T3 - hormone yegilo: aphendule ngalokho, futhi ngesilinganiso ukuphambuka kusuka kuyinsakavukela

Abantu abaningi bayazi umsebenzi oyinhloko indlala yegilo kanye amahomoni ezivezwa ke, kubalulekile ukuba ukusebenza evamile umzimba. T3 ne-hormone okuthiwa (triiodothyronine) ungomunye wabo, futhi nenombolo "ezintathu" ngokucaca yayo uchaza okuqukethwe ngamunye-molecule salo zalelo nani elikhulu athomu e-iodine. Lakhiwa ukubola indlala lomunye hormone okuthiwa i - T4 uma wajinge wanamatsela ngu-athomu elilodwa iodine. Kokuba ngasebenzi ibe triiodothyronine T4 kuba ngokweqile asebenzayo. Ngakho-ke yini le hormone, futhi okuyiwona uyena obangela? Ake sizame ukuthola it out.

triiodothyronine Yeka ukuthi kubaluleke kangakanani?

T3 - hormone elawula umzimba womuntu amandla umzimba, ikhuthaza amandla kwamazinyo futhi ithumela ke emuva lapho idingeka khona. Ngenxa umsebenzi futhi izinzwa zakhe conduction luphakanyiswa kubantu. Okunye okubalulekile le hormone ukuze amathambo futhi uhlelo inhliziyo, ikhuthaza ukusebenza kwawo izinqubo umzimba kuzo.

Iyini I-T3 inani khulula?

Umdlavuza amaseli ziyakwazi ukukhiqiza lemali edingekayo triiodothyronine kakade nge-athomu omoya-ezintathu iodine. Engena phakathi kwemithambo yegazi, i-hormone sibopha ne amangqamuzana amaprotheni abathutha imithambo idluliselwe kwezicubu ukuthi abadinga umsebenzi wakhe. Nokho, inani elincane triiodothyronine, non-amaprotheni amangqamuzana, uhlala egazini. Lokhu i-hormone T3 khulula.

Ukuhlala khulula T3 ne-hormone okuthiwa lihambisana yokuthi elihlobene ne amaprotheni abizwa ngokuthi ama ezivamile. Lokho lemali kubhekwe ukuba eyabonisa ukuzimisela yegilo pathologies.

Okubizela ukuhlaziywa-hormone okuthiwa i-T3?

Ukuze sithole isimo indlala yegilo, i endocrinology ngempela unika isiguli nokudluliselwa kwazo ukuhlolwa kwegazi ku ezintathu-hormone okuthiwa i - TSH, T4 T3. Kungase kudingeke ukucwaninga amagama triiodothyronine kubhekwa njengento ebaluleke kakhulu njengoba kusiza ukunciphisa amaphutha zokuxilonga.

Ngokwesibonelo, amayunithi kaningi ezisebenza nge nodular goiter anobuthi ukukhiqiza kabusha ngokuthi i-T3 hormone. senani kungase kukhule futhi izifo ezifana 'isifo Graves futhi Graves' isifo. Uma umphumela ukuhlolwa kubonisa nokwanda okuphawulekayo inani triiodothyronine, odokotela okwatholakala "T3 toxicosis." isimo esinjalo iphathwa ngu izidakamizwa zemithi kuhle kakhulu.

T3 ne-hormone okuthiwa kuyinsakavukela

amazinga kukhona umsebenzi onjani okokusebenza kusetshenziswe kulolu cwaningo. laboratory ngamunye kwenza ukukhetha esivuna imishini ethile kanye reagents kunesidingo. Ngakho-ke akunakwenzeka ukuba unquma eside ezifana "triiodothyronine evamile." ubuningi yaso evamile kwenzeka ukuthi imiphumela eyatholakala ku inkomba umngcele embondelene (kusuka 3.15 kuya 6,25 pmol / l) kuboniswe kwifomu elabhorethri. Shaped ifomu ekhompyutheni, futhi ichaza imingcele imithetho kanye nenani le-hormone.

Ukwandisa-hormone okuthiwa i-T3

izimo eziningi sokugembula ahambisana ukwanda yegilo triiodothyronine. Ngokuvamile abantu angaluboni ukuphambuka kusuka kuyinsakavukela. Njengoba T3 - hormone esebenzayo kakhulu, okwandisa inani layo egazini kubangela lezi zimpawu ezilandelayo:

• Man nke ecasulayo, uba wethukile, abe nolaka kakhulu ngokushesha ube nexhala. isimo esinjalo kuhambisana umuzwa ukutubeka.
• Uqala i shaking iminwe.
• Isiguli singezelelwe kwenhliziyo, tachycardia, inhliziyo iqala ukusebenza ngezikhathi ezithile. T3 - hormone okukhuthaza ukuvela arrhythmia. isimo esinjalo umuntu azizwa kahle kakhulu futhi ngokuvamile ekhononda udokotela phezu ukungasebenzi inhliziyo.
• Isiguli uqala ngokushesha ukunciphisa umzimba.

