Izimpawu ezihlobene ne hemolytic-uremic syndrome ne nokwelashwa kwayo

Ngakho, yini okudingeka ukwazi kuqala kunazo zonke ngenxa hemolytic-uremic syndrome (esifushanisiwe - Hus). Odokotela bathi lokhu kubangwa isifo ngokuyinhloko izimpawu ezintathu: ukwehluleka oyingozi so-renal, anaemia hemolytic, thrombocytopenia. Kufanele kuqashelwe ukuthi isici yokugcina ngokuvamile abonisa ngayo ngokucacile kakhulu. Lesi sifo sitholakale umuntu ikakhulukazi izingane ezincane.

izimbangela

Izinto eziyinhloko ezihlobene hemolytic-uremic syndrome - ukusabela iguliswa imithi, kanye igciwane lohlobo. Kunengqondo ukuthi lesi sifo uqala ukuthuthukisa ngemva sibi zokuphefumula nasesiswini izifo noma seziguli ezithola imithi elwa namagciwane. Ngokuphathelene pathogenesis ka Hus, kulesi sici, kubaluleke kakhulu unamathele khona ukusabela sokuhlasela kwamasosha omzimba. Kwezinye izimo, bangase ukunikeza ngisho kubabangele microangiopathy letindzala.

symptomatology

Yini izimpawu ngokuvamile zibangelwa hemolytic uremic syndrome? Kufanele kuqashelwe ukuthi i-course sifo odokotela evamile ihlukaniswe izinkathi ezintathu. Okokuqala, prodromal, ingahlala ejele usuku olulodwa kuya emasontweni amabili. Okwesibili, okubizwa ngokuthi "isikhathi esibucayi" - kusukela emasontweni amathathu. Bese kufika isikhathi yokuthola (noma ukufa) isiguli.

Ingxenye yokuqala lesi sifo sisonke sifana ubuthi futhi kuhambisana izimpawu ezifana ukuhlanza, ezinzima ubuhlungu esiswini, uhudo kanye iminonjana igazi. Ezinye iziguli kuleli qophelo imakwe Ukudlikizela, ukozela ngisho nokulahlekelwa ukwazi. Ngemva kwesikhathi prodromal ezigulini eziningi kuza yokutakula ebonakalayo. Nge haemolytic uraemic syndrome Ochwepheshe ezihambisana njengoba anaemia haemolytic, thrombocytopenia, kanye izilonda kwezinso. Odokotela bathi isithombe zokwelapha, njengoba umthetho, yayiphawuleka ngokuthambekela polymorphism. Kwezinye iziguli, izimpawu zingase zingaphumi hemolytic esibucayi, abanye - izimpawu acute ukwehluleka kwezinso. Common wonke amacala kubhekwe njengophawu lokuba anaemia hemolytic - buvela phakathi Hus.

Hemolytic-uremic sifo ngo izingane esigabeni sesibili elinesimo pallor elibulalayo kwesikhumba. Ephambi kwezinduna jaundice kungatholakala hyperbilirubinemia. ukuhlolwa Coombs okuqondile 'ngokuvamile omubi, i-hemoglobin kwehlisa, isibalo erythrocyte encishisiwe. Futhi, iziguli kaningi ikhala ngopha.

ukuhlola

Odokotela bavame ukuxilonga Hus, okusekelwe criteria ezintathu eziyinhloko: khona igazi hemolytic, thrombocytopenia purpura futhi uremia. Ngokuvamile, isithombe sokucindezeleka okusikhumbuza Moshkovitsa syndrome (isifo sezinso, amahlule izitsha, nokunye. D.), Nge umehluko kuphela nokuba ukuthi mithandazo ngokuvamile kubonakala izingane ezindala, futhi mikrotrombozov kwenzeka ikakhulukazi inhliziyo futhi isibindi.

Hemolytic uremic syndrome: ukwelashwa

Lokucindezela autoaggression - yilokho iwumgomo oyinhloko ukwelashwa. Njengomthetho, odokotela wathumela wonke amabutho aphume ukuvimbela coagulation intravascular. Awu ukusiza heparin futhi prednisolone. Uma imithi kungasizi, sikhonjiswa hemodialysis.