Yokusetshenziswa "Azimeda" mayelana nokubuyekezwa izidakamizwa

Abantu abaningi bayazama ukuze nje bagweme ukuphathwa-antibiotic ngenxa imiphumela engemihle leli qembu izidakamizwa. Nokho, kukhona izidakamizwa ukuthi kungenziwa ngokuthi ophephile - ke macrolides. Banezinhliziyo umthelela ubuncane omubi umzimba futhi ngaleyo ndlela bayakwazi ngokushesha ukuqeda amagciwane. "Azimed" - omunye abameleli alama-antibiotic. Lonke ulwazi oludingekayo mayelana ukuvuma kanye nokwelashwa izici nomuthi uqukethe imiyalelo ukusetshenziswa. "Azimed" zifika ziyizinhlobo eziningi, ingasetshenziswa ukuze bakwazi ukusiza iziguli bobudala obuhlukene.

incazelo Jikelele izindlela

Class kwamaphilisi macrolide, wanezela izindlela "Azimed". Lesi sidakamizwa yesimanje elwa namagciwane, oluqanjwe eziningi weenhlahla - "Kyivmedpreparat" futhi "Arterium" (Ukraine). Uma eqhathaniswa erythromycin, kusho ihlalisekile imvelo azibukhali ipheshana wokugaya ukudla, esinikela kuye nge bioavailability enkulu njalo iyehlisa ingozi nemiphumela engathandeki yalawo maphilisi.

"Azimed" lingena shí izicubu kanye izitho, lapho eqala buthelela. Lo mphumela kudala izidakamizwa lipophilic kakhulu. High izidakamizwa lokuhlushwa kokugqashuka kwalesi sifo iqhubeka amahora 36-50. Lokhu kwenza kube nokwenzeka ukunciphisa umthamo wansuku zonke kanye nokushintsha kokudla nokufakwa imvamisa imithi, okuyilona elisebenzayo futhi inzuzo enkulu. I-antibiotic has anhlobonhlobo imiphumela, njengoba kusho umbiko we yokusetshenziswa. "Azimed" wathatha zezilingo kudingekile emitholampilo lapho nephephe zomuthi okuye kungase kutholakale.

Yiziphi izithako?

Isenzo elwa namagciwane izidakamizwa inikeza into esebenzayo eziyisisekelo - Azithromycin. Lokhu azalide kokuba 15-membered lactone indandatho wabhanselwa nitrogen athomu nucleus. Ukwakheka kwamakhemikhali kanye nesakhiwo engqamuzaneni ukukhishwa azithromycin liphakathi namanye amalungu macrolides. Ziphephile imfuyo nomsebenzi mkhulu emagciwaneni igremu-negative: enflyuentsy coli (Afanasyeva, Pfeiffer), Moraxella catarrhalis, chlamydia trachomatis, Mycoplasma nenyumoniya.

Ukuzwela azithromycin umbukiso pertussis futhi idiphtheria, Helicobacter pylori, ureplazmu, spirochetes, anaerobes Listeria. Organisms amelana erythromycin, ngokuphelele ingazikhathaleli "Azimedu".

izingxenye engeziwe kufakwe Ukwakheka amakhemikhali izidakamizwa, ukuthuthukisa nomphumela oqabulayo. Lezi zihlanganisa i-calcium anhydrous hydrogenphosphate, magnesium stearate, corn isitashi, microcrystalline cellulose, ama-titanium dioxide, i-lactose, macrogol, triacetin, hypromellose, sodium lauryl sulfate.

izinhlobo macrolides

amaphilisi anamuhla macrolides zihlukaniswe yemvelo kanye semisynthetic. Isigaba sokuqala sihlanganisa erythromycin, leucomycin, oleandomycin, dzhozamitsi, spiramycin. Basuke eyatholakala kusukela nezilwanyana ezincane ethile. macrolides Yemvelo zinezikhathi kahle eliphezulu, kodwa lokhu ejenti pathogenic ngokwanele ngokushesha zikwazi ukumelana naso kubo.

