Okubanzi-spectrum penicillins. Ampicillin. imfundo

Kuvalelwe ebhokisini nge imfundo izidakamizwa ampicillin neze isitshela indaba ukuvela kwalesi izidakamizwa kanye nenzuzo yayo. Ngo kwemithi yesimanje united eqenjini we-beta-lactam ngezilapha magciwane (betalaktamov) kanye cephalosporins, futhi penicillins. Izidakamizwa kuleli qembu zingamathuluzi ngempumelelo kakhulu-antibiotic yesimanje. Umsebenzi wabo amagciwane nomsebenzi omkhulu ngokumelene ngokuyinhloko amagciwane Gram-HIV, ikhono ngokushesha ukunikeza umphumela elwa namagciwane kanye nethonya elibusa amagciwane esigabeni ayanda, waba kuyancomeka odokotela emhlabeni wonke. Betalaktamy ngaphandle abe sinekhono elimangalisayo lokungawuzwa ukungena kwengqamuzana futhi kakade etholakala khona ngaphakathi Amagciwane abatelekile. Ukuphumelela inqubo yokwelapha okuthuthukiswa yokuthi izilokazane ezincane abakwazi ngokushesha zikwazi ukumelana naso kubo. Ngaphezu kwalokho, ngaleso beta-lactam imithi elwa namagciwane kukhona ubuthi iphansana, basuke ibekezelelwe kahle ngisho nokusebenzisa isikhathi eside ngesikhathi ebulilini.

penicillin akuzange kusize iqembu izidakamizwa ihlanganisa nokwelashwa ngamakhemikhali kanye ukusebenza kahle eliphezulu futhi selectivity yemiphumela imithi elwa nawo. Kuze kube manje, le mithi kungaba kufanele ngokuthi umuthi ephelele. Ngu yayo elwa namagciwane umphumela penicillins elilingana izinto physiologically abakhuthele, lesiniketwe umsebenzi mzimba, isibonelo into enjalo ingase ibe lysozyme.

Naphezu izakhiwo ezinhle nge-penicillin akuzange, pharmacologists eside ukhathazwa ezinye kokushiyeka kwabo. Lezi zihlanganisa kungenzeka sensitization - anda amathuba wokuthuthukisa komzimba. Futhi kunciphisa ukusebenza kahle izidakamizwa hatchability okusheshayo of penicillins kusukela umzimba ukusebenza ngesikhathi lapho division iseli microbial kwenzeka kuphela. Ukuze sibhekane nalezi neminye amaphutha wasiza ekudalweni kwazo semi zokwenziwa penicillins.

Kulesi iqembu penicillins, ekuphatheni izindawo nomuthi spectrum ezibanzi kuhlanganisa ampicillin. Imiyalelo zihlanganisa izinkomba for ukusetshenziswa ukwelashwa izidakamizwa inike pielita, salmonellosis, inyumoniya, glomerulonephritis, ukucinana kwemigudu yokuphefumula, sinusitis nezinye izifo eziningi.

zokwelapha ezihilela ukusetshenziswa a nomuthi amafomu ezinjalo, ampicillin trihydrate, sodium ampicillin futhi ampicillin ngqo. Imiyalelo libonisa ngokucacile ukuthi umthetho bese isilinganiso esithathwa esimweni ngasinye ukutheleleka udokotela. Linga lokhu izidakamizwa akufanele kube. Ngaphezu kwalokho, udokotela ikhetha indlela esifaneleka kunazo zonke yokuthola ampicillin izidakamizwa. Imijovo iphathwa ezimweni ezingajwayelekile. Ngokuvamile uphuzwe ngaphakathi.

Ukuma udaba - kungcono 0.25 igremu amaphilisi noma amaphilisi. Ungase futhi uthathe powder ampicillin. Ukumiswa umthamo ibalwa ngokuvumelana ebekiwe umthamo owodwa we ketshezi esebenzayo.

Ngaphandle ampicillin kuyinto crystalline a okucolekile emhlophe. Kunambitheka ezibabayo. Ngo amanzi, kabi encibilikayo, cishe akusho chaza chloroform noma ethanol, noma emoyeni. Ampicillin sodium usawoti kungenzeka ngesimo powder noma okusindayo ukungena nakwamanye amazwe elimhlophe noma kremovatam. Kalula oncibilikayo emanzini, ukuphuza utshwala ngokweqile. Liveza izindawo hygroscopic. trihydrate Ampicillin - crystalline ezimhlophe powder. Ngo amanzi, yahlakazeka ngo-ethanol, cishe kuba zingaxazululeki.

Alikukhuthazi ukusetshenziswa ampicillin imfundo ezimeni hypersensitivity kuya penicillins, mononucleosis ezithathelwanayo, yokwehluleka kwesibindi, wegazi, izingane kuze kube inyanga eyodwa. Izimo Okungenzeka izifo yaleli pheshana emathunjini.