Biseptol: yokusetshenziswa

Sulfa izidakamizwa "Biseptol" imfundo ozokwethulwa ngezansi, kuyinto ehlukile enhle nemithi abantu nge contraindications ukusetshenziswa yokugcina.

igama Commercial zomuthi - "Biseptol". Ukufundiswa kuhlanganisa isihloko international: "Co-trimoxazole." Umuthi luyinhlanganisela i elwa namagciwane ejenti uhlamvu, ehlanganisa e isilinganiso 5: 1 sulfamethoxazole futhi trimethoprim.

Sulfamethoxazole, e Isifaniso nge isakhiwo kokuba acid p-aminobenzoic (PABA), ibe nomphumela ongemuhle synthesis dihydrofolic acid kumaseli webhaktheriya, ekuvimbeleni kwema- PABA dihydrofolic acid engqamuzaneni. Trimethoprim Sulfamethoxazole oyenza isinyathelo, ekuvimbeleni sokubuyiselwa dihydrofolic acid amaprotheni obhekene umzimba nokukhiqizwa microbial amaseli uhlobo folic acid - tetrahydrofolic. Ngakho, ngo-ukusabela okungenhla izingxenye ezimbili ukungasebenzi kwenzeka kwetinhlavu-folic acid, okuyinto nezilwanyana ezincane ezidingekile Kuhlanganisa purine compounds, nezinhlobo obengeziwe acid nucleic (DNA ne-RNA). Ngenxa yalokho, ukwakheka amaprotheni siphazamisekile futhi ukufa amagciwane kwenzeka.

Ngesimo ukulungiselela "Biseptolum" - ukumiswa imfundo manual, ngaphezu izinto esebenzayo, ukhuluma izinto uphiko: makroglagola glitserilgidroksisitearat silicate, magnesium-aluminium, sodium carmellose, citric acid, metilparagidroksibenzonat, i-sodium ne-hydrogen phosphate, propilparagidroksibenzonat, sodium saccharinate, maltitol, iphunga strawberry, propylene glycol, amanzi ahlanzekile.

Ngesimo ukulungiselela "Biseptolum" - amaphilisi ukuqondisa ngesikhathi excipients zihlanganisa amazambane isitashi, talc, magnesium stearate, utshwala polyvinyl, aseptiny M P, propylene glycol.

Ngokulinganiswa ukulungiselela "Biseptol" imfundo ine izinkomba ezilandelayo:

Ukwelashwa kwezifo Lokudabuka ezithathelwanayo kanye ukuvuvukala, okuyinto zibangelwa nezilwanyana ezincane:

- izifo yaleli pheshana zokuphefumula;

- sinusitis, abezindaba otitis;

- ubuchopho ithumba, meningitis;

- izifo kohlelo genitourinary;

- isipatsholo;

- izifo yokusetshenziswa pheshana emathunjini;

- izifo ka kwezicubu ezithambile nesikhumba.

Libuye mayelana nokusetshenziswa kwezidakamizwa "Biseptol" inalolwazi ezilandelayo:

- 240 mg izikhathi 2 ngosuku izingane ezineminyaka engu-2-5;

- 480 mg izikhathi 2 ngosuku eyenzelwe izingane ezineminyaka engu eminyakeni 6-12;

- 960 mg 2 izikhathi ngosuku izingane sebeneminyaka engu-12 ubudala kanye nabantu abadala.

Umuthi has omnene side effects ezisebusweni ekunqanyulweni yokusetshenziswa kwawo.

Izimo ukusetshenziswa "Biseptol" imiyalelo ukulungiselela zimi kanje:

- iziyaluyalu ukusebenza kwesibindi;

- iziyaluyalu nemisebenzi yokusetshenziswa izinso;

- iziyaluyalu uhlelo hematopoietic;

- ebuthaka esimiso senhliziyo nemithambo yegazi;

- Ukushoda zikashukela-6-fofatdegidrogenazny;

- nokukhulelwa;

- yobudala ingane izinyanga 3;

- khona hypersensitivity kuya izingxenye zalo.

Uma isiguli sekutholakele ukuthi sine- namathansela kubangelwa streptococcus, injongo yale izidakamizwa ayiboniswa. Ukuze ugweme kristallurgii, futhi ngenxa yalokho, urolithiasis, kufanele uhlinzeke engayitholi okusezingeni eliphezulu uketshezi. Ngekusetjentiswa isikhathi eside lapho ludingeka ukulawula isimo igazi neuropathy.

ukwelashwa Ngesikhathi trimethoprim kwandisa imiphumela ejenti hypoglycemic - sulfonylureas.

Ukusetshenziswa ahlangene we isisu thiazide kungadala ukopha anda thrombocytopenia.

Umuthi kwandisa isinyathelo umsebenzi protivosudorzhnogo ka phenytoin futhi warfarin anticoagulant uhlamvu.

Akubalulekile ukusebenzisa izidakamizwa esebenzayo kanye tsiklosoporinom, isizathu ngenjongo okuyinto izinso ukufakelwa, kusukela isimo patsenta kungenzeka zimbi nakakhulu.

Endabeni izidakamizwa ukweqisa izidakamizwa kumele imiswe amahora ama-2 iphume esiswini, iziphuzo eziningi, bamba diurez babelwe calcium folinate.

Umuthi kuyingxenye uhlu imithombo, okuyizinto emithini ebalulekile futhi ebalulekile.