Amasosha Omzimba ukuze TPO futhi umthelela wabo ohlelweni hormone

Amasosha Omzimba ukuba tereoperoksidaze inethonya ohlelweni womuntu namangqamuzana futhi ezithinta impilo yakhe kanye operation evamile. Isethi ejwayelekile izifundo wegazi hormone uma uhlola operation yegilo kuhilela ukuthola ezingeni TSH, i-T3, T4 CT3, FT4 futhi AT ukuze TPO. Ngaphambili, amasosha omzimba TPO ku izincwadi zezokwelapha ezisekelwe ekwazisweni esibizwa izidumbu antimikrosomalnymi.

Phakathi operation evamile yegilo masosha omzimba TPO igazi ongekho noma samanje ngemithamo emincane kakhulu. Inani lawo landa kakhulu yezifo sokuhlasela kwamasosha omzimba. Ukulinganisela eliphakeme alotshwa thyroiditis Hashimoto sika. Lesi sifo ngokuvamile kwenzeka kwabesifazane asebekhulile. Amathuba ukunqoba amalungu thyroiditis Hashimoto yomndeni owodwa, sengathi lesi sifo ngokwalo nezici ezithile njengefa idluliselwa ezakhini zofuzo. Abantu ne ukuguquka kwezakhi zofuzo chromosomal babe nengozi enkulu ekuzuzeni isifo.

Amasosha Omzimba ukuze TPO atholakala iziguli-Graves 'disease. Ngo ngokukhukhumala kwentamo goiter hyperfunctioning yegilo indlala inyuka ngobukhulu, isiguli ekhononda ka tachycardia, arrhythmia, eliqhaqhazelayo kwamalungu omzimba, izinkinga nezinkophe namehlo. A ngokweqile elincane amagugu avumelekile amasosha TPO egazini kungase kubonise hypothyroidism. I-hypothyroidism kubambezela umzimba, kwandisa nengozi yokukhuluphala, kanye umthamo encishisiwe ngomsebenzi, umuntu njalo azizwa ukukhathala, ukucobeka, izinkinga zokukhumbula noma ukugxilisa ingqondo. Uma amasosha omzimba TPO atholakala emzimbeni nokuthumba owesifazane owayezithwele, kungenzeka ukuthuthukisa i-hyperthyroidism emva kokuzalwa ingane yakhe ngekhanda. Ukuthuthukisa esibelethweni, ingane kungenzeka nezici ezithile lidlule iziyaluyalu hormone.

Ukuze uhlole indlala yegilo, ngokwanele ukuze aphumelele kulesi sivivinyo. Amasosha Omzimba ukuze TPO ziphenywe serum igazi, igazi umthambo kuyadingeka ukuba kudlule ekuseni esiswini esingenalutho. Ngaphambi kokuqoqa izinto eziphilayo azithathe isifundo, kuyatuseka ukuba isimo ukuphumula; isimo ujabule kungathinta uketshezi hormone. Ngolunye usuku ngaphambi kokubeletha yokuhlaziya ukubekela eceleni ukuzikhandla okhandlayo, utshwala nogwayi.

Ziyini izimiso zokuziphatha elivumelekile, ezingasetshenziswa ukubonisa ukuhlaziywa amasosha TPO? Kuyinsakavukela omzimba zokhahlamba kusuka 0 kuya ku-30 amayunithi ngamazwe ngemililitha ngayinye. Kodwa uma imiphumela izifundo eqoshiwe Imiphumela kancane ngenhla evamile, ningatatazeli. Nge uketshezi anda thyroxine futhi triiodothyronine omzimba ukuba TPO ukuvikela ukuthuthukiswa hyperthyroidism futhi thyrotoxicosis. Nokho, ephansi score, aba maningi namathuba okuba kancane ukuze uthole isifo sokuhlasela kwamasosha omzimba kakhulu eminyakeni yokuguga. Ngemva kweminyaka engu-30, isibalo amasosha yegilo peroxidase e serum iba kancane ephakeme.

Amasosha Omzimba ukuze TPO ziqala ukuba elakhiwe uma ileveli hormone yegilo-inkanuko egazini iba ephakeme. Amasosha omzimba equkethwe yomzimba, nzima kakhulu uketshezi of T3 ne-T4, umzimba kancane. Futhi, ngesizathu ukubukeka amasosha omzimba isinyathelo ngokwandisa cytokine eqeda ukuvuvukala. Kulokhu, kukhona emakamu anda amasosha thyroglobulin.

Imiphumela ukuhlaziywa kwama-hormone egilo uzilungiselele kuya ezinsukwini eziyishumi ezintathu. Izindleko yokuhlaziya kuyahlukahluka ruble 100 kuya 400 kuncike esifundeni kusuka. Izinkomba omzimba ukuba TPO ayikwazi uhlolwa ngaphandle idatha mayelana nentuthuko we-hormone yegilo-inkanuko, lizinga triiodothyronine kanti thyroxine, ngalokho emakamu igazi kwama-hormone egilo a khulula, non-amaprotheni fomu. Kuphela zihlolisisa isimo zezifundo hormone endocrinology kuzosiza uthole imithi ekufanele esimweni ngasinye.