Sikashukela steroid: izimbangela, izimpawu, ukwelashwa

sikashukela steroid - lena ngempela isifo esiyingozi, okuyinto uhlobo lwesifo sikashukela. elinye igama layo - secondary insulini sikashukela engaphansi yohlobo sokuqala. Izifo ubiza ukuba nobuhlobo obungathi sina nesiguli. Lolu hlobo lwesifo sikashukela kungenzeka ngokumelene ingemuva ukusetshenziswa isikhathi eside ngamalungiselelo athile hormone, ngakho-ke libizwa izidakamizwa sikashukela.

Ngubani ehlaselwe isifo?

sikashukela steroid ungomunye walabo izifo ukuthi abe nohlamvu vnepankreaticheskim. Okungukuthi, akahlotshaniswa nezinkinga emsebenzini kwamanyikwe. Iziguli ebonwe iziyaluyalu carbohydrate umzimba, kodwa esasetshenziswa glucocorticoids (hormone ekhiqizwa nezindlala adrenal) isikhathi eside, ingakha sikashukela steroid, okuyinto umnene.

Izenzo sifo iyanyamalala ngemuva umuntu uyayeka imithi hormone. amaphesenti ayisithupha iziguli ezinalesi sifo phakathi uhlobo sikashukela yesibili kuholela yokuthi abanaso kufanele ukuthuthela ukwelashwa nge-insulini. Ngaphezu kwalokho, ukusetshenziswa isifo sikashukela singenza uthuthuke njengomuntu inkinga izifo lapho umuntu sithuthukiswe ekukhiqizweni kwama-hormone adrenal, isib, hypercortisolism.

Yimiphi imithi kungase kubangele isifo sikashukela izidakamizwa?

Isizathu sikashukela steroid kungaba ukusetshenziswa eside imithi glucocorticoid, okuhlanganisa "Dexamethasone", "Prednisolone" futhi "Hydrocortisone". Le mithi zingabameleli eqeda ukuvuvukala ezisiza ikhambi isifuba somoya, i-rheumatoid arthritis, kanye ezinye izifo sokuhlasela kwamasosha omzimba, okuhlanganisa pemphigus, lupus erythematosus, futhi eczema. Futhi, le mithi asetshenziselwa nokwelapha izifo ezinkulu zezinzwa like multiple sclerosis.

Ngaphezu kwalokho, isifo sikashukela izidakamizwa kungenzeka ngenxa ukusetshenziswa kwama-hormone zokuvimbela inzalo amaphilisi, kanye ezinye isisu thiazide, okuyizinto isisu. Le mithi ihlanganisa "Dihlotiazid", "Hypothiazid", "Nefriks", "Navidreks".

Ezinye izimbangela ngaphezulu isifo

sikashukela steroid kungenzeka abantu nangemva izinso Ukufakelwa. yokwelapha anti-inflammatory ngemva isitho ukufakelwa zidinga ukusetshenziswa kwesikhathi eside corticosteroids ngemithamo ezinkulu, ngakho iziguli kufanele uphuze imithi impilo yonke ukucindezela amasosha omzimba. Nokho, isifo sikashukela steroid ingekho zonke iziguli ababenezikhathi kuhlinzwa ezinzima, kodwa okungenzeka iphezulu kakhulu ngenxa yokwamukela hormone kuka esimweni ekwelapheni nezinye izifo.

Uma umuntu isikhathi eside wasebenzisa ama wahlakulela izimpawu zesifo sikashukela, kubonisa ukuthi isiguli isengozini. Ukuze ugweme isifo sikashukela steroid, abantu okhuluphele kudingeka ukuba unciphise umzimba futhi ukushintsha indlela yabo yokuphila, njalo nokuvivinya umzimba ukukhanya. Uma kwenzeka uma umuntu beyizidlova sifo, it is nhlobo ukuthatha hormone esekelwe ayekutholile.

I ngokucacile lesi sifo

mellitus Imithi libhekene iqiniso ukuthi ihlanganisa zombili izinhlobo izimpawu sikashukela. Ekuqaleni corticosteroids isifo sibaningi uqale ngokonakalisa beta cell, asezindaweni kwamanyikwe. izimpawu ezinjalo ejwayelekile DM 1. Nokho, insulin amaseli beta usaqhubeka vrabatyvatsya. Ngemva kwesikhashana, ezingeni insulini uqala wehlise nezicubu babe ingazweli kule hormone. Lezi izimpawu nobuntu sikashukela 2. Ngokuhamba kwesikhathi, amaseli beta ziqala ukuyeka ukusebenza. Ngenxa yalokho, ukukhiqizwa insulin kumisiwe. Ngokufanayo ageleza kanye insulin evamile sikashukela engaphansi Uhlobo lokuqala.

