"Domidon": yokusetshenziswa, futhi ziyini

Nge iziyaluyalu nemisebenzi yokusetshenziswa pheshana wokugaya ukudla wabhekana wonke umuntu. Ngokuvamile, ukungakhululeki esifundeni epigastric zivele ngenxa ukungondleki nokungafanele. Ukuze kugayeke futhi ukusheshisa bethulula esiswini gastroenterologists Sisikisela ukuthatha izindlela ezikhethekile. Omunye wabo okubhekiselwe imithi "Domidon". Yokusetshenziswa, impendulo nokubonakaliswa lokhu izidakamizwa ethulwa ngezansi.

Ifomu, ukubunjwa, izidakamizwa emaphaketheni

Nomuthi "Domidon" imfundo lilondolozwe emaphaketheni eyenziwe amakhadibhodi, akhiqizwa ifomu tablet. Bona zimumethe domperidone, kanye izithako ezifana monohydrate lactose, povidone, corn isitashi, microcrystalline cellulose, ama-titanium dioxide, isitashi pregelatinized, magnesium stearate, sodium lauryl sulfate, polyethylene glycol 4000, methylcellulose hydroxypropyl noma sepifilm 752 Blanc.

Ngo ukudayiswa kulesi sikhungo eya amaseli nentaba.

kwemithi

Kuyini lokhu imithi ngokuthi "Domidon" (amaphilisi)? Iziyalezo yokusetshenziswa uthi kuba motility ivuselela GI. isimiso sayo wokusebenza alichaza ikhono ukuvimba ama-receptor D2-Dopamine. Ngenxa yalokhu umphumela kwandisa isikhathi ukunyakaza peristaltic e 12 tiperstnoj emathunjini futhi endaweni esiswini antral. Futhi ngesivinini bethulula kwezitho wathi futhi kwandisa ithoni emphinjeni (the sphincter engezansi).

Lo muthi akunamthelela uketshezi esiswini. Effect Its anti-emetic ngenxa inhlanganisela umphumela gastrokinetic, futhi bengathandwa ka Dopamine zemizwa chemoreceptor inhlamvu endaweni, lapho zitholakala ngaphandle kusivimbeli gazi ebuchosheni. Ngaphezu kwalokho, lokhu izidakamizwa eqeda hiccups nesicanucanu.

izici kinetic

Kuyini sici kinetics zomuthi "Domidon"? Yokusetshenziswa ibika ukuthi leli thuluzi ngokushesha futhi sokugxila ngokuphelele kusukela amathumbu. It is akheka esibindini futhi emathunjini ipheshana izindonga, lapho has a bioavailability ongaphakeme (azungeze 15%).

Encishisiwe esiswini asidi juice nokudla kakhulu ukubambezela futhi sinciphise ukumuncwa domperidone. isiqongo plasma wayo lokuhlushwa izuzwe ihora elilodwa emva ukungenisa.

Ukuxhumana zomuthi ukuze plasma amaprotheni cishe 91-94%. Kuyinto kahle lingena ngokusebenzisa Bbb, kodwa lenza kahle ubisi lukamama (ezingeni imayelana 1/4 of the lokuhlushwa Imininingwane egazini).

Ukuguqulwa begazi ukulungiswa Kwenziwa N-dealkylation futhi hydroxylation.

Isikhathi isigamu-ukuphila umuthi amahora 7-10. Ngo ukwehluleka kwezinso (esibi kakhulu), lesi sibalo liyakhuphuka.

Etholakale izidakamizwa kusukela umzimba kanye indle kanye nomchamo.

Izinkomba yokwamukelwa

Kwezinye izimo, abadala uqoke "Domidon" ithebhulethi? Ukusetshenziswa kwalesi izidakamizwa kuboniswe ukuhlanza nesicanucanu kanye ubuhlungu esiswini engenhla, umuzwa ukugcwala futhi isilungulela.

