GGT - kuyini? GGT (ukuhlolwa igazi) lapho kwenziwe futhi lokho?

Ngo amaseli isibindi kwakhiwa Bile, okuyilona elidingekayo ukuze umuntu ukumuncwa amafutha kusukela ekudleni kanye zokuqaleka kwezidakamizwa ezithile. Inqubo ukwakha Bile okuqhubekayo, kodwa lingena emathunjini kuphela uma edla noma ngemva kwalo. Ezinye izindaba zika-isikhathi lilondolozwe gallbladder. Lolu cwaningo sizwele maqondana lo yokujama tsi of Bile is vivinyo GGT. Hlobo luni ukuhlaziywa, esinikela ngolwazi nendlela ukuthi kwenziwe? Yilokhu sizoxoxa ngani kulesi sihloko.

GGT: ulwazi olujwayelekile

Ngo amaseli isibindi, futhi leli pheshana biliary kuyinto-enzyme okungukuthi kulethe ukusabela ezithile kwamakhemikhali. Ibizwa ngokuthi GGT (gamma glutamyl transpeptidase) futhi equkethwe kuphela kumaseli e-ukwa olunceleka egazini. Njengoba sokuvuselela amaseli kuyinqubo evamile ngokuphelele, khona esincane igazi GGT eyamukelekayo. Nokho, lapho kubhujiswa nabaningi amaseli Kungenzeka ukukhulula semali le enzayimu, okungukuthi ye-alamu. Lesi simo sibonisa khona isibindi oyingozi noma biliary izifo ipheshana.

Ukubaluleka sokunquma GGT

Sifo GGT umsebenzi (ukuhlolwa igazi ukuze kutholakale izinga lokhu enzyme), kubaluleke kakhulu ukuhlonza izinqubo ezilandelayo:

• cholestasis (Bile stasis) ;
• cytolysis (cell ukubhujiswa);
• ukukhula isimila esibindini;
• izidakamizwa noma utshwala ukudakwa.

Kuwufanele ukunakekela okukhethekile ukugxila into yokugcina. Utshwala futhi abanye izidakamizwa kuthinte ukukhiqizwa GGT. Kusho ukuthini? Lokho inani enzyme kungase kwandise kakhulu ngisho nalapho engekho izifo zesibindi. Futhi kukhona lo mkhuba abantu ababusebenzisa kabi utshwala noma ukuthatha ezithile izidakamizwa (isibonelo, "paracetamol" noma "Phenobarbital"). Kule ndaba, uvivinye GGT ngokuvamile sisetshenziswa ekwelapheni ukuluthwa utshwala.

Ngaphezu kwalokho, izinga le enzyme igazi uzimisele ngendlela elandelayo:

• ukuqinisekisa izinsolo odla ipheshana biliary (ebukhoneni isimila pancreatic noma amatshe e-Amapayipi Bile);
• ekuxilongeni sclerosing cholangitis futhi ziphathwe yisifo sokuqina biliary (primary);
• sokunquma imbangela nesanda ane-alikhali phosphatase (isibindi noma ithambo zokugula zesifo);
• ukuqapha isimo nempumelelo ukwelapha isiguli amademeshe ine GGT anda.

GGT ungasho ngalokho iyona Lesi sifo siphatha kakhulu ezifweni kwesibindi kanye biliary ipheshana enzyme. ezingeni layo liphuma ngokushesha kunokuba phosphatase ane-alikhali, isibonelo. Yingakho kubaluleke kakhulu ikakhulukazi izifo ezithile lapho abanye zinkomba "okusalele emuva" noma zidinga ukuqinisekiswa.

Injongo sokuhlaziya

Kwezinye izimo, iziguli babelwe ukuhlaziywa kwamakhemikhali kwegazi (GGT), ubani futhi kanjani it is wachitha? Uchwepheshe ukuze kuxhunyanwe ngoba nezindaba ezihlobene-gamma-glutamyl kuyinto hepatologist. Kunezimo ezimbalwa lapho kubalulekile ukwazi amazinga igazi enzyme:

1. Ovivinyweni lokuqala ukuze kutholakale izinga lokhu enzyme kubalulekile ngesikhathi amasampula isibindi, asetshenziswa ukulinganisa imisebenzi umzimba.

2. Uma une isicanucanu, ukuhlanza, ubuthakathaka njalo, ubuhlungu besisu, isikhumba ukulunywa, sezinyawo siphungule noma ukuhwalala umchamo, jaundice.

