"Moxonidine": yokusetshenziswa, ngempela

Uyini elaphe "Moxonidine"? Yokusetshenziswa kwaleli thuluzi, izibuyekezo ngakho, Izimo, futhi analogs zichazwe ngokuningiliziwe kulesi sihloko. Ngaphezu kwalokho, sizokutshela eliphathelene nelungiselelo lokho sisuke sicabanga senzelwe, uma unalo yini imiphumela emibi kanye nefomu lapho ikhishwa.

Ukuma kanye nendlela okwakheke ngayo izidakamizwa

kungenzeka ukuthenga le izidakamizwa "Moxonidine" ngayiphi indlela? Lesi sidakamizwa kuphela ithengiswe ngesimo amaphilisi. elementi wabo asebenzayo kuyinto into ezifana moxonidine. Ngokuphathelene izingxenye ezengeziwe ezihlobene nalokho cellulose microcrystalline, uwoyela ocolisekileyo, Aerosil A-380, hydroxypropylcellulose, magnesium stearate futhi Tween-80.

Tablets zidayisa iphakheji amakhadibhodi. Omunye iphakheji kungenzeka 98, 60, 56, 42, 40, 30, 28, 20, 14 kanye amaphilisi 10.

I izakhiwo kwemithi zomuthi

Kungani ngidinga imithi "Moxonidine" ukwenzani? Yokusetshenziswa uthi lokhu ukulungiselela kuyinto izidakamizwa antihypertensive. indlela yayo yesenzo itholakala lokuthi ukuthi asebenzayo izidakamizwa izindlela kuthinta izixhumanisi emaphakathi wegazi isiqondiso. Ngamanye amazwi, moxonidine - imidazoline yokwamukela agonist kuyinto (ikakhulukazi).

Umuthi kuvimbela umsebenzi isikhungo vasomotor, ukunciphisa umphumela ukwehla nozwela ohlelweni senhliziyo nemithambo yegazi. Ingcindezi (diastolic futhi systole) incipha kancane kancane.

nomuthi kubhekwe yithi ihlukile kwezinye ejenti antihypertensive sympatholytic e ukuthi usalelwe ziyezwana oluncane-alpha-2-adrenoretseptoramm. Lokhu kuchaza ematfuba eliphansi nomlomo owomile kanye ukupholisa.

Asinakusho ukuthi moxonidine kungandisa insulini ukuzwela Inkomba (cishe 21 amaphesenti) kubantu ukukhuluphala.

Pharmacokinetics zomuthi

Lapho izidakamizwa amuncwa umzimba, "Moxonidine"? isicelo Umsebenzisi uthi ngemuva kokuthola nomuthi ngokushesha futhi cishe ngokuphelele ugxile elingenhla ipheshana wokugaya ukudla.

Bioavailability (eliphelele) we thuluzi amaphesenti angu-88. Ubuningi esiphezulu kufinyelelwa emva kwemizuzu ayisithupha nanhlanu. Kulokhu, ukusetshenziswa ukudla akukho ukusebenza ngomhla ka-pharmacokinetics timphawu asebenzayo ayizange.

Ukuxhumana amaprotheni igazi imayelana 7.3%. I metabolite enkulu Moxonidine Moxonidine izenzo emzimbeni, futhi guanidine nemikhiqizo.

Ingxenye-ukuphila moxonidine futhi metabolites walo wawenziwe 150 kanye 300 amaminithi ngokulandelana.

Ngemva kokungenisa amahora angamashumi amabili nane kwezidakamizwa excreted ngu izinso emqulwini ka-90%. Futhi, ketshezi asebenzayo uyaphuma bese ngokusebenzisa emathunjini.

Izinkomba ngokusetshenziswa idivayisi yezokwelapha

Kwezinye izimo, prescribers 'Moxonidine "? Ukusetshenziswa kwalesi izidakamizwa ikhonjiswa kuphela uma zokugula ezifana unomfutho wegazi ophakeme.

Izimo ukusetshenziswa idivayisi yezokwelapha

Kwezinye izimo, odokotela musa akunikeze imithi ukuze Moxonidine zeziguli zabo '? Yokusetshenziswa yalesi izidakamizwa iqukethe hhayi uhlu olude kakhulu Izimo. Cabanga-ke manje.

Ngakho contraindications ukusetshenziswa "Moxonidine" ukulungiselela yilezi ezilandelayo izici:

• uzwakalise AV-block 2 no-3 degrees, Sss;
• bradycardia (ngaphansi kuka-50 ngomzuzu);
• yokweva eshumini nambili neminyaka yobudala zezingane (iminyaka engu-18);
• ezingamahlalakhona futhi ukwehluleka oyingozi inhliziyo;
• ingane ukusuthisa isikhathi;
• Hypersensitivity kungxenye asebenzayo.

