"VFS": yokusetshenziswa. Analogs, ukubuyekezwa kanye contraindications "VFS"

"VFS" Tablets iqembu unqambothi ejenti antiarrhythmic. Umuthi uyakwazi ivimbela iziteshi sodium e Ulwelwesi lwamangqamuzana cardiomyocytes. It kuphakamisa okwehlisa intraventricular futhi conduction atrioventricular sifushanise tekusebentisa ngempumelelo nezikhathi refractory ku Atria, besigaxa block legatsha, AV-node kanye Purkinje zesivikelo sesifuba. Kusho nhlobo nomthelela isikhathi qt-isikhawu, imvamisa Kufinyeta. In the ukungabikho ukubonakaliswa kokuqala enganele umsebenzi inhliziyo, izidakamizwa "VFS" (incwadi yeziyalezo iqukethe ulwazi ezifana) akunamthelela contractility esivimba amanzi. It akuphazamisi conductivity we atrioventricular engeyokuqala anterograde isiqondiso. Agent akunamthelela enqabayo hypotensive. Ngo umkhuba ke akufanele kumakwe ithonya inotropic. Lapho ethola imithi engasenamahloni ku automaticity itheku engeyokuqala. It has antispasmodic, izinzwa wendawo, kanye ngokulinganisela isinyathelo anticholinergic abangenalo emitholampilo ukubaluleka degree. It has koronarorasshiryayuschee kancane, izakhiwo sine. Umthelela uphawu temlomo amane noma imizuzu ayisithupha. It ifinyelela umsebenzi esiphezulu emva kwemizuzu 80. Isikhathi isinyathelo zokwelapha - by 8 amahora.

Pharmacokinetics ezimweni jikelele

I bioavailability cishe 40%. Umuthi is akheka esibindini futhi ezikwazi ukuhlaba zingene Bbb. Excretion zomuthi kwenzeka umchamo. Lapho ukwephula kwezinso isikhathi umsebenzi excretion luyanda izikhathi 2-3.

What means "VFS" izinkomba ukusetshenziswa?

Umuthi kuboniswa ngenxa ventricular futhi extrasystoles supraventricular, paroxysmal tachycardia kanye nohlobo (akukho izilonda enhliziyweni i nature organic syndrome WPW), flutter atrial futhi paroxysms atrial.

Umthamo lwemithi

Ukulungiselela "VFS" imfundo manual uncoma umthamo - 25 mg 1 isikhathi ngasinye 8 amahora. In the ukungabikho express yi zokwelapha nomuthi ezithathwe njalo ngemva kwamahora 6. Kwezinye izimo ezivunyelwe avuke umthamo kabili olulodwa (50 mg). Isikhawu isikhathi kulokhu amahora 6-8.

Usuku elivunyelwe hhayi ningi than mg 300. Isikhathi yokwelapha kanye bakwazi ukulungisa wesifunda ethola onguchwepheshe isethi. Medicine isiphuzo emva kokudla. Eyochoboza noma yokuchitha ithuluzi akuvunyelwe.

Nomuthi "VFS": side effects

Ngokweyame ezinhlinzekweni kadokotela nemiyalelo izidakamizwa ikubekezelele iziguli ezineminyaka yonke muhle ngokwanele. Nokho, kukhona kungenzeka nemiphumela engemihle ngesisekelo yokwelapha izidakamizwa "VFS". ngaleyo ndlela Imiphumela engemihle ingase ibe ntshashintshe of kobukhulu. I-ejenti kungaba avuse yokuphazamiseka imisebenzi amasistimu neuropathy sezinzwa. Ikakhulukazi, kukhona isiyezi, diplopia, ataxia. Phakathi la imiphumela emibi umthelela izidakamizwa senhliziyo uhlelo ochwepheshe uqaphele ukwephulwa okusobala conduction intraventricular futhi atrioventricular, ukuthuthukiswa itheku tachycardia (ukwelashwa eside). ukubonakaliswa ukugula umphumela arrhythmogenic, yokwandisa iminyaka QP ebanga, ukunwetshwa izinguquko QRS-eziyinkimbinkimbi nezinye ephethenini ECG. Ngesisekelo yokwelapha izidakamizwa "VFS" (incwadi yeziyalezo esixwayisa ke) ubonakala ububomvu kwesikhumba, ubuhlungu ekhanda noma umuzwa wobukhulu. Ezinye iziguli ukuzwa ukusabela nomzimba (ukuqubuka noma isikhumba ukucasuka). Liqukethe ulwazi mayelana nemiphumela engemihle yemithi "VFS" imfundo manual. Izibuyekezo ochwepheshe eliphathelene nelungiselelo obukhulu, ngokuvamile, omuhle. Nokho, unikezwa ukungathi sína ezinye emibi zomuthi wenziwa khona ngaphansi kokuqondisa eduze zikadokotela.
Esimeni ngenxa yezinkinga ukuwohloka kufanele uvakashele ngokushesha onguchwepheshe. Kulokhu, udokotela angase akhethe esikhundleni kusho "VFS" izidakamizwa ezifanayo.

