"Ospamoks": imfundo. Ukubuyekeza, intengo izinkomba ukusetshenziswa

"Ospamoks" - okwelapha imfuyo asebenzayo elwa namagciwane kuyinto amoxicillin - Abamele aminopenicillins eziningana. Kwemiqondo phakathi nekhulu lama-20, amoxicillin isibe omunye ethandwa kakhulu ejenti elwa namagciwane. Ngenxa yenani elincane imiphumela emibi noma elimazayo, kodwa futhi ngenxa isinyathelo amagciwane it is ngokuqinile waqinisa ku umtholampilo. Ngo ukuthengiswa "amoxicillin" izidakamizwa engena ngonyaka 1972, futhi njengoba nje kuba-antibiotic eziyisisekelo ekwelapheni yamaphaphu webhaktheriya nezifo zokuphefumula nokusekelwa ukugeleza yabo ngokulinganisela futhi esinzima.

Isimiso Sokuthungatha izici umkhiqizo

Lapho belungela ukuya khona "Ospamoks" ukusetshenziswa kabanzi ngenxa timphawu letibalulekile ketshezi izidakamizwa - amoxicillin. Esikhathini ngezigaba izidakamizwa, enikezwa njengendlela-antibiotic beta-lactam Lokudabuka semisynthetic. It aminopenicillin nge spectrum ebanzi umsebenzi elwa namagciwane, maqondana macroorganism ephephile.

Lapho belungela ukuya khona "Ospamoks" kukhona iqembu ekilasini nozakwabo okuqondene aminopenicillins isigaba ingibitorzaschischennyh. Kuyinto imithi elwa namagciwane ukuthi kusebenze kakhulu abamagama kanje: "Amoxicillin-clavulanate," "Ampicillin sulbactam". Futhi atholakale yonke indawo, kodwa zisetshenziselwa kabanzi okuningi. Inzuzo enkulu usebenzisa amoxicillin, abasusa ethile ngendlela ebaluleke kakhulu - nozwela penicillins.

Umsebenzi elwa namagciwane izidakamizwa

Ukulungiselela "Ospamoks" (izingane kanye nabantu abadala) kunikeza zamagama yamangqamuzana isakhi webhaktheriya cell udonga (peptidoglycan), kokuba isinyathelo amagciwane esitokisini amagciwane abe nenkani. Ngenxa yalokho, lo muthi izidakamizwa "amoxicillin" Ubumpofu bubulala amagciwane. Lapho nomuthi asebenzayo ikakhulukazi ngokumelene amagciwane Gram-HIV: pneumococcus, enterococcus, Listeria. Futhi, lesi sidakamizwa "Ospamoks 1000" iyasebenza emelene anaerobic amagciwane - Clostridium sporogenous futhi peptostreptokokki.

Ngenxa isinyathelo amagciwane futhi ukwephula izinqubo synthesis peptidoglycan "Amoxicillin" kuyinto izidakamizwa ezibanzi-bohlu. Njengoba peptidoglycan njengoba isici kwesakhiwo iseli ampofu udonga amagciwane Gram-negative ngokumelene lapho izidakamizwa futhi esebenzayo. I Lesi sifo siphatha kakhulu ukuba umphumela amagciwane of "Ospamoksa" Helicobacter, Neisseria, okubangela meningitis, salmonella kanye spore ukwakha. Kancane kancane ekuthonyweni amoxicillin hemophilia, Proteus, E. coli, spore ukwakha Shigella, Vibrio cholerae futhi Neisseria esibangela isipatsholo.

Izinhlobo eziyinhloko izifo ukuthi iphathwa lesi sidakamizwa "Ospamoks" kuyinto iqembu pathologies zokuphefumula esithathelanayo imvelaphi virus. Futhi, amabhaktheriya ezibangela acute otitis abezindaba, yebhaktheriya, iphaphu ukugeleza futhi sinusitis zidinga uya khona "Amoxicillin". Lesi sidakamizwa kufakwe kulombhalo ternary ka wokuqeda Helicobacter pylori futhi isetshenziswa izifo enteric, izifo ezibangelwa amagciwane kohlelo genitourinary.

