Umuthi 'Selank ": ukubuyekezwa odokotela, yokusetshenziswa

Ukucindezeleka - iyingxenye yezimpilo zethu. Abanye basanda kuhlanganyela ngokushesha futhi ngokuphelele kithi, kuyilapho abanye jikisa iziyaluyalu kakhulu ngokomqondo noma Neurotic. Kuqede izimpawu ezinjalo kuyokusiza lesi sidakamizwa "Selank". Izibuyekezo bathi amathonsi aphumelela ekuphishekeleni ekulweni ukukhathazeka, kodwa ukuhlanganisa imiphumela izidakamizwa kumele kusetshenziswe Yiqiniso.

Ukwakheka izidakamizwa futhi ngendlela

It ikhiqizwa ngesimo acinene lehla ekwakhiweni "Selank". Incazelo nomuthi Siphawula nokuthi 1 ml isixazululo nge lokuhlushwa 0.15% equkethwe 1.5 mg esebenzayo ingxenye diacetate threonyl-lysyl-prolyl-arginyl-prolyl-glycine-proline.

Amaconsi tihlelwe e amabhodlela ne weThrojani ivolumu elula 3 ml. I isitsha ligcwele phama ebhokisini amakhadibhodi, lapho, ngaphezu imithi, kukhona incwadi yeziyalezo. Isisombululo uketshezi abangenalo umbala, kanye nephunga. Vial iqukethe amathonsi ayisithupha.

Umuthi ligcinwe ngaso t ≤ 10 ° C. Akumelwe simisiwe. Ithuluzi kufanele agcinwe endaweni epholile futhi amnyama kanye nezingane. Impilo - kweminyaka emibili kusukela ngosuku womshini.

Ungayisebenzisi ngale okungapheli. Khishiwe emakhemisi ngokuqinile on kadokotela. Itholakala ngaphakathi ruble, anamakhulu mahlanu.

imiphumela kwemithi

Izidakamizwa "Selank" - kuyini? Okokuqala, it is a zokwenziwa esikhundleni tafttsina peptide. Neyrospetsifichno enza isimiso sezinzwa futhi sibopha ukuthi receptor othize, lapho zitholakala kwi Ulwelwesi lwamangqamuzana ezinzwa.

Kuthinta exchange monoamines emotiogenic ohlelweni ubuchopho nemibukiso umsebenzi ubuchopho tyrosine futhi tryptophan hydroxylase enzyme anda. Serotonergic kuxhunywe esakhiweni, okuholela izinga kobuchopho serotonin ekunciphiseni izimo. Normalizes imisebenzi excitation futhi okusithiyayo. Kwandisa ukuzinza-neutron ekhanda, futhi silungiselela psyche womuntu ukuze abone ukuthi imithwalo esindayo.

I nomuthi ine anti-nokukhathazeka, umphumela anxiolytic. amathonsi acinene babe gipnosedativny futhi imisipha relaxant izakhiwo. Lapho ebonisa indlela lo umuthi nethonya elihle kokubili ngekhanda futhi nakognitivnogo uhlamvu. Kusho ekhuthaza inkumbulo, okuthuthukisa ukusebenza, umsebenzi, aqede ukucindezeleka, ukukhathala, ukucindezeleka futhi kwandisa ikhono lokufunda. It kwandisa izinqubo ugqozi nokubaluleka bezibona. It has Wegetotropona impahla. Kwandisa umsebenzi vegetative phakathi nokucindezeleka ngokomzwelo. Kulungisa lithathelwe izinqolobane zomzimba womuntu, it normalizes ukulala. Kuyasiza ukuhambisa indiza nokushintsha kwesimo sezulu, wonke sezigaba zezikhathi. Ikhipha podnarkoznye ukubonakaliswa.

