"Topiramate": yokusetshenziswa, migraine Okuyınqo, analogs

Ukungasebenzi kahle isimiso sezinzwa esilimaza ukusebenza wonke umzimba. Ngokwesibonelo, uma leso sifo efana yisithuthwane ngokulandelana kwawo, umuntu uthola ukukhubazeka esaphila. Ngokwemvelo, nale zokugula kufanele njalo ukulwa ukuze ukunciphisa izinga lokuhlasela kwesifo noma ukuvimbela ukubonakaliswa ukuhlaselwa. Ukulungiselela "topiramate", imiyalelo for ukusetshenziswa okuzokwenziwa ebhalwe lapha, nje ekwelapheni lesi egunjini lokuhlolwa kwezifo. Ngaphezu kwalokho, ingasetshenziswa ukulwa nezinye izifo. Lo mkhiqizo senzelwe ukusetshenziswa isikhathi eside.

incazelo Jikelele ukulungiselela kanye nokusungulwa

"Topiramate", imiyalelo for ukusetshenziswa okufanele kwakuchazisiswa isiguli, kuba ejenti antiepileptic esetshenziselwa impumuzo kanye nokuvinjelwa nokuquleka. Ezimweni eziningi izidakamizwa akhiqizwa ngendlela amaphilisi, ngaphakathi okuyinto kukhona powder emhlophe. Amaphilisi e ibhamuza amaphakethe of orange. Komunye wayo ingaqukatha 25 noma 10 mg isithako esisebenzayo - topiramate. Ngaphezu kwalokho, ngo-umkhiqizo engena dihydrate calcium hydrogen phosphate, magnesium stearate, isitashi, esindayo magnesium hydroxycarbonate. Ingqikithi Ungavimba isenzo pulses yesibili futhi kuvimbele nokuquleka.

Emva isiguli ukuthatha izidakamizwa, it is ngokushesha kakhulu ugxile esiswini namathumbu. Nge Amaprotheni egazi isithako main uboshelwe% 13-17 kuphela. Inombolo enkulu topiramate egazini waphawula emva kwemizuzu 120. Excretion izidakamizwa futhi metabolites yayo akhiqizwa ikakhulukazi umchamo. Isigamu-ukuphila amahora 21. Nakuba le nkathi zingandiswa uma izinkinga isibindi nezinso.

izinkomba

Uma Aye amiswa njengesigaba lesi sidakamizwa "Topiramate" imfundo manual ngalezi izinkomba uthi:

• Ukuquleka sokucasuka syndrome Lennox-Gastaut (njenge-ejenti asekelayo).
• I esinqunyiwe noma generalized nokuquleka tonic-clonic (monotherapy).
• Isifo sokuwa e izingane ezineminyaka engu-3 kanye nabantu abadala (isethi lokuqala).
• Ukuze kuvikelwe migraine kwabadala.
• Peripheral.
• ukucindezeleka Kwangemva Kwenhlekelele.
• Utshwala Syndrome.
• Manic-bacindezeleke ifomu sengqondo.
• onokuphazamiseka kwengqondo okuguquguqukayo.

Umuthi uyakwazi kujwayeleke kwemizwa. Njengoba ubona, "topiramate", yokusetshenziswa okuyinto njalo iphakheji umkhiqizo, has a uhla encane kwezicelo. Nokho, ngisho nakulezi zimo kubalulekile ukuthi iqaphele reception wakhe, njengoba lokhu imithi ibhekwa enamandla.

Izimo futhi kulinganiselwe ukusetshenziswa

Naphezu ukusebenza kwaleli thuluzi, it is hhayi Kunconywa kwezinye izimo. Phakathi Izimo kungathiwa elandelayo:

• yobudala Wezingane (eminyakeni engu-2). Umuthi sinamandla kakhulu umzimba wengane.
• Ukungabekezelelani kusho noma ezinye izingxenye zalo.
• Phakathi nokukhulelwa kanye lactation. The main isithako uyakwazi ukungena kuwo wonke izithiyo ngobisi lwebele.
• Ukuthambekela ukwakha ezinso.
• izinqubo ukuvuvukala Sinzima emzimbeni, pathologies ezinzima ezingamahlalakhona.

