Umdlavuza pancreatic

umdlavuza pancreatic kuyinto neoplasm abulalayo, kwakhiwa kusukela amaseli obumba amanyikwe. Uhlobo oluvame kakhulu lomdlavuza, yimaphi ama-akhawunti kuze kube-95% kuzo zonke izimo lokhu isimila kuyinto adenocarcinoma, okuyinto eba ngaphakathi ingxenye exocrine amanyikwe. Adenocarcinoma - isimila esibulalayo ezithinta nezicubu yezindlala zomzimba. Nokho, akubona bonke amacala umdlavuza pancreatic - umane uyisiko adenocarcinoma ezinjalo. Kwezinye izimo, isimila eba kusukela okuthiwa amaseli kwesinye isiqhingana esigcwele, ngakho ubhekwa njengesilwane esisengcupheni isimila neuroendocrine. Izimpawu nezinkomba ezibangela izinsolo umdlavuza incike indawo isimila, ubukhulu bawo uhlobo Indwangu, umfanekiso waso. Ngokuvamile, izimpawu umdlavuza pancreatic zihlanganisa ubuhlungu besisu, ubuhlungu emuva aphansi, futhi uma isimila licindezele imbobo Bile, jaundice. Ngaphezu kwalokho, kungenzeka kube abalulekile kwesisindo, ukulunywa, ukucindezeleka, acute umthambo thrombophlebitis (uphawu Trousseau sika), uphawu Courvoisier nabanye abaningi.

Esikhathini simo lomdlavuza esabulala abantu abaningi ukuzedlula umdlavuza pancreatic ngokuqiniseka ophethe i imbangela ohloniphekile wesine ehamba phambili yokufa kwabesilisa nabesifazane, kukholelwa ukuthi ibangelwa mayelana 6% wabo bonke ukubulawa umdlavuza. Cishe eliyizingxenye ezintathu omdlavuza pancreatic ukuthuthukisa ekhanda noma entanyeni umdlavuza, 15 kuya ku-20 amaphesenti izimila ekuthuthukiseni emzimbeni indlala ngqo, kanti amaphesenti angu-eminye 5 kuya 10 umsila wayo avele.

Wokwelapha isifo somdlavuza pancreatic kunzima ngokwanele, ngakho indlela ekutholweni kwale isimila kusaqalwa kakhulu, umsebenzi onzima kakhulu. Ngaphezu kwalokho, ngokusho izibalo, ngaphezu kwesigamu zonke iziguli ngesikhathi uphethwe "umdlavuza pancreatic" abathwali babe izimila metastatic, futhi amaphesenti angu-26 we lesion laligujwa e lesifunda zamanzi. Ukusinda isihlobo iziguli ngonyaka wokuqala ngemva uphethwe, "umdlavuza pancreatic" singamaphesenti angu-26 kuphela. Nokho, efana izinga oneminyaka emihlanu kuyinto ngisho aphansi nje nje 6%.

Kufanele kuqashelwe ukuthi zonke izimila pancreatic kukhona adenocarcinomas 80% ductal epithelium. 2 kuphela amaphesenti izimila kwamanyikwe exocrine awayona ingozi.

amafomu Ngaphansi ezivamile pancreatic izinhlobo umdlavuza histological zihlanganisa izimila ezifana giant cell carcinoma, i yezindlala, i-squamous cell carcinoma, kuhlanganise mikroglandulyarnaya adenocarcinoma, carcinoma mucoid, cystadenocarcinoma, papillary carcinoma fibrosis cystadenocarcinoma acinar, atsinoznokletochnaya cystadenocarcinoma. Kakhulu akuvamile kwenzeka ukuthi isiguli athuthukile isimila pancreatic ezicutshini. Uhlobo oluvame kakhulu lomdlavuza lymphoma amanyikwe.

Ngokuvamile, Ukudlulela lokuqala Imiphumela umdlavuza pancreatic e lesifunda lymph node, isibindi bese kancane njalo ephashini. Ngaphezu kwalokho, ungakwazi ukhule ngqo isimila singene ezithweni, okuyinto zisekujuleni ku peritoneum eduze nesosredstvenno indlala, isb kuya esiswini, duodenum futhi ikholoni. Ngaphezu kwalokho, umdlavuza pancreatic kungase iyakhula peritoneally kunoma iyiphi indawo etholakala ngaphakathi komgodi ongaphakathi kwamathumbu. Ngenxa yalokho, zingase ukuthuthukisa ascites (isifo sokuvuvuka), futhi kuba uphawu kakhulu, ezimnyama ezimbi. umdlavuza pancreatic kungaba iyakhula isikhumba nokuthi iyobonakaliswa efomini ngamaqhubu ezibuhlungu. Kukho konke lokhu izimila enjalo alivamile metastases ukuze amathambo.