"Valium" - analogue. "Dialipon": ukulaya odokotela Izibuyekezo

disorder umzimba somzimba isifo ovamile kakhulu. Inani elikhulu of yizifo ezihlobene nokungabikho ukuthuthukiswa of umzimba syndrome. Omunye isifo ezinjalo kuba sikashukela. Therapy eziyisisekelo isimo isifo abasafufusa sihlose ukunciphisa iziyaluyalu umzimba kanye ngcono qualitative isimo sokusebenza isimiso sezinzwa. izidakamizwa kakhulu ngempumelelo esisetshenziselwa ukwelapha izifo ezinjalo buyisidakamizwa "Berlition" futhi-analog yayo "Dialipon".

Ake sicabangele indlela lokho izingxenye eziyinhloko le mithi - lipoic acid, ukusetshenziswa kwayo ezimweni ezahlukene.

izici pharmacodynamic

The main isithako kungokwalabo izidakamizwa "Berlition" analogs zomuthi, alpha-lipoic acid kuyinto coenzyme kwemiqondo cishe zonke emangqamuzaneni omzimba. Umsebenzi oyinhloko le enzayimu kuyinto oxidative decarboxylation alpha-keto acid, okuyinto kuholela indima yayo asebenzayo ekugcinweni ibhalansi yamandla esitokisini. Ngu bahlanganyele umzimba ukusabela amaseli lipoic acid ikhuthaza elilungile ukunciphisa amazinga plasma ushukela (ngokwandisa ukusetshenziswa energy of substrate), kanye ekuthuthukiseni glycogen zamagama e hepatocytes. Njengoba lokhu coenzyme uhlanganyela ngentshiseko ukusabela we tricarboxylic acid umjikelezo, ukuntula yayo (isib elihlobene ne amazinga anda ketone) kuholela ukwehla in ukushuba izinqubo ukuwohloka aerobic glucose.

Ngenxa ukufana kwemithi kanye amalungiselelo amavithamini B lipoic acid akuyona kuphela sikwazi ukunikeza imiphumela anti-ezinobuthi futhi anti-oxidant, kodwa futhi kuthinte cholesterol umzimba lipid umzimba kanye nethonya hepatoprotective. imiphumela kwakamuva ngenxa ikhono a nomuthi ukuthonya okuthiwa SH-amaqembu amaprotheni.

kwebalingisi kwemithi

Ngemva edonsa Lipoic acid sibhekana nezinguquko eziphawulekayo ngenxa umzimba hepatocytes eyinhloko. Izinguquko ku isakhiwo ngokuyinhloko ngenxa namachibi yamaketanga ecaleni kanye kumiswa conjugates. ukutholakala System kwemiphakathi ehlukene nesineke zihlukile, ngenxa izici ngamunye umzimba kanye nethonya lesi sifo. Excretion lipoic acid metabolites yayo yenziwa ngokuyinhloko izinso, kodwa futhi kancane izidakamizwa excreted ku Bile. Ingxenye-ukuphila oketshezini olungenambala lwegazi kuhluka imizuzu 10 kuya ku-20.

Lipoic acid: isicelo

Lipoic acid kuboniswa ukusetshenziswa e iziguli sikashukela ukuthuthukisa asondelene nawo nozwela eziqhubekayo polyneuropathy sikashukela. Kunobufakazi mayelana nokusebenza kwama-thioctic acid ekwelashweni eyinkimbinkimbi isifo sokuqina kwemithambo yegazi, yenhliziyo Umthambo isifo futhi uhlelo hepatobiliary. Umuthi futhi ngempumelelo ekwelapheni elinobuthi, esindayo zensimbi (ngenxa ikhono ukubuyisela SH-amaqembu).

Izimo

Ukuze lipoic acid "Valium" noma Analogue yalo ekwakhiweni ibika "Dialipon" imfundo manual ukuthi basuke contraindicated ku ukuzwela anda ukuze izingxenye, ukuhluleka acute inhliziyo noma zokuphefumula. Babuye banqatshelwe ukuthatha ukudakwa chronic kabi hemodynamics cerebral ngesikhathi ibele.

"Valium" futhi "Dialipon": yokusetshenziswa

Izidakamizwa iphathwa ngemithambo yegazi evela isitsha ngaphandle dilution ngaphambi. Umthamo wansuku zonke lezi izidakamizwa abadala kuyinto 600 mg. Dropper "Valium" noma "Dialipon" ukubeka uconsisele okungenani isigamu sehora. Yiqiniso efakazela kwelashwa amabili kuya amane amasonto. Uma kudingeka, uqhubeke ukuthatha izidakamizwa kungaba ngesimo amaphilisi e umthamo ofanayo.

zisetshenziselwa "Valium" Tablets abadala ngesilinganiso 25-50 mg kabili noma kathathu ngosuku, izingane bangakwazi ukunikeza umthamo 12 noma 24 mg.

side effects

Imiphumela engemihle ezenzeka isimiso sezinzwa futhi analyzers, ziyabonakala ngesimo umbono double, umuzwa kahle zokunambitha. Nge okungenzeka eliphansi okuvela nokuquleka kungenzeka. Lesi sakamuva kwenzeka ngesimo nokuquleka encane noma usuke ungekho ngohlobo.

