Gilbert Syndrome. ekuxilonga, imiphumela

Gilbert Syndrome, kuba lesisifo? Gilbert Syndrome - abanomoya kakhulu okufana emitholampilo hyperbilirubinemia sokusebenza. Lesi sifo ubonisa UGT1A1 isakhi sofuzo wezakhi. Ngenxa kuye, enzyme ufakwe ngumuntu UDP. Gilbert Syndrome libhekene okulandelayo:

1. Amazinga aphakeme igazi bilurbina
2. Kwengxenye ukwehluleka glyukuroniltransferazy
3. Ukungabi bikho ushintsho hepatic
4. Ukuncishiswa bilirubin ephakeme ngenxa isenzo phenobarbital

Ngokokuqala ngqá Gilbert Syndrome watholakala ngo-1901, odokotela French Gilbert Nicolas Augustin futhi Lereboullet P. Baveza ukuthi ungubani syndrome ngokuthi "cholehemia umndeni". Ngemva kwalokho, kwasikiselwa amagama ambalwa, kodwa wayeka ku Gilbert Syndrome. Lesi sifo ngokuvamile kwenzeka e amadoda abaneminyaka engu 25-30.

Izimpawu ejwayelekile izifo

Kubantu, kukhona ukukhathala, kwesokudla quadrant colic zenzeka. Ukubonakaliswa eyinhloko lesi sifo ukukhathazeka umbala ngesineke. Ngezinye izikhathi kuyenzeka ukuthi yellowness akusilo obonakalayo, kanye umuntu efunda ngesifo kuphela ngemva kokuba ibambe umzimba kwamakhemikhali. Kunezinhlobo ezimbili zama-lesi sifo: episodic futhi ezingalapheki. Uma umuntu ngokwenyama ngokweqile emzimbeni wakho, i-jaundice kungenzeka. Ngaphezu kwalokho, ukusebenzisa kabi utshwala, yokulamba kungaba "ukuqala" sokuthuthukiswa sifo.

Gilbert Syndrome uphethwe.

bilubirin sekukonke ngesikhathi isifo kungenzeka ezingeni 21-51 mmol / l, lapho kungenzeka ukwandisa ezingeni 85-130 micromoles / ilitha. Ukukhomba lesi sifo, kudingeka kudlule ukuxilongwa ekhethekile. Kungaba ngezinhlobo eziningi.

1. Hlola indlala. Ikakhulu esetshenziswa ephansi fat Ukudla, okungenani - ukudla amahora angu-48. Ngakho lokuhlushwa bilirubin ku inyuka igazi.
2. Hlola pentobarbital. Ukusetshenziswa kwalesi imithi kuholela ukukhuthazwa glyukuroniltrasferazu enzyme umsebenzi, ngaleyo ndlela kuncishiswe lizinga bilirubin.

ekwelapheni lesi sifo

Noma yimuphi ukwelashwa okukhethekile, ngokuvamile, akukho, ngoba isici i umzimba, akusona isifo. Vele ogulayo contraindicated mthwalo owengeziwe, kumelwe ulandele uhlobo olukhethekile lokudla. utshwala ngoba umuntu onjalo engafa kungavunyelwa ngoba ukusetshenziswa kungaholela ukuthuthukiswa lesi sifo. Kodwa kuwufanele ukukhumbula ukuthi amacala Gilbert Syndrome akudingekile ukuba senqabe imigomo. Phakathi okhulisa jaundice odokotela linqume ukudla ukudla okuthile, ukwelashwa vithamini ukhiqizwa yisikhumba uma ebekiwe.

syndrome imiphumela Gilbert sika

Labo abayithola Gilbert Syndrome, imiphumela kwezinhloso zenzuzo, kanye indlela isifo sizothinta isibindi. Eminye yale miphumela akukwazi nhlobo, kodwa kungcono ukwenza i-ultrasound kwesibindi, kanye ukuhlolwa igazi for bilirubin. Ukuze kwesibindi abephule phezu ukuthola Gilbert Syndrome, udinga unamathele ukudla, futhi qinisekisa ukuthi ukuzivocavoca. Ngezinye izikhathi imiphumela lesi sifo engaveza njengoba lezivakashi sombala steatosis. Ngokuyinhloko, le miphumela kuyagcinwa ezingabantu. Ngakho-ke, amadoda uhlushwa sifo kudingeka ukuqapha impilo yabo.

Yiziphi izibikezelo ukubeka ogulayo?

Lesi sifo angabhekwa okuhlukile kuyinsakavukela. Laba bantu abhekwa engconywana, kulapho ngakho ekwelapheni ekhethekile akudingeki. Naphezu kweqiniso lokuthi hyperbilirubinemia zigcinwe ukuphila, Gilbert Syndrome aliholeli ukufa. Kukhona kungenzeka kuphazamiseka zengqondo, futhi cholelithiasis. Imiphumela yalesi sifo zingase zingabonakali kuze kuphele iminyaka engu-20, kodwa ngaso sonke isikhathi sihambisana umuntu, kulapho ukuthi angasebenza ufuzo isici. Into ebaluleke kakhulu ukuthi lesi sifo akuyona ikakhulukazi nomthelela kumsebenzi womuntu.