"Idrinol": yokusetshenziswa. Ukubuyekeza, amanani, izincazelo ukulungiswa

Yini izakhiwo izidakamizwa "Idrinol"? Yokusetshenziswa nezici kwemithi izimali izokwethulwa kulesi sihloko. Siphinde ngikuxoxele kwindlela wathi nomuthi ukukhululwa, ukuthi kubiza malini, lokho side effects okuyokwenzeka ngemva ukusetshenziswa, likhona yini contraindications, njll

Ukwakheka izimali, ezakheke, incazelo kanye emaphaketheni

Ngayiphi ifomu idedela izidakamizwa "Idrinol"? Yokusetshenziswa usitshela ukuthi lokhu izidakamizwa udayiswa isixazululo senzelwe parabulbarno futhi abaphathi emthanjeni.

nomuthi Okubukwe uketshezi kungekho nto enemibala emihle okusobala. ingxenye yayo iyasebenza izenzo meldonium dihydrate. Njengoba amanzi excipient esetshenziswa distilled.

Isixazululo izidakamizwa okuthengiswa izitsha eziyisikhombisa (1 ml) ezibekwe ku emaphaketheni plastic Valium (5 izingcezu), bese - ku amakhadibhodi amabhokisi.

pharmacodynamics izidakamizwa

Kuyini lokhu izidakamizwa ngokuthi "Idrinol"? Yokusetshenziswa uthi izidakamizwa zalo asebenzayo (meldonium) kuyinto analogue isakhi gamma-butyrobetaine, okusho ukuthi isici okuyinto ekhona kuwo wonke amangqamuzana zomzimba womuntu.

Meldonium ukwazi zivimbela gamma-butirobetaingidroksigenazu, ukunciphisa carnitine zamagama, okunamafutha acid ezokuthutha (chain eside) ngokusebenzisa ulwelwesi cell kanye zivimbela ekuqongeleleni therein amafomu unoxidized yasebenza ye-fatty acid, okuyi A nemikhiqizo atsilkoenzima atsilkarnitsina.

Umgomo we operation

Uyini umthelela umzimba womuntu imithi "Idrinol"? Yokusetshenziswa iqukethe ukwaziswa kulesi kwenqatshwa, ischemia, bebheka bonke izidakamizwa uyakwazi ukushayela yakhoibrium-mpilo ukulethwa izinqubo ukusetshenziswa yayo kumaseli, futhi ukuvimbela ukwephulwa of ATP ezokuthutha. Ngaphezu kwalokho, izidakamizwa oyenza glycolysis, okwenzeka ngaphandle ukusetshenziswa O _2. Ngemva wehlise lokuhlushwa carnitine iyaqala uye wakwenza kwemiqondo gamma-butyrobetaine, okuyinto kunomphumela vasodilating.

Umgomo we isinyathelo zomuthi inquma nemiphumela yaso kwemithi: ukunciphisa izimpawu overstrain ngokomzimba nangokwengqondo, ukwanda ngokuphawulekayo e kahle, ukusebenza kwawo amasosha omzimba humoral nezicubu.

Kufanele futhi wazi ukuthi lo izidakamizwa kunomphumela cardioprotective. Ngo ischemic ukulimala esivimba amanzi (acute) uyakwazi ukubambezela kumiswa necrosis esishintshashintshayo futhi ukunciphisa isikhathi nokuvuselelwa. Phakathi senhliziyo nomuthi ithuthukisa ukubekezelelana ukuze ukucindezeleka ngokomzimba, kuthuthukisa contractility esivimba amanzi, kunciphe ukuvama ukuhlaselwa. Ngo chronic acute cerebrovascular izidakamizwa ischemic angathuthukisa kwegazi legazi (kuhlanganise focus ischemic). Kufanele kuqapheleke futhi ukuthi lezi ithuluzi ephumelela kakhulu esimweni izilonda semithambo we fundus. Ngaphezu kwalokho, izidakamizwa ngokushesha aqede ukushayisana isimiso sezinzwa in iziguli ukuba umlutha wotshwala okungamahlalakhona (ikakhulukazi inkathi bashabalala).

