"Dipyridamole": yokusetshenziswa. "Dipyridamole": ukubuyekezwa kanye analogue

Uyini izidakamizwa "Dipyridamole"? Imiyalelo, intengo, izici, futhi izinkomba izimali izokwethulwa ngezansi. Siphinde bakutshele ukuthi kungenzeka ukuthola wathi izidakamizwa ngesikhathi sokukhulelwa, uma kuye kwadingeka iyiphi analogue, side effects kanye contraindications.

Ukwakheka, emasakeni nomumo

Ebonisa ukuthi ukulungiswa bhukwana imfundo? "Dipyridamole" - umuthi has uhlobo oluthile ukukhululwa. Ake sixoxe ngazo ngokuningiliziwe:

• Dragee 0.075 futhi 0.025, ketshezi asebenzayo le fomu dipyridamole. Umuthi okuthengiswa amaphakheji plastic yizicucu 100.
• "Dipyridamole" - izibhebhe 0,075, 0,005 futhi 0,025 g Camera, aqukethe ketshezi asebenzayo ezifana dipyridamole. Ngokuphathelene izakhi asizayo, lona wamuva zihlanganisa calcium stearate, monohydrate lactose kanye isitashi. Imithi okuthengiswa ibhamuza 120 noma 40 izingcezu, okuyinto ezibekwe inqwaba amakhadibhodi.
• Isixazululo for umjovo. Leli fomu lihlanganisa into esebenzayo efanayo. 0.5% isixazululo okuthengiswa izitsha eziyisikhombisa 2 ml.

pharmacodynamics

Yiziphi izindawo kubhekwa imithi? Yini-ke unamathisele yokusetshenziswa? "Dipyridamole" - umuthi kunomphumela vasodilating. Lezo-ke has ikakhulu izitsha yenhliziyo.

Umthamo ezamukelwayo nomuthi kuvimbela adhesion we-platelet kwandisa igazi ukugeleza rate, kuthuthukisa bese isihumusha isinyathelo angioprotective. Ngaphezu kwalokho, izindlela kuncike ikhuthaza kwegazi eseduze izitsha inhliziyo.

Asinakusho ukuthi izidakamizwa normalizes outflow emithambo yegazi. Ngakho-ke, ukudla layo njalo iyehlisa ingozi thrombosis, ikakhulukazi esikhathini postoperative.

Umgomo we operation

Yiziphi ezinye izidakamizwa anezakhi "Dipyridamole"? Manual ithi kusho kahle kwehlisa ithoni imithambo palsy. Kule ndaba, it is impela ngenkuthalo esetshenziselwa ukuhlasela ischemic lezivakashi. Ngaphezu kwalokho, kubhekwa izidakamizwa kuthuthukisa kwegazi ngokuphawulekayo esinomhlapho. Lesi sici kukuvumela ukuthi uvimbele hypoxia fetus.

Uyini lo mshini wezenzo zomuthi? Yiluphi ulwazi siqukethe imiyalo ephathelene nokusetshenziswa? "Dipyridamole" kwandisa umsebenzi adenosine futhi kunciphisa engachazeki kwezicubu. Wathi izidakamizwa kuthinta imisipha semithambo ngu ivimbela norepinephrine ukukhululwa, okuyilokho, eqinisweni, kubangele ukusikwa zabo, akhuphule umfutho wegazi futhi letindzala ukumelana semithambo.

Futhi kufanele kuphawulwe ukuthi ngenxa ekuvimbeni phosphodiesterase incipha ukukhululwa kwe activators aggregation platelet. Lesi sici kubavikela ababambelela. Ukwehla adhesiveness platelet kuvimbela amahlule izitsha.

Izidakamizwa "Dipyridamole", intengo oboniswe ngezansi, njengoba ngokuvamile amanxusa antiplatelet isetshenziswa lihambisana acetylsalicylic acid.

Pharmacokinetics

Ugxile kubhekwa indlela kunalokho ngokushesha. okuhlushwa wobuningi kufinyelelwe mayelana imizuzu 60 ngemva kokuphathwa.

Ukubuthelela ketshezi asebenzayo wenziwa myocardiocytes. Izidakamizwa asitholayo umzimba esibindini. Endabeni ka yephule lesi umzimba umsebenzi kungenzeka ekuqongeleleni.

izinkomba

Nomuthi "Dipyridamole" ebekiwe lezi zifo ezilandelayo:

• esingamahlalakhona senhliziyo imvelo ezingamahlalakhona;
• yokuvimbela occlusion of shunts futhi stents;
• angina;
• isilethikusebenza (hhayi kuphela esigabeni acute);
• pooling eyeqile lwemithambo thrombosis;
• unhlangothi ischemic;
• nokuvinjelwa thromboembolism, ikakhulukazi ngemva ukungenelela kuhlinzwa inhliziyo;
• esingamahlalakhona esinomhlapho;
• encephalopathy kwegazi;
• isifo sokuqina kwemithambo yegazi imilenze;
• iziyaluyalu microcirculatory yanoma yimuphi umsuka;
• glomerulonephritis;
• DIC e sepsis e ingane futhi toxicosis.

Izimo

Ngokusho imiyalelo izimali ayikwazi ukusetshenziswa uma lokuchezuka ezilandelayo:

• hypotension ;
• angina engazinzile;
• acute isilethikusebenza;
• hypersensitivity;
• arrhythmias ezinzima;
• decompensated ukuhluleka kwenhliziyo;
• yokwehluleka kwesibindi ukusebenza;
• oluhambisana diathesis;
• isisu izilonda, ikakhulukazi nge ukuthambekela ukopha.

