Yini "ibuprofen" (amaphilisi)? "Ibuprofen" - ijeli, amafutha, ukumiswa: imfundo manual, ukubuyekezwa. "Ibuprofen" (isiraphu izingane): yokusetshenziswa

Yini "ibuprofen" ezinqunyiwe iziguli? Lokhu sizokutshela esihlokweni samanje. Kusukela ke uzofunda izindlela wathi senziwa ngayiphi indlela, kanjani futhi kulokho Isikali kumele kuthathwe nokunye.

Ukwakheka, emabhokisini incazelo, izinhlobo zomuthi

kwaveza "ibuprofen" ngayiphi indlela? Yokusetshenziswa, ochwepheshe zangempela ukubika ukuthi lokhu izidakamizwa ikhiqizwa ezihlukahlukene.

• Biconvex amaphilisi round futhi ayatholakala emakhemisi ngo amabhokisi 20, 10 noma izingcezu 100. Sinenkosi surface bushelelezi nomhlophe. Ingqikithi asebenzayo yalesi izidakamizwa ibuprofen.
• Camera "ibuprofen" amaphilisi-mbumbulu. Kusukela lokho lawo amaphilisi, sizokutshela kancane okunye. Zakhiwa esincane element asebenzayo, ngalokho lunikeze isenzo okuqhubekayo.
• Amaphilisi Abonayo. Leli fomu iqukethe 300 mg lomcebo asebenzayo. Bangancibilika kancane kakhulu.
• "Ibuprofen" ukumiswa. Syrup izingane itholakale ukudayiselwa egabheni ngesipuni wokulinganisa. Ukumiswa kuyinto mass homogeneous umbala ophuzi. Kungenzeka, njengoba ukunambitheka orange kanye sitrobheli.
• "Ibuprofen" suppositories. Imiyalelo, ukubuyekezwa bathi lezi amakhandlela asetshenziselwa rectally. Basuke edayiswa amaphakethe of izingcezu 10.
• Aqinile. Leli fomu ukulungiswa isixazululo nomuthi ngoba ukungenisa. Umkhiqizo osuphelile kunobuciko minty futhi iphunga elimnandi.
• "Ibuprofen" 5% wamafutha. Ukusetshenziswa kwalesi thuluzi likuvumela balahle ubuhlungu emisipheni nasemalungeni. Ijeli isetshenziswa ihlelwe ngokulandelana kwezihloko kuphela.
• Isixazululo for umjovo. It is ekhiqizwa eJalimane futhi ithengiswe amakhadibhodi amaphakethe of 4 amaphilisi. Faka izidakamizwa ngemithambo yegazi.

Izici zomuthi

Yini "ibuprofen" isetshenziswa kwezokwelapha? Ngokusho imiyalelo, umuthi eyisidalwa esinenkululeko nonsteroidal eqeda ukuvuvukala. Uyakwazi nethonya eqeda ukuvuvukala, antipyretic nemiphumela analgesic. Ochwepheshe bathi leli thuluzi ngokungakhethi amabhlogo TSOG2 futhi TSOG1.

Umgomo we isinyathelo ka-ibuprofen is ekunqandeni prostaglandin zamagama, okungukuthi, ukuba balamuli ukuvuvukala, ubuhlungu futhi impendulo hyperthermic.

Pharmacokinetics zomuthi

Yiziphi imingcele pharmacokinetic baye "ibuprofen" ithebhulethi? Amafomu ezicelo ka ekwakhiweni temlomo kuqinisekisa ukumuncwa okusezingeni eliphezulu futhi fast kusuka pheshana emathunjini.

I lokuhlushwa eliphezulu kakhulu ibuprofen plasma siyenzeka emva kwemizuzu 120-240 emva abaphathi. Ukuxhumana-plasma amaprotheni ngaphezulu kuka-90% kanye nencenye ukuphila - 2 amahora.

Izidakamizwa "ibuprofen" (Ukumiswa kanye amaphilisi) kancane ingena phakathi kwamalunga. imfuyo yayo asebenzayo egcinwa nezicubu lwamalunga. Lokhu kunikeza ke ne lokuhlala eliphezulu isithako esisebenzayo.

Ngemva ukumuncwa ngu-60% of the ngasebenzi R-ifomu zomuthi uguqulwe esebenzayo S-ukuma.

