I-agent ye-hypotensive "i-Physiotenses". Imiyalo yokusetshenziswa

Igama lomhlaba jikelele lomuthi "I-Physiotenses" lizwakala elifana negama lezinto ezisebenzayo - moxonidine. Isidakamizwa esithi "Physiotenses" sibhekisela eqenjini lezidakamizwa ezihloswe ukwelashwa kwezifo zesimiso senhliziyo. Kuyinto engxenyeni yegciwane lemithi enezimpawu ezibizwa ngokuthi i-hypotensive futhi iqhubeka nomugqa wezidakamizwa-izidakamizwa.

Ngaphandle kwe-moxonidine esebenzayo, amaphilisi e-Physiotens aqukethe iqembu labantu abathandekayo njenge-lactose monohydrate, i-crospovidone, i-gynromellose, i-stearate ye-magnesium, i- ethylcellulose, i-talc, i-macrogol, nabanye ngokuncane. Indlela kuphela yokukhululwa kwezidakamizwa "Imiyalo ye-Physiotenses" yezingcingo zokusebenzisa amakhobulethi aphethwe ngamasethini ahlukene. Ukuthatha imithi kusiza ukunciphisa ukucindezelwa kwegazi kanye nokuphikisana kwemisipha.

Kukhona izici ezinhle ze-pharmacokinetic zokulungiselela ukulungiselela "Physiotens", okucishe ifakwe ngokuphelele ezingxenyeni ezingenhla zomzila wokugaya futhi ufinyelele ukuhlushwa okuwusizo okungakapheli phakathi kwehora. Umuthi ungathathwa ngaphambi noma emva kokudla, lokhu akuthinti ukufana kwawo. I-moxonidine engaphezu kuka-90% esebenzayo idutshulwe izinso zingakapheli amahora angu-24, isakhi sishiya kuphela u-1% wezinto ezivela emathunjini.

Iziguli ezinokungafinyeleleki ngokweqile zeluleka ukuba zikhethwe ngokuzikhethela umuthi we-"Physiotenses", imfundo yokusetshenziswa ibonisa isikhathi esifushane sokususwa okuphelele kwesidakamizwa esivela emzimbeni kwiziguli ezinezifo ezifanayo. Kuphawulwe futhi ukuthi ezinye zezinto ezisebenzayo ziyadluliswa ngesikhathi senqubo ye-hemodialysis.

Isidakamizwa esithi "i-Physiotenses" ibhekisela kwizidakamizwa ngezinyathelo ezimbalwa zesenzo, isibonakaliso kuphela sokusetshenziswa kwezidakamizwa ngumfutho wegazi ophezulu.

Umuthi "Physiotenses". Ukuqhathaniswa nemiphumela emibi

Njenganoma yikuphi, uma ukubeka umuthi, okokuqala, ukunakekelwa kubhalwa ukuthi kungenzeka ukuxhaswa kwamagciwane kumakhemikhali, okuba yi-contraindication ecacile ekusetshenzisweni kwayo. Endabeni yokuqokwa kwemithi ye "Physiotens", kunezinye izincomo eziningana zokukhansela kwayo njengendlela yokulungisa:

- i-bradycardia eyaziwa;

- I-syndrome yobuthakathaka be-node yesusus.

Ukunakekelwa kufanele kuthathwe ukuphatha iziguli ezingaphansi kweminyaka engu-18, ngoba kuze kube manje, umkhuba wezokwelapha awusunganga izinga lokuphepha nokuphumelela ekuthatheni imithi "Physiotens". Izincomo ezifanayo kufanele zicatshangelwe ezigulini ezinokuhluleka okukhulu kwezintambo zesimo esingapheli ngesikhathi se-hemodialysis. Ngenxa yokuntula kolwazi ngokuphumelela kokwelashwa ngokuqapha, misela izidakamizwa ezigulini ezingasebenzi kahle.

Ukwelashwa okujulile kanye nesilinganiso se "Physiotens" kufanele kuthathwe ngokungathí sina, imiyalo yokusetshenziswa isexwayise ngokuthi kungenzeka imiphumela emibi evela kwezinye izinhlelo zomzimba.

I-CNS: ukuguga noma ukuphazamiseka kokulala, isizungu nesihloko.

Ipheshana lesisu: kuhambisane nesicathulo nesomlomo omile.

I-CCC: ukuthuthukiswa kwe- hypotension ye- orthostatic, ukwehla okuqinile kwegazi.

Ngokuvamile ukuphendula kwe-allergen kugcinwa ngendlela ye-pruritus ne-rash, kwezinye iziguli angioedema zenzeka .

Ukunciphisa ubunzima bezimpawu zezenzakalo ezimbi kubonakala phakathi kwamasonto okuqala wokuthatha lesi sidakamizwa.

Izimpawu zokudlula ngokweqile kwe "Physiotens". Imiyalo yokusetshenziswa endleleni yokuxazulula ngayo

Izimpawu ezivamile ezinokudlula ngokweqile kwalesi sidakamizwa zihlanganisa:

- ukulala, ukuguquka ;

- ikhanda nokunciphisa ngokweqile kwegazi;

- ukuhlanza, ukukhathala, ubuhlungu besisu.

Ezimweni ezingavamile, kune-hyperglycemia kanye ne-tachycardia.

Ukususwa kwemiphumela emibi yokudlula ngokweqile kunemvelo, ayikho antidotes ekhethekile emithi okwamanje.

Ukunciphisa ukwelashwa kwezidakamizwa kunconywa, ukunciphisa kancane kancane umthamo.

Ayikho imiyalelo ekhethekile mayelana nemibandela nemigomo yokugcinwa kwemithi ye-"Physiotens", kwanele ukugcina umbuso wokushisa ovamile (hhayi ngaphezu kwama-degree angu-25), isikhathi esichazwe kuphakheji, nokuthola indawo emnyama, engatholakali yabantwana.