Ukulungiselela "Levocarnitine": imiyalo yokusetshenziswa, i-analogues, ukubuyekezwa

Ngeke siphuthele uma sithi isihloko sokulahlekelwa kwesisindo kanye nokwehlisa isisindo esisodwa emhlabeni namuhla. Kunezidakamizwa eziningi ezakhiwe ukuze zisuse ngokushesha isisindo esiningi futhi ngaphandle kwehla izinga lempilo. Kodwa-ke, ukungaziqondi izinqubo "ezibangela" emzimbeni ukuhlukaniswa kwamaseli amafutha, kunzima kakhulu ukulahlekelwa isisindo. Enye yezinqubo ezisebenza ngempela ezingeni lamaselula yiLevocarnitine. Imikhiqizo yezokwelapha, eyilungu layo, isetshenziselwa kakhulu ezemidlalo, imithi, ukwelashwa kwesisindo.

Mayelana nokulungiselela

Iyiphi imithi yokwelashwa yokwelapha "Levokarnitin"? Imiyalelo yokusetshenziswa ibonisa ukuthi i-powder emhlophe ephuza amanzi egcwala kalula emanzini, kodwa ayinakukwazi ukuphuza utshwala.

I-Carnitine ayicatshangwa ngokuphelele nge-vitamin, ibizwa ngokuthi i-vitamin-like substance. Kodwa-ke, kuma-amino acids, nayo ayikwazi ukulinganiselwa ku-100%, i-amino acid derivative. Konke ngoba akayena umsoco, okungeke kube khona ukungaxhunywanga umzimba womuntu.

Izakhiwo eziwusizo

Iyini inzuzo yeLevocarnitine? Izakhiwo zalo zihlukile ngoba zikhuthaza ukwelashwa kwe-omega-fatty acids: i-linolenic, i-palmitic, i-linoleic, i-arachidonic ne-oleic. Eqinisweni, idlulisa ama-acids ama-acids amade amade ngama-double membrane we-mitochondria. Lapho, ngenxa yalokhu, ngenqubo ye-biosynthesis kukhona ukukhululwa okukhulu kwamandla. Ngaphezu kwalokho, izidakamizwa ezine-levocarnitine zithuthukisa ukukhululwa kwemikhiqizo yemetrikhi emifushane kusuka mitochondria. Ngakho-ke, ilawula izinqubo zokusebenzisa umzimba ezinomzimba emzimbeni.

Isenzo sempilo

Iyini umphumela emzimbeni we "Levocarnitine"? Imfundo ithi ijwayelekile ukuba i-fat metabolism, ukwandisa ukukhuthazela, inomphumela we-anabolic, ilawula amaprotheni umzimba, ikhuthaza ukukhula kwemisipha yomzimba. Ngenxa yezinto zayo ezingezansi, lesi sidakamizwa siyadingeka ngesikhathi sokuvuselelwa ngemuva kokulimala kanzima noma imisebenzi yangaphambilini. Yena, ngokusho kokubuyekezwa, usizo olungcono kakhulu lokubuyiselwa ngemuva kokuzikhandla komzimba okwandisiwe, lisetshenziselwa ukwandisa ukukhuthazela nokufeza ukusebenza okuphezulu ezemidlalo.

"I-Levokarnitin" ine-anti-steroid effect, okungukuthi, iyasiza labo abanesifo se-hyperthyroidism. Ngaphezu kwalokho, kuphawulwe impahla yayo elwa nama-antihypoxic, evumela ukuphatha ngempumelelo izifo ezihlobene nokungabi khona kwe-oksijini ezintheni nasezigumbini zangaphakathi.

Izinkomba zokusetshenziswa

Kule mithi "Levokarnitin" imiyalelo yokusetshenziswa ihlale ihlanganiswe, futhi ungayisebenzisa ukucacisa ukuthi iziphi izinkomba ezihambisana nalokho okulinganiselwe.

