"Fortum kuyinto": yokusetshenziswa. Inani, indawo, izibuyekezo, analogue zomuthi

Kungani sidinga ikhambi "Fortum"? Imiyalelo ukusetshenziswa kwezimali, ukubunjwa yayo, emabhokisini futhi ifomu ukukhululwa izokwethulwa kulesi sihloko. Futhi kuyo, uzofunda ukuthi lena izidakamizwa lapho anakho side effects kanye Izimo, lapho babe analogue zomuthi, nokuthi kubiza kangakanani.

Ukwakheka kanye nefomu emaphaketheni

ungakwazi ukuthenga idivayisi wezokwelapha "Fortum" ngayiphi indlela? Medicine, izincwadi esizifundayo, okuthengiswa ifomu powder. Isetshenziselwa ukulungiswa isixazululo umjovo. 1 ibhodlela iqukethe izidakamizwa oyibamba isici ezifana ceftazidime (ngesimo pentahydrate). Ngokuphathelene izingxenye ezincane, bese bahlanganisa anhydrous sodium carbonate ne-carbon dioxide. Ngo isixha amakhadibhodi 1 isitsha.

Izimfanelo kwemithi zomuthi

Uyini izidakamizwa "Fortum"? Iziyalezo yokusetshenziswa uthi kulesi sizukulwane cephalosporin-antibiotic lwesithathu. It kunomphumela amagciwane. Eba yomzimba, izidakamizwa kunikeza ukuhlanganiswa kwezici odongeni cell microorganism.

Umuthi has a spectrum ezibanzi yesenzo (e elwa namagciwane ethile). Uwoyela ubulala amagciwane kwamagciwane amelana gentamicin nezinye imithi elwa namagciwane bohlanga aminoglycoside. Nokho, siphawula ukuthi umuthi amelana kakhulu beta-lactamases.

Lezi zifundo yembula ukuthi asebenzayo izidakamizwa izidakamizwa esebenzayo ngokumelene amasethi igremu-HIV, Gram-negative futhi anaerobic gciwane, okuhlanganisa ukuhlanza nesigqi amelana ampicillin.

Kufanele kuphawulwe ukuthi ceftazidime ayisebenzi ngokumelene staphylococci methicillin nemithi.

Pharmacokinetics zomuthi

izidakamizwa "Fortum" How fast kanjani? Ama-antibiotic ngemva esicutshini noma ekuphathweni emthanjeni at esenikwe 1 mg 500 g futhi ngokushesha kakhulu zitholiwe oketshezini olungenambala lwegazi. Ngalesi lokuhlushwa uyilingu zokwelapha egcinwe amahora mayelana 8-13. Ngokuphathelene ukuzihlanganisa namanye amaprotheni, kumayelana 10%.

I lokuhlala lomcebo asebenzayo okweqa MIC iningi ingxenye amagciwane ezivamile pathogenic kungafinyelelwa in the Bile, ithambo izicubu, isikhwehlela, izicubu inhliziyo, lwamalunga, pleural, futhi peritoneal uketshezi intraocular.

Ngizothanda futhi ukubalula yokuthi ceftazidime lingena ngempela kalula ngokusebenzisa isithiyo esinomhlapho futhi excreted nge ubisi lwebele. In the ukungabikho ukuvuvukala e nolwelwesi meningeal isici asebenzayo nomuthi ngokwanele kahle zingene Bbb. Kulokhu kusho lokuhlushwa i-cerebrospinal fluid sincane kakhulu.

Kubhekwe izidakamizwa akuyona akheka emzimbeni womuntu. Ingxenye-ukuphila nomuthi ngema-awa lange-2. Ceftazidime ivela umchamo ngefomu zinjalo.

Kufanele kuqashelwe ukuthi izinga excretion we ketshezi esebenzayo abahlukene kwehliswa umsebenzi kwezinso.

Izinkomba ukusetshenziswa

Kwezinye izimo, linqume imithi "Fortum"? Yokusetshenziswa zihlanganisa uhlu olandelayo ukufundwa:

• izifo kubantu ene-cystic fibrosis, kanye zokuphefumula ipheshana izifo;
• ngamagciwane okunzima, kuhlanganise nosocomial (peritonitis, septicemia, meningitis, bacteremia, Burns abangenwe izifo kubantu abanegciwane amasosha omzimba kwehlisa);
• izifo ekhaleni, emphinjeni kanye izindlebe;
• elithambile izicubu izifo, futhi isikhumba;
• pheshana urinary nezifo;
• izifo amalunga namathambo;
• Kwesisu ipheshana ukutheleleka, ipheshana biliary futhi ngaphakathi komgodi ongaphakathi kwamathumbu;
• izifo ezihlobene isebenzisa umshini wezinso.

Futhi, izidakamizwa ngenkuthalo esetshenziswa nokuvimbela yezinkinga ezithathelwanayo emva kokuhlinzwa wendlala.

