"Metronidazole" kuyiphi (amaphilisi)? Ukwelashwa "metronidazole": Izibuyekezo

Cabanga izidakamizwa "metronidazole". Ngokwalokho okushiwo odokotela linqume amaphilisi ezigulini zazo? Impendulo yalo mbuzo kungatholakala izinto sihloko. Uyofunda mayelana nokuthi iziphi izinhlelo kusenabantu izinhlobo ukukhululwa kwaleli thuluzi, njengoba kufanele kube.

ulwazi olujwayelekile mayelana ejenti kwemithi

I nomuthi "metronidazole", intengo zazo siyahlukahluka uhla 8-10 ruble Russian amaphilisi 20, kuyindlela ephumelela elwa namagciwane kanye antiprotozoal zokwenziwa izidakamizwa. Kumele kuqashelwe ukuthi le kuyindlela eshibhe eqenjini labo.

Khipha ifomu kanye nokwakheka izidakamizwa

Uyini izidakamizwa "metronidazole"? Kusukela lokho namaphilisi udokotela? Yiziphi imiphumela emibi engase abangele? Kuzo zonke lezi zinkinga siyosabela maduze. Ubani ofuna ukuxoxa ngayo lokho amafomu nezinye kwaleli thuluzi itholakale ukudayiselwa:

• isixazululo 0.5% ngoba ukumnika. Izindlela ezinjalo uketshezi ogqamile okusobala. 1 ml izidakamizwa equkethwe mayelana 5 mg isithako esisebenzayo - metronidazole. A isixazululo ukumnika is ithunyelwa amabhodlela 100 ml, okuyinto tihlelwe ebhokisini amakhadibhodi.
• Tablets. Enye yezindlela 'metronidazole "sibhebhe sinamaphutha 0.25 g we ketshezi main. Umuthi itholakale ukudayiselwa engu-10, 20 no-50 izingcezu.
• suppositories kwesitho sangasese. Omunye suppository iqukethe 0.5, 0.25 futhi 0,125 g lomcebo asebenzayo. Suppositories akhiqizwa izicucu eziyishumi, ngaphatha ibhokisi elinezincwadi kukhona torpedo emise nomhlophe (kungaba tinge aphuzi).
• 1% ijeli ye kungekho nto enemibala emihle lwesitho sangasese sowesifazane. 100 g ithuluzi iqukethe 1 g lomcebo asebenzayo. Lenza edayiswa amashubhu aluminium 30 g Le kit kuhlanganisa i nokokuyifaka.

pharmacodynamics

izidakamizwa "metronidazole" Isebenza kanjani? Tablets, okuyinto Izibuyekezo zahlukahlukene kakhulu, ezingeni kwamakhemikhali ukubuyisela 5-nitro iqembu usebenzisa amaprotheni ezokuthutha intracellular ka anaerobic nezilwanyana ezincane lenyama. Ngenxa umthelela wonke amagciwane aqala ukuba afe.

Kwezinye izimo, ngisho ikhombisa izidakamizwa "metronidazole"? Kusukela lokho namaphilisi iziguli izilonda duodenal nasesiswini? Njengoba ayaziwa lihambisana i "Amoxicillin" antibiotic nomuthi asebenzayo iyasebenza ngokumelene silwanyana ezinjalo kuba Helicobacter pylori.

Kufanele kuqashelwe ukuthi i-drug resistant ezinye anaerobes facultative nezinto ezincane eziphilayo aerobic. Nokho, ukuba khona okuxubile flora nomuthi "metronidazole" iqala ukwenza synergistically ndawonye zonke ngemithi elwa namagciwane ukuthi ziyasebenza ngokumelene aerobes.

Ngaphezu kwalokho, izidakamizwa ezinjalo kungandisa ukuzwela izimila emisebeni, kanye disulfiramopodobnyh umphumela futhi ashukumise ukulungisa izinqubo.

