"Vasar 80": imiyalo yokusetshenziswa, incazelo yesidakamizwa, ubufakazi

Izwe lanamuhla elinesisindo esikhulu, ama-nanotechnologies kanye nokuphila okusheshayo kuholele ekutheni umfutho wegazi ophezulu unokweqile "osemncane". Uma sekudlule amashumi eminyaka edlule, lapho echaza ukuthi unjalo, udokotela wabona umuntu phambi kwakhe engaphansi kweminyaka engama-50, kodwa manje le nkinga ingaba nomuntu oneminyaka engamashumi amathathu ubudala.

Ukuze ukwazi ukugcina amagugu wegazi ejwayelekile, imithi eminingi ithuthukiswe. Lawa amaphilisi "Vasar".

Izingxenye eziyinhloko namafomu okukhululwa

Into esemqoka yale mithi ibizwa ngokuthi i-valsartan. I-microcrystalline cellulose, i-povidone ne-colloidal i-silicon dioxide, i-lactose monohydrate, i-magnesium stearate ne-talc isebenza njengabasizayo.

Njengoba kushiwo ngaphambili, lo muthi unikezwa abathengi ngendlela yamathebulethi ajikelezayo, agcwele igobolondo. Kuye okuqukethwe kokuqukethwe okuyinhloko (40, 80, 160 no-320 mg), imithi "i-Vasar 80", i-ejenti efanayo ene-dosage ye-160 ne "Vasar N", equkethe 320 mg we-valsartan ingathengwa kwinethiwekhi yekhemisi.

Ububanzi nokuphikisana

Ukwelashwa komfutho wegazi ophezulu - lezi yizibonakaliso eziyinhloko lapho ukusetshenziswa kwalo muthi kwenziwa khona. Okusho ukuthi ithebhulethi ye- "Vasar 80" ilawula imiyalelo yokusebenzisa ngokuthatha i-BP ukwehlisa hhayi kuphela nge-hypertension, kodwa futhi nanoma yiziphi izinkinga zesimiso senhliziyo ezizibonakalisa ngokwazo ngemuva kokuhluleka kwenhliziyo esimweni esingavamile.

Isidakamizwa sinokuphikisana okuthile kokungeniswa. Ungayimiseli ezigulini eziphethwe yisifo esinamandla sesibindi (i-cirrhosis kufaka phakathi) nokuphazamiseka ohlelweni lokuphuma kwe-bile.

Ngaphezu kwalokho, noma yiluphi uhlobo lwemithi ("Vasar 160", kanye nomthamo we-320 mg kanye no-80 mg) alukhuthazwa kulabo abanokukhubazeka ekusebenzeni kwezinso, kuhlanganise neziguli ezinikezwayo futhi zithola i-hemodialysis.

Futhi, abesifazane abakhulelwe, omama abahlengikazi nabantu abane-hypersensitivity kunoma yiziphi izingxenye ze "Vasar" akufanele bathathe le mithi.

Izicelo ezinokwenzeka, isilinganiso

Ngokuya ngobukhulu besimo sesiguli kanye nezici zomzimba wakhe, imithi ingenziwa ngendlela ehlukahlukene. I-160 mg ibhekwa njengedaysi ejwayelekile yansuku zonke edingekayo yokwelapha yomshuwalense. Uma ivolumu enjalo ingabonakali, iyashintsha ukuthatha i-Vasar N (320 mg), engadakwa ngesikhathi noma ihlukaniswe ngama-2 amanani ahlukanisiwe.

Kuziguli ezinezinkinga ezingapheli zenhliziyo, isilinganiso sokuqala singama-40 mg. Ingqikithi elandelayo ingu-80 mg. Kunoma yikuphi, imiyalelo yokusetshenziswa nge-"Vasar 80" isimo somuthi ukuthi kuyadingeka ukwandisa umthamo kusuka ku-80 kuya ku-160 mg ngosuku ngosuku kancane.

Imodi yokuphatha efanelekayo kabili ngosuku, ekuseni nakusihlwa, kuze kutholakale umphumela omkhulu. Khona-ke umthamo kufanele ulungiswe ukuze kusebenze okungenani. Umthamo omkhulu wansuku zonke u-320 mg, futhi awukwazi ukudlula.

Isihloko esihlukile siyi-infarction ye-myocardial kanye nesikhathi ngemva kwesigaba esiyingozi. Lapha, i- "Vasar" iqala ukuthatha nge-20 mg kabili ngosuku. Emasontweni ambalwa alandelayo, kancane kancane ukwandisa umthamo wezidakamizwa kuya ku-160 mg uhlukaniswe ngamanani amabili.

Amathebulethi athathwa kungakhathaliseki ukudla, ahlanzwe ngamanzi. Ukunquma isikhathi sokwelashwa kungukuthi udokotela olaphekile.

Ukubonakaliswa okungathandeki

Ngokuqondene nomuthi "u-Vasar 80", imfundo yokusetshenziswa ikwazisa ukuthi ngesikhathi sokwelapha, izifo zesinus paranasal kanye nomzila wokuphefumula ongaphezulu, njenge-pharyngitis, sinusitis, ingajoyina njengemiphumela emibi. Ngaphezu kwalokho, ukuthuthukiswa kwe-hypotension ye-orthostatic (ukwehla komfutho lapho isikhundla somzimba esikhaleni sishintsha) akupheli.