izinkomba

Njengoba unamathele izidakamizwa "Ospamoks 500" manual liqukethe ulwazi mayelana nokusetshenziswa prophylactic. Ikakhulukazi, ukuze kuvikelwe yezinkinga ezibangelwa amagciwane emva kokwenza koda izindlela zokuxilonga imithi zingafundwa e omdala 500 mg 3 izikhathi ngosuku izinsuku 5-7. Igama prophylaxis efanayo ifakiwe futhi ukuvimbela bacteremia ngemva isizinda kwamazinyo. Ibanga izinkomba kanje:

• Ari: webhaktheriya pharyngitis, namathansela, laryngitis, ukucinana kwemigudu yokuphefumula, inyumoniya, iphaphu ukugeleza;
• pustular tesikhumba: amathumba, carbuncles, pyoderma, streptoderma;
• obenesifo ephansi ngomgudu womchamo (cystitis, urethritis);
• ukutheleleka chlamydial lapho ukhulelwe;
• isipatsholo;
• typhoid fever, isifo saseLyme.

Pharmacodynamic nomkhawulo isicelo

I izinkomba ngenhla zilinganiselwe, futhi ezimweni eziningi, uma sicabangela ngamagciwane amelana nemithi, izidakamizwa has awakuthinti. It ayikwazi ukusetshenziswa ngoba impatho angawodwa pneumonia, pyelonephritis, izifo ukonakala we isikhumba nezicubu esithambile. Okwamanje, bonke izidakamizwa aminopenicillins kubhujiswa beta-lactamases amagciwane ngenkuthalo Limiselelwe kuhlanganiswe penicillins evikelwe: "Amoxicillin-clavulanate" futhi imithi ejwayelekile yayo.

Ukuze "amoxicillin" futhi, ngokufanelekile, ukulungiswa "Ospamoks" imfundo eshiya izicelo ezimbalwa kuphela. He is izidakamizwa lokuqala umugqa ezinganeni okhulelwe izifo okungenhla. Futhi, "Amoxicillin" futhi izinguqulo yayo ejwayelekile, okuhlanganisa "Ospamoks", ingasetshenziswa nganoma isiphi yobudala izingane zakho ngokweseluleko lobufakazi. Sebenzisa ngaphandle kwezifo ezithathelwanayo njengoba isilinganiso tekuvimbela izingane ayibalulekile esiwusizo futhi is contraindicated.

Khipha ifomu kanye umthamo

ekwakhiweni okuyisisekelo "Ospamoks" ukulungiselela - amaphilisi equkethe 500 futhi 1000 mg isithako esisebenzayo. Lena ngokuvamile ezisetshenziswa kukho imithi elwa namagciwane ukuthi kuyinto kwemisebenzi yoMnyango abadala. izidakamizwa okusebenzayo kusukela izibhebhe esiswini ohlakaziwe futhi angena igazi. Kokuqhubeka ezicutshini elikhanyayo futhi engena isikhala interstitial abulale ngqo amagciwane, kuyashesha inqubo yokutakula izifo ezithathelwanayo. Futhi iyatholakala ku powder ukwakhiwa ukusetshenziswa ezingane (ngezansi).

Powder "Ospamoks" ngoba ukumiswa

Futhi, uma sicabangela ukuphepha aminopenicillins ezinganeni ukwakhiwa ezingane etholakalayo "Ospamoks" izidakamizwa. Ukumiswa izingane - kuyindlela enhle kwesicelo zomuthi, okuyinto akudingi amaphilisi ukugwinya noma amaphilisi. Lapho ngineminyaka engu-iminyaka engu-5, futhi ngezinye izikhathi-8, izingane unenkinga singagwinyi Isikali okuqinile amafomu. Ukumiswa kulokhu iyona efaneleka kakhulu indlela abaphathi enteral i izidakamizwa elwa namagciwane.

Ilungiselela ekumisweni indinganiso oluyimpuphu umthamo amafomu equkethe 125, 250 kanye 500 mg ngayinye 5 ml ingxube lelungiselelwe. Ejwayelekile womkhiqizo futhi iza ntathu isitsha 60 ml (noma 100 ml i-umthamo 500 mg / 5 ml) ekulinganiseni spoon, ephethe namandla 5 ml.

