I-thiosulfate ye-sodium. Isicelo nokuphikisana

I-antidote, esetshenziselwa uketshezi ngamanoni noma amanye amakhemikhali esindayo, inamagama amaningana afana: i-hyposulphite ye-sodium, i-sodium thiosulfate, i-hypo-sulfate ye-sodium. Kodwa igama elivame kakhulu lale mithi yi-sodium thiosulfate. Ukusetshenziswa kwayo kubangelwa ukuthi izidakamizwa zibiza kakhulu, kanye non-toxic. Ukuphumelela kokuphathwa koketshezi nge-arsenic, ithusi, ukuhola, i-mercury, i-bromine noma i-iodine usawoti iphumelele. Ngenxa yokuxhumana nabo, ama-sulfite akhiwa emzimbeni, okungeyona enobuthi, kanye nezinye izinto ezingekho ezinobuthi noma ezinobuthi obuphansi. Ikhiqizwa ngesimo se-powder nesisombululo se-30% ku-ampoules nge-5 ml, 10 ml no-50 ml.

Ngenxa yezakhiwo eziyingqayizivele ezisetshenziselwa (ngokuhambisana ne-nitrium nitrite) njenge-antidote ye-poisoning ngama-cyanide (ama-cyanides), okuholela ekusungulweni kwamakhemikhali ama-rhodanous angaphansi kwe-toxic. Indlela yokwehlisa ubuthi nge- prussic acid kanye nosawoti wayo isekelwe ekuguquleni kwe-cyanide kuya kwi-thiocyanate ion engeyona into enobuthi. Ngaphansi kwesenzo se-enzyme rhodonase, i-thiosulfate cyanide-seratransferase (ikhona ezinhlobonhlobo eziningi, kodwa ngaphezulu kwesibindi) iyenzeka. Umzimba ngokwawo unamandla okunciphisa i-cyanides ngosizo lwe-rhodonase, kodwa le nqubo ephuthumayo ingasheshiswa kuphela yi-thiyo-sulfate ye-sodium, okusetshenziswa ngayo eyenza ukwethulwa kwabanikeli be-sulfur abangenangqondo emzimbeni.

I-thiosulfate ye-sodium iwusizo ekutheni kunezimo eziningi zempilo ezihlukahlukene. Ngaphandle kokuxoshwa kwe-detoxification, i-anti-inflammatory, antiparasitic (antiscabolic) kanye nezakhiwo ezilahlayo ezichaza i-sodium thiosulfate nazo zingabizwa. Ukusetshenziswa kwalo kwaziwa ngokuphathwa kwama-scabi. Isidakamizwa sokwelashwa kweziguli ze-scabi sisetshenziswa phezulu: isisombululo se-60% se-sodium thiosulfate sigxiliwe ezindaweni ezithintekile zesikhumba semiphetho noma isiqu. Uma kumile, lezi zindawo zihambelana nesisombululo se-6% se-hydrochloric acid.

Ngokuvamile isisombululo se-sodium thiosulfate sisetshenziswe ngaphakathi, ngomlomo nangesikhumba. Ngokwemvelo, njengamanje isetshenziswa njenge-antidote yokwelashwa kwe-cyanide ubuthi nokuvimbela nokwelashwa komdlavuza. Faka ngokuvamile i-5-10 ml yesisombululo se-sodium thiosulfate, kanye ne-50 ml yesisombululo - ngezilonda zama-cyanide. Uma kwenzeka ukuxilisa i-cyanide, ukubambezeleka ekulawuleni i-antidote akufanele kuvunyelwe, ngoba umphumela obulalayo ngokushesha awukhipha . Ngakho-ke, iziguli zigcinwa ngokucophelela ezinsukwini ezimbili zokuqala ngenxa yokuthi kungenzeka ukuphindaphinda izimpawu ze-cyanide poisoning. Kulesi simo, i-thiosulfate ye-sodium isetshenziselwa ngokuphindaphindiwe ngomthamo wesigamu. Ibuye isetshenziswe njengendlela yokulondoloza imithi.

Okuhlangenwe nakho okuningi (iminyaka engaphezu kwekhulu) kuye kwaqoqwa ekusetshenzisweni okuphephile kwe-sodium thiosulfate njenge-agent yokwelashwa. Idatha ekusebenziseni kwakhe kwezokwelapha iye yabhalwa kusukela ngo-1895. Isibonelo, ukuthola ukwelashwa okuhlanganisiwe kwe-arthritis, izifo ezigulayo, i-neuralgia sekuyisikhathi eside yaziwa ngokuba yizidakamizwa eziphephile njenge-sodium thiosulfate. Ukusetshenziswa kwalo kuphumelela njenge-agent ephikisana nokucindezeleka, i-antiarrhythmic kanye ne-metabolic. I-Thiosulfate iyingqayizivele, iphendula nge-radicals yamahhala ukwakha i-sodium sulfate compound.

Ukuziphendulela kwemvelo kuyisici esiyinhloko esingahle sinciphise ekusebenziseni i-sodium thiosulfate.

Ukuqhathaniswa: ukukhulelwa, ukukhulelwa nokulahlwa. Ukusebenzisa ukwelashwa kwabesifazane abakhulelwe nabakhohlisayo kufanele kube kuphela uma kwenzeka eziphuthumayo. Njengoba izifundo zokuzala ezilwaneni ezine-sodium thiosulfate zingakaze zenziwe, aziwa ukuthi zingathinta yini ikhono lokuzala futhi zenze imiphumela emibi embryo.