Calprotectin e sezinyawo - kuyini? Izizathu ukwanda

Calprotectin e sezinyawo - kuyini? Lena iprotheni ukhululeka amhlophe egazi amaseli (macrophage kanye neutrophil) lapho ocushiwe noma ukufa. It ukhonza njengelungu umaka ezithile izinqubo ukuvuvukala emathunjini. Inani quantitative yalesi sifundo ithunzi elehlayo nesibalo egazi amhlophe ukuthi kukhona emathunjini.

Calprotectin e sezinyawo - kuyini?

Le into uyakwazi akhululwe kuphela isebenze egazi amhlophe (neutrophil) noma eyingcuba. Eqinisweni, yiyo kanye amaprotheni neutrophil noma iprotheni lihlotshaniswa calcium. Calprotectin endleni - ke, futhi ngaphansi kwaziphi izimo lapho ebonakala esiswini?

In izifo wamathumbu ukuvuvukala inani leukocyte therein kwandisa. Leukocyte, okungukuthi neutrophil nama uhlushwa ukutheleleka, okwaphumela lidayizi. Lapho befa kwenzeka amaprotheni Ukukhululwa - calprotectin, futhi lokhu kuholela ekuphelelweni lokuhlushwa yayo anda indle.

Ukunqunywa okuqukethwe ambalwa of calprotectin endleni - kuyinto indlela elula non-koda we ekuxilongweni ukuvuvukala wamathumbu isifo (IBD). Lokhu uphethwe ivumela udokotela ukuhlukanisa IBD kusukela engaphathekile wamathumbu syndrome for okungekho ukuvuvukala eyinqaba we ulwelwesi lwamafinyila yaleli pheshana emathunjini (Git).

Lapho kumiswa?

Lolu cwaningo inikezwa uma isiguli izikhalazo ezilandelayo:

• izigqiki Irregular izimbici.
• izigqiki Okuxekethile ngegazi.
• Ubuhlungu besisu futhi ukuthandwa okwandayo kwale nezinga lokushisa komzimba.
• ukujuluka ngokweqile.
• Ngokuzumayo kwesisindo.
• ubuthakathaka Jikelele kanye ukukhathala ngomzamo omncane ngokomzimba.
• Uma ukwephula emathunjini motility.
• Ukucanuzela kwenhliziyo nokuhlanza.
• Uma ukuqunjelwa.
• Ezimweni lapho khona i-pathologies nesineke endaweni perinatal, ezifana abscesses noma fistulas.
• Ngo izingane ukubambezeleka zentuthuko.

Calprotectin endleni: evamile

Amanani lokhu ipharamitha endleni yabantu abanaleli ngokuvamile bakha kusuka 0 kuya ku-10 mg / ml. Uma ezingeni sezinyawo calprotectin luphakathi leli banga, kusho ukuthi isiguli akanayo IBD. mucosa emathunjini akuyona abavusa. Futhi uma isiguli uyaqhubeka esekhala izinkinga emathunjini kanye nesifo sohudo, kungase kusho ukuthi ikhona wamathumbu engaphathekile syndrome. izifundo engeziwe kudingeka ukucacisa uphethwe.

Okuchaza amazinga calprotectin kukhuphuke

Uma calprotectin endleni landa, izimbangela kungenziwa exhunywe hhayi kuphela IBD, kodwa futhi ezifweni amagciwane yokusetshenziswa pheshana emathunjini, njenge-Salmonella, Campylobacter. yokusabela anjalo angase ukutholakala Rotavirus, norovirus noma izifo adenoviral. Ngaphezu kwalokho, kungase kube calprotectin endleni anda ukusabela iguliswa ubisi noma yesifo celiac wenkomo (ukungabekezelelani ukuba gluten eziqukethwe wokudla amasiko) kanye nokuba khona izilonda, diverticula emathunjini noma cystic fibrosis (isifo ngofuzo elihlobene ne izilonda endocrine nezindlala uketshezi zangaphandle).

Kunoma yikuphi kwenziwe ucwaningo?

Cabanga lapho cwaningo babelwe ivumela ukuhlonza calprotectin endleni. Ukuthi kuyini, siye kakade eyakuthola.

Kunesidingo socwaningo olufanayo ezigulini babelwe:

1. Ngenxa luhlolo tekuvimbela Luhlolo prophylactic.
2. Ngoba noma yisiphi IBD okusolwayo.
3. ukopha Lapho emathunjini.
4. Uma izikhalazo ngesineke ubuhlungu besisu futhi isithombe emtholampilo.
5. Ukuze ukuxilongwa umehluko engaphathekile wamathumbu syndrome.

Yini okumelwe uyenze?

Uma sekuvela ukuthi calprotectin endleni yanda, izizathu ukusabela ngaleyo ndlela kufanele esabekwa udokotela. Self-angahlala ngabe yikuphi hhayi kunomvuzo, ngoba kungaba ngempela isifo esiyingozi kakhulu. Udokotela angakwazi ukuxilonga ngokunembile, futhi izifundo ezengeziwe ngezinye izikhathi kungadingeka:

• Coprogram.
• Ukusabela Gregersen, noma fecal igazi nokulumba. Ukuhlaziya okunjalo kudinga ukuqeqeshwa okukhethekile. Kwaphela izinsuku ezintathu kungavumi, isiguli akufanele badle inyama kanye nenhlanzi izitsha, kanye nemikhiqizo equkethe ukubunjwa yayo yensimbi (isibindi, amaqanda, black currant, ushokoledi).
• amaprotheni C-esisheshayo indlela ebucayi kakhulu okuvumela ukucacisa yi ambalwa.
• Isici samathambo.
• Cea (antigen carcinoembryonic).
• Esithi asifane nesika ANA (amasosha antigen senuzi).
• igazi Ubude nge saziso nokubala leukocyte ifomula.

ukwelashwa

Ngakho, lo dokotela wabeka i ukusazi ngokunembile isifo esikuphethe, lapho kukhona izimpawu ukuvuvukala mucosa emathunjini, futhi ngaleyo ndlela anda calprotectin endleni. Ukwelashwa kuzoncika izizathu oholele lokhu ukuvuvukala.

Uma imbangela isifo esithathelwanayo, ezifana salmonella, ukuthi badinga ukwelashwa, okuyinto okudiliza lwegciwane (Salmonella). Futhi udinga ukuthatha sorbents, njengokuthi "Liferan", "amalahle elimhlophe", "Enterodez", "Smecta", njll Ngaphezu kwalokho, amalungiselelo adingekayo ukuze ukubuyiselwa amanzi-usawoti ibhalansi :. "Oral", "Regidron", njll Lapho ukukhanya. uhlobo salmonellosis ngokuvamile imithi ngokweqile zifana nokuthela hhayi oqokwe ngoba lokhu ejenti egomekile kubo.

Lapho isimo viral lesi sifo (adenovirus noma Rotavirus et al.) Kudingeka antivirals. Lokhu kungaba "Arbidol" "Gordoks" "Virazole" et al. Osetshenziswayo immunostimulating nezidakamizwa immunomodulating "TSikloferon" "Anaferon", "Interferon".

Ngokuvamile for ekwelapheni izifo emathunjini antibiotic. Ngokwesibonelo, okunqunyiwe "Ftalazol" nezingane asetshenziswa ngangokunokwenzeka-ejenti ephephile elwa namagciwane nge spectrum ezibanzi isenzo "cefixime".

A nomphumela omuhle kunikezwa enzyme amalungiselelo "enzistal", "zemikhosi".

Kodwa ukwelashwa kufanele aqoke udokotela kuncike izici ngamunye isiguli kanye isimo sakhe.