Lesi sidakamizwa is akheka. Lokukhipha ke nge izinso (akushintshiwe), kanye kanye Bile.

Izinkomba ukusetshenziswa kwanoma iyiphi ifomu zomuthi

Yini "ibuprofen" kungenziwa inikezwa iziguli? Ngokusho imiyalelo, umuthi ine izinkomba ezilandelayo:

• iziyaluyalu umgogodla, neziyaluyalu sokuvuvukala emalungeni (kuhlanganise ankylosing spondylitis, i-rheumatoid arthritis kanye sifo, i-osteoarthritis);
• febrile syndrome, okwenzeka ku isizinda imikhuhlane ezithathelwanayo noma;
• ubuhlungu ngokulinganisela imisuka ehlukahlukene (kuhlanganise ikhanda, neuralgia, migraine, ubuhlungu nasezinkingeni ezilandela ngemva kokuhlinzwa, ubuhlungu yamazinyo, myalgia, isifo sofuba eyinhloko, ubuhlungu ukucindezeleka kwangemva kwenhlekelele).

"Ibuprofen" ingasetshenziswa nganoma yikuphi ukuhleleka okwamanje? Kusukela lokho lawo amaphilisi kuyabekwa iziguli? Odokotela bathi lokhu izidakamizwa ngenkuthalo ukulapha lingaze. He is kahle futhi ngokushesha kunciphisa ukuvuvukala ubuhlungu (ngesikhathi ukusetshenziswa kuphela), kodwa akuphazamisi ukuqhubeka kwesifo.

Izimo

Yini "ibuprofen" lisetshenziswa, iziguli, thina kuchaziwe ngenhla. Ngokuphathelene Izimo ngalesosikhathi they zihlanganisa isiguli esilandelayo:

• erosive nezifo esidalwa yizilonda emathunjini sibe ka ipheshana wokugaya ukudla, ikakhulu esigabeni acute (isib 12 isilonda tiperstnoj amathumbu, isisu, isifo Crohn, izilonda emathunjini, nonspecific);
• hypersensitivity womuntu ukuze izithako ezakha izidakamizwa;
• hypersensitivity isiguli acetylsalicylic acid nezinye ama-NSAID, kuhlanganise nomlando wokwelatjhwa rhinitis, kufanelekile bronchial, urticaria ngemva NSAID noma acetylsalicylic acid;
• ukuvuvukala isifo wamathumbu;
• ngokwengxenye noma ngokugcwele acetylsalicylic acid ukungabekezelelani syndrome (obonakala njengenhlangano rhinosinusitis, urticaria, ama-polyp ku mucosa acinene, isifuba somoya bronchial);
• isikhathi ngemva ukuxhumelela imithambo yenhliziyo ukuhlinzwa dlula;
• oluhambisana diathesis, hemophilia nakwezinye iziyaluyalu ekunqandeni egazini (isib, hypocoagulation);
• ukuhluleka hepatic ezinzima, izifo ezihlukahlukene kwesibindi;
• ukopha intracranial, ukopha emathunjini;
• ezinzima esingamahlalakhona kwezinso, waqinisekisa hyperkalemia;
• okuqhubekayo isifo so-renal.

Yimaphi amanye Izimo zikhona "ibuprofen" izidakamizwa? Syrup izingane is hhayi Kunconywa ukunikeza izingane ngaphansi 3 izinyanga, nezinye izinhlobo imithi - iminyaka 6. Futhi, lo muthi akufanele isetshenziswe ngesikhathi sokukhulelwa.

wamukelekile baqaphe

Kungaphansi kwaziphi izimo kufanele libekwe imithi "ibuprofen" ngokucophelela okukhulu? Isicelo (impendulo mayelana naleli thuluzi izokwethulwa kamuva) zomuthi kwasebekhulile, nabantu ukuhluleka kwenhliziyo, umfutho wegazi ophakeme emithanjeni kanye ischemic isifo senhliziyo kumele uhambisane ncamashi baqashwe ngudokotela wakho.

Futhi ngokucophelela okukhulu banikezwe imithi engabelwe isifo cerebrovascular, dyslipidemia, isifo sikashukela, izifo kwemithambo yegazi (neuropathy), ukubhema, enteritis, utshwala njalo ukusetshenziswa, isifo sokuqina kwesibindi kolwelwesi, nephrotic syndrome, hyperbilirubinemia, nesifo, izifo igazi umsuka engaziwa futhi phakathi webele yokudla.