Lapho ebonisa indlela lo "Selank" ohlangothini futhi akabubangeli imiphumela anobuthi ngisho nalapho ngokuphindaphindiwe okwandisa umthamo. Umuthi akwaziwa kuyacasula zendawo, embryotoxic, allergenic, izinga teratogenic. Ibonisa akanazakhiwo mutagenic. Amaconsi musa abangele ukuba umlutha kanye nokulutheka, kodwa ukukusiza ukuze usinde "yokukhansela" syndrome, okuyinto kubangelwa nezinye izidakamizwa.

Umuthi amehlo linikeza imiphumela emihle ku ekwelapheni glaucoma kanye optic nerve yoma.

Izidakamizwa "Selank" e Pediatrics ehilelekile ekwelapheni sakugcina ubuchopho ukungasebenzi. It is lisetshenziswe izingane ukunakwa kahle futhi hyperactivity. Futhi ukuthuthukisa lengqondo umsebenzi wokukhulisa ingane.

Pharmacokinetics

"Selank" (Izibuyekezo bathi umuthi kuyaphumelela ukucindezeleka nokukhathazeka ngokweqile) ine bioavailability ngokuphelele 92,98%. Ngemva kwemizuzwana engu-30 ngemuva yethula ukudlula acinene lehla isithako lingena igazi bumuncwa mucosa acinene. Ngemva kwemizuzu engu-Five, emakamu lomcebo asebenzayo iqala ukuncipha.

Metabolites nokuphathwa enjalo zomuthi ayikwazi ukutholwa. "Selank" ngokuphazima kweso ifika nezicubu ubuchopho futhi basakaza ngokushesha wonke umzimba. It luhlala ngefomu ezingaguquliwe nenhliziyo, izinso kanye esibindini.

Ugxile ekhaleni kufika ku-70%, bese lokhu ingxenye izidakamizwa kwasakazwa zonke kwezitho nezicubu. Umuthi lingena gazi ebuchosheni futhi isithiyo esinomhlapho. Lapho injected imvelo hematopoietic ukudleka ziphele. Libonisa uhlelo genitourinary.

Izidakamizwa "Selank": Ubufakazi

Umuthi kuboniswa ezibangela bokusungula-mnestic. Isisekelo ukusetshenziswa zikhulisa izimfanelo oluhambelana, kanye izinyathelo zokuvimbela yokukhathala, lapho umuntu baphoqelelwa ukuba basebenze isigqi okukhulu ngemva kwamahora ambalwa. Sebenzisa imithi e kuhlasimulise okulimala ebuchosheni nokuhlinzwa ubuchopho ngemuva kokuxinwa. Ncoma amathonsi at postanesthesia futhi astenonevroticheskih neziyaluyalu, ukukhathazeka ngokweqile nasekukhathazekeni-asthenic symptomatology, kanye neurasthenia nobunzima yokuvumelana umphakathi.

Zamehlo izinkomba kukhona yoma umbono, neuritis, ukufiphala kwamehlo.

Izingane kwezokwelapha ezingane ebekiwe ngemithamo emincane nobuchopho ukungasebenzi, uma kungekho ukunakekelwa, futhi kukhona hyperactivity.

Izimo

Izidakamizwa "Selank" (Izibuyekezo bathi zomuthi ngokushesha nangempumelelo ephatha ukucindezeleka) has Izimo ezithile. Lezi zihlanganisa hypersensitivity ukuba izinto lichaza ekwakheni amathonsi acinene, iziyaluyalu ingqondo ehambisana nesiphithiphithi.

Ban ukhonza sokukhulelwa, ukuncelisa futhi endocrine izifo.

Izidakamizwa "Selank": yokusetshenziswa

I amathonsi iphathwa intranasally kuphela futhi ngokushintshana e ikhala ngalinye. Iziguli ucelwa ukuba sihlale phansi futhi ngobumnene utshekisa ikhanda emuva. Ngemva instillation we ngomunwe izidakamizwa, bamba kafushane phansi ukudlula acinene. Kakhulu ukunciphisa ukusebenza kwe Ukukhetha indlela, wamanje kusuka ekhaleni.

