Isigaba follicular we umjikelezo wokuya esikhathini uwubufakazi

isigaba Follicular - lena yesigaba sokuqala lomjikelezo wesibeletho, esibonakala by ukukhula kanye nokuvuthwa we follicle.

isigaba Follicular noma njengoba ibizwa, i-estrogen, kuthathela ngosuku lokuqala lokuya esikhathini kanye ihlala kuze kube ngomzuzu lapho amaqanda ungazange wavuthwa eyodwa noma dominants eziningana follicle. Ukuphela kwalesi isigaba - ukukhiqizwa kwamaqanda.

ubude bayo zingase zihluke kakhulu. Kaningi kuna ukubambezeleka nyangazonke zenzeka ngenxa nokuvuthwa kancane follicle. Isici esiyinhloko ukuthi kuthinta isikhathi yale nqubo yisikhathi kuthatha ukuba behlise isidumbu sayo sifinyelele ezingeni esiphezulu estrogen.

Ngokusho izinguquko tekusebentisa morphological e ezikhiqiza amaqanda umjikelezo wanyanga zingahlukaniswa izigaba ezilandelayo:

1) Isigaba Follicular;

2) Ovulatory;

3) luteal;

4) Kokuya esikhathini.

Lokho isigaba lomjikelezo, okuholela nge-ovulation ubizwa ngokuthi follicular. Ngokuvamile, kuthatha kuphela engxenyeni yokuqala ka umjikelezo, kodwa kwesinye isikhathi kungathatha isikhathi eside. Isilinganiso umjikelezo isikhathi - kwezinsuku ezingu-28. Noma yimuphi ukuphambuka kusuka kule nombolo kuphela kubangelwa isikhathi isigaba follicular.

isigaba Follicular libhekene ukwanda ezikhulayo zamagama kanye ukukhululwa kwe estradiol futhi inhibin. I lokuhlushwa la ma-hormone inyuka hhayi kuphela e kwegazi, kodwa futhi uketshezi follicular. Somewhere izinsuku 2 ngaphambi kokuya esikhathini kuqala ukuthuthukiswa follicle kusukela yokuphumula yayo noma ifomu primordial.

Ngaso nje leso sikhathi esibelethweni efa umzimba ophuzi, eyasungulwa emuva emjikelezweni odlule. Umphumela yale nqubo - ukwehla elibukhali lokuhlushwa estradiol, progesterone, futhi inhibin (ukuqothulwa kwamahlathi ngezinga elincane).

Ezinsukwini 4-5 kwalesi isigaba dormancy uqhubeke ukuphuma nokuthuthukisa wesibeletho follicle primordial. Follicle-inkanuko i-hormone (FSH) iqala ntombazane cell ayanda, okuyinto umsebenzi kwandisa kakhulu. Lokhu kuphumela eqinisa kumiswa androgens estrogens kuthiwa kwemiqondo amaseli interstitial.

Follicle kwakhiwa okwamanje ngokuvamile akanawo isendlalelo esisodwa lamaseli follicular ezungeze oocyte. Ngaphezu kwalokho, i-cluster elincane uketshezi follicular khona phakathi kwalezi amaseli. Follicle-inkanuko i-hormone iqala ntombazane ukubukeka inombolo enkulu nakakhulu receptor ngoba receptor LH futhi siqu. Futhi kwandisa ukuzwela kwabo luteinizing hormone.

Isigaba follicular libhekene yokuthi umjikelezo 6-7 ngosuku, omunye follicle abasafufusa kuqala ukwanda. Vele yena uzobe kuqhutshekwe athuthukile futhi emva ovulates mayelana umjikelezo 13-15 ngosuku. Ukuze le follicle evelele libhekene mitotic umsebenzi eliphakeme lamaseli follicular, ekuqongeleleni eliphakeme hormone follicle-inkanuko e folllikulyarnoy ketshezi.

follicle Non-evelele abe isilinganiso eliphezulu androgens futhi estrogens, futhi uthi kumaseli follicular kwehle umsebenzi aromatase. Okunjalo-non-evelele follicle Ingahlehlela (atresia). Androgens - esiyinhloko ngokuyenga atresia.

Late futhi phakathi esigabeni follicular we umjikelezo wokuya esikhathini uwubufakazi libhekene i ukwanda ngisho nakakhulu synthesis estradiol futhi inhibin B, okuholela okusithiyayo ukukhiqizwa hormone follicle-inkanuko ngu indlala pituitary khimilili ukukhula follicle entsha. Ukwanda estradiol futhi kuholela ekwandeni ku uketshezi of luteinizing kwama-hormone ukwanda ukuzwela wesibeletho ukuze gonadotropins. Ngaphezu kwalokho, okuqukethwe okusezingeni eliphezulu estrogen obangela ukukhula endometrial. Izinguquko ezinjalo, ngakho abizwa ngokuthi "ukwanda isigaba".