Izindlela kwesicelo zomuthi

Izindlela Ukusebenzisa izidakamizwa incike buyisiphi ukukhululwa.

• Isiraphu.

Ngayiphi umthamo kuboniswa "ibuprofen" izingane? Iziyalezo yokusetshenziswa uthi, maqondana amaphilisi, isiraphu izenzo ngokushesha okungaka. Ngaphambi kokusebenzisa leli fomu Shake kahle. Umthamo zomuthi kufanele ichaze kuphela udokotela wezingane, kuye ngokuthi isimo lesiguli.

• Amakhandlela.

Suppositories "ibuprofen" ahloselwe ngokukhethekile ukuze izinsana. Zisetshenziswa rectally, futhi beqala ukuthatha isinyathelo emva kwemizuzu engu-30. Lapho imfiva noma ubuhlungu syndrome, umthamo owodwa we-umuthi 5-10 mg ngayinye 1 kg isisindo ingane. Sebenzisa ikhandlela okungcono nge esingaba amahora 6-8.

• Gel, amafutha.

kufanele ngisebenzisa kanjani wamafutha "ibuprofen"? Ijeli strip 1.5 cm lasetshenziswa the lesion massage emnene. Kuyinto ebukekayo ukuze zigweme ukuthintana isidakamizwa nolwelwesi lwamafinyila kanye amanxeba evulekile. Kungenjalo, nomuthi kuyadingeka ngokushesha hashaza ngamanzi afudumele.

• Tablets.

Ingabe "ibuprofen" amaphilisi ziyingozi ezinganeni? Iziyalezo yokusetshenziswa uthi leli fomu zomuthi akuyona efiselekayo ukunikeza izingane kuze iminyaka 6.

Thatha le imithi kufanele kube phakathi ukudla. Ngokuvamile, iqondiswa i inani 5-10 mg ngayinye esisindo 1 kg kathathu ngosuku. Ngakho, umthamo wansuku zonke kumele singeqi 20 mg ngayinye kg.

Ngo-rheumatoid arthritis nezinye izifo ngokuhlanganyela izidakamizwa iqondiswa e isamba 40 mg / kg (kepha hhayi ngaphezulu).

amacala ukweqisa izidakamizwa

Ngezinye ngemithamo ephakeme zomuthi elandelayo izimpawu zingase ukuthuthukisa ezigulini: isicanucanu, ukucobeka, ubuhlungu besisu, ukozela, ukuhlanza, tinnitus, ukucindezeleka lactic umzimba, ikhanda, ukwehluleka oyingozi so-renal, ikhoma, bradycardia, kunciphisa umfutho wegazi, fibrillation atrial Atria, ayeke okumelwe uphefumule futhi ukhulume tachycardia.

Ukwelashwa - esiphuthumayo lavage esiswini (ngaphakathi imizuzu 60 ngemva kokudla), abaphathi amalahle isebenze, futhi ane-alikhali diuresis amanzi.

side effects

Ingabe ukubukeka enqabayo ukusabela izidakamizwa "ibuprofen"? Gel ukusetshenziswa yangaphandle ngeke abangele imiphumela okungafunwa. Ngokuphathelene izinhlobo ngomlomo izidakamizwa, benza kungabangela imiphumela elandelayo:

• Ubuhlungu obukhulu besisu, ukungakuthandi ukudla, isicanucanu, umlomo obuhlungu, ukuhlanza, gingival mucosa ulceration, pyrosis, stomatitis aphthous, uhudo, ukoma noma ukuluma kwesikhumba emlonyeni, ukubuyisa, pancreatitis, ukuqunjelwa;
• ukusha kwesibindi kohlobo;
• bronchospasm, dyspnea
• ukulahlekelwa kukuzwa, umsindo noma enkeneneza ezindlebeni, ukulahlekelwa kukuzwa;
• ukucasuka bese we amehlo, scotoma, izilonda ezinobuthi of emsipheni optic, angaboni kahle double noma angaboni kahle, ukuvuvukala Isivalo kanye conjunctiva;
• ukuqwasha, ikhanda, ukusangana, ukuba nesiyezi, ukudideka, ukukhathazeka, ukucindezeleka, ukucasuka bese ukwethuka, somnolence, ukuyaluza, aseptic meningitis;
• tachycardia, congestive inhliziyo ukwehluleka, umfutho wegazi ophakeme;
• ukwehluleka oyingozi so-renal, polyuria, nephritis nomzimba, nephrotic syndrome, cystitis;
• ukuqubuka, angioedema, pruritus, erythema multiforme anaphylactoid ukusabela, imfiva, anaphylaxis, dyspnea, bronchospasm, Stevens-Johnson syndrome, eosinophilia, epidermal necrolysis anobuthi, rhinitis iguliswa;
• ukujuluka owandiswayo;
• kwegazi, purpura thrombocytopenic, futhi thrombocytopenia, leukopenia, agranulocytosis;
• ulceration ukopha emathunjini.