Omunye nokuphathwa nomuthi kufanele kube ezintathu noma dropwise 300 mg isithako esisebenzayo. Umuthi iqondiswa ku kokubili ndima acinene. Uma imithamo ngasizathu simbe idinga ukuba lenyuke, lokhu kufanele kwenziwe emva kwemizuzu eyishumi nanhlanu emva isingeniso sokuqala. amazinga Kunconywe kukhona dropwise olulodwa 3-12 noma 300-900 mg isithako esebenzayo. esiphezulu I umthamo wansuku zonke kumele singeqi 900-2700 mcg. Uma udinga ukufaka eziningi amathonsi, yokwamukela uhlukaniswe kathathu. Le course ezingu-14. Kungaba liphindwe emva amasonto 1-3.

side effects kanye ukweqisa izidakamizwa

Ukulungiselela "Selank" (0.15%) ngesikhathi ukusetshenziswa isikhathi eside kungabangela imiphumela emibi. Lolu shintsho e bathanda, ukusabela iguliswa, hypersensitivity kuya izingxenye.

Ukusebenzisana neminye imithi

Khuluma kuphela mayelana nomphumela omuhle ukuthi umuthi "Selank" ukubuyekezwa. It akuphazamisi ukusebenza kwezinye izidakamizwa ezikucindezelayo isimiso sezinzwa esiyinhloko. Njengoba amathonsi acinene musa uxhumana neminye imithi.

Izixwayiso

"Selank" sintula gipnosedativny futhi imisipha relaxant izakhiwo. Umthelela izidakamizwa e ngabantu abaphilile belisebenzisa yinjabulo, ukukhathazeka, ukukhathala ngokweqile ethuthuka emva kwamaminithi ambalwa. Le nkathi ingahlala kusuka imizuzu 5 kuya ku-20.

Uma isimo alamu ihlala isikhathi eside, isikhathi sokwelashwa isukela enyangeni kuya enyakeni owodwa, futhi umphumela iyabonakala ngosuku lwesithathu.

Ngokwethulwa izidakamizwa phakathi share oyifunayo ezindleleni emsipheni olfactory uya ngqo ebuchosheni, lapho ilungelo has nomphumela ofiselekayo ngemizuzwana embalwa nje. Ngakho ungakwazi masinyane kuthinte isimiso sezinzwa zobuchopho, lapho izidakamizwa ingena indlela emfushane. Lapho beqeda instillation kwezidakamizwa baxhumana mucosa we ingaphakathi acinene futhi egazini ogeleza njengoba amangqamuzana ezinzwa e ebuchosheni. Ngokusebenzisa izinzwa olfactory kuyinto oqondile ubuchopho ukuxhumana mucosa acinene.

Le ndlela yokuphathwa ivumela isingeniso inani lemali lomcebo abakhuthele umzimba kuzohlala excitation izinqubo, ukunciphisa serotonin ebuchosheni. Uma lokhu akusho ukulimaza esiswini, isibindi nesisu.

Ukwelashwa lehla "Selank" kungenziwa kuhlangene antidepressant, amavithamini, magnesium B6. Lokhu kuzokhulisa kuphela umphumela, kodwa ngeke ukwandisa imvamisa okuba nemiphumela engemihle.

amathonsi acinene kungenziwa kuhlangene nophuzo oludakayo. Kulokhu, imithi kuzonciphisa ubuthi Ethanol nezinye nemiphumela ebuhlungu ubuchopho.

Ukusetshenziswa abantu abayimiqemane kungenzeka nge ukudana, ukukhathala, ukukhathazeka nokucindezeleka. Umuthi awukudla neuralgia uhlamvu ezahlukene futhi generalized abanenkinga yokukhathazeka.

