Umuthi 'Glidiab MV ": yokusetshenziswa, ngempela

Ukuze ukwelashwa nokunakekelwa Uhlobo lwesibili lwesifo sikashukela, lapho insulini eheha kwamangqamuzana emvelo esekelwe izindlela ezisetshenziswa gliclazide. Le into is a esuselwe sulfonylurea okuqondene isizukulwane sesibili.

izici Jikelele

Medicine "Glidiab MB 30" ubhekwa okulingana Russian of "Diabeton MV" izidakamizwa French. Iyatholakala Chemical-Pharmaceutical Isitshalo "Akrikhin" esifundeni Moscow.

I nomuthi iphathelene ejenti temlomo hypoglycemic ngefomu ithebhulethi kokuba ukukhululwa ukushintshwa. Faka umbala isakhiwo sabo emhlophe noma ukhilimu kungenzeka amabala amhlophe amaningi. Tablets zifane amasilinda flat kokuba chamfer.

Umthengi iphakheji iphakethe. Kungaqukatha 30 noma 60 amaphilisi ezipakishiwe ku ibhamuza amapuleti.

isakhiwo

Ngokungafani izidakamizwa "Diabeton CF" nge umthamo 0,060 g gliclazide, y nomuthi "Glidiab CF" inani ezifanayo isithako esebenzayo kule aphansi kabili, okuyinto 0,030 g

Ngu ngasebenzi tableting izithako zihlanganisa hydroxypropylmethylcellulose, aerosilovye amangqamuzana, magnesium stearate, microcrystalline cellulose.

Kukhona umuthi "Glidiab" nge ukukhululwa ezivamile we ketshezi esebenzayo. Isikali iphilisi ngalinye 0.08 g gliclazide.

kanjani

Njengoba unamathele nomuthi "Glidiab MV" imfundo manual lichaza isenzo gliclazide ukuthi yisiphi ukushukuma insulin uketshezi e β-amaseli, elise kwamanyikwe.

Ngaphansi kwethonya amaphilisi insulinosekretornaya umsebenzi kunyuke kwama-molecule e-glucose nezicubu neuropathy ziyazwela kakhulu i-hormone insulini.

Imisipha glycogen, ekubeni i-enzyme intracellular ubukisa ngekhono elingcono. Kukhona wokwehla isikhawu kusukela ekuqaleni ukusetshenziswa ukudla ukukhulula hormone. Kutholwa insulini uketshezi i-isiqongo ekuseni ukuthi ihlukile kwezinye kokumethemba gliclazide sulfonylurea, ebanjwa in esigabeni sesibili. Inciphisa postprandial glucose.

Ukuthuthukisa microcirculation kwenzeka ngokuhlanganisa adhesion platelet ne cell normalizing permeability semithambo, nokwehlisa ukuthuthukiswa atherosclerotic mikrotromboznyh izinqubo, ukusabela nokwehlisa nokonakala zemvelo amahlule. Kwehliswe ikhono lokuphendula yokwamukela izakhiwo e imithambo yegazi i-molecule ye-adrenaline.

Umuthi kungaba ijubane umlingisi retinopathy sikashukela esiteji, ku nonproliferative. Isikhathi eside ukuphathwa ejenti ngokuvumelana nemibandela ukulimala kwezinso sikashukela akha izingxenye obhekene zokuhlunga, kwenza kube nokwenzeka ukuba kakhulu ukunciphisa excretion wamaprotheni e umchamo.

Umuthi ayikhuphuki isisindo emzimbeni, kodwa kunalokho, kunciphe ngenxa nomthelela zisandakuqala insulini ukukhululwa. Akenzi avuse insulinemia owengeziwe.

Kungani ukusebenzisa

Odokotela batusa ukusetshenziswa kwezidakamizwa ushukela okusezingeni eliphezulu egazini besigaba sesibili. Ukwelashwa Kwenziwa awakuthinti mayelana nokudla kahle zokuvivinya umzimba ngokusesilinganisweni.

Ukuze nomuthi "Glidiab CF" izinkomba ezihambisana ne zokuvimbela ukuwohloka in iziyaluyalu sikashukela libhekene nephropathy, retinopathy, isilethikusebenza nonhlangothi.

Indlela yokusebenzisa

Izindlela nokushintsha kokudla nokufakwa kuyakhethwa isiguli ngayinye, unikezwa okubonakalisa isifo, lokuhlushwa glucose at esiswini esingenalutho futhi emva kwemizuzu 120 ngemva ukusetshenziswa ukudla.