Izici kanye nezicelo nokushintsha kokudla nokufakwa

Njengoba unamathele izidakamizwa "Ospamoks" imfundo kuhilela izindlela eziningana nokushintsha kokudla nokufakwa incike yobudala futhi umsebenzi kwezinso in iziguli izifo nephrotic. Isikali Adult (engaphezu kwengu-16) kuyinto 1.5-2 g ngosuku. Izibhebhe dispersible ka mg 500 ezithathwe kathathu ngelanga, 1000 mg - izikhathi 2 ngosuku izinsuku 5-7.

Lapho eneminyaka engu-12 eminyakeni engu-16 Kunconywa umthamo 1000 mg ngosuku, okungukuthi wesikhathi ezine ngokuthatha izidakamizwa ngesikhathi umthamo 250 mg, kabili noma 500 mg. Banikezwe izici ukumuncwa umuthi namaphesenti unciphise amathuba ke uma idliwe nokudla, kutuswa ukuba uthathe iphilisi elilodwa imizuzu engu-30 ngaphambi kokudla.

Ukusebenzisa izidakamizwa e Pediatrics

Izingane umthamo incike yobudala. Izinsana kanye nezinsana enyakeni owodwa avunyelwe ukuletha umthamo zonke izinsuku we-250 mg. ifomu Product - powder for ukumiswa 125 mg / 5 ml. Usebenzisa spoon elandelayo yokulinganisa izikhathi 2 ngosuku. Ingane eneminyaka ephakathi kwengu-iminyaka 6 ubudala avunyelwe ukuthatha ukumiswa okulungiselelwe kusukela "Ospamoks" ukulungiselela ejwayelekile. Umthamo nsuku zonke 375-500 mg: ukumiswa udle ngu yokulinganisa spoon kabili emini.

Kusukela eminyakeni 6 kuya ku-10 ingane endala uyakwazi ngokuzimela ukuthatha imithi tableted "Ospamoks". Umhlahlandlela kusho ukwamukela umthamo zonke izinsuku we-750 mg. Izibhebhe 250 mg kuthathwe kathathu ngosuku ngokuvumelana izincomo udokotela ukuze bayothola ukwelashwa nezikhathi. Uma ngenxa yokuba khona ezinye izifo ezihambisana ne ukugwinya kahle, slurry sisetshenziswa imithamo efanayo. Ngesikhathi esifanayo ngasiphi yobudala kuyadingeka ukuqapha yokwelapha, nokuhlola ukusebenza kwe-ejenti elwa namagciwane kanye ukuhlonza ukusabela ezingezinhle.

Ikakhulukazi imiphumela emibi izidakamizwa

Iqembu imithi elwa namagciwane Nokho, i-penicillin irekhodi ovelele ubuthi ongaphakeme, bathambekele baxabane nomzimba. Ngenxa ukuphepha anobuthi, ukulungiswa "Ospamoks" imfundo evumela ukusetshenziswa isikhathi ezingane ezisanda kubelethwa. Ngaphezu kwalokho, abadala kanye nezinsana izidakamizwa izidakamizwa "amoxicillin" ebangela abanye ukusabela ohlangothini. Ikakhulukazi:

• yokungezwani komzimba njengoba urticaria, conjunctivitis, rhinitis, angioedema, imfiva, eosinophilia, ithatha ezingavamile ukushaqeka anaphylactic;
• Common imiphumela emibi ibandakanya ikhanda, isicanucanu, isiyezi, uhudo, ngokusebezisa isikhathi eside (izinsuku ezingaphezu kwezingu-15 e eziningi izifo);
• crystalluria, nephritis interstitial, ukuthuthukisa ikakhulukazi isicelo kanye metronidazole;
• ngokumelene isizinda yokwelapha antibiotic ingase ukuthuthukisa superinfection phakathi nesigqi kokuba ukumelana ephelele noma isihlobo ukuba "amoxicillin";
• Lapho esetshenziswa njengoba usana angagcina uhudo, imvelaphi fungal.