symptomatology

Izimpawu zesifo sikashukela steroid ziyefana ezinye izinhlobo zesifo sikashukela. Man ehlupheka amandla ukuchama kaningi, ukoma kwakhe futhi umuzwa zokukhathala livela ngokushesha okukhulu. Lezi izimpawu ngokuvamile omnene ebonakaliswa iziguli, ngakho akuvamile ziwulalelisise. Ngokungafani uhlobo 1 iziguli ngaphandle okusheshayo kwesisindo. Hhayi njalo odokotela kungaba ukuxilonga sikashukela izidakamizwa ngisho nangemva isiguli ukuhlolwa igazi. ezingeni eliphakeme kunawo wonke umchamo kanye kashukela ivelakancane. Ngaphezu kwalokho, acetone izibalo asemaceleni ukuhlaziya isiguli futhi zenzeka ezimweni ezingajwayelekile.

Indlela ukuze alulame lapho insulini ekhiqizwa

Lapho umzimba womuntu eyeka ukukhiqizwa insulin, le sikashukela steroid efana uhlobo lokuqala LED, nakuba sinezici yomzuzwana (izicubu insulin). Lokhu sikashukela iphathwa iyafana CD 2. Yiqiniso, konke kuncike kulokho abahluphayo umzimba isiguli uyahlabeka. Uma isiguli enenkinga ukhuluphele, kodwa uyaqhubeka ukukhiqiza insulini, kufanele unamathele ukudla udle izidakamizwa ushukela-ukunciphisa, njengokuthi "thiazolidinediones" noma "Glucophage".

Lapho kwamanyikwe isibe sibi ukusebenza, kutuswa ukuba bafake insulin, esiza ukunciphisa umthwalo emzimbeni. Uma beta-amaseli kungukuthi atrophied ngokugcwele okwamanje ke emva kwesikhashana umsebenzi amanyikwe kuza emuva evamile. Ukuze inkinga efanayo, odokotela linqume iziguli kanye ongaphakeme-carbohydrate ekudleni. Iziguli musa unezinkinga isisindo okweqile, ube nenamba Ukudla 9. Ukuze kulabo abaphethwe ukugcwala, odokotela batusa inombolo Ukudla 8.

Izici ukwelashwa lapho insulin hhayi kukhiqizwa

ukuphathwa kwama-steroid sikashukela incike insulini ekhiqizwa amanyikwe noma cha. Uma le hormone ayisaxhunyanisiwe ekhiqizwa emzimbeni wesiguli, iqondiswa ngesimo imijovo. Ukwelashwa ukuba siphumelele, isiguli kufanele ufunde indlela ukunikeza imijovo ye-insulin. Ubuningi ushukela egazini kumele njalo ukugadwa. ukwelashwa sikashukela izidakamizwa kuyindlela efanayo LED 1. Kodwa abafileyo beta amaseli engasakwazi ukubuyisela.

izimo Non-standard

Kukhona ezinye izimo zomuntu ngamunye ukwelashwa kwama-steroid sikashukela, isibonelo, isifuba somoya ezinzima noma emva kokuhlinzwa of kwezitho kwezinso. Ezimweni ezinjalo, ukwelashwa i-hormone, nakuba isiguli nokuthuthukisa sikashukela. amazinga kashukela kufanele kugcinwe ngesisekelo kwamanyikwe isebenza kahle kanjani. Ngaphezu kwalokho, ochwepheshe acabangele ukuzwela kwezicubu insulin. Kulezi zimo, iziguli babelwa hormone anaboliticheskie, okuyizinto usekelo olungeziwe umzimba, kanye nebhalansi isenzo glucocorticoids.

engcupheni

Umuntu has ethile hormone adrenal ezingeni okuyinto washintsha ngezindlela ezingafani. Kodwa akubona bonke abantu abathatha glucocorticoids basengozini yokuba nesifo sikashukela izidakamizwa. Corticosteroids kuthinte ukusebenza kwamanyikwe, ukunciphisa umphumela isenzo insulini. Ukuze alondoloze lokuhlushwa evamile ushukela egazini, amanyikwe kumele zibhekane imithwalo emikhulu. Uma isiguli uzwakalise izimpawu zesifo sikashukela steroid, kusho ukuthi izicubu baba ingazweli insulin, nensimbi kunzima ukubhekana imithwalo yabo yemfanelo.

Ingozi yokuba nesifo sikashukela izidakamizwa kwandisa uma umuntu enenkinga ye isisindo okweqile, isebenzisa ama ebulilini noma isikhathi eside. Njengoba izimpawu isifo akuzona ngokushesha, abadala noma labo abakhuluphele, kumele bahlolwe yamafomu esicashile sikashukela ngaphambi kokuqala ukwelashwa hormone ukuthatha imithi ethile kungase kubangele ukuthuthukiswa izifo.