Semi-zokwenziwa macrolides kukhona ithimba elisha lezifundiswa ezingu -ejenti elwa namagciwane. Sinenkosi anhlobonhlobo imiphumela, umsebenzi okusezingeni eliphezulu elwa namagciwane, kahle ikubekezelele umzimba. Umthelela oqabulayo zindlela inakekelwa isikhathi eside. Lolu hlobo kuhlanganisa azithromycin, clarithromycin, rokitamycin, fluritromitsin, roxithromycin. Isici ehlukile yikhono ukuthonya amagciwane igramu-HIV.

mshini wezenzo

Macrolide "Azimed" uzabalaza isenzo elwa namagciwane ngokuba nomthelela amaseli ribosome microbial uphinde ukubhidliza amaprotheni zamagama. ejenti ezithathelwanayo ayikwazi ukumelana ukuhlaselwa okunjalo futhi ishabalale. Isici ehlukile kuyinto omnene eqeda ukuvuvukala kanye immunomodulating isinyathelo, obonisa antibiotic. Ngokungafani nezinye elwa namagciwane, "Azimed" ingaqhubeka asebenzayo kwaphela izinsuku eziningana.

Ukukhishwa

Umuthi itholakala ifomu capsule (250 mg), amaphilisi (500 mg) kanye powder for ukumiswa (250 mg lomcebo esebenzayo). ifomu Pelletized senzelwe ekwelapheni abantu abadala nezingane enesisindo okungenani 25 kg. Njengoba yenziwe kusukela slurry powder has a emnandi elinuka ukunambitheka. Umthamo we isitsha - 20 noma 30 ml. Okufakiwe spoon wokulinganisa isipetu.

Izinkomba ukusetshenziswa

Macrolide antibiotic "Azimed" isetshenziswa ukwelapha ezihlukahlukene izimo zokucabanga okubangelwa isifo omsakazo ezithathelwanayo. Umuthi ngokuvamile ebekiwe iziguli ukungabekezelelani ukuba penicillins futhi cephalosporins. Ephambi kwezinduna yisifo esibangwa nezilwanyana ezincane nozwelo azithromycin, omunye onekhono uzokhokha ngabanye uhlelo idatha yokwelapha nomuthi.

Izinkomba ngoba "Azimeda" injongo zingezinye zezifo ezilandelayo:

• isifo engenhla ipheshana zokuphefumula (otitis, namathansela, pharyngitis, sinusitis, sinusitis);
• izifo we ephansi ipheshana zokuphefumula (pneumonia umphakathi aluthola, ukucinana kwemigudu yokuphefumula, exacerbation izifo ezingelapheki);
• idiphtheria, ukunqamulela kwekhibhodi
• isifo, izifo ezidluliselwa ngocansi (isipatsholo, i-chlamydia, chancroid, ugcunsula)
• urethritis, cervicitis;
• izifo zomlomo (periodontitis, periostitis);
• izinqubo ezithathelwanayo izicubu zomzimba ezithambile kanye isikhumba (impetigo, ezingamahlalakhona erythema migrans, pyoderma yesibili, beshiha, induna ezinzima);
• isilonda esiswini noma isilonda duodenal kubangelwa Helicobacter pylori.

Umuthi zinganikwa njengoba prophylaxis of ukukhwehlela whooping ngemva kokuthintana zomuntu onesifo. Imithi elwa namagciwane asetshenziselwa kulungiswe abathwali ukutheleleka meningococcal. Azithromycin isetshenziswa amazinyo for nokuvimbela ukuthuthukiswa endocarditis.

Khomba ukuthi "Azimed" izingane?

Ezimweni ezingane of nezifo zokuphefumula omsakazo ezithathelwanayo kuyizinto ezivamile. Ezinganeni izifo ezifana kungase kubangele ukuthuthukiswa sengozini yokuthola izifo. Ukuze ugweme imiphumela okungafunwa, odokotela antibiotic. ochwepheshe abaningi bakhetha ukusebenzisa for ekwelapheni macrolides, njengokuthi "Azimed" (ukumiswa noma amaphilisi).

