwane futhi babe insulini eside esebenza khona - le nkulumo.

Insulin umehluko oyinhloko kulokhu ukuthi umphumela izidakamizwa ngezinye izikhathi ukuthatha isikhathi eside kunokuba amahora angu-24.

Ngaphezu kwalokho, zonke izinhlobo insulini eside besebenza ngezithako zawo aqukethe yelikhono chemical ukuqinisekisa ukuthi ukusebenza yesikhathi eside zomuthi. Futhi alibale ukumuncwa ushukela. Umthelela zokwelapha kuyinto amahora mayelana 4-6 kanti isikhathi isinyathelo kungaba amahora afika kwangu-36.

Long-esebenza insulini: iziphi izinhlobo ezikhona

Imithi ngokuvamile esibekiwe simi "deterministic" futhi "glargine". The main umehluko - ngisho kashukela ongaphakeme.

Insulins nge isikhathi eside isinyathelo futhi amalungiselelo "Ultratard," "Ultralente iletin-1", "Huminsulin" "Ultralong" njll

imikhiqizo zemithi ebekwe udokotela ukuba khona, elibuye kusiza ukuba ugweme izinkinga ezihlukahlukene efomini amathuba okuba nemiphumela engemihle.

Sebenzisa futhi isitoreji izidakamizwa

Insulin lolu hlobo ingasatshenziswa kuphela ngomjovo. Kuphela kanye emzimbeni ukuze iqale ukusebenza. Kwabathinta wafaka ibhodi lemisindo, ethangeni noma buttock.

Ngaphambi ukusetshenziswa, isitsha kufanele ayonyakaziswa ukuze ubuyisele therein atholwe ukungaguquguquki iyunifomu. Ngemva kwalokho-ke ilungele ukusetshenziswa.

Ukwakheka kugcinwa ngaphansi kwezimo ezifanayo njengoba short-esebenza nge-insulini. isilawuli okunjalo lokushisa evimbela kumiswa ishq futhi pelletising ingxube, kanye izidakamizwa oxidized.

Jova nge-insulini wedwa, ngezinye izikhathi kabili emini.

Umsuka wegama insulini

Umehluko insulini - hhayi kuphela phakathi nesikhathi senzo, kodwa futhi imvelaphi. Ukwabela izidakamizwa isilwane futhi insulini nsé womuntu.

Ngokuba esigabeni sokuqala imikhiqizo esebenzisa kwamanyikwe ezingulube nezinkomo. Isakhiwo begazi insulini ikhiqizwa izitho ezingulubeni, efanelekayo abantu kakhulu. Umehluko kulokhu ngempela abangelutho - eyodwa kuphela-amino acid.

Kodwa izidakamizwa umhlabeleli Yiqiniso, insulins womuntu, ezisetshenziswa njalo kunazo. Esebenzisa ukukhiqizwa kungenzeka ngezindlela ezimbili:

1. Indlela yokuqala esikhundleni esisodwa acid okungalungile. Kulokhu, a insulini semisynthetic.
2. Ngo indlela yesibili bokukhiqiza izidakamizwa abathintekayo E. coli, ikhono synthesize amaprotheni. Lokhu kuzoba yindlela biosynthetic.

Ngokufana womuntu insulini amalungiselelo abe eziningi eziwusizo:

• ukukhiqiza wayefisa nomphumela oqabulayo kudinga esasikhipha ngemithamo ezincane;
• ukuthuthukiswa lipodystrophy kwenzeka kuqhathaniswa njalo;
• njengemithi yokungezwani komzimba nokuthile wezidakamizwa cishe ningagcini.

degree zokuhlanjululwa

Kuye ngezinga of nemikhiqizo yokuhlanza zihlukaniswe zibe:

• yendabuko;
• monopikovye;
• monocomponent.

insulins bendabuko phakathi insulini amalungiselelo yokuqala. Bona eziqukethwe ngezithako zawo ezihlukahlukene omkhulu wamaprotheni ezingcolisa, okuyinto eyaba imbangela njalo komzimba. Okwamanje, ukukhiqizwa amalungiselelo anjalo ziyancipha.

Kusho Monopikovye insulini abe esincane kakhulu ukungcola (ngaphakathi kwemingcele eyamukelekayo). Kodwa monocomponent insulins cishe ngokuphelele ihlanzekile, ngoba inani ukungcola okungafunwa, kancane ngisho kunomkhawulo aphansi.

umehluko enkulu "amafushane" futhi "eside" insulini

Njengoba ubona, izinhlobo insulini (Ithebula kukuveza obala loku) kuhluke izinkomba zokuveza indlela. Futhi lezi zici kudingeka kucatshangelwe.

Sesihlole zonke izinhlobo etholakalayo insulin nethonya lazo umzimba womuntu. Sithemba ukuthi ulwazi iye yaba usizo. Hlala uphilile!