Umuthi alisetshenziswa ngenkathi bekhulelwe nangenkathi bencelisa ngenxa yokuntuleka zokwelapha ngalesi sikhathi.

Drops futhi angase ukwamukela abantu kungakhathaliseki umsebenzi kanye nohlobo lomsebenzi. Lapho ukwelashwa sekudlulile akuyona lokuhlushwa kahle kanye nokudidiyela ukunyakaza, okuyinto ebaluleke kakhulu ukwazi nabashayeli izimoto kanye nabantu abakuphila umsebenzi lihlotshaniswa emakamu eliphezulu ukunakwa nesivinini ukunyakaza.

analogs

Bathi ngokushesha kususa ukukhathazeka nokwesaba izidakamizwa "Selank" ukubuyekezwa. Photo nge umfanekiso ibhodlela ngezansi.

Okwamanje, azikho analogue kwesakhiwo ngoba "Selank" abangase babe into esebenzayo efanayo.

Uma izidakamizwa ngasizathu simbe akazange angene ke onguchwepheshe kuzosiza esikhundleni sakhe phezu imithi, property okuyinto akusizi kuso.

Uphenyo odokotela

Ochwepheshe umbono omuhle kakhulu imithi "Selank". Uphenyo odokotela bathi neurasthenia ezinhle uyawathena, ubuyisela ukulala, kwehlise neluvalo kususa ukucindezeleka. It ezinqunyiwe ekwelapheni uhlamvu Neurotic isethi izifo futhi uma kukhona "khansela" syndrome ngemva kokusebenzisa izinsiza ukuba ungaguli kakhulu, njengokuthi "Fenazepam". Bakubheka njengenjabulo ngempela yithuluzi elinamandla. A yi enhle banikezwe amathonsi ekwelashweni.

Odokotela uqaphele ukuthi izidakamizwa ayiluthi. It uba ngokuphazima kweso futhi akusho siyekele imihlola ezimbi. Ukweluleka emva kokuthenga ukugcina esiqandisini.

Kodwa akubona bonke ochwepheshe walidumisa izidakamizwa. Ezinye musa uthemba amathonsi acinene futhi bathi bangakwazi ukubhekana ukugula omnene kuphela. Futhi ukuyibiza ikhambi cishe i-placebo. Kuthiwa izifundo zokwelapha sina sezenziwe emuthini "Selank" impendulo evela kodokotela.

Mbiko iziguli imithi

Uphenyo "Selanc" babe kuphela omuhle futhi singathathi hlangothi. Ngamanye amazwi, abantu abasiza lo muthi, basutha ne umphumela. Acinene amathonsi ngokushesha asuswe ukukhathazeka kokuthikamezeka, ubuthongo kwesejwayelekile, ukwandisa ukusebenza kahle, ukuqeda ukudla. Abantu ngemuva ukuzisebenzisa wafuna smile bese uyakhululeka ujabulele ukuphila. Abanaso ukucisha kumqashi, izihlobo nabangani. zisuswe kalula ukucindezeleka eyathatha ngesonto ezingaphezu kweyodwa, basizwa ukuba babhekane ukukhathazeka nokwesaba izidakamizwa "Selank".

Ukubuyekezwa ezikushoyo nguye nomthelela omuhle kakhulu kumemori, ukukhalipha izingane. Emva kokuthola amathonsi izingane ziye zaba lula ukuzumeka futhi ukulala namandla, zisamukele kakhudlwana ulwazi olusha.

Izibuyekezo eziphakathi bathi ithuluzi akusebenzi, kuyabiza futhi ibhodlela elincane, ozobakhona zokusebenza ezimbalwa nje.

"Selank" - isizukulwane esisha imijovo. Kuyasiza ukwazi ukubhekana nobunzima ekuphileni nezinto ukwelapha izifo eziningi. Siyabonga esenzweni yayo, abantu abaningi bakwazi ukujabulela ukuphila futhi singanqotshwa yithemba, usizi nokukhathazeka.