Igazi uhlelo kungadala izilonda oluhambisana ngohlobo thrombocytopenic purpura, imicimbi thrombotic lihambe ngemithambo wemikhawulo aphansi.

komzimba nezinto izidakamizwa obonakala njengenhlangano ububomvu, eczema kusayithi umjovo. Kwangathi ukuthuthukisa komzimba nezinto ezingeni umzimba, beqhubeka ngokwezifiso uhlobo ukushaqeka anaphylactic.

On the yingxenye yalo lonke umzimba kunganciphisa ezingeni glucose in oketshezini olungenambala lwegazi, iziyaluyalu apharathasi vestibular, ikhanda kanye nesiyezi.

Iziguli ezithola umjovo wokuqala izidakamizwa, kufanele batjelwe ngaso ngalokho kungenzeka ukubukeka ubuhlungu compressive ekhanda inhliziyo ukuthi samorazreshayutsya futhi asidingi ukwelashwa eyengeziwe.

Ungacabangi ukuthi umenzi kanye igama incike ukuvama ohlangothini ukusabela. "Berlition" analogs zomuthi Kuyathokozisa abangela side effects kuncike izici umzimba kanye nezifo.

iziyalo ezikhethekile ngokuqondene ukusetshenziswa kwezidakamizwa

Ngenxa nokuntengantenga okusezingeni eliphezulu zomuthi lapho zihlatshwa yilanga, i-isitsha izidakamizwa Kunconywa ukuba amboze black impahla opaque ikhava noma. Emongweni ngokuhlukana tselosoobrazno ukusetshenziswa ekhethekile nesembozo ukukhanya-ukuze sivikeleke.

Uma sicabangela umphumela hypoglycemic ozayo emva izidakamizwa abaphathi, ukunakekelwa okukhethekile kufanele kukhokhelwe ukuqapha ezingeni glucose in oketshezini olungenambala lwegazi iziguli sikashukela.

Esikhathini ukulungiselela ukwelashwa "Dialipon" Kufanele uyeke utshwala, njengoba lokhu kungehlisa kusebenta zokwelapha zomuthi.

Kumele kukhunjulwe ukuthi izidakamizwa ixubana noshukela nensimbi ion, ngakho contraindicated ngokuhlanganisa-alpha lipoic acid ne solution, Ringer sika, glucose, fructose. Futhi, izidakamizwa ayikwazi ukusetshenziswa ngokuhlanganyela izidakamizwa equkethe magnesium ion nensimbi.

"Dialipon" alisetshenziswa ngesikhathi ibele kanye lactation. Njengoba kungekho idatha ku-ukuphumelela izidakamizwa ezinganeni ukusetshenziswa yokugcina is contraindicated.

Idatha umthelela isidakamizwa izinga yokusabela futhi ikhono lokuphatha akukho izindlela.

ekusebenzisaneni izidakamizwa

Lipoic acid sithuthukisa umphumela zokwelapha insulin nezidakamizwa hypoglycemic. Lokhu kumele kubhekwe iziguli sikashukela.

ukweqisa izidakamizwa

Izimpawu ukweqisa izidakamizwa ibandakanya ukucanuzela kwenhliziyo, isiyezi kanye ikhanda, ukuhlanza, ukuyaluza kuze ukuthuthukiswa nokuquleka generalized. Uma ekutholeni ebulilini nomuthi angagcina izimo ezifana ukushaqeka hypoglycemic, necrosis striated imisipha yohlaka, okusithiyayo we isimiso sezinzwa esiyinhloko futhi ukuphazamiseka ukusebenza kwezitho zangaphakathi kuze ukuthuthukiswa lezo zitho zomzimba eziningi.

Ukwelashwa ubuthi lingaze, esekelwe imithetho isimo sezokwelapha esiphuthumayo. Lingekho ikhambi ethize. Ukusebenza kahle izindlela zelashwe engakaze lawo.

Uphenyo odokotela

Ngenxa ukusebenza kahle eliphezulu zomuthi, odokotela batusa ukusetshenziswa, ikakhulukazi ekwelapheni izinkinga zesifo sikashukela. Ngakwelinye ihlangothi, iziguli ukuthatha "Valium", analogue zomuthi, kwakungekho umehluko okukhulu ngempumelelo phakathi izenzo ezimbili.

Kuye ukubaluleka margin kungaba eyehlukile kakhulu izidakamizwa yalolu hlobo. Ngokwesilinganiso, phakathi kuka-650 no-950 ruble kuwufanele izidakamizwa "Valium" (analogue). Inani kuncike umthamo (umthamo ephansi - esingaphansi izindleko), kanye nomakhi.

isiphetho

Ukulungiselela "Berlition" analogs ngokuthi "Dialipona" noma "Turbo Dialipona" yizidakamizwa ngempumelelo ukuze silwe izinkinga zesifo sikashukela ezigulini obudala. Ngenxa nokusebenza ngendlela okusezingeni eliphezulu oqabulayo acid-alpha-lipoic ingaphinda isetshenziswe ekwelapheni lingaze zokusetshenziswa kabi kotshwala.