Isidakamizwa sinikezwa ekhemisi ngaphandle kwemithi kadokotela, kepha ukwelashwa okungathí sina kumele kube yiziqondiso zodokotela, uhlelo lokuthatha, ukulinganisa nokuqapha inkambo yokwelapha. Ngakho-ke, kunconywa ukuba ungahlanganyeli emithini yokwelapha futhi uthathe izidakamizwa ngokweqile ngokusho kwezokwelapha. Kungenxa yokuthi "i-Levocarnitine", njenganoma imuphi umuthi, uyakwazi ukwenza umonakalo uma ithathwa ngokungalawuleki. Ngokwayo, akulimazi, kodwa kungabangela ukusabela komzimba ngabanye, ikakhulukazi ngokulandelana kokuthatha ezinye imithi.

Kunconywa ukuthi usebenzise ukwelashwa okuyinkimbinkimbi kuma-micropediatrics kanye nezingane zokwelashwa ngokubambezeleka ekuthuthukiseni, ukungabi nesisindo, ukukhula. Ekunakekelweni kokubuyisela ngemuva kokungenelela kokuhlinzwa, ukulimala noma izifo ezimbi.

Isetshenziselwa ukuqeqeshwa kwezemidlalo okuzayo, njengoba kusiza ukuthola insimu ngokushesha.

"Levocarnitine" iboniswa ngokukhethekile kubantu abaneminyaka yobudala yokuthatha umhlalaphansi, ngalesi sikhathi, ukusekelwa kwemisipha ebuthakathaka, izitho zangaphakathi nobuchopho kuyadingeka ikakhulukazi. Ngokusho kwabantu asebekhulile, labo abathatha izidakamizwa kakhulu bathuthukisa ikhono lokugxila, khumbula ulwazi.

Njengoba kunikezwa ukuthi i-carnitine iklanyelwe kusuka kumikhiqizo yamaprotheni enjengenyama nenhlanzi, labo abahambisana nemigomo yokudla kwemifino kungase kube nengozi enkulu, ngakho-ke banconywa ukuthatha iLevocarnitine.

Isetshenziselwa ukwelapha i-dystonia yemifino yemvelo, ekwelapheni kokukhathala okujwayelekile, ukukhathala okungapheli.

Izimpawu zokuntuleka kweLevocarnitine

Iziphi izimpawu ezibonisa ukuthi umzimba awunakho into efana neLevocarnitine? Imiyalo yokusetshenziswa izobonisa ukuthi yiziphi izimo eziboniswayo. Ngaphezu kwalokho, kufanelekile ukunaka:

• Ukuqoqwa kwamafutha;
• Ukukhathala okusheshayo, ukuzithemba, ukukhuthazela kwehle;
• Ezinganeni ezincane, ukuxilongwa "kuyinto evame ukugula ingane", labo asebekhulile banciphile ekusebenzeni kwezemfundo;
• Ukudikibala ekuthuthukiseni okujwayelekile kanye nengqondo, ukukhula ezinganeni;
• Ukucindezela kwe-Hypotonic (ephansi);
• Ukucindezeleka, imizwa yokucindezeleka jikelele.

Yebo, singasho ngokuqiniseka ukuthi uma umuntu engadli inyama, usebenzise izinhlanzi ngokungajwayelekile, khona-ke unesifo se-levocarnitine emzimbeni. Ngoba izakhi zifika ngokudla ngevolumu ye-100-140 mg, kuyilapho ukuhlinzeka kwezicubu kuthuthukisa ngokungezwa kuka-500 mg. Ukudlula umthamo wansuku zonke ngaphezu kwe-2 g akukhuthazwa ngisho nabagijimi, lokhu akuthinti ukusebenza koqeqesho.

Ungathatha kanjani iLevocarnitine?

Amanani, uhlobo lomuthi kanye nobude benkambo kunqunywe udokotela oya khona. Kumele acabange ukungena kwezinye izidakamizwa, indlela yokuphila, ukuxilongwa okuhambisanayo.