Ukwabela izidakamizwa "topiramate" migraine, udokotela udinga ukuba ikakhulukazi unake yalezo ziguli unezinkinga umsebenzi izinso kanye esibindini. Qalisa imoto evela endikimbeni kuleli cala okwehlisa, ngakho kungavela yezinkinga ezingalindelekile.

Iziphi izinkinga zokwelashwa kungenzeka?

Uma bamiswe izidakamizwa "topiramate", ukulaya inikeza ukubukeka ukusabela ezingezinhle:

• Isiyezi, ikhanda elibuhlungu, izinkinga umbono, inkulumo disorder, kukhuphuke ukwethuka. Kungase kubonakale lengqondo retardation, ukukhathala, ukungakwazi ukugxilisa ingqondo.
• Somnolence, lability ngokomzwelo, ukucindezeleka.
• Ezimweni ezingavamile, esifushane ukukhohlwa, ukudideka ukwazi, ukuphazamiseka ukunambitheka isasasa.
• Ukucanuzela kwenhliziyo nokuhlanza.
• Isibindi ukwehluleka.
• ukusha kwesibindi kohlobo Non-ezithathelwanayo.
• Ukuncipha komzimba.
• Ubuhlungu besisu.
• Chills.
• Ngezinye izikhathi kungase kwandise izinga lokushisa.
• Ukungabikho kokuya esikhathini, epistaxis, ukwehlisa wegazi leukocyte.
• Ezimweni ezingavamile kakhulu, ukuhhema kungenzeka.
• Encishisiwe acuity ezibukwayo, kanye nokwephula umsebenzi motor ubudala (they nyakazo angesabi). Nokho kungase kube yisishiso conjunctiva.
• Ukuvuvukala izinsini.
• Ukoma emlonyeni.
• Kwehliswe libido kubantu besilisa nakubantu besifazane. Lo mqeqeshi owake wapheka kungaba ukuhlasela ngisho nokuvusa induku.
• Kolwelwesi kanye isilonda esiswini.
• Isifo sohudo noma ukuqunjelwa.
• Halitosis.
• ubuhlungu bemisipha, ubuthakathaka.
• Noise noma enkeneneza ezindlebeni, futhi ngezinye izikhathi ukulahlekelwa kukuzwa.
• Ukwephula lokubhala nokufunda izingane.
• ukungabi namizwa emikhawulweni.
• Okwehlisa ukukhula izingane, buthaka of enamandla.
• komzimba ziyabonakala esikhumbeni: ukulunywa, ukuqubuka, izilonda.

Njengoba ubona, lesi sidakamizwa "Topiramate" migraine nakho ngokucophelela. esindayo Ikakhulukazi kuba izingane. Ngakho-ke, kumelwe ngokuqinile bathobele umthamo. Kulokhu, kokubili odokotela nabazali kufanele ngaso sonke isikhathi ukulandela isimo ingane.

Izici umthamo kanye nesicelo

Khomba kuboniswe ukuthi lo muthi kungaba udokotela. Self-uqale reception yayo akunakwenzeka, njengoba kukhona kungenzeka ukuwohloka. Ngaphezu kwalokho, izidakamizwa, udayiswa ngumnikezeli kadokotela.

Uma uke olubekiwe yokukhalaza "Topiramate" imfundo inikeza engayitholi yayo temlomo, kungakhathaliseki ukuthi uhlobo ukukhululwa. Phuza umuthi zinganikezwa ukudla, ikakhulukazi njengoba asithinti isinyathelo amaphilisi ingabe. Kuyinto efiselekayo isidakamizwa ngesikhathi esifanayo. Akufanele ukuhlafuna noma ukwambula amaphilisi, ngoba babe ukunambitheka ababayo. Ngaphezu kwalokho, izidakamizwa ukugaya ezingapheli zingayilimaza ukusebenza kwawo ngempumelelo.

