Phosphatase ane-alikhali: sivamile abesifazane, amadoda kanye nezingane. phosphatase ane-alikhali egazini: kuyinsakavukela kanye nokusuka

phosphatase ane-alikhali kuyinto-enzyme ethile, elingelakwaJuda iqembu hydrolases. Lokhu enzyme kungabonakala nasemkhakheni zonke izingxenye zomzimba womuntu.

Ikakhulukazi basakaza enzyme asebenzayo osteoblasts, emathunjini mucosa igobolondo, e indlala mammary, yi-placenta, Bile Amapayipi ezindongeni.

Izinhlobo phosphatase ane-alikhali

Phosphatase ihlukaniswe izinhlobo eziningana:
- esinomhlapho;
- izinso;
- isibindi;
- E .;
- amathambo.

phosphatase ane-alikhali, kanye zonke enzyme efana ke, kudingeka kudlule ezihlukahlukene zamakhemikhali ngaphakathi emzimbeni womuntu. Kuyadingeka inani lemali elincane phosphatase ane-alikhali ukwenza zindlela zokusabela. Futhi uma umzimba unazo ukwephula, kungasho ukuthi phosphatase ane-alikhali anda. Izizathu ukwanda kwalesi enzyme zingase zihluke kakhulu.

Kanjani ane-alikhali phosphatase

Lokhu enzyme ayisebenzisa ngayo defosfolirovaniya ukuphendula. Cishe le ndlela yokusabela esakhiwa ngo cleavage kwe-phosphate kusuka izinto eziphilayo eba mangqamuzana. phosphatase ane-alikhali egazini has a lokuhlushwa ezithile njalo. Enzyme uyakwazi ngokudlulisela phosphorus ngokusebenzisa ulwelwesi cell. Ngaphezu kwalokho, phosphatase - elithile kwezinkambiso-calcium-phosphorus umzimba. Umsebenzi kunazozonke enzyme ibizwa kuboniswe pH naphakathi ububanzi 8,6-10,1. Kungakho igama - kuyinto ane-alikhali.

phosphatase ane-alikhali egazini

Ububanzi izinkomba amazinga evamile igazi phosphatase ane-alikhali sasivumela ububanzi. Isifundo ziyahlukahluka kusuka 44 IU / L ukuze 147 IU / L. Akufanele yini ngokushesha netwetwe uma ane-alikhali phosphatase anda. Kungenzeka kungenangozi ngokuphelele izizathu. Ngokwesibonelo, izinga kwabesifazane abazithwele ngokuvamile kancane overstated. Wabuye overestimated nentsha, abavule esiteji nezingokomzwelo zokuthomba. Konke lokhu kungenxa ukukhula umzanyana bone, futhi akubonisi ezihlukahlukene kwezinso emzimbeni womuntu. Futhi ukuthola phosphatase incike yobudala kanye ocansini yomuntu.
Okwamanje akukho indlela okwakha, ngakho ukushintshashintsha nemingcele Norm incike reagents ezisetshenziswa endaweni yokucwaninga ukuze kwenziwe ucwaningo.

phosphatase ane-alikhali. kuyinsakavukela

Omunye khetho sokunquma kwezinso emzimbeni kuyinto phosphatase ane-alikhali. Sivamile abesifazane, amadoda kanye nezingane kancane ezahlukene, kufanele kuphawulwe. Izinga le-enzyme emzimbeni kwabesifazane kuyinto kancane singaphansi kwesilinganiso for amadoda. Nakuba izingane inkomba ezingeni le enzayimu kuningi kunokomuntu kwabadala.

Izinga ejwayelekile phosphatase ane-alikhali e oketshezini olungenambala lwegazi we ingane:

- ezinsaneni: 245-255 IU / L;
- ezinganeni ezineminyaka engu-1 kuya eminyakeni 9: 345-355 U / L;
- ezinganeni ezineminyaka 10 iminyaka engu-15: 275-285 U / L;
- intsha, yobudala engu-16 kuya ku-19: 145-155 U / L.

Sivamile amadoda:

iminyaka engu-21 kuya ku-30 -: 100-110 U / L;
- abaneminyaka ephakathi kwengu-30 kuya ku-45: 110-120 U / L;
- abaneminyaka ephakathi kwengu-46 kuya ku-54: 120-130 U / L;
- abaneminyaka ephakathi kwengu-55 kuya ku-70: 135-145 U / L;
- abangaphezu kweminyaka engu-iminyaka engu-71: 180-190 U / L.

Kubantu abadala, lokhu kuncike phansi, kancane ezahlukene ane-alikhali phosphatase.

Sivamile kwabesifazane:

iminyaka engu-21 kuya ku-30 -: 80-90 U / L;
- abaneminyaka ephakathi kwengu-30 kuya ku-45: 90-100 U / L;
- abaneminyaka ephakathi kwengu-46 kuya ku-54: 105-115 U / L;
- abaneminyaka ephakathi kwengu-55 kuya ku-70: 125-135 U / L;
- engu-'71: 155 -165ed / l;

It lingahunyushwa baphetha ukuthi amadoda ngokuphathelene izibalo zabesifazane, kancane ephakeme ane-alikhali phosphatase. Sivamile abesifazane lingaphansi kuka izinga zabesilisa labangaba ngu-20 U / L.

