Incazelo kanye Umsebenzisi "Melitora"

Kuleli zwe lanamuhla abantu abaningi bajwayelene kulesi simo, efana ukucindezeleka. Lolu hlobo isifo sokuphazamiseka kwengqondo, esibonakala by isimo sokucindezeleka, ukulahlekelwa ikhono ukujabulela, kanye ukuhlukumeza yokucabanga (ohlangothini negative) kanye motor retardation.

Phakathi ukucindezeleka abantu is kakhulu ziyancipha ukuzethemba, futhi kukhona ukungasathandi emisebenzini evamile nangokuphila sekukonke. Kwezinye izimo, isiguli uqala ngotshwala noma iyiphi imfuyo. Ngaphezu kwalokho, abantu baye eside wahlushwa inkinga yokucindezeleka ngokomzwelo, ukuzibulala. Ngakho-ke uphume esesimweni esinjalo kufanele kube impoqo. Ukuze wenze lokhu, sicela uxhumane udokotela abanolwazi.

Inani elikhulu weenhlahla onguchwepheshe ukukhiqizwa okuthiwa antidepressant. Lokhu izidakamizwa psychotropic ukuthi nethonya eliqondile ezingeni neurotransmitters, kuhlanganise Dopamine kanye le-serotonin. Ngo umuntu odangele mathuluzi ngcono isimo, ukunciphisa ukukhathala, khulula ukucindezeleka, ukuqeda ukukhathazeka, ukungabi nandaba nokucindezeleka okungokomzwelo.

Omunye ethandwa kakhulu izidakamizwa antidepressant kuyinto "Melitor". Yokusetshenziswa, ukubuyekezwa mayelana nomkhiqizo okwelapha izokwethulwa ngezansi.

Incazelo, ifomu ukukhululwa, ukubunjwa, emaphaketheni

I nomuthi "Melitor", imiyalelo for ukusetshenziswa okuyinto linamathele ibhokisi, itholakala ifomu tablet. Banesimiso ukuma side futhi umbala owolintshi njengotshani noma ephuzi. Futhi, izidakamizwa embozwe ikhava ifilimu. Kolunye uhlangothi ithebhulethi kuyinto nomkhiqizi logo ukuphrinta.

Ngo ukudayiswa amaphilisi beze ibhamuza amaphakethe of izingcezu 14.

Noma yini esaluketshezi iqukethe imithi "Melitor"? Iziyalezo yokusetshenziswa uthi isithako yayo iyasebenza, agomelatine izenzo. Futhi e izibhebhe zihlanganisa izakhi ezengeziwe ngesimo stearic acid, monohydrate lactose, povidone, corn isitashi, sodium glycolate (uhlobo A) isitashi, anhydrous Silica colloidal kanye magnesium stearate.

kwemithi

"Melitor" Tablets (yokusebenza imfundo kuchaziwe ngezansi) ungumenzeli antidepressant esithinta isimiso sezinzwa futhi ngempumelelo kuzibonakalisa ngezindlela ezihlukahlukene zokucindezeleka. Ngaphezu kwalokho, lokhu izidakamizwa ngokuvamile iphutha nge de-ukuvumelanisa isigqi lomzimba, ukukhathazeka nokucindezeleka.

I asebenzayo izidakamizwa izidakamizwa kubhekwa melatonergic agonist MT2- futhi MT1-yokwamukela omelene futhi 5-HT2C receptor. Leli thuluzi ayinakho ziyezwana ngoba cholinergic, histamine, dopaminergic, beta- futhi receptor-alpha-adrenergic futhi benzodiazepine, futhi akashintshi degree of kuheleza monoamines. Lesi sidakamizwa ukuvumelanisa isigqi lomzimba, ke normalizes isakhiwo ubuthongo, ezizokhuthaza ukukhiqizwa kwe-melatonin futhi kusiza ngilale.

Uma usebenzisa izidakamizwa ekwelapheni abantu ohlushwa ukucindezeleka ngokomzwelo, kukhona yokwandisa iminyaka slow wave ubuthongo. Kepha REM, awusebenzi ibhekane noma yiluphi ushintsho.