Izimo ukusetshenziswa

Kwezinye izimo, imithi akufanele okunqunyiwe "Fortum"? Yokusetshenziswa iqukethe uhlu elandelayo Izimo:

• anda nozwela isiguli ceftazidime nezinye izakhi zomuthi;
• izingane osanda kuzalwa;
• anda ukuzwela nesineke penicillin futhi cephalosporin antibiotic.

Phawula futhi ukuthi lokhu izidakamizwa ezinqunyiwe ngokucophelela okukhulu kubantu nge isifo sezinso, izifo emathunjini, ngesikhathi ekhulelwe, ngesikhathi lactation, lihambisana aminoglycosides futhi isisu.

ekusetshenzisweni umkhiqizo okwelapha

Indlela yokufaka isicelo kahle imithi "Fortum"? Imijovo iqondiswa iziguli umuntu ngamunye. Isikali kangakanani kuncike ekutheni ngobucayi isifo, kanye kwasendaweni, kuvelana izidakamizwa, uhlobo lwegciwane, ubudala lesiguli kanye umsebenzi kwezinso.

Umuthi iqondiswa ngemithambo yegazi noma intramuscularly ezijulile (engxenyeni lateral senyonga noma elingenhla quadrant elingaphandle maximus gluteus). Futhi kungenzeka ikhambi ukumnika busuka uhlelo tube.

Umthamo wansuku zonke zomuthi (esiphezulu) imayelana 6 g abadala ukhethe 1-6 g ngelanga ngemithambo yegazi noma intramuscularly. Kaningi ekuphathweni - 2-3 izikhathi ngosuku.

Ngokuvamile wacabangela nomuthi iqondiswa 2 g ngezikhawu amahora 12 noma 1 g njalo ngemva kwamahora 8.

Uma isiguli isifo ezinzima nokuvikeleka encishisiwe, futhi ine neutropenia ke kunikezelwe 2 g izidakamizwa njalo ngemva kwamahora 8 noma ezingu-12. Kungase nazo zingabizwa 3 g izidakamizwa njalo ngemva kwamahora angu-12.

Njenganoma izifo zamaphaphu ukugeleza kanye pheshana urinary nezifo, ukusetshenziswa kwezidakamizwa "Fortum"? Analogs kusho uqobo kanye izidakamizwa iqondiswa emqulwini ka 1 ml noma 500 g njalo ngemva kwamahora nambili.

Ukuze ukwelashwa yezinkinga ezithathelwanayo nge kuka ezifana cystic fibrosis, umuthi isetshenziswa inani 100-150 mg ngayinye kg ngosuku (ihlukaniswe izikhathi 3).

Phakathi ukuhlinzwa phezu nomuthi wendlala indlala isetshenziswa umthamo 1 g at lokungeniswa ngokusungula indlela yokubulala izinzwa, umthamo yesibili iqondiswa ngesikhathi ekususweni ipayipi.

ezigulini esezikhulile (ikakhulukazi abantu abaneminyaka engama-80), umuthi is ebekiwe lemali ezingekho ngaphezu 3 g ngosuku.

Izingane ezindala kuka-2 izinyanga kwezidakamizwa iqondiswa ngezilinganiso ka 30-100 mg ngayinye kg ngosuku. Uma lokhu kokukhulisa kuyinto ukuphatha izikhathi 2-3.

Abantwana abane-meningitis,-cystic fibrosis, noma immunocompromised eyabelwe 150 mg ngayinye kg ngosuku. Umthamo obuyisilinganiselo 6 g (hlukanisa imali yazo ngo izikhathi 3).

Izinsana nezingane osanda kuzalwa ezingaphansi kweminyaka engu-ngemva kwezinyanga ezimbili, izidakamizwa ezinqunyiwe kuphela ezimweni ngazinye. Ngaphezu kwalokho, umthamo yayo kufanele kube 25-60 mg ngayinye kg ngosuku (ihlukaniswe ngesigamu).

Abantu abanegciwane le-ukwehluleka kwezinso kudinga umthamo esincishisiwe ejenti, njengoba ceftazidime ngokukhishwa ngu izinso ngefomu zinjalo. Umthamo lokuqala kulezi ziguli 1 g Ngokuphathelene ngevolumu ukwesekwa, it is abakhethiwe ngamunye (kuncike glomerular filtration isilinganiso).

ukweqisa izidakamizwa

Kungakhathaliseki imithi ezibizayo noma ezishibhile oyisebenzisa kakhulu ukuze yelaphe izifo. Kunoma ikuphi, kufanele kusetshenziswe kuphela kadokotela.

Uma ubika ngemithi elwa namagciwane ukuthi isetshenziswa esengeziwe, khona-ke isengozini ukweqisa izidakamizwa zimpawu ezilandelayo: iziyaluyalu esithinta izinzwa, kuhlanganise sokuwa ikhoma futhi encephalopathy. Ekwelapheni izifo ezifana odokotela batusa yokwelapha lingaze futhi basekelane.

imiphumela emibi izidakamizwa

izidakamizwa eshibhile, kanye ezibizayo eziphathelene antibiotic, ube nenamba kahle esikhulu amathuba okuba nemiphumela engemihle. Cabanga uhlu kubo.