Yokuncwaninga izinsimbi kanye namakhemikhali ngoba ukuzimisela triiodothyronine ileveli kunalokho inkimbinkimbi. Kukhona amacala lapho amaphutha laboratory. Ungakwazi ngaphezu kwalokho enze ukuhlola ukuthola amazinga ezinye hormone ezimbili - i-T4 futhi TSH. Uma imiphumela ibonisa ukuthi TSH kuyinto evamile, futhi T3 (i-hormone) liphakeme, ngokuvamile ibonisa iphutha.

Futhi, ukuhlaziya kuyoba udukisa Kuleso simo, uma ukubaluleka T4 evamile futhi TSH futhi T3 anda. Uma lezi imiphumela eyatholakala, kubalulekile ukuba kabusha ukuthatha ukuhlaziywa ngoba nge okwandisa-hormone okuthiwa i-T3 is ukwehlisa TSH ne-T4 luyanda.

Ukwehlisa i-hormone T3

amazinga triiodothyronine kungancipha uma kwenzeka ukukhiqizwa amahomoni ukuthi izindlala yegilo ukukhiqiza. Njalo is isimo lezi zifo ezilandelayo:

• Hashimoto sika thyroiditis - ubulwelwe lapho uhlelo umuntu sokuzivikela iqala ukubulala amanye amaseli yegilo. Yokutakula abakwazi, futhi ngokuvamile kuphele wonke umsebenzi ukukhiqiza ama-hormone.
• Hyperthyroidism - isifo enjalo kwenzeka ngemva ukungenisa imithi ethile okuhloswe ngazo ekwelapheni nodular futhi ekubhebhetselisa goiter anobuthi. Izindlela eziyingozi kakhulu kulo mongo kubhekwe njengento tireostatiki ngokuthi "tirozol", "propitsil", "Merkazolil".
• i-hormone ezingeni kungehlisa izinga ngemuva kokuhlinzwa eyenziwa kuwo wonke ukususwa indlala yegilo, noma nje ingxenye yalo.
• Ukwelashwa nge-iodine enemisebe futhi kunciphisa amazinga triiodothyronine. Lokhu ukwelashwa ihlose ukukhipha ngokukhukhumala kwentamo goiter anobuthi.
• i-hormone ezingeni lingase lehle ngesikhathi izindlela reception oqukethe semali iodine. Lezi zihlanganisa "Amiodarone", "Kordaron" nokunye.

Kodwa ngaso sonke isikhathi wehlise e-T3 ne-hormone okuthiwa egazini kubonisa khona isifo. Lesi simo kuyinto ejwayelekile kubantu besifazane, elinde umntwana, kusukela ngo-6 kuya ku-9 izinyanga yokukhulelwa.

You azi ukuthi amahomoni T3 ne-T4, futhi TSH kuyehla ilandelane ezithile. Eyokuqala njalo nokuncipha hormone i-T4 ezingeni, bese kuphela uwela triiodothyronine. Lokhu kwenzeka ngenxa izici umzimba, okuyinto hedged ngokufaka wehlise hormone i-T3, njengoba cishe 10 izikhathi ezingaphezu asebenzayo kuka-T4.

Ngenxa yalesi isiguli akunjalo sikuqaphela ngokugcwele imiphumela i-hyperthyroidism. Ngakho, nathi singakwethemba ngokuzimela ukunquma ukuthi iphutha laboratory senziwa. Uma imiphumela ukuhlaziya triiodothyronine ezingeni lehliselwa (futhi akunandaba, lena St T3 ne-hormone okuthiwa noma inani), ne-T4 futhi TSH kuthiwa ngaphakathi kwemikhawulo evamile, bese idatha kumuntu kumele kudingeke ukuthi uphinde isheke kwezinye laboratory kanye banikele ngegazi futhi.

isiphetho

Ngakho, ukuphambuka kusukela yinto evamile ukukhuluma ama-hormone egilo kuyinto zokugula sina okuyinto kuhambisana ushintsho isimo sezempilo. Ungase wamukele ukozela, eziya ziba zimbi inkumbulo futhi inkulumo, iqala ukudida umbono ngabesifazane akekho ukwahluleka nomjikelezo wokuya esikhathini. Lapho isikhathi sokwelashwa kuqalile uphatha ekulinganiseni amazinga ama-hormone, umsebenzi yegilo futhi wonke umzimba engena ukuze.