Ukuze izidakamizwa "Glidiab MV" imfundo on isicelo esabela kokuqala umthamo zonke izinsuku we 0.03 g, okulingana iphilisi elilodwa. Lokhu okuhlushwa okuboniswe iziguli ezindala ngemva kweminyaka engu-65. Imithi esetshenziswa ngomlomo ithebhulethi eyodwa ekuseni lapho ibhulakufesi.

Uma kudingeka, umthamo luyanda njalo ngemva kwamasonto amabili. Inani eliphezulu elivunyelwe ngosuku olulodwa ukuthatha cishe 0,120 g, elihambisana amaphilisi 4.

I nomuthi "Glidiab CF" lalisetshenziswa esikhundleni igama elifanayo imithi ezivamile ukukhululwa, besebenzisa amaphilisi 1-4 ngosuku.

Its kuhlanganiswe izindlela hypoglycemic isinyathelo biguanide, alpha-glucosidase inhibitor yezinhlayiya insulini.

Ngo iziyaluyalu kwezinso ukusebenza uhlamvu ababuthakathaka noma okusesilinganisweni, lapho izinga creatinine imvume esingaphansi 0.080 amalitha ngomzuzu hhayi ukunciphisa nokushintsha kokudla nokufakwa.

Uma ungakwazi ukuthatha

Tablets "Glidiab MV" imfundo manual weluleka ukusebenzisa ifomu kuqala sikashukela nezifo sikashukela ngezinye ketones ephakeme emchamweni, paresis esiswini ngesikhathi hyperosmolar ikhoma sikashukela kanye precoma ngoba izinqubo zokuhlinza ezinkulu futhi bashise ukulimala, izinqubo kuhlasimulise uma kudingeka insulin ukwelashwa.

Izimo: iziyaluyalu okunzima isibindi noma izinso ukusebenza, wamathumbu isimiso, aguqule ukumuncwa ukudla, ukuthuthukiswa isimo hypoglycemic.

Awukwazi ukusebenzisa in iziguli imfiva, leukopenia, ukukhulelwa, ukuncelisa kanye nokungabekezelelani ngokweqile izithako, izidakamizwa.

Isexwayiso liyadingeka uma iqondiswa imithi, banakekelwe futhi Ukukhetha lwendlela okufanele isetshenziswe ngayo iziguli kufanele utshwala kanye ukushayisana indlala yegilo.

Izici yokwelashwa

Ngu izidakamizwa "Glidiab MV" afundiswe amaphuzu isidingo ukuhlanganisa ngayo-kilojoule amaningi yokudla ukudla ehlanganisa a carbohydrate okuqukethwe ongaphakeme. Kudinga zokuqapha njalo lokuhlushwa glucose esegazini ekuseni, ngaphambi nangemva kokudla.

Uma wahlinzwa noma decompensation yesimo sikashukela, mhlawumbe ukwethulwa insulini kusho.

Kube izixwayiso gipoglikemichekogo inqubo kwenzeka ukusetshenziswa ETHYL utshwala, a non-steroidal ejenti eqeda ukuvuvukala kanye ukungabikho amandla. Ukuphuza utshwala ngokweqile kungabangela disulfiramopodobnyh syndrome, nge ezidabukile ikhanda nesisu, isicanucanu nokuhlanza.

Kuyadingeka ukuba ulungise umthamo imithi ngesikhathi ukucindezeleka ngokomzimba noma ngokomzwelo futhi yokudla kungakabi yisikhathi.
Unozwela imiphumela izindlela abadala, iziguli ngokudla ongenakulinganisela noma simpofu, iziguli buthakathaka abaphethwe ukuntuleka uhlelo adrenal-pituitary.

Ezigabeni zokuqala kwesicelo zomuthi ukukhethwa umthamo, uma kukhona kungenzeka inkinga hypoglycemic, akudingekile ukwenza izenzo ezidinga kunakwa futhi ngokushesha lengqondo ukusabela.

ukusabela ezingezinhle

Esebenzisa "Glidiab MV" imfundo kuhlanganisa ulwazi ukwephulwa kwezitho endocrine ukuhluleka kuthebulethi mode, ukusetshenziswa kanye ukungondleki. Ngokuvamile, ukunciphisa glucose esegazini kubangela okuvela ubuhlungu ikhanda, ukukhathala, elambile, singenamandla, ukukhathazeka kokuba leso buthaka, ubudlova, ukugxilisa ingqondo, isimo sokucindezeleka. Futhi zikhona izinguquko okuqonda sibonwa, liqhaqhazela, thinta nasesiyaluyalwini convulsive, isiyezi, gipersomniyai, ukuphefumula engajulile, kwehle kwenhliziyo.

izitho zokugaya ukukhiqiza eziyimbangela yezinkinga ezizuzwa ngesimo malabsorption, isicanucanu, uhudo, ukungabi esesuthi anorexic, ukuphazamiseka isebenze amaseli isibindi, jaundice cholestatic, ukwandisa nekusebenta transaminase enzyme.

izinqubo engathandeki ohlelweni hematopoietic ezihlobene nokungawuvivinyi ngokwanele elithwala umoya-mpilo kanye nenombolo leukocyte platelet amaseli.

