Glatiramer acetate: incazelo izinto

Multiple sclerosis - a umonakalo isimiso sezinzwa esiyinhloko njalo ngayo. Izifo abantu singangena abasha phakathi yobudala: at-engozini iqembu kuhlanganisa abesilisa nabesifazane abaneminyaka engu-15 kuya kwengu-40. Enye yezindlela ezisetshenziswa uphathwa acetate glatiramer. On kuzoxoxwa ngawo kulesi sihloko.

yi-multiple sclerosis: izindlela, izimbangela, izimpawu

Isici esiphawulekayo isifo esivela nezinye izifo ukuthi kuthinta izingxenye eziningana isimiso sezinzwa, engibukhulumile ngaso isiguli ubukisa izimpawu ezahlukene zezinzwa. Ethunyelwayo multiple sclerosis kuyinto esizalwa naso: nezikhathi kushintshana ka exacerbation kanye ukuthethelelwa.

Umfutho ukuthuthukiswa lesi sifo ukubhujiswa nerve ulwelwesi ku asebuchosheni nomgogodla, okuholela multiple sclerosis (izikhungo) kumiswa zingcwecwe. osayizi yabo lisukela amamilimitha angu ambalwa ngamasentimitha ambalwa. Phakathi exacerbations bathambekele imfundo zingcwecwe ezinkulu ikakhulukazi.

Kuze kube manje, imbangela isifo bengayiqondi ngokugcwele. Nokho, abanye bakholelwa ukuthi yi-multiple sclerosis is kubangelwa inhlanganisela yezici zangaphakathi nezangaphandle. Ukuze labo zihlanganisa:

• Ezifweni izifo (ezibangelwa amagciwane kanye ezibangelwa amagciwane).
• Ukuchayeka emisebeni enamandla ezinobuthi.
• Ukungondleki.
• yokuhlala Geoecological.
• ukulimala njalo.
• nezimo ezicindezelayo njalo.
• yofuzo.

symptomatology

Imiphumela yaloku kuhlola okungenhla senziwa kudokotela oyisazi sezinzwa ngezindleko uma izimpawu zenzeka:

• Eliqhaqhazelayo izandla, imilenze, umzimba. Isiguli kunzima ukubamba ngezandla zabo izinto, kungakhathaliseki ukuthi kungcono ngisho ngesipuni noma ipeni obungangenhloko kakhanjana.
• Incoordination.
• Nystagmus - okusheshayo, ongalawuleki iso ukunyakaza.
• Buthaka (noma ephelele ukunyamalala) ingqondo.
• Ushintsho ukunambitheka izintandokazi, kwesisindo.
• Ukuba ndikindiki, ubuthakathaka ezingalweni nasemilenzeni.
• Isiyezi kanye nokunye ukwephulwa vegetososudistye.
• Paresis we izinzwa ebusweni kanye trigeminal.
• Ubuthakathaka ezingabantu, iziyaluyalu kokuya esikhathini kwabesifazane.
• Nciphisa e acuity ezibukwayo.
• inkulumo Slow.
• Dysmotility.
• zengqondo (ukucindezeleka, bajabula, kanjalonjalo.).
• zesifo sokuwa.

ukuma

Kukhona amafomu ezintathu-multiple sclerosis:

• Cerebrospinal - okuvame kakhulu. Libhekene izilonda kusaqalwa lesi sifo sendaba omhlophe kuzo zombili umgogodla kanye nobuchopho.

• Cerebral - ukunqotshwa ndaba ezimhlophe zobuchopho. Kuhlanganisa izinhlobo eziningana - cerebellar, isiqu, cortex futhi iso.

• Emgogodleni - lesion umgogodla.