Sebenzisa izinto kufanele kube ngale ndlela:

• Uma "topiramate" amaphilisi bayingxenye yokwelapha okuhlangene anticonvulsant, izinga yansuku zonke izidakamizwa kungaba isukela 200-400 mg. Lokhu kulinganisela ngokuvamile ihlukaniswe 2 imithamo. Kungcono ukuqala ukwelashwa nge amazinga okukhishwa ongaphakeme (25-50 mg), okuyinto ithathwe izinsuku ezinga-7 nsuku zonke. Ngaphezu kwalokho, umthamo liyakhula kancane kancane 25 noma 50 mg ngeviki noma amabili kuze kube ubuningi elikhulu, ugunyaza nomphumela omuhle. Thatha imithi kuleli cala, kabili ngosuku. Umkhawulo umthamo ukuthi iziguli omdala kungase kuthathe nsuku zonke, 1600 mg.
• Uma udokotela wakho ekunike ingane abaneminyaka engaphezu kuka-2 "topiramate", ukusetshenziswa kwalesi izidakamizwa ezivezwa isikimu ezilandelayo: ukuqala ukuphuza amaphilisi kudingeka umthamo 25 mg kabili ngelanga. Isamba ukulungiswa ngelanga kuyinto 5-9 mg esisindo / kg. Kungcono ukusebenzisa imithi kusihlwa, ngaphambi sokulala, ukuze kuncishiswe ingozi nemiphumela engathandeki yalawo maphilisi. Inkambo eyinhloko yokwelashwa yizinsuku ezingu-7. Uma kunesidingo, isilinganiso esithathwa Evikini elilodwa noma amabili ezanda 1-3 mg / kg. Ukwamukelwa sehlukaniswe izikhathi 2.
• Uma izidakamizwa isetshenziswa monotherapy, udokotela kufanele sibonise ukunakwa nesineke. Kumelwe ukulawula ukuvama zokubonisa nokuquleka emva esikhundleni anticonvulsant neminye imithi. Kufanele uqale ukuthatha inani lemali elincane 25 mg ngelanga kanye ngosuku. Ngaphezu kwalokho, imithombo yezokuzijabulisa ingadlulisela umthamo yanda, kodwa kwenziwa kancane kancane phezu amasonto 1-2.
• Uma isiguli awukwazi ukubekezelela ukwelashwa okunjalo, ngegalelo lako zingancishiswa, noma yokwelula isikhawu ukwandisa ukwamukelwa amazinga.

Ukuze kokuquleka kulinganisela ukhulise, kubalulekile ukuba afeze ukuqedwa zomuthi kancane kancane. Isikali Weekly izidakamizwa kuyehla mg 100.

ukweqisa izidakamizwa

Uma wabelwe esebenzisa "Topiramate" yokusetshenziswa (wena analogs Kamuva sizoxoxa) lapho ukuze sigweme imiphumela kubangelwa ngemithamo ngokweqile zomuthi. Nokho, zikhona izikhathi lapho isiguli ngasizathu simbe uthatha amaphilisi amaningi ngokungadingekile. Khona-ke zifike ukweqisa izidakamizwa.

It libhekene nesimo sokuquleka yanda, ukubukeka ukozela, umbono kahle, ukubambisana kanye ukucabanga. Imiphumela engemihle engase ngokweqile kungaba kukhulu. Ngokwemvelo, kulesi simo-ke kuyadingeka ukuba athathe izinyathelo esiphuthumayo ukusiza ukugwema semali into ku kwegazi.

Okokuqala, kufanele ushayele i-ambulense. Ngaphezu kwalokho, le nqubo wenziwa lavage esiswini. Futhi, isiguli kumelwe athathe izidakamizwa umswakama "Enterosgel" carbon isebenze. Uma isikhundla sinzima kakhulu, isiguli ngokushesha esibhedlela. Ukuze kokukhipha izidakamizwa egazini ngu inqubo hemodialysis osebenza.

