Imithi 'Pegasys'. Imiyalelo. incazelo

Nomuthi "Pegasys" kuyinto izidakamizwa immunomodulatory nomsebenzi namagciwane. isithako - peginterferon alfa-2a.

Nomuthi "Pegasys" manual khulumela kwesibindi kohlobo C abadala nge omuhle RNA igciwane nge isifo sokusha ihlawulelwa futhi ngaphandle ngokoma kwesibindi, kuhlanganise nalezo co-utheleleke nge-HIV (esitebeleni emtholampilo). Kulokhu, lesi sidakamizwa ingasetshenziswa kokubili wedwa futhi isebenzise inhlanganisela yazo.

Lihambisana nomuthi "ribavirin" ukulungiselela "Pegasys" imiyalelo Kunconywa iziguli kokuthola ukwelashwa ngaphambi, noma kube namthelela non-pegylated noma pegylated interferon alfa monotherapy ngaphambilini olwenziwa.

Imithi enqunyiwe abadala e kwesibindi kohlobo B okungamahlalakhona (HBeAg emihle nemibi) ihlawulelwa izilonda hepatic nezimpawu ukufanisana viral, histologically waqinisekisa cystic (noma ukuvuvukala kwesibindi) no-ALT ephakeme.

Ukusetshenziswa kwezidakamizwa "Pegasys" Umhlahlandlela incoma ukuthi ngaphansi kokuqondisa udokotela onolwazi ekufezeni ekwelapheni isifo sokusha kwesibindi kohlobo C no Yiqiniso ezingamahlalakhona.

Ngo ekwelapheni nomuthi "ribavirin" isetshenziswa ngokuhambisana isichasiselo nalokho.

Umuthi 'Pegasys "imfundo ivumela ukungena kuphela ethangeni noma ngaphambili odongeni peritoneum kanye ngesonto. Umjovo wenziwa phansi kwesikhumba.

Ngaphambi ukwethulwa izidakamizwa kumele sibukwe. Isixazululo akufanele aqukethe ukungcola. Umuthi akufanele ukushintsha umbala. Udokotela kufanele ifundise iziguli isitoreji efanele kwemithi. Izinto ezisetshenziswa kumele ilahlwe. Musa kabusha ukusetshenziswa Izinalidi nezipetu.

Lapho HBeAg-negative futhi HBeAg-HIV ne-hepatitis ezingamahlalakhona B ukugeleza linqume izidakamizwa "Pegasys 180" kanye njalo izinsuku eziyisikhombisa. Isikhathi monotherapy - amasonto amane nesishiyagalombili ka ikhumbula genotype.

Lapho kwesibindi kohlobo C. imisinga iziguli ongakayisebenzisi ziphathwe ukwelashwa izidakamizwa liyasetshenziswa kanye ngesonto. Umthamo watusa - 180 mg wedwa noma lihambisana "ribavirin" izidakamizwa.

Umuthi is contraindicated in iziguli isifo sokusha kwesibindi kohlobo sokuhlasela kwamasosha omzimba, isifo sokusha decompensated, ezinzima isibindi isifo, i-hyperthyroidism, i-hypothyroidism, isifo sikashukela esiteji decompensated. Musa akunikeze imithi "Pegasys" e ezinzima isifo senhliziyo ngo esiteji decompensation, kuhlanganise kabi elawulwa, ukugeleza engazinzile phezu esandulele izinyanga eziyisithupha. Izidakamizwa is contraindicated ezingaphansi kweminyaka emithathu, uma hypersensitivity-alpha interferon, kanye imikhiqizo imfucuza Escherichia coli, polyethylene glycol noma yimuphi omunye izithako imithi.

Ngo isicelo yokwelapha kuhlangene imithi, "Ribavirin" kufanele kubhekwe contraindications ke.

Hepatitis C ukusetshenziswa kwezidakamizwa "Pegasys" ngesikhathi sokukhulelwa akuvunyelwe. Uma kudingekile, faka i-esebenzisa abesifazane lactating, kufanele anqume ngalolo ekunqanyulweni kwe lactation.

Ngokuqapha ezinqunyiwe iziyaluyalu zenhliziyo kanye sokuhlasela kwamasosha omzimba, ukucindezeleka (kuhlanganise umlando), psoriasis.

Ngokuvamile lisho 'Pegasys' ebekezelele ngokubhekakade kahle. Nokho, kwezinye izimo ngamunye ukusabela ezingezinhle. Ngokuvamile, ngemva ukwehlisa umthamo 135 UG imiphumela engathandeki kuyaqedwa.

Mayelana nemithi "Pegasys" libuyekeza Ochwepheshe ngokuvamile omuhle. odokotela abaningi bathi kusebenta ukumelana izidakamizwa futhi umphumela izuzwe. Ngaphezu kwalokho, i-nomuthi is kahle ikubekezelele iziguli. It is kuyaqabukela ebonwe ukwelashwa nge izigameko ezingezinhle ezavela okuhlotshaniswa advantageously ngozwelo eliphezulu.

Ukwelashwa nge "Pegasys" kufanele kwenziwe kuphela ngaphansi kweso lwezokwelapha.