Glatiramer acetate e-multiple sclerosis

nomuthi Kubhekwe iphathelene immunomodulators iqembu. Limelela usawoti uskusnokisluyu kwakhiwa zemvelo amino acid L-tyrosine, L-glutamic acid, L-alanine, L-lysine. Izinguquko izidakamizwa ngesikhathi lesi sifo, ine immunomodulatory umphumela wendawo. Ukusetshenziswa glatiramer acetate futhi ngokulungile ngesikhathi ukuthethelelwa, kusukela kulokhu kusho kunciphisa ukuvama exacerbations futhi kuvimbela ukuthuthukiswa izifo zezinzwa.

izinkomba

Izinkomba ukusetshenziswa zomuthi akuyona kakhulu. Lezi zihlanganisa:

• Ethunyelwayo multiple sclerosis. Kulokhu, acetate glatiramer isetshenziswa ukunciphisa exacerbations kanye deceleration yezinkinga isifo isici.
• Emtholampilo isehlane Syndrome, aqhubeke kanyekanye ukuvuvukala evelele edingekayo corticosteroids emthanjeni. Ngesikhathi esifanayo imithi enqunyiwe esetshenziswa ukubambezela ukwedlulela lesi sifo ngendlela ngokucacile multiple sclerosis.

Izimo

Njengoba kunjalo nge imithi kakhulu, ukusetshenziswa glatiramer kungavunyelwe:

1. Uma isiguli hypersensitive emuthini (kuhlanganise mannitol).
2. Phakathi nokukhulelwa kanye lactation.
3. Kufika engu-18 ubudala (nephephe ezingazange wafunda).

Ngaphezu kwalezi Izimo, kukhona ukulinganiselwa. Ngokwesibonelo, uma isiguli nezici ezithile ukuze izinhlobo ezahlukene komzimba, kanye pathologies sokuhamba kwegazi neziyaluyalu obusebenzayo izinso ukusetshenziswa kwezidakamizwa kungenzeka, kodwa kuphela ezimweni ezimbi kakhulu futhi ngaphansi kweso lwezokwelapha.

side effects

ukusabela ezingezinhle ukuba ukusetshenziswa kwezidakamizwa isekelwe into ezifana glatiramer acetate, ezihlukahlukene kakhulu. Ngakho-ke, zihlukaniswe amaqembu:

1. System Immune: hypersensitivity, ukushaqeka anaphylactic, angioedema.
2. uhlelo hematopoietic: okuvela izifo ezifana leucopenia, leucocytosis, lymphadenopathy, ushintsho isakhiwo lama-lymphocyte, thrombocytopenia futhi splengomegaliya.
3. uhlelo endocrine: i-hyperthyroidism.
4. Isimiso sezinzwa: ikhanda kungenzeka, ukucindezeleka kwengqondo, ukukhathazeka, uvalo kwesasa, Ukudlikizela, kahle imoto umsebenzi, stupor, kanjalonjalo.
5. Kusuka umzimba:-ke kungabonakala nasemkhakheni njengoba ukwanda isisindo somzimba, noma ukuzincisha. Ngaphezu kwalokho, kungase kube hyperlipidemia, hypernatremia, sifo.
6. Ukuzwa ukulahleka, ikhanda.
7. Izinhlaka umbono: diplopia, umonakalo corneal, ale nkinga, yoma optic, isici emkhakheni umbono, angaboni kahle.
8. Isimiso senhliziyo nemithambo yegazi: tachycardia, tachycardia paroxysmal, emithanjeni varicose, kukhuphuke blood pressure.
9. wokugaya ukudla: isicanucanu, ukuhlanza, nesifo, ukubhodla, ukopha rectal nokunye.
10. uhlelo zokuphefumula: ukukhwehlela, rhinitis zonyaka, iphika, hyperventilation. Laryngospasm.
11. Isibindi kanye biliary izindlela: cholelithiasis.
12. uhlelo urinary: pollakiuria, hematuria, nokugcinwa urinary.
13. izicubu Ongama nesikhumba ukulunywa, contact dermatitis, urticaria, erythema nodosum nokunye.
14. Zemisipha System: arthralgia, iqolo nentamo, samathambo, bursitis, i-osteoarthritis, kanjalonjalo.
15. Izitho zangasese futhi nezindlala mammary: nomjikelezo wokuya esikhathini, anda umdlavuza webele, Erectile Dysfunction.
16. Chills, ukukhathala, ukopha acinene, imfiva, ukuvuvukala, ukulimaza kanye nokunye. Izimpawu.

