"Phenylbutazone" (amaphilisi): yokusetshenziswa, analogue, intengo kanye nokubuyekeza

Kusukela lokho futhi kumele uzisebenzise kanjani enqunyiwe imithi "Phenylbutazone" (amaphilisi)? Yokusetshenziswa, izinkomba, properties kanye izici izidakamizwa izokwethulwa kulesi sihloko.

Futhi lapho uzothola ulwazi mayelana kubiza malini, kusho izindlela izithako afakiwe ngezithako zawo (asebenzayo futhi asisebenzi), futhi uma yini imiphumela emibi.

Izithako futhi emaphaketheni imithi

Yiziphi izingxenye eziqukethwe izidakamizwa "Phenylbutazone"? Tablets zimumethe isithako ezifana Phenylbutazone. Futhi izidakamizwa zihlanganisa: amazambane isitashi, primelloza, magnesium stearate, sodium Bicarbonate, talc futhi Silica.

Izidakamizwa "Phenylbutazone" (amaphilisi) okuthengiswa ibhamuza amaphakethe, okuyinto ebiyelwe amakhadibhodi emaphaketheni.

izici Pharmacodynamic zomuthi

Bewazi yini ukuthi lena izidakamizwa ngokuthi "Phenylbutazone"? Izibuyekezo ochwepheshe ukubika ukuthi kuba non-steroidal anti-inflammatory ejenti esesikhundleni umphumela antipyretic kanye analgesic.

Ukuphumelela kule ejenti lihlotshaniswa ikhono layo kuthiye umsebenzi cyclooxygenase. Ngenxa umthelela onjalo siyehla synthesis prostaglandins.

nomuthi Okubukwe sithuthukisa reabsorption usawoti namanzi ku tubules kwezinso. Iphinde aqede ubuhlungu futhi kunciphisa ukuvuvukala, okuyinto ngokuvamile ehambisana nobutha ukuvuvukala.

owenza nomphumela oqabulayo "Phenylbutazone" izidakamizwa kanjani? Tablets ukunciphisa ubuhlungu bamalunga (ngesikhathi ezinyakazayo futhi uphumule), kanye zabo ziye zancipha ukuhamba noma ukwanda ububanzi motion.

isinyathelo eqeda ukuvuvukala yaleli ejenti ngokuyinhloko kuphakeme kunokuhlakanipha 'Amidopyrine "izidakamizwa ezifanayo.

Lapho nomuthi asebenzayo sifo kabili excretion urate emchamweni, futhi kunciphisa inani legazi.

Phawula futhi ukuthi lesi sidakamizwa "Phenylbutazone" (amaphilisi), yokusetshenziswa okuyinto linamathele emgodlweni amashashaza, kunciphisa ubuhlungu nokuvuvukala izimpawu lapho thrombophlebitis (nasezinkingeni ezilandela ngemva kokuhlinzwa emithanjeni hemorrhoidal).

izici Kinetic ekulungisweni

izidakamizwa "Phenylbutazone" (amaphilisi) lapho ugxile? Umhlahlandlela ibika ukuthi ukumuncwa okusezingeni eliphezulu zomuthi kusukela ipheshana emathunjini kwenzeka. bioavailability yayo imayelana 87-90% kanti esiphezulu plasma lokuhlushwa siyenzeka emva kwemizuzu 60-150 emva abaphathi.

Kusukela izidakamizwa igazi kancane kancane ludlulele izicubu kanye izitho, futhi lingena singene ingaphakathi ngokuhlanganyela kanye ngokusebenzisa kusivimbeli gazi ebuchosheni.

Umzimba lokhu ejenti esibindini. Nakuba ingxenye-ukuphila salo amahora 19-25. Ingabe okukhipha ngokusebenzisa izinso kanye nomuthi ngokusebenzisa ipheshana wokugaya ukudla.

Izimpawu ze-lozenges

Kwezinye izimo, libeke izidakamizwa "Phenylbutazone"? Tablets sibonakalise ngempumelelo ngokwabo ekwelapheni:

• ankylosing spondylitis;
• osteoarthritis;
• arthritis psoriatic ;
• i-lupus ne-rheumatoid arthritis,
• tenosynovitis futhi bursitis;
• sokuqaqamba kwamalunga gouty ;
• algodismenorei;
• ubuhlungu post-op;
• izinyo kanye bekhanda.

Futhi, lolu izidakamizwa isetshenziselwa ukudambisa ubuhlungu e neuralgia, sciatica, betshisa.