Izidakamizwa "metronidazole": yini amaphilisi?

imithi Okubukwe kuboniswe ngoba lezi zinkinga ezilandelayo:

• izifo Protozoal (isib Trichomonas lezinkinobho, emathunjini bese amebiasis extraintestinal, balantidiasis, trichomoniasis, giardiasis, Trichomonas urethritis futhi leishmaniasis cutaneous).
• Izifo ngisho namalungu, amathambo kanye isimiso sezinzwa esiyinhloko (isib, iphaphu ithumba, ubuchopho, meningitis, inyumoniya, endocarditis webhaktheriya , kanye empyema).
• izifo besisu (isib ithumba hepatic nokunye.), izifo kwezitho zangasese (endomyometritis, endometritis, ithumba wesibeletho kanye amashubhu fallopian), esithweni sangasese somuntu wesifazane ngemva kokuhlinzwa, izicubu zomzimba ezithambile nesikhumba.
• Kolwelwesi noma duodenal isilonda (esiswini), ehambisana ne-Helicobacter pylori.
• Sepsis, okuyinto kubangelwa Bacteroides SPP.
• nesifo Pseudomembranous, sihlobene ngokuqondile namaphuzu nokusetshenziswa kwamaphilisi.
• Ukuphuza ngokweqile.
• Njengoba umuthi radiosensitizing phakathi ukwelashwa ngemisebe.
• Ukuze avimbele izifo nasezinkingeni ezilandela ngemva kokuhlinzwa.

Izimo ukusetshenziswa kwezimali

Kwezinye izimo, awukwazi ukusebenzisa izidakamizwa "metronidazole"? Tablets (izibuyekezo ngazo Kamuva sizoxoxa ngokuthi), suppositories, isixazululo ukumnika, futhi ijeli is hhayi Kunconywa uma:

• leukopenia (kufaka phakathi umlando);
• izilonda organic we CNS;
• isithuthwane;
• ukuhluleka hepatic (ikakhulukazi ebulilini);
• Ezinyangeni zokuqala ezintathu zokukhulelwa;
• lactation;
• hypersensitivity.

Nomuthi "metronidazole": ukusetshenziswa amaphilisi

Leli thuluzi Kunconywa ukuthatha kuphela emva kokudla. Umthamo kanye nesikhathi yokwelapha kuncike ohlotsheni yezifo nokuguga lesiguli.

amaphilisi Trichomoniasis "metronidazole" ukuthatha kabili ngosuku izingcezu ezimbili izinsuku eziyishumi. Kufanele kuphawulwe ukuthi ngesikhathi sokwelashwa, kuyatuseka ukusebenzisa, futhi suppositories lwesitho sangasese sowesifazane. Suppositories iphathwa kabili ngosuku izingcezu ezimbili (ekuseni nakusihlwa). Ukwelashwa amakhandlela kufanele kwenziwe ekuqaleni umjikelezo wokuya esikhathini. Inkambo yokwelashwa kungaba liphindwe emva kwezinsuku ezingamashumi amathathu. Izingane izidakamizwa ekhethwe kule ngemithamo ezilandelayo: phezu iminyaka eyishumi nanye - 500 mg ngosuku, eminyakeni 5-11 - kuze kufinyelele 375 mg, eminyakeni 2-5 - 250 mg.

Phezu ukuthola izinhlumba izidakamizwa yaphathwa imali izibhebhe ezimbili kathathu ngosuku. Isikhathi ukwelashwa kungase isukela ezinhlanu kuya kweziyisishiyagalombili izinsuku.

Ukwelashwa "metronidazole" giardiasis kumele kwenziwe zingakapheli izinsuku 5-8 (amaphilisi amabili amabili ngosuku).

Ngo ezingamahlalakhona amebiasis izidakamizwa ukhombe 1.5 g umthamo watusa yahlukaniswa ngezigaba ezintathu. Ubude besikhathi sokwelashwa kwaba izinsuku 5-11.

Lapho amoebic uhudo (acute) nomuthi okufanele zithathwe ngokuvumelana 2.25g ngosuku kuze izimpawu kwakhawuka. I Isikali kumele ihlukaniswe izigaba ezintathu.

