"Tenorik": ukubuyekezwa odokotela. Izibhebhe yokucindezeleka okwandayo

Ngempumelelo uma izidakamizwa ezinjalo, njengoba "Tenorik"? Buyekeza lokhu izidakamizwa angashiya ngamunye. Ngokusebenzisa wemiyalezo enjalo futhi kodokotela kanye neziguli kulula ukuba siphethe indlela nomuthi wathi, noma ebangela ohlangothini ukusabela ukuthi zibhekene nomsebenzi.

Kulesi sihloko thina wachaza ngokuningiliziwe izakhiwo kanye nezici "Tenorik" izidakamizwa. Buyekeza nesineke ukuthatha oda udokotela wakhe, uyophinde abe kancane.

Ukwakheka, ukuma, incazelo, emaphaketheni

Ukulungiselela "Tenorik" (100, 50 mg) is imakethwa njengoba ezimhlophe amaphilisi isiyingi nge shape biconvex kanye komugqa.

Isakhiwo saleli imithi iqukethe izithako ezimbili asebenzayo: chlorthalidone futhi atenolol. Futhi, lokhu ekwakhiweni iqukethe izingxenye ezingezelelweko ethulwa ngesimo corn isitashi, sodium lauryl sulfate, i-lactose, polyvinylpyrrolidone, talc, Silica, magnesium stearate futhi isopropanol.

Asinakusho ukuthi iphilisi "Tenorik" (ukubuyekeza ngalokhu thuluzi, ungabona ekupheleni isihloko) embozwe ifilimu enamathela ekhethekile. Siqukethe methylene chloride, isopropanol, talc, hypromellose, ama-titanium dioxide, macrogol namafutha Vaseline.

Zuza kubhekwe isidakamizwa kungaba ibhamuza amaphakethe noma imicu amaphilisi 28 noma 100.

Imithi Pharmaceutical Imikhiqizo

Yiziphi amaphilisi "Tenorik"? Yokusetshenziswa (izidakamizwa intengo akuyona eliphezulu kakhulu) ibika ukuthi le nhlanganisela ejenti antihypertensive, okuyinto wakwazi ukubangela nomphumela owaqhubeka isikhathi eside hypotensive.

Kusebenta zomuthi ngaphansi kokucubungula ukuba isenzo 2 izingxenye, noma kunalokho isisu (chlorthalidone) kanye beta1-adrenergic blocker (atenolol).

izakhiwo Key

Ngokuthi atenolol cardioselective beta1-blocker. Ikhono ukukhetha izinto incipha nge okwandisa Isikali zomuthi. Atenol awunalo ulwelwesi lwangaphakathi eliletha ukuthula nemiphumela sympathomimetic. Njengakwamanye beta-blocker, it has a imiphumela emibi inotropic futhi kakhulu siyehla kwenhliziyo.

Kepha chlorthalidone, kuba isisu (sulfonamide netiazidny). It sithuthukisa Ukukhetha izici eziningana ezinjengolwazi chlorine ne-sodium. Futhi le ngxenye kwandisa uketshezi we Bicarbonate, magnesium kanye potassium. Umgomo we wesenzo antihypertensive lihlotshaniswa sodium excretion.

Atenolol lihambisana isisu iphumelela kakhulu kunokuba wena ukusetshenziswa ngamunye ncenye ngokwehlukile.

Isenzo kubhekwe isidakamizwa inakekelwa usuku lonke (emva umthamo owodwa ngezilinganiso nsuku zonke).

I kinetics zomuthi

Ngoba lesi sidakamizwa "Tenorik" analogs, intengo zazo kukhonjisiwe ngezansi, kuyindlela kuhlanganiswe cabanga izakhiwo kinetic ngayinye izinto asebenzayo ngokwehlukile.

Atenolol is amuncwa 40-50% kusuka pheshana emathunjini. okuhlushwa wobuningi kufinyelelwe ngemva 4 amahora emva ukungenisa tablet. Ukuxhumana amaprotheni cishe 8-16%.

Atenolol is bangaveziwe elikhanyayo umzimba uboniswe isibindi. Mayelana 90% izinto ugxile excreted ingashintshiwe amahora 8-9. Le nkathi kungase kukhule ukuhluleka ezinzima kwezinso, kusukela ukususwa atenolol ezenziwa izinso.

Kepha chlorthalidone, kuba 60% ugxile kusukela pheshana emathunjini. Ubuningi plasma kufinyelelwe esiphezulu yayo ngemuva kwamahora angu-12. Ukuxhumana amaprotheni cishe 75%.