Izimo

Contraindication is kushintshwe ngaphambili kwenzeka iguliswa aminopenicillin, mononucleosis ezithathelwanayo, isifo sohudo kanye nezifo kwanoma iyiphi ingxenye pheshana emathunjini. Umuthi alisetshenziswa khona isifuba somoya bronchial, izifo ezinzima egazini ngaphandle yezinkinga ezibangelwa amagciwane, lo ukuthola of yokungezwani komzimba ukuze cephalosporins. Lesi sakamuva kuyinto contraindication isihlobo futhi bahlola ngokucophelela, njengoba yokungezwani komzimba engu- ukuba aminopenicillin kwenzeka kuphela 5-20% lwamacala.

Izici isicelo kwabesifazane abakhulelwe kanye lactating

Isici esibalulekile ukusetshenziswa-antibiotic ngesikhathi ukhulelwe ubuthi babo abangahle futhi langempela. Amalungiselelo yenombolo ye penicillins neze akheka futhi excreted ku owaqalwa. Lokhu kusho ukuthi akukho imiphumela anobuthi babangela. Futhi, "Ospamoks" kuyinto ethize maqondana amaseli amagciwane akunamthelela amangqamuzana omuntu.

Uma sicabangela lezi zici, ukusetshenziswa imvume "amoxicillin" ukukhulelwa nganoma yisiphi isigaba ekwelapheni isifo ngokuvumelana izinkomba ngenhla. Okubalulekile, cishe 30% igazi engenayo ku umthamo lisabalalisa ngokusebenzisa placenta futhi mbeni umzimba we-fetus. Ekuhloleni futhi elawulwa izifundo zokwelapha ezihilela abantu engakaze kungase kutholakale imiphumela esinobuthi teratogenic 'Ospamoksa ".

Futhi ayiboniswa ukuthuthukiswa imiphumela teratogenic ezifundweni isilwane ngesikhathi sokukhulelwa. Nokho, ngesikhathi lactation, kubalulekile ukuthi ubeke umkhawulo edonsa antibiotic. "Ospamoks" sihamba kalula ubisi lwebele futhi umntwana esiswini angena egazini. Uma sicabangela ingozi komzimba, isifo sohudo kanye fungal dysbiosis emathunjini izingane kunconywa ukuyeka ibele ngesikhatsi ukwelashwa ngemithi elwa namagciwane.

Class nozakwabo futhi izidakamizwa ejwayelekile

Ngo emakethe yasekhaya ku izidakamizwa yesimanje futhi ephephile "Ospamoks 250" Kukhona analogs egcwele mayelana nedlanzana kokuba intengo ezahlukene. Basuke ekhiqizwa yizinkampani ezimbalwa futhi musa ihluke kakhulu kusukela "Amoxicillin" ezivela kwezinye abakhiqizi. ngqó, impendulo ingu "Ospamoks 1000" yilona ejwayelekile, njengezinye eziningi nezinye lozakwabo yakhe ukubunjwa kanye nefomu ukukhululwa.

On the amalungiselelo ithebhulethi "Ospamoks" intengo ephakeme mayelana 2/3 kuka nozakwabo yasekhaya, esikhishwa JSC "Synthesis". wentengo Pharmacy imayelana 200 ruble. Ukuze okufanayo kahle umbandela oluthandwa iyisici intengo. Uma sicabangela izici Tactical kuleli cala, kuphezulu kunikezwa izidakamizwa eziningi ezifuywayo, okuyinto angathengwa ruble 30 nje (20 nama-PC.).

aminopenicillin evikelwe

analogs Pediatric "Ospamoksa", "Augmentin" futhi "Hikontsil" ngesimo izimpushana ukulungiswa ukumiswa izidakamizwa elinesimo kahle efanayo njengoba analogs Russian kufinyeleleke kalula. Ububanzi isicelo salokhu kwamuva, kuhlanganise yasekhaya, nomkhawulo amagciwane abe nenkani ukuze amoxicillin. Ngakho-ke, ngokuvamile kakhulu esetshenziswa seyivikelekile aminopenicillin clavulanate. Lezi ngezilapha magciwane (bheka ngenhla ukuze uthole amagama) maningi nethonya elinamandla futhi ububanzi spectrum imithi elwa nawo.