Lapho hhayi eyabelwe imithi?

Izimo zihlanganisa ukushaqeka cardiogenic, vimba atrioventricular esigabeni lesithathu nelesibili (ngokungabi bikho yokufakelwa inhliziyo isigqi somshayeli). Akuvunyelwe ukuba baphuze ikhambi ophakeme wegazi esikhathini esinzima (systole ingcindezi engaphansi kuka-90 mm / HG.), Hypertrophy e myocardium ka-ventricle engakwesobunxele libizwa. izidakamizwa ezivinjelwe lapha cardiosclerosis post-infarction. Umuthi akunconyelwe nokuvinjelwa ilungelo umlenze besigaxa legatsha block (lapho kuhlangene iziyaluyalu egatsheni ohlangothini lwesobunxele), ezingamahlalakhona inhliziyo ukwehluleka umsebenzi nokulinganisela ezinzima. Contraindicated imithi iminyaka engu-18 (ngenxa yokuthi ukuthi hhayi kusungulwa ukuphepha nokusebenza ngempumelelo amanxusa), fructose ukungabekezelelani. Akuvunyelwe ukuthatha imithi abantu sifo ka kahle resorption galactose / glucose, ukukhulelwa, isomaltase kusilela / sucrose. Akunconyelwe kwezidakamizwa hypersensitivity kuya izingxenye. Uma ufuna ukuchitha yokwelapha amanesi ukuze isiguli, ufuna ukumisa lactation.

Lapho udinga ukulungiswa umthamo?

Ngezinye izikhathi kukhona isidingo sokushintsha amathuluzi "VFS" ethola wesifunda. Imiyalelo, amazwana kusukela ochwepheshe eziqukethe ngayo ukwaziswa inciphise izidakamizwa noma ukwandisa isikhawu phakathi ngemithamo kungenziwa Kunconywa sokuvimba atrioventricular ezingeni lokuqala, e intraventricular conduction neziyaluyalu, bradycardia. Isexwayiso athobele engela-Ukuvalwa ukufiphala iziyaluyalu kwegazi (neuropathy) imvelo esindayo hypertrophy e wendlala kwezicubu. Ukulungiswa izifunda kudingeka ngesisekelo electrolyte umzimba sishintsha conductivity e Purkinje endwangwini, nokuvinjelwa omunye imilente block besigaxa legatsha. Kudingeka ukuqapha lapho ithola neminye imithi antiritmicheskih kanyekanye ne imithi "VFS". Izibuyekezo lochwepheshe abaningi kuyinto ngenkani kakhulu endabeni izinguquko Isikali kungekho nomphumela.

Ukuze uthole ukwaziswa okwengeziwe,

Ngaphambi kokuqala imishanguzo aqede iziyaluyalu amanzi electrolyte ukulinganisela inqubo kokuthola imithi kuyadingeka ukuqinisekisa ukulawula njalo nangokucophelela phezu kwalo. inhliziyo ukushukuma embundwini kungase kwandise ezigulini eziye ngamelwa yinhliziyo (acute), ukuhluleka kwenhliziyo, noma une-pacemaker yokufakelwa. Esimeni isiyezi, umbono double, ikhanda Kunconywa ukunciphisa umthamo. Lapho tachycardia itheku ngesisekelo ende reception izidakamizwa beta-blocker babelwa njengoba kudingeka. Lezi amalungiselelo yanconywa ngemithamo ongaphakeme. Ngesisekelo ukwelashwa kufanele uqaphele lapho imisebenzi imisebenzi engase ibe yingozi okudinga kunakwa okuhlushwa okusheshayo noma ukuphendula.