Kufanele kuphawulwe ukuthi leli thuluzi uyakwazi inkanuko ukukhululwa kwe noradrenaline futhi Dopamine e cortex we Lobe ngokuqondile zobuchopho. Kulokhu, agomelatine ayishintshi ezingeni serotonin extracellular.

izakhiwo zomuthi

Yiziphi izinto ezinganembile esivela izidakamizwa "Melitor"? Imiyalelo, ukubuyekezwa bathi e amavolontiya aphilile akazange abe nomthelela omubi inkumbulo, isisindo somzimba, ikhono ukugxilisa ingqondo, umfutho wegazi, kwenhliziyo umsebenzi zocansi. Ngaphezu kwalokho, agomelatine akakubangeli umlutha. Ngemva ukwelashwa ukuhoxiswa engakaze athuthukile.

kinetics

Uyini izakhiwo kinetic we imithi phambi kwethu? Elikushoyo kusenza yokuzenzela? "Melitor" is kahle ugxile kusukela pheshana emathunjini. bioavailability elingaphezu kukahhafu 3%. Kodwa kuncike izici umuntu angase abe nokushintshashintsha abalulekile. Ngokwesibonelo, bubuhle ubulili bioavailability zomuthi ingaphezu kwe ezingabantu. Ngaphezu kwalokho, ukubhema kunciphisa izinga wathi, kanye nokusetshenziswa zokuvimbela inzalo temlomo, kunalokho, kwandisa.

Ubuningi isiqongo isithako esebenzayo egazini waphawula emva kwemizuzu 70-100 emva ekuphathweni ngomlomo. Ukuze ngezinga eliphezulu mayelana antidepressant ukuze plasma amaprotheni (95%).

Umzimba izindlela kwenzeka kwesibindi compounds esingasebenzi. Kuboniswa izidakamizwa izinso (cishe 80%) amahora amabili.

ubufakazi

Kungani sidinga ikhambi "Melitor"? Umhlahlandlela ibika ukuthi izidakamizwa yakhelwe ekwelapheni abantu abane iziqephu sokucindezeleka.

Izimo

Lapho Ngingezame liqoke antidepressant phambi kwethu? Elikushoyo kusenza yokuzenzela? "Melitor" is contraindicated ku:

• hypersensitivity ngakunye izidakamizwa;
• lactase ukuntula;
• umsebenzi isibindi ezinzima;
• malabsorption glucose / galactose;
• e sokuguga;
• azalwa naso galactose ukungabekezelelani;
• ukhulelwe;
• njengoba ingane;
• ibele.

Ngaphezu kwalokho, kusho okunqunywe ngokuqapha in iziguli hypomania noma mania emlandweni, ephula izinso, e umlutha wotshwala (esimweni esinjalo, uma umuntu uthola ukunakekelwa imithi hepatotoxic).

imfundo

"Melitor" senzelwe abaphathi ngomlomo. Tablets zigwinywa lonke ngaphandle ukuchoboza noma ukuhlafuna. Uphuzwe kungakhathaliseki ukusetshenziswa ukudla. With ukuthuthukiswa side effects kusukela pheshana emathunjini kanye imithi lingasetshenziswa lapho udla.

I umthamo wansuku zonke kumele kusetshenziswe kanye ngosuku, ngesikhathi sokulala.

Ubude sokwelashwa umthamo imithi udokotela enquma umuntu ngamunye.

Ngokuvamile omdala linqume ku 25 mg izidakamizwa ngosuku. Lapho waveza umphumela enganele zokwelapha emva 2 amaviki ukwelashwa umthamo luyanda 50 mg ngosuku.

Abantu abathola ukwelashwa okunjalo kufanele kubhekwe umsebenzi sesibindi.

Course isikhathi in iziguli ukucindezeleka akufanele kube ngaphansi kuka-izinyanga eziyisithupha.

side effects

Well uma ibekezelelwe izidakamizwa phambi kwethu? Yini lokhu ekutshela yokuzenzela? "Melitor" kuphela kwezinye izimo, kubangela ukuthuthukiswa amathuba okuba nemiphumela engemihle. Kulokhu, iningi labantu emva 2 amaviki.