Kufanele futhi ukuthi le izidakamizwa ezinqunyiwe ngokuqapha nezingane ezineminyaka engaphansi kweminyaka engu-12 ubudala kanye lactation. Ngaphezu kwalokho, akunakwenzeka ukusebenzisa ejenti ngemithambo yegazi ngesikhathi wokugoqa.

Yokusetshenziswa

"Dipyridamole" - anti-thrombotic izidakamizwa okufanele iqondiswa kuphela udokotela ukuba khona.

Ngokuvamile, amaphilisi kanye amaphilisi athathwa ngomlomo imizuzu 60 ngaphambi kokuba kudliwe, ingilazi yamanzi. Ukuze kuncishiswe umphumela kuyacasula phezu mucosa esiswini izidakamizwa kungenziwa wageza phansi ubisi olufudumele.

Isikali futhi indlela ukusetshenziswa kwezidakamizwa kufanele afakwe kuphela udokotela kuncike eminyakeni yobudala lesiguli, ukufunda kanye nesimo sakhe sempilo.

Ngokuba nokuvimbela thrombosis iqondiswa 75 mg nomuthi izikhathi 6 ngosuku (umthamo sangemihla - 300-450 mg).

Lapho esingamahlalakhona senhliziyo usebenzisa 25-50 mg zomuthi kathathu ngosuku. Umthamo esiphezulu ngalesi isimo - mayelana 150-200 mg.

Ukuze uvimbele ekunqandeni we xhumelela stent kanye nesineke unikezwa 50 mg izidakamizwa (kane ngosuku) kanye acetylsalicylic acid. I nomuthi isetshenziswa ngaphambi kokuhlinzwa, kanye phakathi nesonto ngemva.

Lapho izifo occlusive semithambo yezingalo nemilenze aphansi Kunconywa ukuthatha mg 75 zomuthi kathathu ngosuku.

Umthamo wansuku zonke zomuthi ezinganeni incike isisindo sabo (5-10 mg ngayinye kg).

Ngokusho imiyalelo, ngesikhatsi ukwelashwa kuyadingeka ukuze kukhawulwe ukusetshenziswa itiye nekhofi, njengoba kungenza buthaka amandla umphumela umuthi.

ukweqisa izidakamizwa

Lapho usebenzisa i-ebulilini zomuthi zimpawu ezilandelayo kungenzeka isiguli: ephansi blood pressure, isiyezi, kukhuphuke kwenhliziyo ukopha. Kulokhu, ukumisa izidakamizwa kanye nodokotela.

ukusabela ezingezinhle

Ngokusho izimpendulo iziguli, kwezinye izimo, yokwamukela izimali angabangela side effects elandelayo:

• komzimba;
• palpitations inhliziyo;
• ukwehlisa komfutho wegazi (ikakhulukazi uma iqondiswa ngemithambo yegazi);
• thrombocytopenia;
• ukuphathwa ikhanda;
• iziyaluyalu dyspeptic;
• umsindo ekhanda;
• ngamanzi ebusweni;
• tachycardia;
• ukopha anda noma ukopha.

izidakamizwa ekuhlanganyeleni

umphumela Antiplatelet zomuthi okuthuthukiswa ekuphathweni kanyekanye acetylsalicylic acid, tetracycline, penicillin akuzange kusize, cephalosporin, anticoagulants engaqondile futhi nicotinic acid.

Kufanele kuqashelwe ukuthi le anticoagulants ngokungaqondile, thrombolytics futhi heparin bungase bandise amathuba okuba yezinkinga ukopha.

Asinakusho ukuthi caffeine nasezimisweni xanthine izidakamizwa ukunciphisa vasodilating nemiphumela anti-thrombotic izimali, futhi antacids ukunciphisa ukumuncwa yayo nokwehlisa lokuhlushwa igazi.

Ngokuphathelene ukulungiselela kuchazwe, it kwandisa imiphumela izidakamizwa antihypertensive.

Ngingakwazi ukusebenzisa imithi "Dipyridamole" phakathi nenkathi yokukhulelwa?

Ochwepheshe bathi uma uthatha olucutshungulwayo imali kubantu besifazane abakhulelwe ukuthuthukisa ukuxakeka. Kunalokho, lesi sidakamizwa "Dipyridamole" ngesikhathi sokukhulelwa ngokuvamile enqunyiwe uma kukhona usongo kwesisu ingane noma esingamahlalakhona esinomhlapho.

Amanani kanye analogue

Umuthi ungayithola enye "Dipyridamole"? Analogs izimali ezibalwe ngezansi. Lezi zihlanganisa izidakamizwa ezilandelayo: "Parsedil", "Kurantil", "Padikor", "Antistenokardin", "Trankokord", "angina", "persantin", "Dipyridamole-Verein". Konke lokhu mithi isithako efanayo esebenzayo. Nokho, bangase babe ezahlukene side effects kanye contraindications. Kule ndaba, kutuswa ukusebenzisa lezi zimali kuphela emva kokubonisana udokotela wakho.

Kungakanani buyisidakamizwa "Dipyridamole"? wentengo zokhahlamba kusuka ruble 380-420 (kuye ngokuthi lemali kanye ifomu wokukhulula izidakamizwa).

Izibuyekezo

Ngokuvamile, impendulo yakho mayelana leli thuluzi kusala labo iziguli okwathiwa lomisiwe nokwelashwa ngaphambi kwesikhathi ukuguga esinomhlapho, kanye esingamahlalakhona esinomhlapho.

Kufanele kuqashelwe ukuthi abesifazane abakhulelwe ahlupheke umuthi onjalo kuhle. Bayingcosana wobulili fair kokuba ukusabela ezingezinhle ngendlela ukuncipha komfutho wegazi nesiyezi.