• Ukugaya: isicanucanu, candidiasis we ngalo ingaphakathi ngomlomo kanye pharynx, jaundice, uhudo, ubuhlungu besisu, ukuhlanza kanye nokwenyuka lezivakashi e umsebenzi GGT, LDH, AST, ALT, futhi ALP. Ngaphezu kwalokho, njengoba namanye cephalosporins, izidakamizwa esebenzayo kungabangela nesifo pseudomembranous.
• Central ne-peripheral nervous system: paresthesia, ikhanda, isiyezi, dysgeusia, iziyaluyalu esithinta izinzwa, kuhlanganise nokundindizela, Ukudlikizela, myoclonus, encephalopathy futhi equlekile.
• uhlelo hemopoietic: leukopenia, eosinophilia, lymphocytosis, neutropenia, thrombocytopenia, agranulocytosis, anaemia hemolytic, futhi thrombocytosis.
• System urinary: ukuphazamiseka izinso, ukwanda lezivakashi e urea kanye urea nitrogen ne creatinine egazini.
• Komzimba: ukwehlisa umfutho wegazi, ukuqubuka maculo-papular, imfiva, urticaria, bronchospasm, pruritus, angioedema, erythema multiforme, kuhlanganise Stevens-Johnson syndrome, epidermal necrolysis anobuthi (ie Lyell Syndrome).
• ukusabela Local Esibi: thrombosis noma phlebitis (ngomjovo), uphawu ngesikhathi ujove esicutshini, ubuhlungu nokusha.
• Okunye: Direct Coombs 'test (okungamanga) kanye Candida lezinkinobho.

Ukusebenzisana neminye imithi

Ingabe kukhona uhlu imithi ngazo izidakamizwa "Fortum" kungenzeka noma, kunalokho, ingasetshenziswa yini? Kumele kuqashelwe ukuthi ayikho ohlwini ethize. Nokho, ngaphambi kokusebenzisa leli thuluzi, kuphoqelekile ukuba ufunde imiyalelo, kodwa kunalokho ngokusebenzisa "ekuxhumaneni izidakamizwa". Kusukela ke uzothola ukuthi ukusetshenziswa ngesikhathi esisodwa ceftazidime e imithamo ephezulu kanye nemithi nephrotoxic angase abe nemiphumela engemihle izinso.

Isisu, vancomycin, aminoglycosides futhi clindamycin kakhulu ziyancipha imvume we ketshezi esebenzayo izidakamizwa, okuholela kwengozi imiphumela nephrotoxic.

imithi elwa namagciwane Bacteriostatic, kuhlanganise izidakamizwa "Chloramphenicol" ukunciphisa umphumela we-beta-lactam antibiotic.

Nomuthi "Fortum" iyahambisana cishe zonke izixazululo ekuphathweni emthanjeni. Nakuba kunjalo, kufanele kuphawulwe ukuthi ceftazidime akuyona esitebeleni isixazululo sodium Bicarbonate. Kule ndaba, ketshezi akuvunyelwe kuphela.

Izikhombisi-ndlela ukusetshenziswa imithi

Okufanele ukwazi ngaphambi kokusebenzisa "Fortum" izidakamizwa? Umthelela kwamaphilisi kungahle kube yingozi enhlalakahleni iziguli. Uma iziguli uvele ukusabela iguliswa, umuthi kufanele uyekwa.

ukusetshenziswa isikhathi eside lokhu nomuthi kungaba nomthelela ukukhula anda-bacterium sokushintsha. Kulokhu, singadinga ukuqedwa yokwelapha.

Izidakamizwa "Fortum": nozakwabo kanye nezindleko

Ngokuthi izidakamizwa ezishibhile kubhekwa nzima impela. Ngakho imithi kangakanani "Fortum"? intengo yayo ingase ibe khona ehlukile futhi ancike umthamo imithi. Ebhodleleni-500 ml Ungakwazi ukuthenga 196 ruble Russian futhi 1 g futhi 3 g - 452 kanye 626 ruble ngokulandelana.

Cabanga uhlu izidakamizwa kabani isinyathelo kufana izidakamizwa "Fortum":

• "Vitsef";
• "Bestum";
• "Kefadim";
• "Kefadim";
• "Orzid";
• "Lorazidim";
• "Tizim";
• "Fortazim";
• "Tazitsef";
• "Ceftazidime";
• "Tsefzid";
• "Tseftidin".

Uphenyo imithi

Yini iziguli ekushoyo izidakamizwa "Fortum"? Intengo wabo banelisekile nje impela. Ngaphezu kwalokho, iziguli eziningi kakhulu isimo ukuthi kubhekwe lo muthi siyasebenza kakhulu. Nakuba kukhona isigaba iziguli lowo asifanele ngenxa inani elikhulu amathuba okuba nemiphumela engemihle.