Ukuxoxa Izidakamizwa

Umbuzo esebenzisa nokuxhumana ngesisekelo glatiramer acetate nezinye izidakamizwa engakaze wafunda kuze kube sekupheleni. Ukusebenzisana nokusetshenziswa kanyekanye ne izidakamizwa isetshenziswa ukwelapha multiple sclerosis, ke ayivezi (esekelwe ukusetshenziswa angumfelandawonye ejenti ngenhla izinsuku ezingu-28). amathuba aphezulu komzimba nezinto wendawo.

ukweqisa izidakamizwa

Kuze kube manje, i-data esekhadini izigameko ezingezinhle ezavela nge ukweqisa izidakamizwa zomuthi akuyona. Uma yonke le nkathazo kulo efanayo iphutha, isiguli kufanele kube ngaphansi eduze kweso lwezokwelapha. Kufanele isimo jikelele isiguli, kanye nokunikeza ukwelashwa lingaze futhi basekelane.

Glatiramer acetate: yokusetshenziswa

20 mg we phansi kwesikhumba izidakamizwa iqondiswa kanye nsuku zonke. Kungcono ukugcina isheduli: umjovo Kunconywa ukubeka esikhathini esifanayo. Uma nganoma isiphi isizathu ukuqokwa is ezingabanjwanga ke izidakamizwa kufanele ufake ngokushesha ngokushesha ngangokunokwenzeka ukukhumbula. A umthamo double akufanele wagwaza.

izidakamizwa Iphathwe avunyelwe ezinqeni, okhalweni, futhi izandla nesisu (isikhala paraumbilical at ibanga 5 cm). I bloodshot futhi ezishintshe umbala izindawo isikhumba nezindawo ngezimpawu imijovo ungafaki. Thatha isiqunto sokujamisa ukwelashwa kufanele kube udokotela.

ukusebenza

Ingabe okuhle glatiramer acetate? Izibuyekezo aqukethe ulwazi mayelana imiphumela ngempumelelo kakhulu kusaqalwa ekulweni multiple sclerosis. Abantu abaningi ukuzwa imiphumela engemihle ngokushesha ngemva umjovo we izidakamizwa. Nokho, ziyisici esikhathi esifushane futhi ngokwabo. Uma uhlangabezana izimpawu ezinamandla, ngokushesha kudokotela, futhi kwezinye izimo - lokubiza i-ambulensi.

Ezimweni ezingavamile, abaphathi ezingamahlalakhona zomuthi angagcina isikhumba necrosis futhi lipoatrophy kusayithi umjovo. Ukuvimbela imiphumela enjalo kufanele ulandele kuphela ukulandelana izitho zomzimba ngoba umjovo.

igama Trade, umkhiqizi

Glatiramer acetate unegama ezahlukene ukuhweba. Kodwa kamuva lesi. Kwaphela isikhathi eside, ngaphambi ukuqedwa kwenkontileka nenkampani Israeli, umphakeli Teva, imikhiqizo imakethwa Ltd. "Biotech". Glatiramer acetate isiyatholakala ngokusebenzisa kakhulu Teva inkampani waseRussia "Teva".

Ukuqoka umuthi yawo-multiple sclerosis, udokotela ngokuvamile izobonisa igama Indlela: "Copaxone Teva." Nokho, lena akuyona kuphela eyindlela, ketshezi esebenzayo eyinhloko esikhathazeka ngayo acetate glatiramer. Analogs zisabalele, lezi zibandakanya:

• "Copaxone 40".
• "Glatirat".
• "Aksoglatiran FS".
• "Timekson".

Uyini umehluko kusho "Copaxone Teva" futhi "Copaxone 40", eqinisweni, sinye siyafanana izindlela? Ingqikithi asebenzayo kuzo ngokulinganayo - acetate glatiramer. Synonyms kukhona umthamo ezahlukene futhi kungakho intengo.

Ziqaphele impilo yabo, ngesikhathi ukuya kudokotela futhi unakekele abathandekayo!