Isidakamizwa 'Aminazine'. Imiyalo yokusetshenziswa

Isidakamizwa esithi "Aminazine" sisetshenziselwa ukwelashwa njengenye ye-antipsychotics esemqoka isikhathi eside. Ukusetshenziswa kwezidakamizwa ezinyangeni zokwelapha akubangeli ubuthongo. Into esebenzayo i-chlorpromazine.

Isidakamizwa esithi "Aminazine" imiyalelo yokusetshenziswa ibhekisela ekuthomeni kwe-phenothiazine. Umuthi une-sedatif (sedative) nemiphumela ye-antipsychotic. Ukusetshenziswa kwalesi sidakamizwa kuvumela ukwehlisa noma ukuqeda ukucabangela okuphelele kanye nokukhohlisa, ukunciphisa ukusabela okufisayo, ukukhathazeka, ukukhathazeka, umsebenzi wokuhamba (ukukhungatheka kwengqondo). Ukuthatha ukulinganisa okuphezulu kwesidakamizwa "Aminazine" (ukudlula ngokweqile) kungabangela ukugubha, ukucindezeleka, izifo ezingaphezu kwe-extrapyramidal. Isidakamizwa sikwazi futhi ukwandisa ukufihla (ukuvimba) kweprolactin.

Ukufanisa umuthi "Aminazine", imfundo yokusetshenziswa ibonisa antihistaminic yayo, i-alpha-adrenoblocking nomsebenzi obuthakathaka we-m-cholinoblocking. Isidakamizwa sikwazi ukwehlisa ukucindezelwa kwegazi.

Indlela yokwenza isisombululo esiyinhloko ihlotshaniswa nokuvinjelwa ezindaweni ezihlukahlukene zobuchopho be-dopamine receptors. Umphumela wokuphumula cishe usekelwe ekuvinjeni kuma-adrenoreceptors aphakathi.

Ukungena ngaphakathi, umuthi usheshe uthathelwe ohlelweni lokugaya. Ukuncintisana kwenziwa ngokuyinhloko ngemifino kanye nomchamo. Ukuphela kwengxenye yokuphila sekude kakhulu (kusukela emavikini amane nangaphezulu).

Izidakamizwa "imiyalelo ye-Aminazine" yokusetshenziswa iphakamisa izimo ze-hallucinatory-paranoid kanye ne-paranoid engapheliyo, ukukhathazeka kwengqondo ngemuva kwesi-schizophrenia (nge-catatonic, hebephrenic, i-hallucinatory-delusional syndrome).

Isidakamizwa siboniswa ngophuzo oludakayo, i- pathologies engelapheki eyinkimbinkimbi yethoni ye-muscle eyanda, ukunciphisa ubuhlungu, kuhlanganise, i-causalgia (ubuhlungu obuvuthayo) ngokuhambisana nemithi yobuhlungu.

Isidakamizwa sinqunywe ukuphazamiseka kokulala okuqhubekayo (kuhlangene nama-tranquilizers kanye namaphilisi okulala), ukuphazamiseka kwengqondo ngokumelene nesimo sokuphuza, ukuhlukunyezwa komuntu nokucindezeleka okudabukisayo ekucindezelweni kwengqondo yomuntu.

Isidakamizwa esithi "Aminazine" imiyalelo yokusebenzisa ivumela ukuqokwa kokuhlanza abesifazane abakhulelwe, isifo sikaMeniere, ukulimaza izidakamizwa. Isidakamizwa sisetshenziswe ku-anesthesiology. Ngaphezu kwalokho, imithi iboniswa njengendlela yokuvimbela nokwelashwa kokuhlanza ngokumelene nesizinda se-anti-antitumour agents, ne-radiation therapy.

Isimo sokudoba sinqunywa isiguli ngasinye ngabanye.

Ngokujwayelekile ukudla kwansuku zonke kwabadala akulona amagremu angaphezu kwengxenye nengxenye, uma kuvunyelwe ukuthatha okungaphezu kwama-300 mg. Kwabantwana, inani lemithi libekiwe ngesilinganiso se-milligram eyodwa kilogram yesisindo.

Ukuthatha imithi kungabangela ukusabela okubi kakhulu. Imiphumela emibi kakhulu engaba yi-dyspepsia, tachycardia, hypotension, isikhumba esomile.

Isidakamizwa esithi "Aminazine" siyaphikisana nokuhlukumezeka kobuchopho, i-coma, esigabeni esiphezulu se- bronchiectasis, i- thromboembolism, ukukhubazeka kwe-cardiac okuphazamisekile. Ungabeki umuthi we-myxedema, i-pathologies eqhubekayo ebuchosheni noma emgogodleni, ukuphazamiseka kwezinso, isibindi, i-hematopoiesis.

Imiyalo ekhethekile

Uma isiguli sinqunyelwe ukuthatha umuthi "u-Aminazine" (kumaphilisi noma emishajweni) ekhaya, emva kokusetshenziswa kunconywa ukuba uhlale endaweni enezingqimba okungenani amahora owodwa nengxenye. Ungenzi ukunyakaza okungazelelwe. Lokhu kubangelwa ikhono lomuthi wokuncipha kwengcindezi yegazi.

Isidakamizwa "Aminazine" asihloselwe ukusetshenziswa iziguli ngokuzimela.