I pharmacokinetics zomuthi

Kuthatha isikhathi esingakanani ukuba ukumuncwa imithi "Idrinol"? Yokusetshenziswa, osokhemisi yangempela wazise iziguli ukuthi lokuhlushwa eliphezulu kakhulu izidakamizwa egazini kufinyelelwa cishe ngokushesha ngemva kokuba abaphathi. Emzimbeni womuntu, it is akheka ukwakha metabolites ezimbili ezinkulu. Basuke isuselwe nezinso. Impilo kwesigamu umuthi amahora mayelana 4-6.

ubufakazi

Enemithi ukuyidedela, azikwazi ukuthengwa ekhawunteni ngaphandle idokhumenti olufanele, njengoba nje uthanda. Nomuthi "Idrinol" ibhekisela ngokuqondile zezempilo enjalo. Ayekusho? Ngokusho imiyalelo, umuthi kumele kusetshenziswe ngaphansi isifo uthi ezilandelayo:

• ingxenye ukwelashwa eyinkimbinkimbi cerebrovascular disorder imvelo acute (isifo cerebrovascular nonhlangothi ischemic);
• enciphile umthamo ukusebenza, kanye ukucindezeleka ngokomzimba (kufaka phakathi abantu abathintekayo kwezemidlalo);
• ingxenye eziyinkimbinkimbi ekwelapheni ischemic isifo senhliziyo (isilethikusebenza futhi pectoris angina) kanye dyshormonal kardimiopatii futhi ezingalapheki ukuhluleka kwenhliziyo;
• ukwelapha nokopha e hemophthalmia futhi retina imvelaphi ezahlukene, emaphakathi ngwengwzi vein thrombosis, namagatsha alo, retinopathy zasezindaweni ezihlukahlukene (sikashukela noma abanomfutho wegazi ophakeme);
• ukwelapha bashabalala syndrome, okuyinto eyenzeka ngo-ukuluthwa utshwala okungamahlalakhona (lihambisana yokwelapha ethile).

Izimo

Kungaphansi kwaziphi hhayi izimo ungasebenzisa izidakamizwa "Idrinol"? ochwepheshe lezivakashi bathi leli thuluzi is hhayi Kunconywa in iziguli hypersensitivity kuya isithako zomuthi, lenyuka ingcindezi intracranial (intracranial izimila kanye iziyaluyalu outflow emithambo yegazi), kanye ngaphansi kweminyaka eyi-18 (kusukela izidakamizwa ezingekho isethi iphephile futhi isebenza ngempumelelo ).

Kufanele kuphawulwe ukuthi iziguli ezine-kahle izinso umsebenzi futhi isibindi kumelwe sisebenzise nomuthi kubhekwe ngokucophelela okukhulu.

Umthamo nomuthi nezindlela zokuthola

Lapho ukusebenzisa izidakamizwa "Idrinol", intengo oboniswe ngezansi? Ngenxa umphumela kungenzeka zomuthi okujabulisayo kufanele ufake engxenyeni yokuqala yosuku.

Njengengxenye ukwelashwa okuhlanganisiwe senhliziyo pathologies nomuthi iqondiswa ngemithambo yegazi ngesikhathi 0.5-1 g (isb 5.10 ml) parabulbarly noma 100 mg / ml. Lezi ngemithamo ingasetshenziswa ngesikhathi esisodwa noma ulwahlukanise ku bentando ezimbili.

Inkambo yokwelashwa nale umuthi izinsuku 10-14. izifundo okuphindaphindayo ukhethe udokotela (ngokuvamile izikhathi 3 ngonyaka).