Kufanele kuphawulwe ukuthi yokwamukela ukulungiselela kungadala izinguquko amagugu laboratory ezilandelayo:

• serum creatinine lokuhlushwa (lenyuke);
• ukopha isikhathi (lenyuke);
• creatinine imvume (incipha);
• lokuhlushwa glucose e serum (encishisiwe);
• elithwala umoya-mpilo noma hematocrit (kungancipha);
• umsebenzi isibindi transaminase (lenyuke).

Ngezinye okuvela ukusabela okunjalo ngokushesha kufanele ayeke ukuthatha izidakamizwa kanye nodokotela.

izincomo ezithile

imithi Ukwelashwa "ibuprofen" kufanele kwenziwe umthamo ubuncane ezokwenza abonise esiphezulu kusebenta zokwelapha. Kulesi Yiqiniso yokwelapha kumele ibe mifisha.

Uma impatho wenziwa isikhathi eside, kudinga ukulawula nezinso isibindi kanye neuropathy igazi isithombe.

Uma izimpawu gastropathy kudinga ukuqapha ngokucophelela isimo lesiguli. Kufanele zihlanganisa nokuqhuba esophagogastroduodenoscopy, kanye fecal okulumba kwegazi futhi ephelele kakhulu segazi (ukunquma hemoglobin).

izidakamizwa ekuhlanganyeleni

Kuyinto engathandeki ukulungiselela elihlangene "ibuprofen" ungabuqeda nge aspirin nezinye ama-NSAID. Lokhu kungenxa yokuthi kungase kuncishiswe imiphumela ukuvuvukala futhi antiplatelet kwala magciwane.

Ngesikhathi esifanayo ukuthatha izidakamizwa kokubuyekezwa nezidakamizwa thrombolytic futhi anticoagulant kwandisa ingozi ebangela ukopha.

"Tsefaperazon", "Tsefamandol" valproic acid "tsefotetan" futhi "plikamitsin" kwandisa amathuba wokuthuthukisa gipoprotrombinemii.

Izidakamizwa ukuthi uvimbele uketshezi ijabulise, ukunciphisa excretion futhi ukwandisa plasma lokuhlushwa "ibuprofen".

nomuthi Okubukwe elilulaza isinyathelo ejenti uricosuric, sithuthukisa imithelela anticoagulants, fibrinolytics namanxusa antiplatelet.

Imithi yeziguli

Izidakamizwa "ibuprofen" kuthandwa kakhulu ezigulini. ukuma kwalo njengoba ephumelela kakhulu ejenti eqeda ukuvuvukala ukuthi has ezihlukahlukene izinhlobo ukukhululwa.

Ngokusho izimpendulo iziguli, imithi liqala ukwenza izinto ngokushesha okukhulu. Akhipha ngisho nobuhlungu obukhulu kakhulu amalunga nemisipha, futhi aqede izinhlungu zekhanda kanye ukuvuvukala imisuka ehlukahlukene.

I ethile kuphela lokhu imithi inombolo enkulu yemiphumela emibi kanye contraindications. Ngokusho izimpendulo iziguli, "ibuprofen" izidakamizwa bavame ukubanga esiswini izinhlungu, isicanucanu, isiyezi ukuphalaza nokukhishwa iba imbangela izilonda futhi erosions kule ipheshana wokugaya ukudla. Ngakho-ke, zisebenzise lokhu izidakamizwa ngesikhathi esincane umthamo Kunconywa futhi isikhathi esifushane. Okuwukuphela kwendlela uyokwazi ukuqeda ubuhlungu futhi engazizwa yini imiphumela emibi.