Njengoba izingane, abazincomayo ukuthi lesi sakhiwo kuphela isicanucanu nokuhlanza.

Izimo

Lapho hhayi ukusebenzisa izidakamizwa "Domidon" (yokusetshenziswa futhi uyini - konke kuyokhulunywa kulesi sihloko)? Izimo kwaleli thuluzi yilezi:

• ukopha emathunjini;
• hypersensitivity;
• perforation emathunjini / esiswini ;
• isimiso mechanical emathunjini;
• hypophysis isimila (prolactin-secreting);
• lihambisana amafomu ngomlomo "Erythromycin", "ketoconazole" noma ezinye inhibitor ka CYP 3A4, kanye ejenti okuyinto kwelule isikhawu Q-T.

Izidakamizwa "Domidon": yokusetshenziswa

amaphilisi Kubhekwe kumele ayiswe ngaphambi kokudla. Lapho ethola imithi ngemva kokudla ukudla okwenziwe ukumuncwa kwabo Kuthi kancane.

Izingane ezivela engu-12 kanye nabantu abadala, lokhu imithi ezinqunyiwe 10-20 mg kathathu ngosuku. esiphezulu I umthamo wansuku zonke izidakamizwa eneminyaka engu-80 mg.

Isikhathi yokwelapha eyinhloko - amasonto 4. Uma kudingekile, ukusetshenziswa ngokwengeziwe izidakamizwa liyadingeka bonana nodokotela wakho kuqala.

With ukuthuthukiswa ukwehluleka kwezinso kufanele kuncishiswe kaningi izidakamizwa. Ngokuphathelene yokwehluleka kwesibindi, kulesi simo, it akukashicilelwa.

side effects

Ingabe ukubukeka enqabayo ukusabela imithi "Domidon"? Yokusetshenziswa libike ukuthi imiphumela enjalo enqabayo ingabe zenzeka:

• kwamazinga prolactin;
• anaphylaxis ;
• uvalo, ukuyaluza;
• edema, kululwa isikhawu Q-T, palpitations, dysrhythmia nokushaya kwenhliziyo;
• nomlomo owomile, disorder extrapyramidal, ikhanda elibuhlungu, ukoma, ukuqwasha, ukucasuka, isiyezi, ukozela, ukucobeka, Ukudlikizela;
• izinkinga zesisu;
• gynecomastia, galactorrhea, amenorrhea;
• ukulunywa, dysuria;
• ukuchama kaningi, ukuqubuka kwesikhumba;
• stomatitis, conjunctivitis;
• asthenia, ubuhlungu emilenzeni;
• anda AST, ALT cholesterol.

izincomo ezithile

Yini okufanele azise nesineke, ngaphambi kokunika izidakamizwa "Domidon"? Iziyalezo yokusetshenziswa uthi leli thuluzi ayikwazi kuhlangene antisecretory nemithi antacid.

Ukuze ekwelapheni izingane ezingaphansi kweminyaka engu-12 ubudala nge esisindo esingaphansi 35 kg ukusebenzisa lolu imithi akufanele kube.

Phakathi ukwelashwa ngalo muthi kufanele uyeke ukuphathwa umgwaqo nokusebenza kwemishini yingozi.

Izibuyekezo umthengi

Manje ngoba sewuyazi ukuthi yini izici sici izidakamizwa "Domidon". Yokusetshenziswa futhi ukuthi kuyini, we thasisela ngenhla.

amakhasimende amaningi usebenzisa lesi sakhiwo libike ukuthi ngempumelelo aqede isilungulela, hiccups nesicanucanu. Futhi, izidakamizwa kunomthelela bethulula okusheshayo esiswini, ekunciphiseni umuzwa wobukhulu nokuphatheka kabi zisesilinganisweni esiphansi ngangokunokwenzeka.

Ububi kuphela kwalesi izidakamizwa inombolo enkulu yemiphumela emibi.