Umuthi 'Proflosin ": Izimpendulo iziguli nodokotela. Medicine "Proflosin": ukusetshenziswa Ukwakheka, ukubuyekezwa

"Proflosin" - a ekwakhiweni okuhloswe ukuba sisetshenziswe ngoba izinkinga urinary, ezithinta ukuxhumana nge Hyperplasia Prostatic ingozi yemvelo. Lokhu ejenti kuyinto blocker-alpha-adrenergic.

Isithako asebenzayo - tamsulosin, into, ngokwenza entanyeni isinye, ekunciphiseni ithoni yayo, eziphumulele nomthelela imisipha abushelelezi. imiphumela enjalo emzimbeni ikuvumela ukususa izimpawu zesifo kanye ngokucasuka ulungisa ukugeleza umchamo. Ukwakheka kuhlanganisa izingxenye ezengeziwe ezithuthukisa umphumela ukusetshenziswa kwezidakamizwa. Cabangela nokuthi yini imithi "Proflosin". Isifundo, ukubuyekezwa kwesicelo yayo, nekusebenta okusesihlokweni esithi.

Lapho kukhona ubuhlungu uma uchama futhi kubonakala sengathi isinye akukaze kube nalutho, nokusakaza ibuthakathaka, udinga ukuvakashelwa ophuthumayo Urologist. Ngokuvamile, lezi zifo zidinga ukusetshenziswa "Proflosin" lisho ukuthini. Nobufakazi abonisa ukuthi ingasetshenziswa isidakamizwa kungaba, kungakhathaliseki esigabeni lapho lesi sifo.

Ukwakheka, isakhiwo

I nomuthi kukhishelwa ngesimo amaphilisi, igobolondo le-okuyinto ancibilikisa emathunjini. Gelatine amaphilisi, they possess isenzo isikhathi eside. Ngaphandle isithako esebenzayo lichaza ekwakheni samanje triethyl citrate, a copolymer ka methacrylic acid ETHYL acrylate, i-cellulose, talc.

Pharmacokinetics, izinkomba

Ngemva zokungenisa ingxenye esebenzayo ngesikhathi esifushane ugxile cishe ngokuphelele pheshana emathunjini. Le nqubo ahlahlele emva kokudla ukuphuza, ezimweni ezinjalo kuba nzima kancane.

Ngenxa yalokho we eyamukelayo kusho ne-ejenti asebenzayo isamba 0.4 mg, okuhambelana umthamo owodwa, emakamu esiphezulu isakhi esiyinhloko ezitholakala igazi ngemuva kwamahora 6.

Uphenyo "Proflosine" wabonisa kanjani ukuthi unobuhlobo obuhle igazi eligciniwe - 99%. Ukulungiswa libhekene ukusatshalaliswa azinakwa - 0.2 l / kg. Umzimba kwenzeka esibindini, lo msebenzi wenziwa kancane, emva kusebenta kwaso, metabolites akhiwa. Ingxenye enkulu izidakamizwa ayishintshi ezakheke bese ufaka ekusakazeni igazi njengoba yayinjalo.

isithako futhi into okubangelwa ukucutshungulwa kwayo, kukhona okuphumayo ikakhulukazi umchamo, nge ingxenye encane ukulungiselela (9%) kungenziwa excreted angashintshiwe. Uma izidakamizwa waphasiswa emva kokudla, nenxenye ukuphila ikhiqizwa amahora ayishumi, uma elisetshenziswa njalo - emahoreni angu-13.

Ukwamukelwa kusho "Proflosin" Izibuyekezo uvumele odokotela kanye neziguli kanye dizuricheskih ukwephulwa ezenzeka ngokumelene isizinda Hyperplasia we wendlala (uhlamvu ingozi).

Izimo

Imithi contraindicated nge hypersensitivity kuya izingxenye zalo. Lokhu kusho ukuphathwa akunconyelwe hypotension orthostatic, ngisho emlandweni. Musa thatha izidakamizwa ebukhoneni hypotension, ukwehluleka ezinzima isibindi okwenzeka. Uma kwelashwa lifakwa esigulini okungamahlala kwezinso esingamahlalakhona amafomu lapho CS lingaphansi kuka-10 ml / imiz, kudinga ukuzithiba ngokucophelela kudokotela.

