"Asparkam": analogue, yokusetshenziswa

Ukuthaka imithi elawula izinqubo umzimba umzimba, kukhona elinye iqembu kwezidakamizwa ngokuvamile asetshenziselwa ukwelapha izifo zonke. Ungakuvumeli lokhu ibinzana akubonakali engacacile lutho, kuyiqiniso. Noma yimuphi isifo, noma iyiphi inqubo sokugembula okwenzeka emzimbeni wethu, ephelezelwa kuphula umthetho we izinqubo umzimba emangqamuzaneni. Futhi ukuthi ukulungiswa iziyaluyalu umzimba e iningi kuholela ekululameni. Omunye izidakamizwa ezisetshenziswa ukulungiswa kuphazamiseka kusho umzimba "Asparkam". It is ebekiwe pathologies eziningi. Ake sibheke "Asparkam" analogue zomuthi ezisetshenziswa namuhla.

kwebalingisi kwemithi ye "Asparkama"

Njengoba sekushiwo, ukulungiswa "Asparkam" libhekisela eqenjini kwemithi ezithinta izinqubo umzimba emzimbeni. Lo mshini wezenzo zomuthi kusekelwe la maphuzu alandelayo.

Eqinisweni ngempela ukuze njalo le intracellular Ukwakheka ionic medium baziwa. Ngokukhethekile ikhokhelwa ukuze izinqubo weseli umzimba potassium ne-magnesium ion. Ngenxa ikhono okuthiwa asparginatov (ingxenye izidakamizwa) ukubamba iqhaza intracellular ion ezokuthutha lokuphatha "Asparkama" kunomthelela ekwandeni ingqondo kanye ngcono cell umzimba.

Ngoba umzimba omkhulu mncane zilalela Ukungadli ion (ikakhulukazi potassium ion), inhliziyo, "Asparkam" liveza umphumela cardioprotective ususe Ukungadli ion e cardiomyocytes. Lokhu sibonakalise ukwehla excitability futhi conduction izinqubo, lokubonakala umphumela antiarrhythmic zomuthi.

Through the ithonya okuqukethwe "Asparkam" magnesium ion kuthinta solwazi-sodium potassium futha, ukunciphisa okuhlushwa sodium vnutriklutochnuyu futhi icubungula iqhaza repolarization we ulwelwesi cell. Ukwanda e ulwelwesi ezingaba kuholela yokuthi ukuthi ayimbijana calcium ion in the cytoplasm ubambe iqhaza ezinhlelweni zokwenziwa we electromechanical elihlangana actin futhi myosin cardiomyocytes.

Asparginat kwalokho, ingxenye izidakamizwa, ikhuthaza ukusebenza kwawo izinqubo umzimba, kwandisa hhayi kuphela zamagama acid acid, kodwa futhi synthesis amino ushukela kanye lipids, ehilelekile ukulawulwa umzimba intracellular. Leli qiniso sithuthukisa umzimba amandla kule ischemic kwezicubu esivimba amanzi futhi amasayithi. "Panangin" - Analogue "Asparkama" - ngenxa yokuqukethwe ezifanayo potassium ne-magnesium asparginata liveza imiphumela efanayo pharmacodynamic. Leli qiniso kunomthelela esifana nokudlanga "Pananginum" umkhuba noma zenhliziyo.

Izimfanelo pharmacokinetic ka

Sam "Asparkam" analogue we umuthi ngokushesha futhi cishe ngokuphelele faka kwegazi. Excretion zomuthi senzeka ikakhulu esebenzisa nezinso. Ngemva umthamo owodwa izidakamizwa esiphezulu lokuhlushwa ekusakazeni igazi kufinyelelwe ngaphakathi 1-2 amahora. "Asparkam" egazini uwela njengoba ion of potassium, magnesium kanye asparginatov amaseli bese uqala iqhaza izinqubo zabo umzimba.

izinkomba

ifomu Tablet "Asparkam" ekwakhiweni okuhloswe (futhi yasetshenziswa ngempumelelo) ekwelapheni izifo ezihambisana ne esingamahlalakhona senhliziyo ebuthaka. Ngakho, ekhombisa endaweni kungaba isimo postinfarction isimo ngemuva cardioversions noma ephelezelwa arrhythmia futhi conduction esivimba amanzi. "Asparkam" kuyinto ekwelapheni yinhliziyo nokusetshenziswa ka glycosides inhliziyo, kanye ezimweni ukweqisa izidakamizwa noma okunoshevu saluretikami (izidakamizwa isisu ukuthi ngaphandle okwandisa diuresis ekuthuthukiseni ukukhuthaza ukususwa ion emzimbeni).

Ifomu komjovo "Asparkama" iye yasetshenziswa ngempumelelo kule yokwelapha eyinkimbinkimbi ezingamahlalakhona ukumelwa inhliziyo, kuhlanganise infarction post-esivimba amanzi, iziyaluyalu isigqi conduction therapy elihlangene.

