Izici amathebhu isicelo "clomiphene citrate"

Ukulungiselela "clomiphene citrate" kuyinto setemlomo estrogen omelene, kungokwalabo iqembu ejenti non-steroidal. Ngenxa yalokho, ukusetshenziswa kwalesi izidakamizwa kakhulu kwandisa uketshezi we LH futhi FSH pituitary anterior ndlala kuvusa nokuvuthwa nokukhula alandelayo follicle. Ngenxa lo mphumela esimisiwe ejenti "clomiphene citrate" zivame ukwandisa ikhono wenzalo ezigulini zesifazane. Kulokhu, kubalulekile ngokuphelele kuvusa nge-ovulation, ngesikhathi esifanayo ivimbela isenzo estrogen emzimbeni. Ngaphezu kwalokho, kufanele kuphawulwe ukuthi lokhu ejenti ayinakho androgen noma gestagen umsebenzi, futhi ukuphuza amaphilisi amaningi, uyakwazi ezivimbela uketshezi of gonadotropins. Ngesikhathi esifanayo lo okuthiwa isigamu-ukuphila "clomiphene citrate" imayelana ezinhlanu izinsuku eziyisikhombisa.

Iyatholakala temlomo non-steroidal ejenti elikhona ngesimo ezivamile amaphilisi okwelapha nombala omhlophe. Ngoqobo ezifana clomiphene izenzo njengoba ingxenye main. Lokho-ke ngempumelelo kunciphisa ikhono steroid ukuhlanganisa uxhumano nomsebenzisi kwezinga receptor ezifanele.

Thatha iphilisi "clomiphene citrate" manual uncoma ekwelapheni anovulatory ukungazali kwabesifazane. Lesi sidakamizwa muhle kakhulu futhi enezinkinga ukopha lesizalo. Abesifazane abaphethwe yesibili, noma disgonadotropnoy postkontratseptivnoy amenorrhea, Kufanele futhi iqale ukuthatha leli thuluzi - isitha estrogen. Uhlu izimpawu eziyinhloko inhloso yazo, ngaphezu kwawo wonke la mazwi angenhla, futhi zihlanganisa amaqanda polycystic, androgen ukuntula futhi-Chiari syndrome Frommelya. Iziguli galactorrhea esungulwe, lakhula ngemuva kwe-isimila pituitary kuyinto iphilisi futhi kaningi okunqunyiwe "clomiphene citrate". Izibuyekezo uphawula umphumela omuhle reception zabo oligospermia. Ekugcineni, izidakamizwa ngenkuthalo esetshenziselwa sitholakele okuthiwa umsebenzi gonadotrophic ka neseleko cerebral - indlala pituitary.

Yabela kusho ngokuphelele akufanele kube esikhathini Endabeni yesiguli anda ukuzwela umuntu ukuba clomiphene, kanye esimweni lesizalo ukopha of omsakazo engaziwa. Ngaphezu kwalokho, kubalulekile ukuba ayeke ukuthatha imithi kubhekwe e hepatic ezinzima noma ukwehluleka kwezinso. Isimila noma isimila wesibeletho futhi kubangela ngokwehluleka e amaphilisi aphoyintimenti "clomiphene citrate". Babengakaze ukuthatha ngesikhathi sokukhulelwa.

Ekuphetheni, futhi phezu main side effects ukuthi kungase kubangelwe ngokuthatha ukulungiselela wathi. Ngokwesibonelo, abanye abesifazane bangase babe ikhanda, ukuqwasha, isiyezi, ukukhathazeka, ukucindezeleka nokukhathala. Ngaphezu kwalokho, kukhona ingozi ongaboni ka fibrosis ukukhulisa wesibeletho, ukuthuthukiswa pollakiuria, dysmenorrhea noma polyuria, futhi isisindo somzimba.