ukweqisa izidakamizwa

Ngenxa yokuthi lo muthi has a ububanzi ongaphakeme womsebenzi zokwelapha, ukudakwa ezinzima singenzeka kalula ngokwanele. ingozi okusezingeni eliphezulu Ikakhulukazi ubuthi ekwamukelweni nezinye izidakamizwa antiarrhythmic. Ngo ukweqisa izidakamizwa imakwe ukunwebeka PR- futhi qt-ngezikhawu, amplitudes ukwandisa T-wave ukunwetshwa QRS-eziyinkimbinkimbi. Against ngemuva lokudakwa kuphakama asystole, bradycardia, kwehle contractility e myocardium. Isiguli is yaphawula sinotrialnaya ukuvinjelwa, ekunciphiseni ingcindezi sho wokugaya ukudla uhlelo iziyaluyalu. Ukudakwa kuhambisana paroxysmal polymorphic ventricular tachycardia, angaboni kahle, isiyezi, ubuhlungu ekhanda. Esimeni ukweqisa izidakamizwa ukwelashwa lingaze kuboniswa. Ukwelashwa nokuvikelwa ventricular tachycardia Kwenziwa ukusetshenziswa kwezidakamizwa antiarrhythmic isigaba mina Mina C Ukunwetshwa QRS-eziyinkimbinkimbi, hypotension futhi bradycardia iqedwe sodium hydrogen carbonate.

Ukuxhumana nabanye ukuthaka imithi ngendlela

Lapho kuthathwe kanye inducers ka microsomal hepatic enzyme izidakamizwa kusebenta "VFS" liyancipha. Lokhu kwandisa ingozi nemiphumela anobuthi. Lapho ethola izidakamizwa antiarrhythmic nezinye amakilasi anda amathuba wokuthuthukisa ithonya arrhythmogenic. Ithuluzi futhi sithuthukisa umsebenzi non-depolarizing imisipha relaxants.

Yikuphi kukhona izidakamizwa ngempumelelo nge indlela efanayo yokwenza izinto?

Kusho "Allaritmin" iqukethe ikhemikhali ezisebenzayo ezifanayo umuthi "VFS" - hydrobromide lappaconitine. I nomuthi libhekisela isigaba mina izidakamizwa antiarrhythmic. "Allaritmin" Umuthi itholakala ifomu tablet futhi njengoba isixazululo umjovo ku umsipha noma emthanjeni. Lapho ezithathwe ngomlomo, umphumela nomuthi kwenzeka cishe ihora. Ngemva kwamahora angu-4-5, ifinyelela ngempumelelo enkulu. Isikhathi umphumela - 8 amahora noma ngaphezulu. Ukwethulwa umphumela non zomuthi kwenzeka ngokushesha - kungakapheli imizuzu 15-20. Ngokungafani nomuthi "VFS" kusho "Allaritmin" Kunconywa isiphuzo izikhathi 3 nsuku zonke 25 mg. Thatha imithi kufanele kube ngaphambi kokudla. Tablets wayichoboza ezifiselekayo. Uma kwenzeka yokuntula kusebenta kungase umthamo kanye nokuvama reception anda. Ukuphatha i-intravenous Kwenziwa kancane, imizuzu engaphezu 5. ngaleyo ndlela Isikali setha ngokuvumelana isisindo sesiguli. Kunconywe ngu 0.3-0.4 mg / kg. Kwezinye izimo (ikakhulukazi ezinzima) izidakamizwa iqondiswa ngokuphindaphindiwe phezu amahora 6. Ngo imisipha iqondiswa 0.4 mg / kg ngezikhawu amahora 6. Kuyaphawuleka ukuthi abaphathi emthanjeni is hhayi Kunconywa ukuba afeze ekhaya. Izidakamizwa "Allaritmin" has ngemikhawulo efanayo ekusebenziseni umuthi "VFS". Ukwelashwa Kwenziwa esibhedlela ngaphansi kweso njalo udokotela kanye nokuqapha ECG. Lokhu kubalulekile ikakhulukazi nokwelashwa kweziguli wokuqala degree block atrioventricular, ukuhluleka kwenhliziyo, decompensated ezingamahlalakhona Yiqiniso hlobo.

isiphetho

Kusho "VFS", ukusetshenziswa okumele lilawulwa, njengabanye antiarrhythmics, kungokwalabo esigabeni izidakamizwa ezinamandla. In the ukungabikho nomphumela oqabulayo akufanele ukwandisa yayo uma lithatha umthamo onqunyiwe onguchwepheshe. Lokhu kungenxa yokuthi kunobungozi adakwe yezinkinga okwalandela. Ngaphambi kokunika izidakamizwa, udokotela kufanele ogulayo uyaziqaphela imiphumela engemihle kanye contraindications. Ngakwelinye ihlangothi, isiguli sikutshela mayelana nokuba khona ukungabekezelelani, kufaka phakathi umlando, noma ngayiphi abezindaba, kanye nezidakamizwa kuthatha owengeziwe. Ngaphambi kokuthatha lesi imithi kufanele uhlole isichasiselo.