'Sulfasalazine' izindlela. Yokusetshenziswa

Umuthi 'sulfasalazine EH "kuyinto anti-inflammatory, anti-rheumatism, immunosuppressive, emathunjini ejenti bacteriostatic. Lo mshini wezenzo kusekelwe esebenzayo izidakamizwa ingxenye izakhiwo.

Ngempumelelo salazosulfapyridine ketshezi kuyinto i-antibiotic kusukela iqembu sulphonamides. Uphiko has a umsebenzi bacteriostatic ngokumelene gonococcus, streptococci, diplococci, E. coli.

Active isithako 5-aminosalitsillovaya acid anezakhi eqeda ukuvuvukala, kunomthelela nokucindezela prostaglandin zamagama kanye okusithiyayo of cyclooxygenase.

Kusho "Sulfasalazine" (umyalelo ukusetshenziswa iqukethe ulwazi ezifana) amabhlogo ushintsho lymphocyte futhi kuvimbela monocytes. Umuthi sithinta yeselula, futhi amasosha omzimba humoral.

I nomuthi ayiqondakali amuncwa kusukela pheshana emathunjini.

Umuthi 'Sulfasalazine "imfundo manual uncoma ukuthi proctitis izilonda emathunjini, nesifo nonspecific (izilonda emathunjini). Kulezi pathologies, le nomuthi esetshenziswa ekwelashweni kwe-exacerbations futhi yokwelapha yesondlo ukuthethelelwa.

Kusho "Sulfasalazine" imfundo manual uncoma e isifo Crohn (at amafomu nokulinganisela sibi exacerbation).

Umuthi nayo engabelwe-rheumatoid arthritis (engamahlongandlebe kanye).

Nomuthi "Sulfasalazine" imfundo manual incoma ukuthi ngemuva kokudla. I Isikali kumele kusungulwe ngamunye ngokuhambisana ngobucayi izimpawu futhi imiphumela engemihle.

Ngokuvamile, umuntu omdala ayewabelwe angu 500 2000 kane ngosuku ukuze badambise isifo. Ngemva kwalokho, isiguli idluliselwe ukwelashwa yesondlo. Umthamo kuleli cala - 500 angu kathathu, kane ngosuku. Ubude besikhathi sokwelashwa - kwezinyanga ezimbalwa.

Umthamo izingane: ezinhlanu kuya eminyakeni eyisikhombisa - izikhathi 250-500 angu ezintathu kuya kweziyisithupha ngosuku, iminyaka eyisikhombisa - izikhathi 0.5 amagremu ezintathu kuya kweziyisithupha ngosuku.

Adult umthamo zokwelapha - 1.5-3 amagremu. Njengoba umkhuba ubonisa, umphumela kwenzeka ngemva nje kwamasonto ayisithupha kuya kwayishumi. Qhubeka ukwelashwa izinyanga okungenani eziyisithupha.

Umuthi is contraindicated ezimeni kwegazi, porphyria oluboniswa iziyaluyalu kwesibindi noma izinso, hypersensitivity (kufaka phakathi salicylates, sulfonamides). Musa linqume izidakamizwa "Sulfasalazine" izingane kuya eminyakeni emihlanu. Is contraindicated ngesikhathi lactation. Uma kudingekile, ukusetshenziswa imithi ngesikhathi ibele, kumele anqume ngalolo ekunqanyulweni kwe lactation.

Phakathi nenkathi yokukhulelwa, le izidakamizwa ingasatshenziswa ngokuqinile ngokuvumelana izinkomba e ubuncane umthamo zokwelapha ngaphansi kweso lwezokwelapha. Asincomi ngokuthatha izidakamizwa "Sulfasalazine" ku senyanga yesithathu yokukhulelwa.

Iningi izigameko ezingezinhle ezavela Isikali nomuthi incike yokutholwa futhi umphumela womsebenzi salazosulfapiridina (isithako esebenzayo).

Umuthi kungabangela nephropathy neuropathy, isiyezi, nephritis interstitial, ukuqwasha, tinnitus. Phakathi ekwelapheni iziyaluyalu kungenzeka izinso, isifo sohudo, ukuntuleka kwegazi emzimbeni, izilonda kule wamaphaphu izicubu, leukopenia, ukungazali kanye oligospermia (lezivakashi). ukusabela ezingezinhle futhi zihlanganisa ukuhlanza, pancreatitis, agranulocytosis, ukushaqeka anaphylactic, ukuntuleka kwegazi emzimbeni, urticaria. Ezimweni ezingavamile, lesi sifo kungabonakala nasemkhakheni neuropathy kwemizwa uhlelo umsebenzi, isikhumba ukusabela.

Ngokuhamba ukusetshenziswa kwezidakamizwa Kunconywa ukuba siphuza neziphuzo kakhudlwana.

Abukho ubufakazi ukuthi lesi sidakamizwa "Sulfasalazine" analogs we ketshezi esebenzayo.

Ngaphambi kokusebenzisa izidakamizwa, ochwepheshe batusa ukuba bajwayelane isifinyezo.