Uyini isikhathi prothrombin, futhi iziphi izimiso zayo?

Prothrombin isikhathi, izinga okuyinto abadala imizuzwana 11-15, futhi izingane - 13-18 imizuzwana, zingandiswa, iba uphawu khona zonke izinhlobo zezifo. Lesi sibalo ejwayelekile ye I neyesi-II plasma isibonisi homeostasis wabiza prothrombin umsebenzi eziyinkimbinkimbi.

Uma isikhathi prothrombin uqala ukwandisa, kubonisa ukuthambekela hypercoagulability. Lokhu kungaba nezizathu ezimbalwa:

· Uma eziyinkimbinkimbi prothrombin ihlangabezana ukwahluleka ukuthuthukiswa coagulopathy njengoba gipoprokonvertinemiya futhi hypoprothrombinemia.

· Ngezinye izikhathi, lesi sibalo anda khona amyloidosis, okuyinto kubangelwa ukuntula isici X. Kulokhu, it is amuncwa amyloid. Uma nephrotic syndrome, khona-ke ukwehluleka izici VI futhi V

Kusukela zamagama izakhi prothrombin eziyinkimbinkimbi kwenzeka esibindini, ngoba akunampilo uma inombolo zabo ziye zancipha. Kwezinye izimo, isikhathi prothrombin kuyinto inkomba isimo bokuphila emzimbeni.

Ukwanda kule Inkomba siyenzeka futhi khona-hepatitis oyingozi futhi ezingalapheki, isifo sokuqina kwesibindi kanye inqobo sokuwohloka subacute hepatic nezinye izilonda parenchyma isibindi. Iqiniso lokuthi lezi zinguquko kuwuphawu olubi ngifakaza ekuthuthukiseni yisiphi isifo. Uma kutholakale ukuthi une-jaundice, prothrombin isikhathi kungase kwandise ngenxa yokuthi inani Bile emathunjini kuyehla, okuholela malabsorption vitamin K. Nguye oye bahileleke synthesis prothrombin eziyinkimbinkimbi.

Futhi phakathi kwezimbangela ezibangela i ukwanda kwalesi ipharamitha, ngokuthi enteropathy futhi dysbacterioses emathunjini okuholela ukuntula ezingamahlalakhona vitamin K. Uma impatho Kwenziwa usebenzisa abaphikisi we Vitamin, abahlukaniswe kokuqeda sinyathelo synthesis izizathu eziyinhloko eyinkimbinkimbi prothrombin. Kukholakala ukuthi ukusetshenziswa coagulants ingaqhutshezwa uma isikhathi prothrombin ngokuphindwe kabili.

Kunemithi eminingi ekwazi ukwandisa sikhathi Uhlaka Inkomba. Phakathi kwabo kukhona laxatives, imithi elwa namagciwane, i-aspirin (enikeziwe ukusetshenziswa ebulilini) kanye quinine Ama-anabolic steroid.

Ngokuvamile, iziyaluyalu kwesibindi prothrombin time Inkomba ivame ukwandisa. Ngakho-ke, uma kukhona uhlobo isifo, kubalulekile ukuqapha le nkomba.

Ngezinye izikhathi kunezimo lapho isikhathi prothrombin iqala ukuze wehlise. Lokhu kubonisa ukuthi kukhona ukuthambekela hypercoagulability. Kwesinye isikhathi sengathi kwenzeka emabangeni kokuqala thrombosis e nemilenze ephansi, futhi polycythemia. Isikhathi esining impela, ingxenye kungenzeka yehliswe ngama sokukhulelwa sekwephuzile noma ngemva ukusetshenziswa kwezidakamizwa ezithile, njenge acetylsalicylic acid (ngemithamo emincane) merkaproturina kanye nezindlela zokuvimbela ukukhulelwa ngomlomo.

Lapho ehlolwa ngoba ngomlomo yokwelapha coagulation, isikhathi prothrombin uphenyo njalo. Nokho, endaweni enjalo ushintsho isimo Inkomba kungahle kubangelwe isetshenziswa thromboplastin, edingekayo kuleli cala. Ngoba kubalulekile ucwaningo ngemuva kokusebenzisa izinhlobo ezahlukene thromboplastins. It is njengelinye lamazwe imisebenzi ebaluleke kakhulu imithi ezisebenzayo. Isiguli oneminyaka engaphansi observation, ukuhlaziywa kumele ngenjwayelo ngemva kokubekwa esikhundleni umuthi omusha.