Inhibitor neuraminidase: uhlu izidakamizwa ukuze uthole imiyalo ukusetshenziswa

Uhlelo wezizwe izidakamizwa ngezigaba uhlukanisa zonke umsuka imikhiqizo kuqembu imithi. Isisekelo lesi isenzo kwemithi zezinto. Isihloko Kwethulwa uzokutshela mayelana eyodwa iqembu elinjalo. Siqukethe neuraminidase inhibitors. Uzothola ukuthi izithako ezisebenzayo kukhona isisekelo yabo, kanye bajwayelane amagama abo ukuhweba.

neuraminidase inhibitors

Ngaphambi sikhuluma izidakamizwa, kubalulekile ukuba lwaleli qembu kwemithi. Neuraminidase - uhlobo enzyme. Kuyinto samanje phezu ulwelwesi yazo zonke amagciwane umkhuhlane. Lapho contact ngengqamuzana zomzimba womuntu ikhishwe ezinobuthi. Lokho babangela ukubonakala izimpawu: imfiva, ubuthakathaka, ikhanda nokunye.

Neuraminidase inhibitors ukungena igciwane. Bona ukucindezela umsebenzi microorganism pathogenic, ekuvimbeleni ukubuyabuyelela yabo futhi contact letitako amaseli enempilo. Ukuthuthukiswa izidakamizwa ezifana kwaqala ngawo-1960. Eyokuqala wenza kwenzeka ngempela ukukufunda ngokuningiliziwe izindlela nethonya lazo izifo ezibangelwa amagciwane.

Neuraminidase inhibitors: izidakamizwa izithako zabo asebenzayo

kwemithi Modern inikeza lezi zidakamizwa ezimbili eziyinhloko ezingaba lungachazwa izenzo ezinjalo. Amagama abo ukuhweba "Tamiflu" futhi "Relenza". Zombili imikhiqizo ezisetshenziswa nokwelashwa kwezinkinga Umkhuhlane, nesigqi ezahlukene. Neuraminidase inhibitors zidayiswa kuphela kadokotela. Futhi akuvumelekile ukusetshenziswa imithi esibhedlela lapho kuboniswe. Ungathathi lezi imithi kwabesifazane abakhulelwe nabancelisayo. Izimo ukusetshenziswa ukuba izingane ezingaphansi kweminyaka engu-5. ukwehluleka kwezinso futhi hepatic kuyimbangela ukuze kuboniswane ukwehlukanisa ngaphambi kokusetshenziswa.

I eselaphayo yalezi mithi igama esikhethekile imodi yokuphathwa. "Tamiflu" umuthi liqukethe kule nokwakheka oseltamivir. I nomuthi kukhishelwa ngesimo amaphilisi ngokuqukethwe particulate ukusebenza kwangaphakathi. Izidakamizwa "Relenza" - lokhu kusho ukuthi uhogele. ingxenye esebenzayo zanamivir.

Umthamo amalungiselelo

Kungayiphi indlela ezisetshenziswa neuraminidase inhibitors (umkhuhlane)? Usuvele uyakwazi ukuthi kokubili imithi enqunywe udokotela wakho. Ukuze ukuthenga izidakamizwa udinga imithi. Ngakho-ke, umthamo kanye nobude ekuphathweni ngokuvamile ukhetha onguchwepheshe. Kodwa manual futhi liqukethe ulwazi ngale ndaba:

• Umuthi 'Tamiflu "abadala nezingane sebeneminyaka engu-12 sisetshenziswa kabili ngosuku iphilisi elilodwa. Isikhathi sifundo izinsuku 5. Izingane ezingaphansi kweminyaka engu-12 ubudala is mhlawumbe kusetshenziswa imali ukumiswa 30-75 mg oseltamivir (kuncike esisindo) kabili ngelanga.
• "Relenza" imithi ezilethwa yi ephefumula. Umhlahlandlela uncoma ukusebenzisa 10 mg enkompolo (2 ephefumula) kabili ngelanga. Ukuqhubeka yokwelapha izinsuku 5. Ngokuba nokuvimbela ukusetshenziswa 10 mg zomuthi kanye ngosuku izinsuku eziyi-10.

Kusebenta kanye enqabayo ukusabela

Ochwepheshe bathi inhibitor neuraminidase Umkhuhlane amagciwane aphumelela kakhudlwana ukwelashwa ngokushesha iqalisiwe. Ngakho-ke kuyadingeka ngesikhathi izimpawu zokuqala uye kudokotela uyofuna icebiso. Udokotela libeke ucwaningo oludingekayo ukuthi kuzosiza sithole amacebo esizayo. Bobabili izidakamizwa aphumelela ngokumelene Umkhuhlane amagciwane (kuhlanganise asabekayo). Ngokungafani nezinye izidakamizwa elwa namagciwane, neuraminidase inhibitors ukukhombisa ukusebenza high. amahora Kakade ezimbalwa ngemva isicelo sokuqala isiguli kuba lula.

Kubalulekile ukuthi "Relenza" futhi "Tamiflu" zingahlanganiswa nezinye izidakamizwa ukuze aphathe umkhuhlane, izimpawu zayo kanye nezinkinga. By endleleni, futhi imithi inemiphumela ethile engemihle. Ngokwesibonelo, i inhaler, "Relenza" kungabangela iphika bronchospasm. Akuvamile yokungezwani komzimba kwenzeka ngesimo edema. "Tamiflu" izindlela udle. Ngakho-ke, it has nemiphumela engemihle ngaphezulu: Ubuhlungu obukhulu besisu, njengemithi yokungezwani komzimba nokuthile, exacerbation of isifo so-renal kanye hepatic, iziyaluyalu neuropsychiatric.

Kufinyeta

Neuraminidase inhibitor ithuluzi omkhulu ekulweni Umkhuhlane amagciwane. Phakathi izibhicongo ukuze babanjwe sinombono zokuvimbela. Kodwa ochwepheshe musa ukutusa ukusetshenziswa le mithi ngokungadingekile. Ngaphezu kwalokho, awukwazi ukuthenga imithi bebodwa. Uma usokhemisi wakho unikeza ukuthenga lesi sidakamizwa "Tamiflu" futhi "Relenza" ngaphandle kadokotela, kufanele wazi ukuthi kokuzihlanganisa. Ukusetshenziswa lezi imithi angeke kuphela ukwehlisa lesi sifo, kodwa kungaba okuyisimo esisongela ukuphila. Hlala uphilile!