Umuthi ikufakazele ngempumelelo ngenhlonipho kokubili Amagciwane extracellular futhi intracellular. Wamiswa njengenhlangano yokwelapha kokuqala, ngisho nezifo eziyinkimbinkimbi omsakazo virus. Lona ephephile anti-microbial, okuyinto cishe akukho imiphumela emibi futhi kahle ikubekezelele umzimba. Ngokuvamile, labo abanamakhono ebekiwe umthamo ubuncane izingane "Azimed" (100) zomuthi. Ezinganeni, lokhu lokuhlushwa izidakamizwa esebenzayo kubhekwa ephephile. Lokhu kusho ukuthi 5 ml ukumiswa siphelile iqukethe 100 mg azithromycin.

Indlela ukulungiselela ukumiswa?

Kubalulekile ukulandela imithetho ukusetshenziswa kwezidakamizwa. Kule ku ngempumelelo zayo zokwelapha kuncike ngokuqondile. Indlela ukuzalela "Azimed" ukuthola ukumiswa? Powder uku isitsha esuka lapho nomuthi iwukuba kuphekwe. Ukuze wenze lokhu, le isipetu ngiyolinganisa 11 ml amanzi selehlile abilisiwe futhi eyandisa isitsha. Ngemva kwalokho, ingxube kwaphumela kumele ayonyakaziswa kahle ukuthola mass homogeneous. Ngenxa yalokho-ke kufanele baphenduke 25 ml ukumiswa.

Umkhiqizo osuphelile kugcinwa izinsuku 5 kuphela, ngemva kwalokho wasebenzisa akuvumelekile. Ngaphambi umthamo ngamunye isitsha kufanele ayonyakaziswa. Kala lemali edingekile of imithi nge isipetu noma spoon. Ngemva kokuthola lezi "Azimeda" kufanele baphuze esincane okusamanzi (itiye, ujusi) ukuhlanza ngalo ingaphakathi ngomlomo kusuka slurry asele. Faka noma isipetu ngemva kokusebenzisa kufanele wageza ngamanzi agobhozayo yomiswa.

Isikali

Umthamo edingekayo zomuthi udokotela sinquma ngamunye. Ngokusho imiyalelo, pathologies esithathelanayo yasenhla nemithombo yasenzansi ipheshana zokuphefumula Kunconywa ukunikeza 10 mg isithako esisebenzayo kilogram of isisindo isiguli ngasinye. Lokho, isibonelo, ingane enesisindo 5 kg kumele inikezwe 2.5 ml ukumiswa.

Ngesimo amaphilisi (250 mg) kwezidakamizwa kuboniswa izingane enesisindo esingamakhilogremu angaphezu 25 kg. Abanye ochwepheshe batusa enikeza izidakamizwa ngesimo ukumiswa, uma ingane ukala engaphansi kuka-45 kg. Kulokhu kungenzeka ukuthola powder for temlomo ukumiswa "Azimed" 200 mg (ivolumu 30 ml). Uma isisindo sengane ezingaphezu kuka-45 kg umthamo engabelwe abadala. Isimiso ukwelashwa akhethiwe ngokubona uchwepheshe.

Kaningi reception umthamo nsuku zonke kweyeme Ihlahlubo khona izifo concomitant. iziguli Adult Livamise "Azimed" 500 mg. Lokhu Isikali ngokuvamile kuthathwe kanye ngosuku. Nokho pathologies, ezifweni ezithathelwana ngobulili, erythema migrans kanye isilonda ezingamahlalakhona esibangelwa Helicobacter pylori kuboniswa ukuthatha 1 g azithromycin ngesikhathi esisodwa ngosuku.

Kunini lapho kufanele ngithinte uyeke ukuthatha izidakamizwa?

Imithi is contraindicated uma ukungabekezelelani, hypersensitivity kuya macrolides noma izingxenye kwengoma. Ukwamukelwa izidakamizwa kungabangela eziyingozi. Futhi, "Azimed" ngesimo amaphilisi engamiswanga izingane zabo isisindo esingaphansi 25 kg futhi abesifazane ngesikhathi sokukhulelwa.

isithako akheka esibindini futhi excreted ku Bile. Ngakho-ke iziguli elinomlando babo kukhona ukwephulwa komthetho okubi kwesibindi, it is hhayi Kunconywa yokusebenzisa ama-antibiotic esekelwe azithromycin. Ephambi kwezinduna omnene kwezinso ukungasebenzi ushintsho umthamo imithi akudingekile, kodwa nokwelashwa kweziguli ezinjalo kufanele kwenziwe ngaphansi kokuqondisa ongoti. Ngokunakekela akunikeze imithi ezigulini esezikhulile.