Izici nokuxhumana neminye imithi

Uma udinga ukuthatha "Topiramate" imfundo manual (omqondofana kungaba nomphumela ofanayo emzimbeni) uthi akusiyo iyahambisana zonke imithi. Isibonelo, kungenziwa kuhlangene valproic acid "pentobarbital", "Carbamazepine". Le mithi zenzelwe ekwelapheni izifo sezinzwa. reception ahlangene kubhekwe akuphazamisi ingqondo ku-plasma yegazi. Nokho, umthamo "topiramate" zingancishiswa. Kunoma ikuphi, ukuqokwa le mithi ekwelapheni elihlangene, umthamo zonke izindlela ezidingekayo ukulungisa ngokufanelekile.

Uma udokotela wakho uye wanquma linqume imithi ethulwa ngokuhlanganyela "pioglitazone", kubalulekile ukuqapha isimo lesiguli sikashukela. Ngokuhlanganisa "Topiramate" nge "metformin" kungase konakalise umzimba carbohydrate emzimbeni. Co-nokuphathwa wathi izidakamizwa nge "acetazolamide" futhi analogue yayo kwandisa ingozi ezinso.

Cabanga nangendaba yokuthi ukuze ahlanze umzimba umuthi namaphesenti metabolites yayo ukuthatha izinsuku ezimbalwa. Ngo nabantu kahle umsebenzi kwezinso, kulokhu zingandiswa kabili. Kuyadingeka ukuba bazi, njengoba kubalulekile ukuba ulungise umthamo. Izinga imithi udokotela ibala ngamunye icala ngabanye.

Izixwayiso

Uma une ukusebenzisa "Topiramate" amaphilisi (yokusetshenziswa kuyinto idokhumenti main elawula izidakamizwa) kufanele esiphuza ngokuhambisana nemiyalelo ye udokotela ukuba khona. Nokho, kukhona ezinye iziqondiso ekhethekile akufanele ishalazelwe:

• Uma kwenzeka lokuhoxa abakwazi ukukwenza esithubeni nje. Iqiniso lokuthi kukhona kungenzeka ukuthi imvamisa futhi ukushuba nokuquleka ukwandisa. Ngakho-ke, ukunciphisa kwezinkambiso zomuthi kufanele kwenziwe kancane kancane.
• Omunye imiphumela emibi izidakamizwa kungenzeka sokuzincisha ukudla, okuholela eqinile Ukuwohloka umzimba ngenxa kwesisindo. Ukuze ugweme lokhu, sicela uxhumane okunomsoco. Ukudla kufanele kushintshwe ukuze umzimba uthola zonke amavithamini ezidingekayo namaminerali ukuze operation efanele.
• Phakathi ukwelashwa akufanele lidliwe izidakamizwa ezithinta ingqondo kanye notshwala.
• Medicine "topiramate" (imfundo, impendulo, kanye nokuba khona kontanga ulwazi kubaluleke kakhulu ukuze isiguli) inethonya elinamandla ku izinga yokusabela, ukuze ukushayela imoto noma besebenza ngemishini eziyinkimbinkimbi ngesikhatsi ukwelashwa akufanele kube.
• Tablets akufanele inikezwe izingane ezingaphansi kweminyaka engu-2 hletnego.
• Kufanele uqaphele kakhulu kulezo ziguli okukuyo inso ukwephulwa ukusebenza kanye isibindi.
• Uma ukhohlwa ukuthatha ithebhulethi ngokuqinile ngesikhathi, zama ukuphuza uma khumbula. Nokho, uma une kufika isikhathi sokuba yokwamukelwa olulandelayo, ngoba catch-up akufanele bathathe umthamo double. Kungcono bayaqhubeka ukuphuza imithi kuze kube uhlelo okhethiwe.
• ukwaziswa okunokwethenjelwa mayelana isenzo mutagenic zomuthi kwi umzimba womuntu awuwona ngempela. Nokho, ukutadisha izidakamizwa e amagundane sokucasuka ukubukeka izimila lwesinye. Nokho, lokhu kuye kwenzeka okweqa elivumeleke, futhi ezimweni ezingavamile.