Ukusebenzisa izidakamizwa, ukukhethwa umthamo

"Proflosin" kobufakazi nesineke, umsebenzisi Kunconywa ukuthatha kanye ngosuku. Kusho kumele isetshenziswe lapho isidlo sokuqala. Omunye capsule kufanele kugwinywe ngaphandle kokuphazamisa ubuqotho bayo. Udinga ukugeza okuhle phansi imithi. I division zibe izingxenye capsule ungase uphazamise ngesilinganiso ukumuncwa isithako esebenzayo. Inkambo yokwelashwa ayifakiwe, ukuphuza imithi njengoba kudingeka, isikhathi sokwelashwa akuyona esilinganiselwe.

side effects

Kungenzeka yokuphazamiseka pheshana emathunjini, isimiso sezinzwa. Kungaholela izitsha uhlelo, inhliziyo negazi zokuzala. Phakathi ukwelashwa kusho ukuthi izinguquko isikhumba nezicubu ngaphansi kwesikhumba.

Inhliziyo yomuntu wasemhlabeni ingase ihlupheka enkingeni nge ejaculation, ezimweni ezingajwayelekile kakhulu, iziguli ziba priapism. Mhlawumbe ziwohloke abalulekile impilo lapho kukhona ikhanda, isiyezi, ngezinye izikhathi umuntu esengene eduze nakwisyncope.

Ngemva kokuthola imali, "Proflosin" kobufakazi nesineke bathi ukubonakaliswa cutaneous kwenzeka angioedema, ukuthuthukisa isifuba isikhumba silume, ukuqubuka livela. Kodwa lokhu kwenzeka kakhulu kuyaqabukela. Abantu bangakuthola ahlupha uhudo kanye ukuqunjelwa. Kungenzeka ukuthi niyozenezelelwa ohlangothini imiphumela isicanucanu, ukuhlanza, hypotension (postural), tachycardia.

Ezimweni ezimbalwa kukhona ukuthuthukiswa ungumthombo ongumngcingo umfundi syndrome ngenxa ukuhlinzwa cataract, rhinitis, asthenia.

Ezimweni ukweqisa izidakamizwa aye alotshwa. Kodwa, kwakuthiwa, kukhona okungenzeka. Uma ukweqisa izidakamizwa angase wehlise blood pressure, kungadala tachycardia. Ukuze normalizing wegazi, kwenhliziyo kudingeka ukuba ulale. Iphathwe a hemodialysis nesineke yinto engenanjongo, kusukela asebenzayo nomuthi ingxenye eboshiwe kahle kakhulu plasma amaprotheni. Kudinga isenzo uzoyeka ukumuncwa zomuthi - lavage esiswini, ukusetshenziswa i laxative osmotic noma i-carbon isebenze.

Izixwayiso

Lapho kukhona izimpawu hypotension orthostatic, ezifana ubuthakathaka, isiyezi, noma isiguli ohlezi ibekwe, ukwenza manipulations kunesidingo.

Ngaphambi kokuqala ukwelashwa, phakathi kwesikhathi lapho ohlela ukusebenzisa izidakamizwa isicelo "Proflosin", ukubunjwa, isithakazelo sangempela isiguli kwasekuqaleni, kodwa imiyalelo ezikhethekile ukusetshenziswa kwaso, futhi, libanakekele nokusiza hhayi ukulimaza impilo yakho nakakhulu. Kuqale ukwelapha, kubalulekile ukuba qiniseka ukuthi azikho uthi isiguli, okuyinto efana izimpawu of wendlala lesion - ingozi Hyperplasia Prostatic.