Ngakho, uma uthatha ithuluzi kungenzeka ezigulini:

• isicanucanu, gastralgia, sezinyawo kahle, kukhuphuke isibindi transaminase kanye ne-hepatitis;
• isiyezi, migraine, ikhanda, angaboni kahle, sihlale siphapheme kahle futhi imodi yokulala, paresthesia, ecabanga ukuzibulala ukukhathazeka causeless;
• ukuqubuka kwesikhumba, isifuba, ukulunywa, ukuqubuka erythematous futhi eczema;
• myalgia, asthenia, iqolo.

izidakamizwa ukweqisa izidakamizwa

Yiziphi izimpawu zenzeka lapho ukweqisa izidakamizwa amaphilisi "Melitor"? Manual ithi okwamanje kwesikhathi imibiko enjalo ezigulini abikwe. Ngemva kokuthola lezi izidakamizwa ebulilini kuboniswe lavage esiswini kanye ehnterosorbentov eyanele. Futhi ukwelashwa lingaze.

izidakamizwa ekuhlanganyeleni

I kinetics zomuthi olucutshungulwayo ingahluka uma kuhlangene nezidakamizwa akheka ngu cytochrome enzymatic CYP 2C9 / 19, futhi P450 1A2. Ikakhulukazi, it is hhayi Kunconywa ukuba ukwabela izidakamizwa nge "ciprofloxacin" futhi "fluvoxamine".

Kepha "propranolol", "enoxacin", "Grepafloksatsina", kufanele siyisebenzise ngokuqapha okukhulu kulabo kakade yokwelapha "Melitorom".

Nutrition nokukhulelwa

Ingabe inkathi sokukhulelwa ukuthatha izidakamizwa "Melitor"? Umhlahlandlela ibika ukuthi leli thuluzi angabelwa kwabesifazane abakhulelwe, kodwa kuphela ngenxa yezizathu zempilo. Animal ucwaningo lwabonisa ukuthi agomelatine akuphazamisi omubi ukuthuthukiswa umbungu. Nakuba idatha ukuphepha leli thuluzi kwabesifazane abakhulelwe akwanele.

Uma izidakamizwa liyadingeka phakathi lactation, kufanele uxhumane nodokotela wakho bese unquma ekunqanyulweni kwe ibele.

izincomo Specific ukuthola imithi

Yini odinga ukukwazi ngaphambi kokuthatha imithi "Melitor" (25 mg)? Imiyalelo, ukubuyekezwa ukubika ukuthi leli thuluzi akunconyelwe ezigulini esezikhulile.

With ukuthuthukiswa izimpawu ukwenama, ukwelashwa kufanele uphazamiseka.

Kwezinye izimo, ngcono ngemuva kokuthatha amaphilisi ingekho Emasontweni ambalwa okuqala. Ngakho-ke, isimo lesiguli kudinga ukuqapha njalo. Okwakuhlalwa kuzo lapho kusaqalwa yentuthuko yokutakula imicabango yokuzibulala wande.

Zonke iziguli ethola "Melitor", qiniseka ukuthi ukuqapha umsebenzi kwesibindi. Lapho amazinga aphakeme transaminases e ukuhlolwa kwegazi kufanele liphindwe ezinsukwini ezimbili. Ngokwandisa indices izikhathi 3 yokwelapha imisiwe.

Ukwelashwa kubhekwe idingekile ukuze izidakamizwa ngokuqapha uma isiguli engcupheni ka isibindi ukulimala, kuhlanganise ukukhuluphala, non-utshwala okunamafutha isifo, kanye ne abalulekile utshwala, noma kanyekanye abathola izimali nemiphumela hepatotoxic.

Analogs kanye nezindleko

Inani antidepressant "Melitor" kuyinto ruble 850. Uma kudingeka, indlela ungayithola enye by izidakamizwa ezifana "Lotosonik", "Azafen", "Neurol," "Adepress", "Tsetol", "Sevpram", "Zaloks", "Trittiko" futhi t. D.

nobufakazi

Manje uyazi izakhiwo antidepressant ngokuthi "Melitor". Yokusetshenziswa lomutsi iye echazwe ngenhla.

Iziguli eziningi zithi leli thuluzi ngempumelelo kuzibonakalisa ngaba nokucindezeleka okukhulu. It iqeda ukucindezeleka, kunciphisa ukucobeka bese ibuyisela nogqozi lokuphila. Nokho, kufanele kuphawulwe ukuthi linqume lokhu izidakamizwa kufanele kuphela kube abanolwazi lochwepheshe. Ukuthi uzokwazi ukucacisa sokunamathela esilinganisweni esiphephile imithi kanye nesikhathi sokwelashwa.

Futhi, uquketheni lowo abathengi ithuluzi zihlanganisa okungenzeka ongaphakeme yemiphumela emibi, contraindications esincane lula lisetshenziswa (ithebhulethi ukuba kuthathwe kanye ngosuku).

Ngokuqondene nemiphumela ethile engathandeki, kuphela izindleko aphezulu izidakamizwa abaziphatha ngayo.