Imithi ngesimo sesiraphu ayidingi ukuhlanzwa nge-liquid, kodwa kuyamukeleka ukuyiphuza ngamanzi. Ukwamukelwa kwe-prophylactic kubantu abadala kugxile izikhathi ezingu-3 ngosuku ngo-5 ml.

Uhlelo lokuthatha isiraphu "Levokarnitina" yezingane:

Isidakamizwa esithi "Levokarnitin" sidakwe inkambo yezinsuku ezingu-30 izikhathi ezingu-2-3 ngosuku.

Uhlelo lokuvunyelwa kwabadlali, ababhekene nokuqeqeshwa okujulile kanje.

Nika isiraphu, 15 ml ngesilinganiso esisodwa, mhlawumbe ekuseni noma ngokushesha ngaphambi kokuqeqesha. Isikhathi sokuthatha lesi sidakamizwa - kusuka ezinyangeni ezingu-1-1,5, bese udinga ukuphumula okungenani izinsuku ezingu-14. Inkambo iphinda iphindwe uma kunesidingo.

Umuthi wefomu le-capsule noma ithebhulethi uthathwa lonke, ngenani elanele lamanzi. Isilinganiso sabathameli - kusuka ku-500 mg ukuya ku-1500 mg ngesikhathi esisodwa.

Ukufana kwezidakamizwa

Ingabe kukhona amalungiselelo afanayo okwemvelo okudayiswayo afana nesenzo esithi "Levocarnitine"? Ama-analogue angatholakala ngaphansi kwamagama:

• "Carniten";
• "Elkar";
• "Cartan";
• "Metacartin";
• I-Carnitone;
• "Iyadlula".

Ama-analogue angahlukaniswa yi-proportion yezinto ezisebenzayo ze-levocarnitine kanye nendlela yokukhululwa. "I-Elkar" yisisombululo se-20% ebhodleleni elimnyama lesilazi noma ehlanganiswe kuma-tubes ane-7.5 amagremu. "Inest" idayiswa ngesimo se-ampoules for injection yangaphakathi nesigxathu, ehlanganiswe emabhokisini amakhadibhodi ezinhlamvu ezingu-5 noma ezingu-10.

"Carnithen" ne "Cartan" - ngamabhalters, ngaphakathi kwama-4-5 ampoules weklasi lamnyama ingilazi engu-10%. "I-Metacartin" ngokulula, njengezifanekiselo zangaphambilini, itholakale emithini emibili - ama-ampoules ama-5 noma angu-10 weglasi elimnyama e-blister, efihliwe ebhokisini lekhadibhodi. "I-Carnitone" iyatholakala ebhodleleni elenziwe ngilazi emnyama ngendlela yesisombululo se-40% noma ngendlela yamathebulethi agcwele amabhulashi ezinhlamvu ezingu-10. Ebhokisini lezidakamizwa "Carnitone" amabhalansi amabili amaphilisi.

Kusho ukulahlekelwa isisindo

Ingabe udinga i-levokarnitin yokulahlekelwa isisindo? Njengoba sesishilo kakade, ngesilinganiso esinganele emzimbeni, ama-fatty acid akwazi ukungena phakathi kwezindonga ezimbili zegundane le-mitochondrial futhi ashise lapho. Ukuthatha lesi sidakamizwa "Levocarnitine" ukuze unciphise isisindo somzimba, udinga ukukhumbula umphumela owodwa - ukwanda kwesidlo ngenxa yamandla akhule. Ngakho-ke, uma ungaxhumi ukulayisha kwamandla okusebenzisa i-ATP eyedwa eceleni kwama-fat depots, khona-ke kukhona ingozi enkulu yokuthola isisindo.

Ngakho-ke, uma umgomo ukuphuza isisindo ngokushesha, khona-ke umthamo owodwa weLevocarnitine ngeke ukwanele, ukushintshwa okuvamile kwe-aerobic kanye namandla, kanye nokudla okunomthelela omkhulu weprotheyini, kuyadingeka. Kule nkathi, ukuqeda ngokuphelele ukudla kwamafutha, ushukela nokudla okusheshayo.