Kungenzeka futhi ukuthuthukisa ukwehluleka kwenhliziyo, ubuhlungu besisu kanye nesifo sohudo, ubuhlungu bomhlane, ukukhwehlela, i-myalgia, i-asthenia, i-conjunctivitis.

Isimiso sezinzwa esiyinhloko singaziveza ngokwaso ukulala, ukucindezeleka, i-neuralgia. Mhlawumbe ukuthuthukiswa kwe-hyperkalemia ne-thrombocytopenia. Ezimweni ezingavamile kakhulu, odokotela bakhuluma ngokuthuthukiswa kwe-angioedema, ukuphazamiseka kokusebenza emsebenzini wezinso, i-gastroenteritis.

Imiphumela yokudlula ngokweqile

Uma inani eliphakeme lomuthi "Vasar N", "Vasar 80", "Vasar 160" lidluliwe, imfundo (inani lemithi lizocatshangelwa ngezansi) lincoma lokhu okulandelayo. Njengoba ukudlula ngokweqile kungabangela ukuthuthukiswa kokuzizwa komzimba, okusho ukuthi, ngokuhambisana nomthetho, kuhambisane nesizungu, isiguli kumele sithathe isikhundla esingezansi, emva kwalokho izixazululo ezidingekayo ze-saline (parenteral) zinikezwa yona.

Ngenxa yokuthi i-valsartan ibophezela ngokuqinile emaprotheni egazi, i-dialysis ngeke inikeze umphumela omuhle.

Yini okufanele ngiyibheke?

Iziguli ezibhekene nesifo somzimba we-renal stenosis kanye nokuthatha amalungiselelo e-potassium kanye ne-potassium-sparing diuretics kufanele ziqaphele isimo sawo lapho sithatha "Vazar 80".

Imiyalo yokusetshenziswa ibuye yazise iziguli ukuthi ukukhululeka kwamathambo okudonswa kwemithi kungase kuholele ekuziphatheni kwesifo. Isizathu salesi simo sibonakala ekunciphiseni kokuqukethwe kwe-sodium futhi kwehla emtheni wegazi ojikelezayo.

Ngaphansi kokwengamela njalo udokotela, lezo ziguli ezifana nokuthatha i-Vazar ne- ACE inhibitors kufanele zibe khona . Ikakhulukazi iphathelene nezinyathelo zokuqala zokwelashwa kwe-CHF, ukwelashwa kwesifo se-cirrhosis nesibindi se-postinfarction.

Kumele kukhunjulwe ukuthi nganoma yiziphi izinqubo zesifo esibhedlela, umthamo wansuku zonke we-valsartan akufanele udlule u-80 mg. Ngokuphathelene nezingane nezingane, okwamanje azikho ulwazi mayelana nokuphepha nokusebenza kokusetshenziswa kwe "Vasar" yokwelashwa kwalezi zigaba zeziguli.

Uhlu lwamanani

Amanani omkhiqizo wezokwelapha ahlukahluka kakhulu ngokuya esifundeni, inani lesithako esisebenzayo esiqukethe iphilisi futhi, empeleni, inani lamathebulethi kuphakheji. Isibonelo, eMoscow "Vasar 80" (amathebulethi angu-30 ephaketheni) kuzodala umthengi ngesamba sama-ruble angu-240 kuya ku-350. Kodwa-ke, isidingo esithandwa kakhulu kubathengi, esinye isisindo esisetshenziswa kaningi (kunoma yikuphi, sikwazisa ngomuthi "Vasar 160"). Intengo yomuthi - amaphilisi angu-30 azobiza nge-ruble engu-450 kuya ku-500 - hhayi kahle kakhulu, kodwa ngesilinganiso esinqunyiwe samalanga angu-40, 80 mg azohlala isikhathi eside kunokuba umuntu athenge "u-Vasar 80" . Okungukuthi, kusukela kumbono wezomnotho, ukuthengwa kwephakheji engu-30 nge-dose ye-160 mg kunenzuzo kakhulu kunamaphilisi angu-30, kodwa ngesilinganiso se-80 mg.

Imibono mayelana nomkhiqizo wokwelapha

Ngokuqondene ne "Vasar 80", ukubuyekezwa ngaye kuye kokubili abasebenzi bezempilo kanye neziguli ziningi kakhulu. Isidakamizwa sezisungulwe njengethuluzi eliphumelelayo ekwelapheni kwegazi eliphezulu. "I-Vasar 160" nayo ayizange ibangele ukugxekwa.

Ngokusho kweziguli, kubonisa umphumela hhayi nje kuphela uma uthatha umthamo ogcwele we-160 mg, kodwa futhi kunciphisa ukucindezeleka kwegazi lapho uthatha isigamu noma ngisho nengxenye yesine yomthamo lapho izimo zesiguli zingekho futhi umuthi ubekezeleleke kahle.

Kukhona nokubuyekezwa okungalungile mayelana "ne-Vasar" ngomqondo wokuthi lesi sidakamizwa senze imiphumela emibi engadingeki. Inkinga evame kakhulu yi-hypersensitivity ngayinye kumakhemikhali, noma nge-dose ekhethiwe. Kulesi simo, kunconywa ukuba uthintane nodokotela, ngoba kuphela okubangela isimo sezokwelapha, kokubili uma kwenzeka ukhetha umthamo ongalungile, futhi uma ukhetha "uVasar", hhayi okunye.