Thyroglobulin - kuyini? Kuyini izinga thyroglobulin?

Njalo umuntu uhlushwa yegilo ukungasebenzi noma ukuhlolwa i endocrinology izifo sokuhlasela kwamasosha omzimba esolwa wayebhekene isidingo ukuba unikele ngegazi ukuze thyroglobulin. Yini-ke liwukuthi, akubona bonke odokotela ukuchaza. Ngakho-ke, abantu baqala ukubheka ulwazi ku-intanethi noma nabangani. Futhi ngokuvamile kuholela nezimo ezicindezelayo, ngenxa yokuthi, ngokusho eziningi, ukwenza thyroglobulin kokuhlahlela umdlavuza okusolwayo. Kodwa lokhu akulona njalo kunjalo. Ngakho-ke, labo ababhekene nezimo isidingo ucwaningo esinjalo, kubalulekile ukuthola konke mayelana thyroglobulin. Kuyini, ungacela udokotela wakho noma ezinye Ochwepheshe. Lokhu kubalulekile ikakhulukazi kwabesifazane, ngoba maningi amathuba okuthi ukuphazamiseka kwama-hormone.

Kuyini thyroglobulin?

Ukulawulwa kwendlala yegilo indlala emelelwa ekuqongeleleni zokwakheka encane eyindilinga - follicle. Ngaphakathi kuwo kukhona ngobuningi samanje amaprotheni thyroglobulin. Yini it is yilabo baphazamise ukukhiqizwa eyaziwa hormone. Phela, lokhu amaprotheni luyisisekelo umkhiqizo wabo. Kudlulwa amaseli wendlala yabesilisa, thyroglobulin ezidabula molecule tyrosine, futhi athomu e-iodine ngayinye. etholwe Ngakho-thyroxine. Lokhu amaprotheni - a glycoprotein nge high isisindo yamangqamuzana - kungaqinisekisa ekukhiqizweni kwama-hormone egilo eziyisisekelo amasonto amabili. Futhi kuvela ukuthi kuba - uhlobo ifomu isitoreji, okuyindawo zikhishwa njengoba kudingeka. Akubona bonke iziguli ebekiwe yokuhlola hormone, ungakwazi ukuphendula umbuzo: thyroglobulin - kuyini? Ngo abesifazane, ucwaningo olunjalo kwenziwa kaningi ngoba ziyashesha kakhulu ukuphazamiseka ama-hormone egilo ukungasebenzi.

Amasosha Omzimba ukuze thyroglobulin

Lokho akuyona laziwe kubo bonke. Kwezinye yezifo indlala yegilo kungaba kukhulu kangangokuba sokuhlasela kwamasosha omzimba zomzimba. Ngesikhathi esifanayo yephula synthesis-hormone, ngoba amasosha omzimba ukubhubhisa thyroglobulin. Kuyini lokhu? Lokhu kuyindlela yemvelo yokusabela lapho ocacile wesimiso somzimba sokuzivikela, okuyinto ngosizo amaseli akhethekile ebhubhisa amaprotheni, bamyisa i-elementi alien. Ngenxa yalokho, umuntu akanalo hormone yegilo. Ngokuvamile izimpawu ezifana ubuthakathaka, ukukhathala, ukwehla kwesisindo somzimba abonisa ngakho. Bese iqondiswa yokuhlola amasosha thyroglobulin. Lokhu kwenziwa ngisho khona izifo ukuthi kwandisa ingozi yokungenwa yegilo ukungasebenzi:

- Down Syndrome;

- insulini ancike ngifundise ngesifo sikashukela;

- rheumatoid arthritis;

- anaemia hemolytic.

Ngaphezu kwalokho, ukutadisha ngale ndlela kufanele kwenziwe kwabesifazane abakhulelwe nezifo sokuhlasela kwamasosha omzimba ekutholweni izimbangela ukungazali kanye ukuhlonza amaqembu ingozi phakathi izingane zomama ube endocrine iziyaluyalu.

Uthola igazi

Lokhu namaprotheni ikakhulu ise follicle we indlala yegilo. Kuphela izinto eziningi ezincane kakhulu adedelwa thyroglobulin igazi. Norma ke kuncike ezintweni eziningi, futhi wonke umuntu lihlukile. Inombolo thyroglobulin kunqunywa ubukhulu indlala yegilo, umsebenzi ukusebenza kwawo kanye nesidingo amahomoni umzimba. Kodwa kukhona imikhawulo ethile, nangale elibonisa ngeziphambeko ukusebenza indlala yegilo. Lokhu kwenzeka ngokuvamile kakhulu ekubhubhiseni amaseli ayo kubangelwa izinqubo ukuvuvukala noma izimbangela zangaphandle. Ngakho-ke akuvamile ukucela nesilinganiso thyroglobulin. Kuyinsakavukela kwayo okuqukethwe egazini akuyona ezingaphezu kuka-50 ng / ml. Uhlaziyo ongabonisa inkulu kangakanani yegilo indlala ukuthi isebenza kanjani ngenkuthalo nokuthi kukhona ukuvuvukala kuwo. Ezimweni eziningi, lapho kutadishwa ezingeni thyroglobulin kubaluleke kabi, hhayi inani egazini, futhi isikhulumi, okungukuthi, ukwanda noma linciphe ngokuhamba kwesikhathi.

