Konke mayelana pepsin enzyme

Lesi sihloko sigxile kakhulu okushisa amaprotheni esisemqoka okukhona esiswini zonke esincelisayo, kuhlanganise nabantu. ekuhlaziyeni pepsin enzyme, ulwazi mayelana isomers yayo, kuzoxoxwa ngakho futhi indima agents izinqubo of kokudla esiswini.

ukubukwa Jikelele

Okokuqala nje, ake sizwe ukuthi yini ekilasini enzyme zihlanganisa pepsin. Lokhu kuzovumela Ukukuqonda kahle isihloko ngokwaso.

I proteolytic enzyme pepsin iphathelene isigaba hydrolases kukhiqizwa futhi mucosa esiswini abangababi bemisebenzi yaso eyinhloko wokuqhekeka amaprotheni adluliselwe nge ukudla, ukuze peptides. Pepsin - enzyme uhlaba amaprotheni e isimo asidi. It kuveza eziphilayo ezincelisayo, ezihuquzelayo, abameleli besigaba of izinyoni nezinhlanzi eziningi.

enzyme Kwethulwa kungokwalabo amaprotheni yohlobo globular, has a isisindo yamangqamuzana mayelana 34500.-molecule uqobo imelelwa neketanga polypeptide siqukethe acid amathathu namashumi amane acid. Ngo ngezithako zawo iqukethe HPO3 futhi ezintathu disulfide uxhumano uhlamvu.

Pepsin kabanzi lisetshenziswe kunjalo yezokwelapha futhi cheesemaking. Laboratories isetshenziswa ukuze uthole isifundo eningiliziwe zezakhi amaprotheni, okungukuthi, oyinhloko wamaprotheni abalulekile ekudleni kwengxenye isakhiwo. Pepsin kuyinto inhibitor yemvelo - pepstatin.

A ezihlukahlukene enzyme

Pepsin has isoforms nambili. Umehluko phakathi zonke isomers zimi pepsin electrophoretic motor amakhono inaktivatsionnyh izimo, umsebenzi proteolytic. Isikhombi pepsin - CF 3. 4. 23. 1.

Le ndoda in juice esiswini iqukethe eziyisikhombisa izinhlobo pepsin, futhi abahlanu kuwo kukhona ngqo ihlukaniswe ngezikhundla eziningana:

1. Empeleni pepsin (A) has a umsebenzi esiphezulu ku-pH naphakathi 1.9, futhi nokwanda-6 inactivated.
2. Pepsin 2 (B) iyasebenza ngangokunokwenzeka medium pH = 2.1.
3. Uhlobo 3 kuboniswa ngezinga eliphakeme yomsebenzi at-pH = 2.4-2.8.
4. Uhlobo 5, eyaziwa nangokuthi gastriksin has ngezinga eliphakeme yomsebenzi at-pH = 2.8-3.4.
5. Uhlobo 7 ngesikhathi pH = 3.3-3.9 izinkomba has umsebenzi eliphakeme.

Okusho enzyme ukugaya

Pepsin Kukhululwa nezindlala esiswini yefomu ingasebenzi (pepsinogen), kodwa umsebenzi wona ngokwawo enzyme oyenza hydrochloric acid. Ngosizo lwawo, iyaqhubeka kwifomu asebenzayo. Imfuneko ngomsebenzi we pepsin enzyme kuba phambi isimo esidi, yingakho ukwedlulela pepsin ku duodenum nje leyo ndawo ilahlekelwa umsebenzi wayo, njengoba emathunjini imvelo ane-alikhali. Pepsin enzyme unendima ebalulekile ekuthuthukiseni ukugayeka kwalo lonke ikilasi ezincelisayo, futhi ikakhulukazi abantu. Le into ubola amaprotheni ukudla ezincane peptide amaketanga nama-amino acid.

Abesilisa nabesifazane asebeneminyaka ukukhiqiza lolu enzyme izinkomba kuhluke. In amadoda, ngoba emhlabeni amabili kuya amathathu amagremu pepsin ngehora, kuyilapho owesifazane - amabili kuya amathathu angaphansi. Amaseli oyinhloko, isizukulwane pepsin isikhala, ke isehlane ngesimo pepsinogen ngobugebengu. Ngemva cleavage we peptides nge ethile N-ekupheleni pepsinogen ingena ifomu asebenzayo. I kulethe e ukusabela zamakhemikhali izenzo hydrochloric acid. Pepsin peptidase futhi protease possesses izakhiwo futhi unesibopho amaprotheni disaggregation.

ibhizinisi Medical

Kwezokwelapha pepsin it is kabanzi njengendlela nomuthi yezifo ezithile ezihambisana ngenxa yokuntula ukukhiqizwa lokhu enzyme esiswini sesiguli. Khiphela rennet enzyme pepsin kusukela esiswini porcine nolwelwesi lwamafinyila. Umuthi itholakala ngendlela amaphilisi, amashashaza ukubola i admixture acidin noma izimpushana. Pepsin eyilungu kanti ezinye izidakamizwa kuhlanganiswe. Ingabe ATC ikhodi A09AA03. Izibonelo zokugula lapho pepsinosoderzhaschie imithi kadokotela isifo Menetrier sika.

Inyama yenkomo pepsin - a ...

Rennet enzyme pepsin yenkomo - yezindlela owaziwa futhi asetshenziswa njalo kunazo yalolu ketshezi. Wona-enzyme akhiqizwa esiswini wesine sethole. , Yakheke Umuthi lisetshenziswe ukukhiqizwa by enzyme ezimbili: pepsin futhi chymosin amanani ngokwemvelo ezilinganiselwe. Rennet kusetshenziswa ekukhiqizeni ushizi, futhi umsebenzi wayo oyinhloko - ubisi ihlule kwetinhlavu kanye iqhaza inqubo nokuvuthwa ushizi noshizi imikhiqizo.

Inyama yenkomo pepsin ukhululeka izisu izinkomo nokuhlaba womshini imikhiqizo ukudayiswa, udabula izigaba ezimbili ukuhlanzwa enzyme kusukela fat futhi ukungcola okuyizinto zingaxazululeki. Inqubo yokwenza sezinkomo pepsin sihamba izigaba eziningana: yokuyigqula, salting ukuphuma futhi Sublimation omiswe.

Okunye Izicelo

I pepsin enzyme ibizwa added lwalungabola. Futhi-ke kusetshenziswa ekukhiqizeni ushizi. Rennet pepsin ibhangqwe chymosin yakha enzyme efanayo esetshenziswa igoqe ubisi.

Egoqekayo inqubo obisi coagulation ukuyibiza, okungukuthi casein ukwakha gel ubisi isisekelo. Casein has a isimo othize isakhiwo, uyedwa peptide isibopho unesibopho uhlobo enzymatic of amaprotheni ekunqandeni. Inxanxathela nge pepsin futhi chymosin uqobo unesibopho break uxhumano uqobo futhi kuholela coagulation ubisi.

isiphetho

Kufinyeta, singasho ukuthi lokhu isithako ingenye enzyme ezibaluleke kakhulu ezihilelekile ukugaya ukudla esiswini ngabameli amakilasi amaningi izidalwa eziphilayo. Esikhathini ukukhiqizwa imithi kanye ketshezi ikakhulukazi umuthi, futhi yengezwe rennet ngoba ekukhiqizeni ubisi noshizi imikhiqizo.