Izimo imithi kokuthola

Kungakanani is yethu kubhekwe umuthi? Kuyini wentengo? "Phenylbutazone" angathengwa ngasiphi esitolo izidakamizwa ngenjongo yokuthola imali ezingabizi kakhulu. Sizokwenza ukwethula ke ekupheleni isihloko.

Ingabe kukhona Izimo kule imithi? Ngokusho imiyalelo, umuthi kungenzeka ingasetshenziswa uma:

• opha pheshana emathunjini emlandweni;
• ukungabekezeleli acetylsalicylic acid;
• inhliziyo isigqi disorder;
• hypersensitivity kuya Phenylbutazone;
• umnkantsha ukucindezelwa;
• exacerbation of izilonda emathunjini bese peptic isilonda isifo ipheshana wokugaya ukudla;
• decompensated ukuhluleka kwenhliziyo;
• hepatic futhi ukwehluleka kwezinso;
• hyperkalemia;
• ngaphansi kweminyaka eyi-12;
• sokukhulelwa, ikakhulukazi trimesters wokuqala nowesithathu;
• uma uthatha neminye imithi aqukethe Phenylbutazone.

Yokusetshenziswa "Phenylbutazone" izidakamizwa

Ngokusho imfundo ukulungiselela "Phenylbutazone" kuthathwe ngomlomo ngemva kokudla 150 mg kane ngosuku. Umthamo eliphakeme eyodwa izidakamizwa 200 mg, kanye nsuku zonke - 600.

Isikhathi yokwelapha nale ejenti kuncike isifo nokugasela ngamandla isimo lesiguli. Ulapha elilingana 400-600 mg ngelanga, uyakwazi kuncishiswe inani umchamo sikashukela insipidus.

Intsha engu-12 of iphilisi "Phenylbutazone" ukhombe 75 mg kathathu ngosuku. Ukuvimbela ukusebenza ecasulayo yalesi izidakamizwa mucosa isisu kutuswa ukuba baphuze ubisi olufudumele.

Ephambi kwezinduna izifo articular umphumela nomuthi banezelwa ekuphathweni kanyekanye "prednisolone" (ukumnika, i.v.).

Kufanele kuphawulwe ukuthi ukwandisa zokwelapha umphumela "Phenylbutazone" amaphilisi sihlanganise ngamafutha "Phenylbutazone".

ukusabela ezingezinhle ngemva ukungenisa amaphilisi

Reception "Phenylbutazone" amaphilisi kungabangela ukusabela elandelayo letindzala:

• ukucanuzela kwenhliziyo, ubuhlungu besisu, dyspepsia;
• ukuhlanza, stomatitis aphthous, isilungulela;
• ulceration we ulwelwesi lwamafinyila we wokugaya ukudla pheshana, uhudo, enkeneneza ezindlebeni;

• ukopha emathunjini;
• gingival ukopha hemorrhoids;
• umfutho wegazi ophakeme;
• ukwephula kwesibindi;
• ikhanda, kwegazi, ukucindezeleka, leukopenia, isiyezi;
• ukozela, agranulocytosis, injabulo, thrombocytopenia.

Imiphumela engemihle egazini futhi zidinga ukuqedwa ukuphathwa izidakamizwa kudokotela onguchwepheshe.

Sodium kanye nokugcinwa amanzi emzimbeni ezihambisana ngokungenisa "Phenylbutazone" ngokuphawulekayo olimaza isimo iziguli nomfutho wegazi ophezulu kanye CHF. Lokhu okwamanje futhi ludinga ukulungisa ukwelashwa.

izidakamizwa Okufanayo futhi intengo

"Phenylbutazone" amaphilisi (izingcezu 20) angathengwa ruble 40-70.

Ngokuqondene Isifaniso, njengoba zisebenzisa izindlela ezilandelayo: "Phenylbutazone-OBL", "Artrizin", "Phenylbutazone", "Butalidon".

Uphenyo iziguli imithi

Manje ngoba sewuyazi ukuthi lokho izidakamizwa "Phenylbutazone" intengo. Izibhebhe azibizi, kodwa ngokuphathelene ukubuyekezwa, base izokwethulwa ngezansi.

Ukuhlaziya indlela iziguli kulo muthi, singaphetha kahle ukuthi ngempumelelo kuzibonakalisa zonke izinhlungu ngokuhlanganyela kanye kwemisipha. Kodwa, ngaphezu okubuyayo, iziguli kaningi ngidele kuye, kanye nemiyalezo engemihle. Ngokusho kwabo, "Phenylbutazone" amaphilisi bavame ukubanga yezinkinga we emathunjini ipheshana igazi emizimbeni. Kule ndaba, odokotela abaningi batusa ukuba bangayeki kokuthatha lesi imithi, futhi esikhundleni salo imoto ephephile.