Umuthi 'Moxonidine ": yokusetshenziswa

Nobufakazi ngalokhu nomuthi izokwethulwa ekupheleni isihloko. Manje ngifuna ngikuxoxele kanjani ukusebenzisa izidakamizwa kahle phambi kwethu.

Izidakamizwa "Moxonidine" kungaphakathi kuphela. Isikali ekuqaleni kuka ukwelashwa kufanele kube 200 micrograms kanye ngosuku. Ngokuhamba kwesikhathi, ungathatha micrograms 400.

Kudinga i ukulungiswa ngazinye lemali nsuku zonke imithi kuncike tolerability yokwelapha izidakamizwa. Ngokusho imiyalelo, umthamo esiphezulu nomuthi ngelanga kuyinto 600 mg (izigaba ezimbili).

Ezigulini ezine-esingamahlalakhona kwezinso (nokulinganisela ezinzima), futhi abantu abaku- hemodialysis, umuthi iqondiswa e isamba 200 mg kanye ngelanga. Uma kudingekile (ngokukhuthazela ezinhle), umthamo ecacisiwe zingandiswa kuya esiphezulu (okuyi-400 mg).

imiphumela emibi ngemva kokwamukela nomuthi

Ingabe imiphumela emibi izidakamizwa "Moxonidine"? Nobufakazi ngaye bathi ngezinye izikhathi imithi empeleni kubangela Ukuwohloka impilo. Cabanga uhlu side effects iqukethe imfundo:

• isimiso sezinzwa (central): ikhanda, yokufikelwa, isiyezi, futhi somnolence.
• ipheshana wokugaya ukudla: ukuhlanza, ezomile umlomo, uhudo, dyspepsia nesicanucanu.
• Isimiso senhliziyo nemithambo yegazi: bradycardia, iconsi abashe blood pressure, hypotension orthostatic.
• Skin nezicubu ongama iziyaluyalu: edema angioneurotic, pruritus futhi ukuqubuka kwesikhumba.
• zengqondo: uvalo nokuqwasha.
• Uxhaxha iziyaluyalu isitho sokuzwa: enkeneneza ezindlebeni (kwenzeka kakhulu kuyaqabukela).
• Uhlelo zemisipha: yobuhlungu beqolo, ubuhlungu entanyeni.
• Common side effects: edema neuropathy asthenia.

Njengoba ubona, "Moxonidine" amaphilisi angabangela ukuwohloka kwesimiso lesiguli. Uma imiphumela emibi kuthiwa ke umthamo imithi kufanele ayisekho.

kusho nokuxhumana neminye imithi

Ukuze izidakamizwa "Moxonidine", "Moxonidine Sandoz" nezinye analogue izidakamizwa wasiza nesineke futhi akazange kumenze engozini eqhubekayo, kufanele kuthathwe kuphela kadokotela. Ngemva reception ngesikhathi esisodwa ithuluzi nezinye imithi baxabane engadingeki. Yini kahle hle, sizobheka manje.

ukusetshenziswa kwesikhathi esisodwa izidakamizwa "moxonidine" ne-ejenti efanayo antihypertensive kungabangela umphumela okufakiwe.

Antidepressant (tricyclics) ukunciphisa nekusebenta izidakamizwa antihypertensive isinyathelo emaphakathi. Kule ndaba, kungukuthi Kunconywa ukuba isetshenziswe ngokuhlanganyela into ezifana moxonidine.

contact Ubuke le nomuthi kalula babhebhethekisa imiphumela izidakamizwa, tricyclic antidepressant, kanye ethanol, hypnotics futhi sedatives.

Ingqikithi asebenzayo kuyinto nomuthi ngokulinganisela attenuated ngcono imisebenzi engqondweni yethu abantu kanyekanye ukuthola lorazepam.

Nakuba ukuqashwa kukaNksz "Moxonidine" izidakamizwa "benzodiazepine" kungase kuzenze zibe namandla ukupholisa nemikhiqizo lakamuva.

Ochwepheshe bathi Moxonidine is etholwe uketshezi ijabulise. Ngokuqondene nalokhu-ke akufanele isetshenziswe nge izidakamizwa nazo zihlukaniswa uketshezi ijabulise.