izinyathelo zokuqapha

Uma uthatha le izidakamizwa "Topiramate" imfundo manual (ukubuyekezwa imithi Uzofunda kamuva) liphakamisa elinye izinyathelo zokuphepha ukuthi kumele ihlangabezane ukuze ugweme izindawo elivela kuzo ukusabela ezingezinhle:

• Uma isiguli isebenzisa umshini wezinso, ukulungiselela isenzo ngempumelelo zimise kwesigamu umthamo wansuku zonke ngaphambi inqubo uhlanzekile igazi futhi ngemva kwaso.
• Phakathi ukuhoxiswa izidakamizwa Kufanele andise baphuza uketshezi. Lokhu kuzovimbela sebethule ezinso.
• Uma kukhona sina kwesisindo, kungenzeka ukuba ulungise ukudla bese wengeza lwezakhamzimba ekhuthaza ukumuncwa kwezakhi.
• Undesirably kanye "topiramate" ukuthola izinto ezenza abantu sezinzwa uhlelo ukucindezeleka.

Njengoba ubona, lokhu izidakamizwa kuyingozi kakhulu, ngakho-ke akufanele self-medicate, ngoba ungenza izinto zibe zimbi nakakhulu.

Izici Isitoreji, analogs kanye nokubuyekeza

Uma ivezwa esebenzisa efanelekayo, ungacela mayelana analogs izidakamizwa ezifana "topiramate". "Topamax" yokusetshenziswa okuyinto kakhulu efana incazelo langaphambilini, ungomunye wabo. It has isithako efanayo esebenzayo. Kukhona neminye imithi analogue "Topsaver", "Toreal", "Maksitopir". esitshalweni ngokuzenzakalela, le mithi bengayi. Mhlawumbe ngeke ukunikeza nomphumela omuhle, ngoba ukuqanjwa kwawo ingehluka. Ngaphambi kokuba uqale ukuphuza imithi enikeziwe kufanele kudokotela. Ikakhulukazi ngaphandle kadokotela kwabo othile singenakwenzeka batawubhala.

Gcina izidakamizwa kumele kube endaweni emnyama lapho hhayi zingene ray kancane ukukhanya, umswakama. Ungafaki ketshezi kude ukushisa imithombo. Isiqinisekiso isikhathi sokusebenza kuyinto 2 iminyaka. Emva kwalesi sikhathi, umuthi kumele ilahlwe. Futhi lokhu kufanele kwenziwe ukuze kukho abakwazanga ukufinyelela izingane.

Njengoba for izibuyekezo, bahlukile. Iziguli uqaphele kahle eliphezulu zomuthi lilawulwa nokuquleka. Muhle kakhulu migraines. Nokho, i-ejenti has a izindleko kuqhathaniswa eliphezulu. Ngokwesibonelo, ngentengo eyodwa iphakethe kungaba ruble 600 nokuningi. Uma ilungile ukusebenzisa izidakamizwa, kuyasiza sifinyelele ukuthethelelwa eside. Nakuba zikhona nezinye imicabango yabantu. Ngokwesibonelo, kwezinye izimo, izingane ziye kahle inkumbulo nokunakwa, ukubambezeleka zentuthuko, bese kuba khona umuntu imithi kungasizi. Kukhona isimo Ukuwohloka nezinso.

Kufanele kuqashelwe ukuthi kwezinye izifunda zezwe imelelwa izidakamizwa itholakala ku kadokotela-free, kuncike lokungayikhokhi ezithile. Kodwa ngaphambi kokukuthenga ithuluzi, kumelwe kudokotela ubani oyakuninika imvume. Khumbula, self kubabangele eziyingozi. Sesihlole umphumela ekwakhiweni ezifana "topiramate", imiyalelo, ukubuyekezwa migraines nokuningi. Xhumana nodokotela futhi ube nempilo!