Assays sama-hormone egilo - umsizi lokuqala ekwelapheni

Kulezi zinsuku izifo ezihlukahlukene futhi isifo esiyingozi indlala yegilo kukhona lalivamile. Ikakhulukazi, kumayelana engxenyeni fair wesintu, njengoba ngokusho izibalo zokugula kwalo ikakhulukazi ebonwe nabesifazane. Futhi kubalulekile ukunquma iyasiza futhi izinguquko hormone ukusebenzisa ku odokotela ukuthola imithi ukuthi zihlolelwe ama-hormone. Kodwa, bambalwa abantu wacabanga mayelana nencazelo izinombolo kanye izibalo, okuyinto okulungiselelwe le nqubo. Zama ukuqonda.

Kuthiwa ama-hormone - a izinto kakhulu asebenzayo ezikhiqiza nezindlala endocrine, ikakhulukazi le ndlala yegilo. Ngu ukuhlaziya ku-hormone egilo zihlanganisa T3 ne-T4 izinkomba ezinjalo, kokubili jikelele kanye khulula.

Kuthiwa ama-hormone i-T4 (thyroxine) kanye T3 (triiodothyronine) abalelwa ku- hormone egilo engeziwe, okuyizinto mahhala futhi lesibopho serum.

Isimo amaprotheni-bound cishe zonke hormone, ngaphandle cishe amaphesenti. Kuleli zinga, awayona asebenzayo, okusho - ayikwazi kunethonya nomphumela walo begazi. Kuye ezahlukahlukene yangaphandle ezihlobene ne-hormone okuthiwa lokuhlushwa kungase kwehluke ngezinye izikhathi.

Ngakho ukunciphisa esibophezelayo hormone barbiturates, Anabolic steroid, salicylates, androgens, glucocorticoids futhi furosemide. Ukuncipha kwama-hormone ahlobene ebonwe isifo sezinso nezifo generalized.

Kodwa ngesikhathi sokukhulelwa, ngesikhathi ezisanda kubelethwa esibophezelayo, kunalokho, anda. I lokuhlushwa i-hormone amaprotheni-bound ingahluka uma sisebenzisa ohlangothini ezinkulu estrogen futhi umuthi ngomlomo, ukuhlaselwa amagciwane, kanye ne-hepatitis okungamahlalakhona, isifo sokuqina kwesibindi kanye negciwane lesandulela ngculaza, porphyria kanti ezinye izifo zofuzo. Futhi njengoba lesi sibalo kaningi siyahlukahluka noma isiqondiso ngaphansi kwethonya izici eziningi, engahlangene zonke izinhlobo zezifo kanye nezinguquko egilo, uye waqala kakade ukusebenzisa kancane.

Manje, uma ukuhlolwa nesineke sama-hormone egilo abadlula Kunconywa ngudokotela wakho, kunikezelwe kuphela T3 khulula ne-T4. Kuyinto hormone atholakala igazi esimweni khulula, ezimele izici zangaphandle, iveze isithombe wangempela isimo kanye nokusebenza indlala yegilo. Isibalo sawo kufanele kube into efanayo njalo, ngakho inani okuholela utshela udokotela wakho mayelana nokuthuthukiswa sifo.

Kuthiwa ama-hormone yiwona izici eziyinhloko wenzalo womuntu. Lapho ukungasebenzi okungenani eyodwa ingxenye lonke uhlelo amaqanda ngxenye-pituitary-ushintsho emsebenzini futhi uhlelo zokuzala, yingakho encishisiwe okuzala. Kuphela ukuze kuhlolwe isimo abesifazane hormone ukuya udokotela ekunika lihlaziya hormone yokukhulelwa.

Ukuphumelela kule ndlala ikhombisa ingxenyenamba mahhala T3 ne-hormone okuthiwa i-hormone i-T4 - umumo ekushintsheni, kuphenduke -hormone okuthiwa i-T3 lapho kudingeka. Ngokuyinhloko, lena 30% i-T4. Njengoba ukuhlolwa-hormone, ngesilinganiso serum simi ngale ndlela: 0.03% - kuyinto T4 khulula futhi 0.3% - T3 khulula.

T3 ne-hormone okuthiwa kathathu e wesenzo begazi asebenzayo kuka-T4, kodwa isigamu-nokuphila salo iri asi-6, kanti, njengoba i-T4 - ngesonto. Mahhala T3 ne-hormone okuthiwa izinguquko njalo ngokwanele, ngisho usuku olulodwa, iyehla iyenyuka yayo ungaxhomeki kuphela ubudala bomuntu, kodwa izifo ezingathi sína. Ngakho-ke aluleka ihlaziya ku-hormone egilo ukudlula ezimweni eziningi kuphela kutholakale izinga T4 khulula.

Ngo inqubo yokwelapha yesimanje, zasebenzisa izindlela ezintsha zesayensi of cwaningo hormone. izifundo ezihlukahlukene laboratory zasebenzisa izindlela ezihlukahlukene, kodwa ethandwa kakhulu iyona ndlela ELISA.

Ukuze zihlolelwe ama-hormone egilo kufanele kube ekuseni, esiswini esingenalutho. Uma umuntu usevele ukuthatha imithi esekelwe ama-hormone egilo, kufanele ukhansele ngalolo suku.