Ejenti Antifungal. 'Clotrimazole' wamafutha

Clotrimazole - wamafutha kokuba umbala omhlophe, ukuthungwa bushelelezi futhi kancane isici iphunga.

Ekwakhiweni nezinsizasenzo yilezi: polyoxyethylene-400, propylene glycol, Proxanol-268, OC-20 ukulungiselela, utshwala tsetilstearinovy. Isenzo we ketshezi kuyinto Clotrimazole.

Maze we izidakamizwa antifungal ukusetshenziswa wendawo. Lo mshini wezenzo zomuthi kusekelwe ekunciphiseni izinga synthesis ergosterol, esidingeka ekwakhiweni fungal cell ulwelwesi. Inqubo braking kuphazamisa permeability yayo kanye lysis okwalandela kwamaseli.

Yokugcoba clotrimazole based ibe nomthelela ekubeni permeability ka liposome phospholipid ulwelwesi, vacuolization cytoplasmic, nokuncipha inani ribosomes. Ngenxa yethonya lezingane ketshezi esebenzayo peroxidase okusithiyayo umsebenzi. Lokhu, sekusilethela ekuqongeleleni kumaseli fungal i-hydrogen peroxide, ngekubamba lichaza ukubhujiswa kwalo.

wamafutha Clotrimazole has anhlobonhlobo imiphumela. Imithi siyasebenza ngokumelene dermatophytes, nembiliso. Ngaphezu kwalokho, kuba nethonya elwa namagciwane okuhloswe ngaso streptococci futhi staphylococci.

Ukuze izidakamizwa libhekene okusezingeni eliphezulu Ukungena ikhono. Ukuze ukusetshenziswa ongaphandle emakamu epidermis izidakamizwa kunakunoma emafutheni ongama bese dermis. wamafutha Clotrimazole ku kwegazi is cishe hhayi ugxile. Ngenxa yalokho, izidakamizwa ukweqisa izidakamizwa akunakwenzeka.

wamafutha Clotrimazole. isicelo

Umuthi kuboniswa ezifweni ezibangelwa dermatomitsetami, isikhunta, Blastomyces isikhumba mycosis, kanye yesibili ukutheleleka dermatomycosis (nail mycosis, izinyawo nabanye).

Umuthi sisetshenziswa izikhathi ezimbili noma ezintathu emini endaweni ethintekile wagcoba. Isikhathi izinyathelo zokwelapha kuxhomeke Yiqiniso nobukhali isifo, kwasendaweni izilonda sokugembula, kanye ukuphumelela ukwelashwa. Ngokuvamile, isikhathi inkambo amasonto amane noma ngaphezulu. Ekwelapheni ohlasela ukuze kuvinjelwe Ukuphinda yokwelapha isifo baqhubeka amaviki amathathu emva ukuqedwa izimpawu. Ngaphambi ukusetshenziswa ukulungiswa ngezinyawo zabo kufanele wageza ngensipho namanzi, ikakhulukazi isikhala interdigital, yomiswa. Izindawo ukuthi kuzosetshenziswa lokulungisela kumelwe ahlanzeke futhi abe wawusomile.

Lapho isicelo kuqala ezimweni ezingajwayelekile ezikhonjwe ukusabela wendawo, ebonakaliswa ububomvu, evutha ukuzwa, ukulunywa. Njengomthetho, lezi zimpawu zinyamalale ngesikhathi ukusetshenziswa okwalandela zomuthi.

Izimo ukusetshenziswa ejenti is anda kuvelana ejenti asebenzayo (clotrimazole) noma ezinye izingxenye ze-izidakamizwa.

A ukwehla zomuthi ngesikhathi kufakwa nabanye ejenti antifungal. Isenzo clotrimazole kungehlisa ukusetshenziswa dexamethasone ebulilini.

Ngokucophelela okukhulu kumele kusetshenziswe indlela abesifazane ngenkathi besancelisa kokubeletha. Kufanele kuqashelwe ukuthi izidakamizwa inomphumela omubi phezu impilo yengane kanye nonina. Zibheke ekusebenziseni izidakamizwa Kulezi zimo ixazululwe ngokuqinile ngamunye emva kokubonisana yezokwelapha.

Musa ukusebenzisa izidakamizwa endaweni periocular.

Uma isicelo alikukhuthazi izidakamizwa ukunyamalala izimpawu amasonto amane, kubalulekile ukuqinisekisa (qinisa) uphethwe.

kumelwe uyeke ukwelashwa bese ukhetha ukuphathwa ngesikhathi ukuthuthukiswa ukucasuka noma ukuzwela anda endaweni ngayo.