Iziphi izinkinga zokwelashwa kungabangela "Azimed"?

Ama-antibiotic ezimweni eziningi asibekezeleleki kahle. Isizathu itholakala lokuthi ukuthi macrolides non-enobuthi nephephile phakathi izidakamizwa elwa namagciwane. Lokhu kuqinisekiswa kobufakazi nesineke, futhi yokusetshenziswa. "Azimed" azivamile kuphakamisa ukuthuthukiswa izigigaba ezingezinhle ukuthi avame esashiwo ipheshana wokugaya ukudla. Nohudo, ukucanuzela kwenhliziyo, ukuhlanza, ukubuyisa, ubuhlungu besisu - lezi ezinye zezimpawu ezivamile nemiphumela engemihle zomuthi emzimbeni.

ekuphathweni Okungalapheki ejenti elwa namagciwane ingase ukuthuthukisa ukusabela komzimba ngendlela ukuqubuka kwesikhumba, isifuba, ukulunywa. imiphumela Ukungaphathwa - Stevens-Johnson syndrome, ezinobuthi epidermal necrolysis - ezingajwayelekile kakhulu.

Kusukela ohlangothini imiphumela emibi kokuzwa (ikhala noma umsindo ezindlebeni, ukulahlekelwa kukuzwa) kukhona awushintsheki futhi zenzeka njalo. Isimiso sezinzwa esiyinhloko ingase futhi aphendule omubi yokwelapha ngemithi elwa namagciwane. Lokhu kubonakala izimpawu njengokuba nesiyezi, ukunambitheka ukuphendukezela, Ukudlikizela, somnolence, asthenia, ukuqwasha.

izigameko ezingezinhle ezavela uphinde ulandise jaundice cholestatic, necrotizing kwesibindi, ukushaqeka anaphylactic, umfutho ophakeme wegazi, ulaka, ukukhathazeka, thrombocytopenia. Ukumiswa noma "Azimed" amaphilisi uyeke ukusebenzisa ukuthuthukiswa amathuba okuba nemiphumela engemihle.

Izici isicelo

I-antibiotic kufanele kuhlanganiswe nokusetshenziswa nezinye izidakamizwa ezingase zithinte bioavailability nokusebenza ngempumelelo. ukwelashwa Ngesikhathi antacids wehlisa ijubane inqubo ukumuncwa zomuthi, lokho kuvimbela imiyalelo nesineke ukuze zisetshenziswe. "Azimed" Kumele kuthathwe okungenani amahora amabili ngemuva antacid.

Macrolide uyakwazi okwandisa emakamu serum ka anticoagulants, valproic acid, cyclosporin, theophylline, ergot amalungiselelo. digoxin umuntu ngemithi elwa namagciwane kungandisa bioavailability ngomlomo.

Ukuze ugweme imiphumela engadingeki yokwelapha ngemithi elwa namagciwane kuyadingeka ukuze ngokuqinile ulandele izincomo likadokotela, athobele umthamo lwemithi, hhayi ukwandisa umthamo. Kubalulekile ungalahlekelwa ngenkathi ngokuthatha izidakamizwa. Ngemithamo ezinkulu, "Azimed" (500 mg) ingasetshenziswa aphathe abantu abadala kuphela.

izidakamizwa elwa namagciwane Kunconywa kuthathwe ihora elilodwa ngaphambi kokudla noma amahora amabili ngemuva kokudla. Tablets wageza phansi amanani ezinkulu yamanzi, kanye nokumiswa. Ingane uvunyelwe ukwelapha isiphuzo (ukumiswa) juice noma itiye. Encwadini "Azimed" ifomu enjalo kugcinwa izinsuku ezingu-5 kule esiqandisini. Ngemva umthamo wokugcina kufanele ukuqeda isitsha slurry izinsalela.

Yini esikhundleni "Azimed"?