Isikhathi esesibelethweni kanye lactation (nokukhulelwa kanye lactation)

Ingabe inkathi sokukhulelwa ukuthatha imithi "Moxonidine-LF"? Imiyalelo izidakamizwa iqukethe ulwazi lilawulwa futhi izifundo ezanele mayelana nokuphepha imithi kubhekwe ngesikhathi sokukhulelwa lwenziwe. Yingakho it is hhayi Kunconywa ukusebenzisa lesi sigaba iziguli.

Asinakusho ukuthi izidakamizwa "Moxonidine" akufanele isetshenziswe ngesikhathi ibele. Lokhu kungenxa yokuthi kuqokonyiswe nge ubisi lukamama. Uma ngesikhathi lactation izidakamizwa isengakabekwa, ukuncelisa ke kufanele inqanyulwe.

Ngo inqubo izifundo (lokuhlola) e izilwane, kwatholakala ukuthi nomuthi kuthinta embryotoxic.

isiqondiso Specific on ukusetshenziswa imithi

Ngokusho imiyalelo enamathiselwe, ngenkathi ukusetshenziswa kwezidakamizwa "Moxonidine" Kufanele uqaphele ikakhulukazi. Ikakhulukazi kumayelana wodwana iziguli. Yikuphi, sichaza manje.

ngokuqapha ikakhulukazi uma sisebenzisa "Moxonidine" nomuthi ukuze babonwe in iziguli AV-ukuvinjelwa 1st degree. Lokhu kungenxa yokuthi abantu abanjalo kunobungozi olukhulu bradycardia.

Futhi ethola izidakamizwa okufanele iqhutshwe ngaphansi kokuqondisa kukadokotela esiqatha. yenhliziyo Umthambo isifo, ukungasebenzi kwezinso futhi angina engazinzile. Leli qiniso kungenxa yokuthi okuhlangenwe nakho usebenzisa izidakamizwa ne kwezinso enjalo alanele.

Uma ufuna ukukhansela ukusetshenziswa ngesikhathi esisodwa izidakamizwa "moxonidine" ne-beta-blocker, kuzomele uqale ukhansele sokugcina, ngemva kwezinsuku ezimbalwa - yesibili.

Kuze kube manje akukho bufakazi ukuthi ukuyekisa "Moxonidine" izidakamizwa kuholela blood pressure. Nokho, naphezu ukuthi ochwepheshe batusa nokho ukuba sengeta out imithi. I Isikali kumele kungancipha past amasonto amabili.

ngabe yezidakamizwa ithinta ikhono ukushayela imoto yezokuthutha?

Phakathi nenkathi zokwelapha nge "Moxonidine" abantu kudingeka baqaphele ngokukhethekile lapho ukwenza imisebenzi eyingozi, kanye ngenkathi ushayela izimoto. Lokhu kungenxa yokuthi i-izidakamizwa Zingaphazamisa reception okuhlushwa futhi lengqondo ukusabela.

Analogs, futhi izindleko zomuthi

Thenga izidakamizwa "Moxonidine" kule ekhemisi unga ngaphandle kadokotela. Izindleko zalesi izidakamizwa kuqhathaniswa ongaphakeme. Per iphakethe, equkethe amaphilisi 14 kuzodingeka akhokhe ruble Russian mayelana 115-135.

Uma sisuke sicabanga umuthi ungezi, noma nje zehlulekile ukuyithola ekhemisi, nangemva kokuba yokudluliselwa kuchwepheshe, lona wamuva siphoqelekile ukuthi bancome Analogue izidakamizwa. Phakathi kwalezi nemithi Ngithanda ukugqamisa esilandelayo: "Fiziotenz", "Moxonidine-C3", "Moksarel", "Canon of Moxonidine", "Moksoniteks", "Moksogamma", "Tenzotran" nokunye.

Thatha imali kumele kube ngokuqinile ngokuvumelana isincomo udokotela. Futhi, ngaphambi ukusetshenziswa imithi kumele ayejwayele imiyalelo enamathiselwe.

Umuthi 'Moxonidine ": ukubuyekezwa kodokotela kanye neziguli

Ochwepheshe bezifo, lokhu izidakamizwa siyasebenza kakhulu ophakeme wegazi. Lo mbono olwabiwa iziguli. Nokho, abanye babo bakhononda ukuthi ngemva kokuba enqobe izibhebhe emva kwesikhashana babonisa komzimba okufana ikhanda, nomlomo owomile, uvalo nesicanucanu. Kulokhu, odokotela batusa imithi ukukhansela futhi esikhundleni Analogue salo, esiwulwazi iphephe kuwo impilo.