Izimo izidakamizwa

Ngenxa yokuthi "Asparkam" iqukethe esiningi magnesium potassium ion, it is contraindicated ngesikhathi ukwehluleka oyingozi futhi ezingalapheki kwezinso, kanye lenyuka luvelo eyodwa noma ngaphezulu yezingxenye izidakamizwa.

Ngo ukushaqeka cardiogenic (lapho systolic blood pressure lehla ngezansi 90 mm HG. V.) Ingabe hhayi Kunconywa ukusebenzisa "Asparkam" analogs. Yokusetshenziswa ibonisa ukuthi izidakamizwa nakho contraindicated e isifo Addison futhi obusebenzayo esingamahlalakhona adrenal, ezimeni lesiguli vysokostepennoy atrioventricular isivimbo wokuqukethwe lelisetulu potassium ne-magnesium ion e oketshezini olungenambala lwegazi.

Umthamo nokuPhatha

Uma usebenzisa uhlobo ithebhulethi "Asparkam" izidakamizwa ukuthatha amaphilisi elilodwa noma amabili ngemva kokudla kathathu ngosuku. Isikhathi ukuphathwa kunqunywa udokotela ukuba khona esekelwe Yiqiniso basemtholampilo isifo nedatha laboratory kanye nezindlela wezinsimbi.

Ifomu komjovo inikezwa kuphela ekuphathweni emthanjeni. Okuqukethwe omunye isitsha kumele ziyoncibilika 50 noma 100 ml oyinyumba isotonic isixazululo glucose, iqondiswa ngemithambo yegazi kancane. ekuphathweni okuphindaphindayo kungaba liphindwe kungekho ngokushesha kunezinsuku amahora 4-6 emva odlule lapho uya khona "Asparkam" ukulungiselela. Analogs zomuthi (isb, "Panangin") abelwa ezifanayo. "Panangin" like "Asparkam", unomthelela evelele ku umzimba myocardiocytes. Ngakho-ke, lokhu Analogue "Asparkama" ngesiRashiya kabanzi lisetshenziswe izibhedlela nezenhliziyo.

side effects

Uma kwenzeka ukuthola ifomu tablet may okuvela iziyaluyalu pheshana emathunjini, okuyinto ziyabonakala ubuhlungu epigastric evutha, isicanucanu, ukuhlanza. ekuphathweni esingapheli singenza izilonda we mucosa.

Kusukela izidakamizwa unomthelela oqavile ku esimiso senhliziyo nemithambo yegazi, kungxenye yayo kungadala arrhythmias, conduction thuthuva, vimba atrioventricular, ukwehlisa wegazi.

isimiso sezinzwa amanothi okuvela paresthesia, ukuluma, ukudikiza.

Ngenxa okuqukethwe eliphezulu magnesium ion futhi Ukungena zabo zibe isimiso sezinzwa esiyinhloko kungase zokuphefumula ukucindezeleka umsebenzi. kaningi futhi kumakwe ukwethulwa lokujabulela ukushisa "Asparkam" izidakamizwa. Analogs zomuthi unezimpawu ezifanayo ukusabela ezingezinhle futhi ukuvama nesenzakalo yabo. Ngenxa yalokhu, qiniseka ukucela ukwamukelwa lesiguli ngaphambi zomuthi.

imiyalelo Special ukusetshenziswa "Asparkam" izidakamizwa

Analogs izingane kabanzi iziguli ezingane, nakuba okwamanje idatha esanele ukusetshenziswa "Asparkama" ezinganeni. Naphezu kwalokhu, izidakamizwa iye yasetshenziswa ngempumelelo ekwelapheni izifo zenhliziyo e Pediatrics.

Uma impatho eside "Asparkama" Kunconywa zokuqapha ngokucophelela electrolyte e-plasma, ukuqapha imingcele electrocardiographic. Futhi ngokucophelela okukhulu izidakamizwa isetshenziswa in iziguli isigqugquzeli potassium amazinga e oketshezini olungenambala lwegazi.

"Asparkam": nozakwabo

Phakathi wemithi emakethe wamanje ejwayelekile "Asparkam" umuthi ukunikeza "Panangin". Ngekhono okusezingeni eliphezulu, i-analog asebenzayo "Asparkama" sisetshenziswa kabanzi eRussia njengoba ine isakhiwo ezifanayo futhi ngokulandelana izinkomba ezifanayo. Nezenhliziyo umkhuba isibonelo. Ngakho, "Panangin" - fanekiso ukuba "Asparkama" nge ukwakheka efanayo.

Phakathi kwezinye izidakamizwa kokuba nomphumela ofanayo Kumele kuqashelwe, "Inosine" "Riboxinum" "Meksaritm" "Propanorm" "Ritmokard".