Izinkomba for ukuhlaziya

Ngezinye izikhathi kukhona yokuthi odokotela ngokungadingekile linqume ukuhlolwa kwegazi ukuze thyroglobulin. Kuyini, abazi zonke iziguli, futhi abaningi, azihlole liyesabisa. Kodwa ngaso sonke isikhathi kwenziwa amacala umdlavuza okusolwayo. Yilabo kuphela ezigulini eziye isuswe indlala yegilo, ababoniswe nesifundo esinjalo zikhathi zonke ukuvimbela Ukuphinda. Ngaphezu kwalokho, ukwenza ukuhlaziywa thyroglobulin, futhi labo belashwa iodine enemisebe, ukuqapha ukusebenza yokwelapha. Yabela ke kwezinye Kwezinye izimo:

- ukufunda ukuthuthukiswa hyperthyroidism azalwa naso ezinganeni;

- ukuqapha intuthuko thyroiditis;

- in a Ucwaningo olunzulu ukuntula iodine;

- ukubala ukuphumelela ukwelashwa ngoba i-hyperthyroidism.

Kanjani ukuba bahlolelwe?

- Igazi amasampuli kwenziwa kusukela umthambo ekuseni esiswini esingenalutho. Kungcono yini ukuthi kuke kwaba kusihlwa, ungabhemi, ukuqeda ukuzivocavoca futhi ugweme izimo ezibangela ukucindezeleka.

- Ukuze uthole imiphumela olunembile, futhi kufanele lihlaziya anti-thyroglobulin. Kuyini lokhu? Kuyinto i omzimba ukuba iprotheni alibulale. Uma eziningi kubo, ezingeni thyroglobulin egazini liphansi.

- kusasele amasonto amathathu ngaphambi blood donation kuyadingeka ukuze ayeke ngemithi equkethe thyroxine nezinye ama-hormone.

- Ukuhlaziya ekutholweni ukubuyela ngokuphelele ekubhemeni lomdlavuza ukwenza ngemuva ngaphambili kuka izinyanga ezintathu ukuhlinzwa nezinyanga eziyisithupha ngemuva kokusebenzisa iodine enemisebe.

Thyroglobulin anda - kusho ukuthini?

Uma igazi ulahlwa ngaphandle eziningi lokhu amaprotheni, kungase kube nemiphumela yokuchitheka amaseli yegilo. Lokhu kungenzeka ngoba endocrine ezihlukahlukene nezifo sokuhlasela kwamasosha omzimba. Ngakho-ke, thyroglobulin isigqugquzeli ibonisa ukuthi nangesineke kungase kube:

- thyroiditis;

- Graves 'disease ivame;

- Graves 'disease ivame ;

- adenoma ingozi;

- ubovu ukuvuvukala indlala yegilo;

- yezinkinga emva kokuhlinzwa, biopsy we indlala yegilo noma ukuhlukumezeka;

- ukubhujiswa yegilo amaseli nangenxa yezinye izizathu.

Futhi, ukwandisa ezingeni le amaprotheni egazini, ngemva kokusebenzisa iodine enemisebe e-ukuxilongwa kanye nokwelashwa izimila. Kancane aphakeme thyroglobulin ezingeni njengoba iziguli ezine-Down syndrome, in iziguli ezinzima ukungakhuli hepatic noma ngesikhathi sokukhulelwa.

Lokhu kungaphazamisa imiphumela yokuhlolwa?

Ngo Imiphumela kakhulu amanga lwembula ukuba khona amasosha thyroglobulin. Ngakho-ke, ukuba khona kwabo futhi kuyadingeka ukuze abone. Kungaba kuthinte Imiphumela izidakamizwa hormone, amalungiselelo iodine, khona izifo ezithathelwanayo noma yofuzo. Ngaphezu kwalokho, ukuhlaziya kungenzeka alithembekile ngenxa ukuchayeka ngokuqhubekayo emisebeni noma khona ubuthi egazini. Ngisho eziningi ukucindezeleka kungathinta ezingeni thyroglobulin, kanye namasosha omzimba ke. I lokuhlushwa lokhu amaprotheni kwandisa ngesikhathi sokukhulelwa futhi abesifazane kakhulu eminyakeni yokuguga. A zokuvimbela inzalo temlomo kwandisa omzimba ukuba thyroglobulin. Iphinde kungathinta imiphumela yokuhlaziya.

Ingabe thyroglobulin oncomarker?

Eziningi zalezi ziguli akazange achaze ukuthi kungani ukuhlaziywa kwenziwa, baphendukele imithombo inthanethi. Ayathanda umbuzo: thyroglobulin anda - kusho ukuthini? ngokuvamile bathola impendulo okungalungile, okuholela ukucindezeleka okunzima. Empeleni, abanye bakholelwa ukuthi imithombo thyroglobulin kuyinto oncomarker futhi level yayo anda kubonisa ingozi yomdlavuza.

Kodwa eqinisweni akusiyo. Ngokuvamile, lokhu ukuhlaziywa kwenziwa ngemva kokususwa indlala yegilo ukulawula kumiswa metastases. Ngemva thyroglobulin kungenziwa elakhiwe hhayi kuphela indlala, kodwa futhi umdlavuza. Ngakho-ke oncomarker lokhu amaprotheni kuba kuphela ukungabi khona indlala yegilo. Iziguli ezinjalo ngemva yokwelashwa okuphumelelayo yomdlavuza ihlaziye ngoba thyroglobulin izikhathi eziningana ngonyaka. Okuwukuphela kwendlela ukucacisa Ukuphinda lesi sifo. Kodwa isimila eyinhloko ngaleyo ndlela akunqunywa, kusukela ezingeni amaprotheni ebukhoneni isebenze yegilo ayihlobene ne ukuthuthukiswa isimila.