Izizathu enanini eliphakeme phosphatase ane-alikhali

Kuye kwathiwa, lapho kuncike le phosphatase ane-alikhali. Norma luyanda, futhi lokhu kungenzeka ingozi empilweni. Kodwa kwenzeka futhi okuphambene nalokho, lapho ukwanda kwe-Inkomba isixwayiso kuqala futhi olunembile ukuthi emzimbeni wesiguli kuyagcinwa ukwephulwa abalulekile.

On ukwanda ukubika enzyme kungathinta:

On the ingxenye yaleli pheshana biliary futhi isibindi:

- isimila we imbobo Bile;
- jaundice, okungase kubangele isimiso we Amapayipi Bile;
- nomdlavuza wesibindi;
- nezibazi we Amapayipi Bile, cuphuluza izinqubo kuhlinzwa;
- ematje lamabili Amapayipi Bile;
- umdlavuza isisu noma amanyikwe;
- isifo sokusha;
- mononucleosis ezithathelwanayo;
- yimuphi umsuka kwesibindi. Kulesi sifo mayelana 3-nesibaya anda phosphatase ane-alikhali.

Izizathu phezu ingxenye ithambo ethintekile:

- isifo Paget sika. Lesi sifo libhekene normal bone ukukhula, kanye ukuphazamiseka ezindaweni ezithile isakhiwo ithambo. Kulesi isifo, kukhona amazinga aphezulu kakhulu enzyme olucutshungulwayo;
- amathambo isimila;
- osteosarcoma, okuyinto isimila esibulalayo ku ithambo;
- osteomalacia cuphuluza calcium ukuntula (osteomalacia).

Ezinye izizathu:

- isilethikusebenza;
- hyperparathyroidism, okuyinto isifo hormone, uma waphawula ngokweqile hormone parathyroid, parathyroid kwakhiwa. Ngenxa yalokho-ke is leaching-calcium kusukela amathambo;
- perforation emathunjini (ngokusebenzisa-umonakalo);
- izilonda emathunjini.

Izizathu amazinga aphansi phosphatase ane-alikhali

It akubhekwa njalo ukuphambuka liphakeme ane-alikhali phosphatase. Sivamile abesifazane futhi amadoda angase athambekele washintsha futhi phansi.

A amazinga ukuwa phosphatase kungathinta:

- ukumpontshelwa igazi ngemithamo ezinkulu;
- anaemia e ezinzima;
- i-hypothyroidism (ongaphakeme yegilo umsebenzi);
- gipofostataziya (azalwa naso isifo ezingavamile ukuthi kubangela ukuthambisa amathambo);
- amanani enganele zinc kanye magnesium emzimbeni;
- ukwehluleka umzanyana (kwabesifazane abakhulelwe).

Yini kuthinta umphumela

Ukuze wandise:

- Phakathi nenkathi yokukhulelwa, placenta iqukethe phosphatase ane-alikhali. Sivamile abesifazane kule nkathi akubhekwa ngokweqile;
- emva waphuka Uphawula i likhuphuke ka phosphatase ane-alikhali;
- kusukela izingane nentsha kuye kwaba nokwanda okusheshayo kwenani amathambo, ngesilinganiso enzyme anda ezingeni ingxoxo;
- ukwandisa ezingeni phosphatase egazini kungaba, futhi ezinye izidakamizwa, njengokuthi "paracetamol", "ukuphuza ama-aspirin", "Allopurinol", imithi elwa namagciwane ahlukahlukene, futhi ezihlukahlukene neminye imithi;
- Idatha enzyme defosfolirovaniya ezingeni ephakeme kungabonakala nasemkhakheni, ngemva Ukuphola, ezithathwe ukuhlolwa igazi.

On ukwehlisa izinga lokhu enzyme kungathinta zokuvimbela inzalo ngomlomo.

Ukuhlaziywa for phosphatase ane-alikhali

Ngesikhathi ukuthatha ukuhlaziya phosphatase ane-alikhali egazini ukuze serum lokuthi add reagents ethize basabela phosphatase. Khona-ke, usebenzisa izindlela ngqo, lokuhlushwa imikhiqizo etholakale kukalwa. Ngo izicubu ngamunye, kungaba emathunjini, isibindi noma yi-placenta, iqukethe uhlobo oluthile phosphatase ane-alikhali. Phakathi ukuhlaziya emakamu elinganisiwe of enzyme ethize.

Ukuze nginikeze ukuhlaziywa isampula yegazi ukuze enzyme, isiguli kuzodingeka emva kwamaminithi ambalwa. Kwezinye izimo, abantu babe esiswini emva kokudla ekhiqizwa kakhulu ane-alikhali phosphatase. Kulokhu, kungenzeka imiphumela ukuhlaziywa uhlanekezelwe. Ngakho-ke, isiguli awukwazi ukuthatha ukudla noma uphuze amanzi ngaphambi kokubeletha yokuhlaziya.

Ngenxa izindlela laboratory yesimanje, imiphumela yokuhlolwa uzolunga ngemuva kwamahora ambalwa.

Kususelwa yonke idatha, singaphetha ngokuthi esiphansi phosphatase ane-alikhali egazini - kuyinsakavukela. Ukwandisa izinga lokhu enzyme may njengoba isixwayiso iyiphi ngeziphambeko noma ukwephula, futhi ngokuphelele ukuthi asikho isizathu sokukhathazeka. Kunoma ikuphi, le akuyona inkomba lokugcina izinguquko emzimbeni womuntu.