Lapho balantidiasis kusho "metronidazole" ezinqunyiwe 750 mg kathathu ngosuku izinsuku 5-8.

Lihambisana ejenti-antibiotic iqembu tetracycline nezinye izindlela zokwelapha ngaphansi ithumba isibindi yaphathwa inani esiphezulu 2.5 g izinsuku 3-5.

Ngo stomatitis esidalwa yizilonda emathunjini sibe Kunconywa ukuthatha izibhebhe ezimbili izidakamizwa kabili ngosuku (amalanga amahlanu). Ukuze ekwelapheni ukuluthwa utshwala kufanele baphuze amaphilisi amabili ngosuku izinyanga eziyisithupha.

Uma isiguli uzwakalise umsebenzi ukwephula izinso, umthamo wansuku zonke kumele kuyehla ngesigamu. Ngo ngamagciwane okunzima, futhi uma ungakwazi ukuthatha izindlela "metronidazole" ngaphakathi, it is ebekiwe ngemithambo yegazi. Ngalesi Isikali akufanele idlule 4 amagremu ngosuku. Nakuba ekuthuthukiseni ngezimo zesiguli kufanele ushintshele ku imithi ngomlomo.

side effects

iziguli eziningi zikholelwa ukuthi lokhu izidakamizwa kuyinto-antibiotic ezivamile. "Metronidazole" akayona i-ejenti antibiotic. Lena kuphela zokwenziwa izidakamizwa spectrum antiprotozoal futhi elwa namagciwane ebanzi umsebenzi. Kodwa leli qiniso ngabantu abaningi akuwenzi ube ephephile. Ngokusho kweziqondiso ezivela izidakamizwa ezifana has omningi engemihle. Phakathi kwabo kukhona lokhu okulandelayo:

• Uhudo, ezomile umlomo, sokuzincisha ukudla, ukuhlanza, ukuqunjelwa, ukucanuzela kwenhliziyo, glossitis, ukunambitheka metallic emlonyeni, pancreatitis.
• Cystitis, incontinence urinary, candidiasis, polyuria, dysuria, umchamo staining ngombala sinombala-bomvu.
• Isiyezi, ukuhhema, ukudideka, ukucindezeleka, ukucasuka, ukukhathazeka, futhi elihlaba abampofu ukunyakaza.
• Isifuba, ukuqubuka kwesikhumba, imfiva, ububomvu kwesikhumba, arthralgia, ukuminyana acinene.
• Neutropenia futhi leukopenia.

Uphenyo nomuthi

Izidakamizwa "metronidazole" (amaphilisi), ukusetshenziswa esesiye sacabangela kulesi sihloko has a lot of kokubili Izibuyekezo emihle nemibi. Labo ezigulini eziye ngokuphindaphindiwe wasebenzisa leli khambi for ekwelapheni isifo yimuphi, uthi ukusebenza kahle yayo okusezingeni eliphezulu. Nokho, abaningi kubo ngempela ngokuvamile akhononde ukuthi izidakamizwa inemiphumela eminingi engemihle, eziningi zazo kakade sobala ngosuku ukwelashwa wesibili noma wesithathu. Luqala ngokunikela i ezingemnandi ukunambitheka emlonyeni wakho. Ngaphezu kwalokho, kungase kube zekhanda ezinamandla, isiyezi, ukungakhululeki lapho esiswini engenhla, nokunye.

Lapho uzwakalise izigameko ezingezinhle ezavela, odokotela batusa ukuba ayeke ukuthatha imithi futhi esikhundleni salo ithuluzi efanayo.

Good ukwazi

Phakathi ukusetshenziswa nomuthi kubhekwe kumelwe siqaphele ikakhulukazi nesicelo ngesikhathi esisodwa amanye amalungiselelo. Lokhu kungenxa yokuthi isiguli ingase ibonise engadingeki side effects. Kufanele kuphawulwe ukuthi ngesikhathi imithi yokwelapha "metronidazole" is hhayi Kunconywa ukuba uphuze utshwala ngenxa ukuthuthukiswa okungenzeka izimpawu zokungasebenzi kahle kwemizwa.