Intengo izidakamizwa kuyinto izindleko lisetudlwana yezinye ejenti elwa namagciwane. A ukulungiselela ngesimo amaphilisi kanye mg 500 umthamo in isiguli abiza ruble 160-200. Izindleko ukumiswa - ruble 140-170 (umthamo 100 mg / ml). Nokho, izidakamizwa ayitholakali kalula at Pharmacy kanye neziguli uzama ukuthola esikhundleni. Kufanele ngokushesha kucatshangelwe ezisiza kunodokotela kangcono akufanele bathembele kuleso lolodaba. Imithi elwa namagciwane ingase kuphela udokotela, ikhumbula isimo lesiguli, ubudala, comorbidities. "Azimed" ungayithola enye kuphela ngemva kokuthintana onguchwepheshe.

Analogue esekelwe azithromycin yasekuqaleni kusho lokhu okulandelayo:

1. "Ormaks".
2. "Sumamed".
3. "Zitroleks".
4. "Azivok".
5. "Asith".
6. "Hemomitsin".
7. "Azithromycin".
8. "Ziomitsin".
9. "Azitro".
10. "Azitral".
11. "Zomax."

Ngamunye imithi has izinkomba kanye netimphawu isicelo. Kahle ukulungiswa elwa namagciwane isinyathelo for ekwelapheni izifo ezithathelwanayo ingasenza kuphela ukhethe udokotela. Kunconywa ukuba kudlule ukuhlolwa laboratory ukuqinisekisa ubukhona lwegciwane amagciwane ukunquma ukuzwela layo lesi sidakamizwa "Azimed". Inani esikhundleni kuzoncika umthamo we ketshezi esebenzayo nomakhi.

"Sumamed" noma "Azimed"?

"Sumamed" - kungenye macrolide-antibiotic-azalide. Ngo lokuhlala encane it has a imakwe umphumela bacteriostatic. Inikeza microbial amaprotheni zamagama emangqamuzaneni enikeza kuphakamisa izinguquko izinqubo umzimba, kuvimbela ukukhiqizwa kabusha. Okwamanje, izidakamizwa elwa namagciwane ngokuvamile elibekelwe iziguli ezingane. "Sumamed" ubuye efanelekayo ekwelapheni iziguli esezikhulile.

"Sumamed" eyakhishwa inkampani Croatian eyenza imithi, njengoba kubonakala hhayi kuphela izinga kodwa futhi izindleko zomuthi. Ukuthengwa ejenti kungenzeka ngendlela amaphilisi (125 kanye 500 mg), gelatin amaphilisi (250 mg) kanye powder for ukumiswa setemlomo (100 kuya ku-200 mg). Analogue "Azimeda" Ubuye izakhiwo immunomodulatory, ezingahlobene umphumela wawo elwa namagciwane. Izazi zithi lokhu ikhono kungenxa yethonya izidakamizwa cyclooxygenase kanye kumiswa superoxide ion oxygen.

Bobabili izidakamizwa elwa namagciwane babe sakugcina nomthelela ongemuhle microflora emathunjini. Lokhu ugwema imiphumela engasi mihle kusukela pheshana emathunjini. Lapho kahle kokuthola imithi akusho avuse ukuthuthukiswa dysbiosis.

"Sumamed" ingasetshenziswa aphathe iziguli kulencane. tolerability Good sakugcina side effects niyenzé ithuluzi ethandwa kakhulu.

nobufakazi

Ukwelapha izifo eziningi ezinkulu ayikwazi wacabanga ngaphandle ama-antimicrobial. Kuphela ngalezi zindlela kungaba yokuvimbela ukusebenza kwamagciwane. Omunye abameleli isizukulwane lokugcina macrolides ephephile--antibiotic kuyinto "Azimed".

Uphenyo iziguli kanye nodokotela bathi ukwelashwa okuphumelelayo, abe nomphumela osheshayo zokwelapha kanye kunjalo akukho imiphumela emibi evela izibilini izinhlelo. Sebenzisa amaphilisi noma ukumiswa kufanele kube kuphela ngesiphakamiso uchwepheshe ngubani ngeke abale umthamo edingekayo isithako esebenzayo futhi isikhathi sokwelashwa. Ngemva ukwelashwa, i-ejenti elwa namagciwane, iziguli eziningi namanje batusa yokwelapha ukuvuselelwa kanye ukulungisa microflora emathunjini.