Chlorthalidone esaboniswa izinso kungakapheli amahora 50.

izinkomba

Kusukela kubhekwe izidakamizwa yokucindezeleka okwandayo kuyasiza kahle. Empeleni, umfutho wegazi ophakeme emithanjeni, futhi kuyinto enkulu, futhi mhlawumbe okubonisa kuphela ukusetshenziswa.

Izimo

Manje, niyazi, ukuthi iyini injongo angabelwa "Tenorik" amaphilisi (izinkomba salokhu imithi banikezwe ngenhla). Kodwa, ngeshwa, kukhona kubhekwa umuthi namaphesenti i uhlu umxhwele Izimo. It is hhayi Kunconywa ukuthatha nge:

• ukushaqeka cardiogenic;
• pheochromocytoma;
• bradycardia (waveza nesimo sokuquleka);
• iziyaluyalu ezinzima ayesekhona neuropathy;
• hypotension (Ukuthuthukela ezinzima);
• lactic umzimba;
• AV-ukuvinjelwa 1st futhi degree 3rd;
• Sss;
• isifuba somoya lesichubekako;
• ukuhluleka kwenhliziyo (kokubili oyingozi futhi ezingalapheki);
• sikashukela;
• angina vasospastic (angina Prinzmetal sika);
• sifo;
• Ukucinana kwemigudu yomoya emaphashini obstructive;
• ukusha kwesibindi kohlobo acute;
• kahle kungakhuphula izinga likashukela,
• ukwehluleka kwezinso ngefomu acute;
• ngaphansi kweminyaka eyi-18;
• myasthenia gravis;
• hypersensitivity kuya izithako imithi.

Indlela "Tenorik" nomfutho ophakeme wegazi?

iziguli Adult ngokuthatha izidakamizwa e medium Kunconywa umthamo mg 100. Umthamo kokuqala zomuthi kufanele kube mg 50 kanye ngosuku.

Njengoba for the asebekhulile, lesi sidakamizwa "Tenorik" abelwe i eziningi ngisho ezincane.

Iziguli ukusebenza kahle kwezinso efiselekayo ukunciphisa imvamisa ukuthatha amaphilisi.

Kufanele kuphawulwe ukuthi ngemva kokusebenzisa isikhathi eside zomuthi kokubuyekezwa, ukukhanselwa yayo liyadingeka ukuze afeze kancane kancane.

side effects

Reception "Tenorik" Tablets angase avuse okulandelayo ukusabela uhlangothi:

• bradycardia, kukhuphuke inhliziyo ukwehluleka, emikhawulweni abandayo, hypotension orthostatic, arrhythmia, AV-block, izimpawu claudication ngakanye, Raynaud Syndrome ;
• ukudideka, ukucobeka, ikhanda, ukuhhema, sengqondo acute, paresthesia, ukushintshashintsha kwemizwelo, isiyezi, ukukhathala, ukuqwasha, disorientation, angaboni kahle;
• nomlomo owomile, transaminases anda isibindi, izinkinga zesisu, hepatotoxicity nge cholestasis intrahepatic, pancreatitis, isicanucanu, ukuqunjelwa, sokuzincisha;
• leukopenia, purpura, thrombocytopenia, eosinophilia, agranulocytosis;
• Alopecia, psoriasiform ukusabela, izinyembezi, exacerbation psoriasis, photosensitivity, ukuqubuka;
• bronchospasm, hyperuricemia, hypokalemia, hyponatremia;
• kahle glucose ukubekezelelana, ukwanda isibalo amasosha omzimba antinuclear, ziyancipha potency.

Le miphumela emibi ezingavamile futhi umnene.

Inani analogue

amaphilisi Izindleko "Tenorik" kuyinto ruble 110-120. Abakwazi esikhundleni izidakamizwa ezifana "Atenol", "Dinorik" noma "Tenoret".

Uphenyo imithi "Tenorik"

Buyekeza ukusebenza kwaleli thuluzi kungashiya ngamunye. Ngokusho iziguli nodokotela, izinzuzo main of leli thuluzi yilezi:

• ukusebenza;
• eziphansi.

I yokuntula yalesi izidakamizwa zihlanganisa:

• amathuba nezinwele kanye nokuthuthukiswa ubuthakathaka (ukunakekelwa isikhathi eside);
• ematfuba okuvela nokuquleka.