Umuthi kungabangela ukusabela kabi komzimba ngendlela ukulunywa, urticaria, makulo-papular ngamawala.

isingeniso ngokweqile

Okuhambisana indlela "Glidiab MV" bafundise ziyaxwayisa ngokumelene ukweqisa izidakamizwa, okuyinto kuboniswa ukwehla plasma glucose okuhlushwa. Uma imithi enamandla ngokweqile kungase ukuthuthukisa ikhoma hypoglycemic.

Ukuqeda umuntu unikezwa okutheni hydrocarbon ugxile kahle, isibonelo, isiqeshana ushukela. Lapho umuntu aquleke, uSathane wasungula ku vein amaphesenti 40 dextrose noma glucose isixazululo kanye bafake ku imisipha ye glucagon e isamba 1 mg. Uma isiguli niphapheme, ngaso ubizwa ngenkani ukudla hydrocarbon ugxile kahle ukugwema uphinda kuhlasela hypoglycemic.

Inhlanganisela imithi

Umsebenzi hypoglycemic we nomuthi "Glidiab CF 30 mg" bungathuthukiswa ngokwethula retarder parallel angiotensin ukuguqulela enzyme kanye Monoamine oxidase uhlobo yokwamukela zokwakheka blocker beta adrenozavisimyh futhi H2 gistaminozavisimyh cimetidine based, nezidakamizwa flukonazolovyh mikonazolovyh antifungal, non-steroidal anti-inflammatory ejenti Phenylbutazone, indomethacin, diclofenac.

Umthelela amaphilisi ukuchayeka anda usebenzisa clofibrate futhi bezafibrate, izidakamizwa ethionamide antitubercular kusukela iqembu salicylates, engaqondile compounds anticoagulant isakhiwo coumarin, Ama-anabolic steroid, cyclophosphamide, chloramphenicol, sulfonamides sibe nomthelela isikhathi eside.

Umuthi ngempumelelo kwehlisa ushukela oketshezini olungenambala lwegazi ngokusebenzisa blocker ka excretion ijabulise, ETHYL utshwala, acarbose, a biguanide, insulini.

Encishisiwe amaphilisi umphumela hypoglycemic kubangele barbiturates, nemithi based epinephrine, clonidine, terbutaline, ritodrine, salbutamol, ngisho phenytoin, inhibitor ka carbonic anhydrase enzyme uhlobo acetazolamide, isisu thiazide, amahomoni we indlala yegilo, izidakamizwa lithium-equkethe, amakhambi estrogen.

ETHYL utshwala-molecule bangathonya ukuvela inqubo gliclazide disulfiramopodobnyh.

Tablets ingxenye Active okubangela depolarization kwesikhathi futhi ventricular imisipha emangalisa esivimba amanzi lapho kuhlangene glycosides inhliziyo.

adrenoblokatornye Beta kusho klonidinovye, reserpine, guanetidinovye izidakamizwa kufihle kahle kungakhuphula izinga likashukela emtholampilo.

Ukubukwa iziguli

It is hhayi kuphela exhunywe nomuthi "Glidiab MV" imfundo manual. Izibuyekezo ukhuluma ngalokho iziguli cabanga ukuphumelela izidakamizwa. Leli thuluzi kusiza iziguli eziningi ukunciphisa okuhlushwa glucose ukuba amazinga evamile, futhi lihambisana Ukudla eshintsha isithombe zokuphila lesiguli.

Abantu bathi isici omuhle ithebhulethi ukusebenzisa kwayo elula ekuseni. Njengoba ngeke bakhumbule isidingo sokwelashwa emini.

On imithi "Glidiab MV" Izibuyekezo ungezwakala futhi uhlamvu engakhi ehambisana ukwehluleka leli thuluzi. Ngokuvamile lokhu kwenzeka lapho nokushintsha kokudla nokufakwa kahle uma inani elincane imithi kadokotela.