Ngaphambi ukwelashwa, kanye nokuqaliswa kwalo kufanele njalo kokwenza luhlolo digital rectal, uma kunesidingo - ukusetshenziswa PSA.

nomuthi khansela futhi ayisekho kabusha iqondiswa Ekuthuthukiseni angioedema. Phambi esweni futhi eyohlinzwa ukuze uyisuse ukwamukela "Proflosina" kungaholela sifo ka umfundi emincane. Ukuze ususe lowo mphumela, udokotela ohlinzayo Kumele wenze ukulungiselela ekhethekile preoperative, lo msebenzi futhi kwenziwe ngendlela efanele.

Lapho ekwelapheni "Proflosin" kusho iziguli izilinganiso ukuncoma ngokucophelela ukushayela izimoto futhi ukuhlanganyela emisebenzini ukuthi kungaba ezisongela ukuphila ngaleso lokuhlushwa ephansi, ukugeleza ngesilinganiso lengqondo ukusabela njengoba isiyezi ngezinye izikhathi ivela.

izidakamizwa ekuhlanganyeleni

Ngenxa imithi "Teoffillin" "Nifedipine", "Enalapril", "Atenol" ukuxhumana okungaxhunyiwe nge tamsulosin.

With ukusetshenziswa ngesikhathi esisodwa izidakamizwa nge "Cimetidine" nokwanda ezingeni lomcebo asebenzayo tamsulosin egazini. "Warfarin" "Diclofenac" ukukhuthaza ngaphezulu excretion okusheshayo kusukela tamsulosin umzimba. Lapho ngokuhlanganisa izidakamizwa "Proflosin" nezidakamizwa efanayo kungehlisa nemingcele blood pressure.

Lapho kuhlangene "Furosemide" ukwehla lokuhlushwa isithako esebenzayo zomuthi, Nokho, ukwandisa umthamo "Proflosina" kuleli cala akudingekile, ngoba ngemva wokwehla lokuhlushwa izidakamizwa esebenzayo kulondoloza umthamo evamile esanele yokwelapha izidakamizwa "Proflosin". Ukubuyekeza, umhlahlandlela, intengo, incazelo - konke lokhu kwaziswa kubalulekile lapho ekhetha ukuphathwa umuthi othize. Cabanga Izibuyekezo oluthunyelwe odokotela kanye abathengi niyolazi izindleko cishe zomuthi.

Izindleko izidakamizwa analogue

Ngaphambi kokusebenzisa amathuluzi "Proflosin" intengo, umhlahlandlela, ukubuyekezwa, ezimweni eziningi uhlolisisa yisiguli. Izindleko eyodwa iphakethe amaphilisi kuyinto ruble mayelana 400-500.

"Revokarin" futhi "Tulozin" kungenziwa ngihlukanisiwe nontanga. Kunezinye esikhundleni izidakamizwa ezifana "Fokusin" "Omnic".

Izibuyekezo

Ngemva kokufunda nokubuyekezwa umkhiqizo okwelapha, sikwazi ukukhuluma kahle yaso ephezulu. Isikhathi esiningi bathola "Proflosina" eyenziwa amadoda ngemva kweminyaka engu-50, lapho isifo wendlala eba. Iziguli eziningi weneliseka umphumela ukwelashwa, ezimweni eziningi, izinkinga urinary zinyamalale noma zenzeka kancane buhlungu indoda.

Ngezinye izikhathi imiphumela emibi kokubona izinkinga ukwakhiwa, tachycardia nokuncipha wegazi izinkomba. Ezinye iziguli 'Proflosin "akuzange kusize, ngakho kwadingeka anqume ekusebenzeni.

odokotela abaningi bakhetha ukuba aphathe lesi ukulungiselela, kuphela uma uqiniseka ukuthi izidingo zabo ngokunembile wahlangana yisiguli. Ochwepheshe bathi isidingo ukuhlinzwa kungagwenywa uma isiguli isebenzisa lesifanele (njalo ngesikhathi esithile) izidakamizwa "Proflosin". Ukubuyekeza, umhlahlandlela, analogs, isicelo, intengo manje seyaziwa kuwe, futhi, emva kokuthintana nodokotela wakho usungaqala ukwelashwa. Lo chwepheshe intando luhlolo futhi zibeka umthamo ezithile nomuthi, okumele ukusiza kuleli cala.