Endabeni ka kokunikezwa kwe-kwegazi ebuchosheni (isigaba acute) nomuthi parabulbarly iqondiswa 100 mg / ml noma 500 mg ngemithambo yegazi (ngamanye amazwi, 5 ml). Umjovo Kwenziwa kanye ngosuku izinsuku eziyi-10.

Ngezinye kahle esincishisiwe, kodwa futhi ngokomzimba ukuzikhandla ngokweqile izidakamizwa iqondiswa ngemithambo yegazi nge 500 mg (ngamanye amazwi, 5 ml) parabulbarly noma 100 mg / ml kanye ngosuku. Inkambo yokwelashwa - 2 amaviki.

Lapho ukuhoxiswa syndrome ukuthi kuzibonakalisa ukuluthwa utshwala okungamahlalakhona, izidakamizwa iqondiswa ngemithambo yegazi ngesikhathi 500 mg (ngamanye amazwi, 5 ml) parabulbarly noma 100 mg / ml kabili ngosuku. Isikhathi kwelashwa kwezinsuku 10-14.

Lapho kulungiselelwa isetshenziswa ophthalmopathology parabulbarno 50 mg noma 0.5 ml izinsuku ngemithambo yegazi-10, ezihlanganisa ukuvivinya inhlanganisela.

side effects

Njengoba izidakamizwa ibekezelelwe "Idrinol"? Imijovo Cishe zamenza engemihle. Nokho, ezimweni ezingavamile, ezinye iziguli namanje akhononde Ukuwohloka impilo. Ukusabela ezivamile:

• Kwemizwa uhlelo (central): ukuyaluza.
• Izikebhe inhliziyo: engezansi noma, kunalokho, kukhuphuke blood pressure, tachycardia.
• ipheshana wokugaya ukudla: iziyaluyalu dyspeptic uhlamvu.
• Yokungezwani komzimba: ukuqubuka, isikhumba ukulunywa, ngamanzi kwesikhumba, edema angioneurotic, eosinophilia.
• Okunye: ubuthakathaka jikelele.

Izidakamizwa "Idrinol": nozakwabo kanye nezindleko

izidakamizwa Okubukwe inezinto eziningi analogue. Phakathi ephumelela kunazo kukhona izindlela ezilandelayo: "Angiokardil", "Mildronat", "Vazomag", "Mildroksin", "Kardionat", "Midolat", "Medatern", "Melfor", "meldonium".

Kungakanani ngumuthi "Idrinol"? Intengo lo mkhiqizo awukho eliphezulu kakhulu. Ngokwesilinganiso, 5 izitsha eziyisikhombisa imithi kuzodingeka akhokhe ruble Russian mayelana 150.

Izibuyekezo

Yini iziguli uthi ngemithi enjalo, njengoba "Idrinol"? Izibuyekezo bathi lokhu izidakamizwa kahle lapho zibhekene nomsebenzi. Odokotela bagcizelele: uma ulisebenzisa ngokuvumelana izinkomba, kuba ngempumelelo ephatha acute cerebral iziyaluyalu kwegazi, ischemic isifo senhliziyo, kanye nokuqaleka okwenzeka ukuluthwa utshwala ezingamahlalakhona. Ngaphezu kwalokho, lokhu izidakamizwa kahle kwandisa ukusebenza kahle futhi aqede uhlobo ngokomzimba.

Kufanele wazi futhi ukuthi iningi iziguli ejabulisa amanani aphansi zomuthi.

Izinsuku, isitoreji nokusakazwa izimo

Kadokotela, okuyilokho, eqinisweni, izidakamizwa kweqiniso "Idrinol" ingasetshenziswa hhayi okuthandayo. Kufanele ukhethe udokotela.

izidakamizwa Okubukwe kungokwalabo B. uhlu Umuthi kumele agcinwe ezingeni lokushisa hhayi ephakeme kunaleyo 26 ° C ngo-kude nezingane. I nomuthi akumele simisiwe. Impilo eshalofini zomuthi sekuyiminyaka emithathu.