"Neostigmine" (isibhamu)

"Neostigmine" (imijovo) buyisidakamizwa zokwenziwa, main izidakamizwa esebenzayo okuyinto uba neostigmine methylsulfate.

Lokhu ukulungiselela has a anticholinesterase umsebenzi evelele, futhi ngenxa yalokho emva ukusetshenziswa kwalo ngcono ukudluliselwa excitation kusukela emsipheni imisipha lwamathambo, izibilini zalo iso agqamise yonke imiphumela cholinergic, futhi ngoba sithuthukiswe motility emathunjini, kwandisa ithoni bronchial, isinye, endocrine nezindlala futhi uketshezi.

Ukulungiselela "Neostigmine" esikhishwe hhayi kuphela ngesimo isixazululo umjovo, kodwa futhi ngesimo amaphilisi, granules, zazo silungiselela ukumiswa setemlomo (izingane).

izinkomba

Wathi nomuthi isetshenziswa khona myasthenia, ukukhubazeka kanye paresis, iziyaluyalu motor umsebenzi ngemva okulimala ebuchosheni, neuritis, encephalitis emva, uvendle kanye tuberculous meningitis.

Iphinde isetshenziselwe lapho isidingo ekwelapheni optic nerve yoma, ukwehlisa ingcindezi intraocular e-glaucoma luyanda, futhi uma kunesidingo constriction we umfundi. Kulezi izifo, izidakamizwa isetshenziswa ngendlela iso amaconsi.

Kusho "Neostigmine" (imijovo) isetshenziselwa lokungeniswa zomsebenzi, futhi ine umphumela analgesic. Ngokuvamile izidakamizwa isetshenziswa ekwelapheni, it is baphathwa khona usebenzisa atony we esiswini, esinyeni kanye wamathumbu, uphuzwe ngomlomo.

Izidakamizwa "Neostigmine" imijovo, kanye nezinye izinhlobo zomuthi, isetshenziswa kuphela kadokotela, nokuvumela izinhlelo zayo ezimele yayihlanganisa akuvumelekile.

Uma izidakamizwa sisetshenziswa ngomlomo, umthamo yayo ngoba umuntu omdala kuyinto komunye wokuhamba nanhlanu kumakhulukhulu amagremu bayiswa izikhathi 3 ngosuku. Izingane ezingaphansi kweminyaka engu-eziyishumi - omunye senkulungwane a igremu unyaka ngamunye okwalandela, kepha hhayi ngaphezulu kuka 0.01 amagremu ngosuku.

Ukulungiselela "Neostigmine" (imijovo) ingasatshenziswa kokubili phansi kwesikhumba futhi intramuscularly ku-inani 1 ml isixazululo 0.05% iqondiswa izingane ngokusho ml leshumi ngonyaka, kodwa asisikhulu kunenkosi 0.75 ngemililitha, zonke owawenza elilodwa noma amabili izikhathi. Ubude obuphelele ukwelashwa incike ngobucayi isifo futhi kungaba kusuka 15 kuya 40 izinsuku, futhi kwezinye izimo ngisho isikhathi eside.

Uma kukhona zabasebenzi ababuthakathaka, lesi sidakamizwa "Neostigmine" (ampoules) kumele sisetshenziswe imijovo ongama , futhi ngesikhathi esifanayo wasungula esebenzisa "Atropine". Lokhu kwenziwa kanye kuphela ukungena kuqala noma umjovo. Futhi, izidakamizwa iqondiswa ngomlomo imali 0,003 g zonke izikhathi 40 amaminithi 6, kanye imijovo wenza 0.05% isixazululo izikhathi 2 ihora in 1.0 ml.

Ukuze umuntu omdala, umthamo sangemihla 0.05 g, futhi lo msebenzi kumele singeqi nanhlanu kumakhulukhulu amagremu. Ngokuphathelene imijovo, umthamo esiphezulu ngelanga kuyinto 0.006 g, umthamo owodwa we-angaphezu kwamabili thousandths of a igremu.

Imiphumela engemihle

Ngemuva kwesicelo of wathi ekwakhiweni zingavela bradycardia nohudo, ukucanuzela kwenhliziyo, kunciphisa umfutho wegazi, kukhuphuke uketshezi bronchial, ubuthakathaka kanye komzimba.

Uma umuntu sohudo ubuhlungu besisu, kanye ethela umjuluko, libonisa umphumela anobuthi kusho "Neostigmine". izidakamizwa "Atropine" phansi kwesikhumba injected ezimweni ezinjalo.

Awukwazi ukusebenzisa imithi ebukhoneni yisithuthwane ngokulandelana kwawo, kukhuphuke imisipha ithoni, isifuba somoya bronchial, angina, isifo sokuqina kwemithambo yegazi, futhi ukungabekezeleli lokhu izidakamizwa.

Izidakamizwa "Neostigmine": Izibuyekezo

Phendula kahle kule nokulungiselela abantu abaphethwe myasthenia gravis, njengoba kwenziwe ngosizo njalo yokwelapha yesondlo.

Isilinganiso iziguli luhlobo "Neostigmine" kuyadida uma abanye bazenza imijovo njalo, kanti abanye baye bazimisa uyisebenzisa kuphela ezimweni ezingandile, futhi abanye asikubekezeleli. Njengoba i- side effect, iziguli eziningi uqaphela ukubukeka njengomuntu nomlomo owomile futhi amathe ngokweqile futhi nokuquleka.