Ukubuyekezwa njengendlela yokunciphisa isisindo somzimba

Ngingakwazi yini ukulahlekelwa isisindo ngokuthatha iLevocarnitine? Imiyalo yokusetshenziswa, ukubuyekezwa kwalabo abathatha izidakamizwa, bathi kuyasiza ngempela ukunciphisa isisindo somzimba. Cishe angu-90% kulabo abavivinye isimangalo sezidakamizwa ukuthi bakwazi ukulahlekelwa isisindo. I-10% esele yilabo abahlala besisindo sabo. Kungani lokhu kwenzeka? Izizathu ziyizinto ezimbili, okokuqala ukuthi kukhona ukuphendula komzimba komuntu ngamunye, kanti okwesibili - ukungenisa nokusetshenziswa kwamandla akulinganisani ngokwanele, okulula, akukho okwenziwe ngokomzimba okwanele.

Ukuqhathaniswa nemiphumela emibi

Isidakamizwa asinakho ukuphikisana, ngaphandle kwalabo abangasenza khona isimo. Isibonelo, angeke isetshenziselwe izifo ezinzima zesigcawu sesisu, sibonise ukusabela kwe-allergen.

Ungasincoma ukusetshenziswa kwe "Levocarnitine" ngaphandle kokuqokwa komzimba wezifo ngesikhathi sokukhulelwa, nakuba umsoco ngokwawo uwusizo lapho uphatha futhi ukondla ingane. Umthamo kufanele ucebise isikhathi sokubeletha. Njengomthetho, ngalesi sikhathi, umama wesikhathi esizayo uthatha i-vitamin-mineral complex, equkethe i-carnitine ngendlela elinganiselayo.

Imiphi imiphumela emibi ingabe umuthi "Levocarnitine" ubangele? Ukubuyekezwa kokudlula ngokweqile nemiphumela emibi kungavamile kakhulu. Ngokuyinhloko, zihlotshaniswa nokubekezelelana komuntu ngesimo sezidakamizwa se-L-carnitine.

Kungani izidakamizwa zokudlula ngokweqile zingaphansi? Into ewukuthi i-Levokarnitin iyisisindo esinempahla e-homeostatic, okungukuthi, isisindo esingaphezu komzimba sisuke sisuka emzimbeni sisodwa ngaphandle kokulimaza umzimba. Kunoma yikuphi, uma kukhona ukusabela okungalungile kokuthatha imithi ngendlela yokucabangela, ukuhlanza, isifo sohudo, ukuhlukunyezwa nokunye okunjalo, isidakamizwa kufanele simiswe ngokushesha.

Uma kusetshenziselwa ukuphathwa okunamandla, uma umuthi uphathwa ngokushesha kakhulu nge-dropper, izinzwa ezibuhlungu eceleni kwe-vein ezenzeka ngemuva kwenqubo kungenzeka.

Ukuxhumana

Uhlobo olunjani lwemithi lingase ihlanganise ne-Levokarnitin? Imiyalo yokusetshenziswa ibonisa amacala okuqoqwa kwe-carnitine kwezicubu, ngaphandle kwesibindi, uma kuthathwe i-glucocorticoids. Njengoba kunikezwe ukuthi izidakamizwa zinempahla ye-anabolic, uma uthatha izidakamizwa ezifanayo, umphumela we-anabolic we-Levocarnitine uzoba khona.

Khumbula ukuthi "i-Levokarnitin" iyabuyekezwa njengethuluzi eliyisimangaliso lokulahlekelwa isisindo nokuqina okukhulayo kuyafaneleka. Lokhu empeleni kusebenza ezingeni le-intracellular biosynthesis yezakhi, kodwa njengendlela yokukhuthaza ukulahlekelwa kwesisindo ngokushesha, isebenza ngokuzivocavoca nokudla kwamaprotheni.