3. Lapho kabi utshwala noma ukwelapha isiguli isifo sokusha kwesibindi oludakayo.

4. Phakathi ngihlolwa okwejwayelekile noma ukulungiselela ukuhlinzwa.

Ukuze isifundo kuthathwe igazi emithambo yegazi noma capillary. Ngo inqubo tourniquet futhi venipuncture ayinakuba umuzwa mnandi kakhulu ngalokho udokotela ngokuvamile uxwayisa kusengaphambili. Ngaphezu kwalokho, belungiselela sitholakele isiguli unolwazi mayelana eziningi imithetho ebalulekile. Ngakho, amahora ayishumi nambili phambi ukuhlaziywa kuyadingeka yeka ukudla, futhi isigamu sehora ngaphambi ke - ungabhemi, ugweme ukucindezeleka ngokomzimba noma ngokomzwelo. Lokhu kuzokwenza uthole idatha elungile.

Imiphumela cwaningo kanye nemithelela yabo

Ngokusho imiphumela yokuhlola kuyabonakala ukuthi ukubaluleka GGT anda noma evamile. Enye alinikwa, ngoba egazini futhi zingase zingatholakali kuwo wonke ama-enzyme (ekuqaleni butholakala kuphela amaseli), nakuba lokhu kwenzeka akuvamile. Incazelo GGT (level yayo) imi kanje:

• Abesifazane inkomba amagugu bavela 0 kufika ku 32-38 U / l .;
• ngoba amadoda lesi sibalo ephakeme - 0 kuya 50-55 U / L ..

The ephakeme ezingeni of olunesisindo esikhudlwana lwaluba ezilimele Bile Amapayipi noma isibindi. Ake sibheke izizathu ezijwayeleke kakhulu ekukhuliseni izinga lokhu enzyme.

Izimbangela GGT isigqugquzeli

Uma umphumela uphenyo lwembula amazinga aphakeme le enzayimu, sikwazi ukukhuluma ngeziphambeko kusukela kuyinsakavukela. GGT bandisa inkonzo lingaphathelaniswa ne iziyaluyalu ezilandelayo:

• zonke izinhlobo isibindi ipheshana biliary - jaundice obstructive, izibazi, amatshe noma isimila e uvule imbobo Bile, umdlavuza isisu noma inhloko kwamanyikwe;
• isibindi sibe sesomile - izicubu evamile isibindi esikhundleni isibanda, kanjalo i- lo msebenzi isitho;
• umdlavuza noma isibindi metastases, isibindi lapho beshintsha bekhuluma izimila nezinye izitho;
• ukusha kwesibindi kohlobo B (kokubili oyingozi futhi ezingalapheki), okufaka utshwala;
• mononucleosis samafayela;
• umonakalo sokuhlasela kwamasosha omzimba kuya Amapayipi Bile okuholela eyinhloko isifo sokusha biliary noma sclerosing cholangitis;
• ukuvuvukala acute kwamanyikwe;
• metastases esibindini ngenxa yomdlavuza webele, wendlala, iphaphu;
• esingamahlalakhona senhliziyo ebuthaka futhi isilethikusebenza (nge ukuzibandakanya yesibili kwesibindi);
• i-hyperthyroidism kanye nesifo sikashukela.

Njengoba ubona, izizathu ukhulisa GGT isethi. Ngandlela-thile, bonke ezihlobana ngayo isibindi. Ngaphezu kwalokho, ama-enzyme eziqukethwe kwamanyikwe, ubende, izinso, wendlala (siqala izinto eziningi ezincane). Ngakho-ke, lesi sifo kwazo lezi zitho futhi kungathinta egazini amazinga ayo. Nokho, ukwandisa non-ngqo lokuhlushwa gamma-glutamyl kuphela iziyaluyalu kwesibindi. Izizathu ukwehlisa GGT kungase kwehle umsebenzi yegilo futhi ziphathwe yisifo sokuqina decompensated.

isiphetho

Kulesi sihloko sabuka ezinjalo-enzyme ezibalulekile njengoba GGT. Kuyini futhi yini kunqunywa ezingeni layo, njengoba kwabikwa ku. Siye safunda, lokho kungenziwa ezihambisana njengoba kuboniswa izinguquko igazi okuhlushwa, futhi lapho wabelwa ukuhlaziywa GGT nokuthi zisetshenziswa kanjani. Sithemba ulwazi kwaba wusizo kuwe.