Kusho ukuthini "Ranitidine" ukuthatha? Ukwelashwa nokuvikelwa isilungulela izilonda esiswini ngosizo "Ranitidine"

Luthini olwakho "Ranitidine" udokotela? Ngaphambi kokuba siphendule lo mbuzo, kubalulekile ukuthola ukuthi yini le izidakamizwa, yini isakhiwo it has, indlela okufanele zithathwe futhi kulokho ngemithamo?

Uhlolojikelele

Kusho ukuthini "Ranitidine" ingase ikhishwe? zokwenziwa izidakamizwa ezinjalo kuyinto izidakamizwa anti-isilonda, ezingasetshenziswa kakhulu inciphise juice esiswini.

Ukwakheka izidakamizwa futhi injalo ukukhululwa

Ukulungiselela "ranitidine" ikhiqizwa ukwakhiwa ezilandelayo:

• Tablets eziqukethe mg 300 futhi 0.15 g isithako esisebenzayo (ngesimo ranitidine hydrochloride). Lesi sidakamizwa itholakale ukudayiselwa at 100, 30 noma 20 izingcezu ibhokisi ngalinye.
• Isixazululo for umjovo. Lesi sidakamizwa isetshenziswa kuphela uma abaphathi ngomlomo izidakamizwa nganoma yisiphi isizathu engenakwenzeka. Isixazululo izidakamizwa okuthengiswa izitsha eziyisikhombisa 2 ml.

pharmacodynamics

Kusho ukuthini "Ranitidine" kaningi ebekwe odokotela? a Amalungiselelo anjalo, noma kunalokho ingxenye yayo iyasebenza, ngokushesha kunciphisa umthamo of juice esiswini, okuyinto kubangelwa esisuka Ukukhetha isitho main wokugaya ukudla. Njengomthetho, isimo sokugembula enjalo kungenxa umthwalo ngokweqile ukudla, kanye bedle ezinye stimulators biogenic (histamine, acetylcholine, gastrin, pentagastrin, ne-caffeine) kanye ama-hormone.

Ngemuva kwesicelo ekulungisweni "Ranitidine" nesineke Ukuvikelwa sithuthukiswe main isitho wokugaya ukudla mucosa, kanye nenani hydrochloric acid in juice yayo abahlukene encishisiwe. Kufanele kuqashelwe ukuthi uma usebenzisa lokhu izidakamizwa ukukhiqizwa injalo ingashintshile ka isikhwehlela futhi kungukuthi ukuyiveza enzymatic isibindi umsebenzi.

Nomuthi "Ranitidine" ikhuthaza ukuphulukiswa nokuvulwa zonke umonakalo we mucosa esiswini, okuyizinto ezihlobene ukuchayeka hydrochloric acid. Lo mphumela kungenxa nesanda izidakamizwa esiswini isikhwehlela kumiswa. Ngokusho imiyalelo, le nomuthi "Ranitidine" at umthamo we 0,15 g suppresses le uketshezi juice wokugaya ukudla umzimba omkhulu amahora 8-13.

Kusho ukuthini "Ranitidine" wona?

nomuthi okunjalo isetshenziselwa lokuchezuka ezilandelayo:

• isilonda 12 isilonda duodenal nasesiswini (ikakhulukazi esigabeni acute);
• ukuvuvukala emphinjeni, okuyinto ebangele ngokuphonsa kuyo okuqukethwe esiswini (e Reflux esophagitis);
• oesophagitis ngenxa yokwephulwa ubuqotho mucosa yayo (i esophagitis erosive) ;
• ngoba isilonda lingaze futhi ekhula 12 duodenum nasesiswini, eziwumphumela wokucindezeleka, ukuthatha imithi ethile noma ezinye izifo zangaphakathi;
• isisu izilonda lihambisana isimila ingozi kwamanyikwe (lapho Zollinger-Ellison syndrome).

Isicelo zokuvimbela

Ukulungiselela "Ranitidine" isisu ukuthatha, hhayi kuphela ngoba impatho kodwa nezalo ekugwemeni kwezinso ezilandelayo:

• exacerbations nezifo erosive ulcerous;
• izilonda izingxenye engenhla ipheshana wokugaya ukudla;
• juice esiswini angangeni ipheshana zokuphefumula phakathi nokuhlinza (i izinzwa).

Izimo

Tablets kusukela esiswini "Ranitidine" Kumele kuthathwe kuphela ngemva kokukhuluma nodokotela. Ngemva izidakamizwa anezinye Izimo:

• ukhulelwe;
• ezinganeni (ngaphansi 14 iminyaka);
• Hypersensitivity ukuthola usizo lwezempilo;
• lactation.

Futhi, lesi sidakamizwa "Ranitidine" iqondiswa ngokucophelela okukhulu ayephuli excretory izinso umsebenzi.

Isikali nezindlela kwesicelo

Kwethulwa ngu izidakamizwa yaphathwa imithamo obuhlukahlukene kuye uphethwe:

• Phakathi exacerbation izilonda 12 duodenum noma isisu nomuthi engabelwe ithebhulethi yokuqala kabili ngosuku noma 0.3 g ngobusuku obubodwa. Ngo-acute kunesidingo Isikali yansuku zonke ejenti kungase kukhule ku 400-450 mg.
• Nokuvinjelwa izilonda 12 isilonda duodenal noma izidakamizwa esiswini ebekwe 0.15g ngaphambi nje kokuba balale (kanye ngosuku).
• Lapho Zollinger-Ellison ithuluzi ku umthamo kokuqala iqondiswa i inani 1 ithebhulethi kathathu ngosuku. Lapho esiphuthumayo kuye kudingeke ukuba banikeze kungenzeka isibalo senyukela 0.7-0.9 g ngelanga.
• Esimeni izilonda ngemuva kokuhlinzwa ukulungiselela "Ranitidine" Kunconywa ukuthatha 0.15 g kabili ngosuku. Ngokuvamile, behluleka ukumphulukisa phezu amaviki 4.
• Ngokuba nokuvimbela ukucindezeleka izilonda izidakamizwa ebekiwe amaphilisi 2 kabili ngosuku.
• Tablets "Ranitidine" isilungulela belulekwa ukuba bangenise inani izingcezu yokuqala kabili ngosuku.

Ukuvimbela ukucindezeleka ulceration ukopha, kusho "Ranitidine" kumele kusetshenziswe intramuscularly noma ngemithambo yegazi noma 0.05 ukuze 0.1 g njalo emahoreni 7-8.

side effects

Lesi sidakamizwa kungabangela imiphumela elandelayo uhlangothi:

• ukuqubuka kwesikhumba;
• isiyezi;
• thrombocytopenia;
• ikhanda;
• ukukhathala.

Ezimweni ezingavamile, "Ranitidine" icuphe imithi nezinwele. Futhi kuboniswe ukuthi lo muthi kungaholela ukusangana futhi ephazamisekile emqondweni ukuthuthukisa. ekuphathweni Okungalapheki ebulilini isiguli kwandisa prolactin, gynecomastia kwenzeka, leukopenia, ubuthakathaka, amenorrhea futhi kwehle libido. Ngezinye izikhathi ukusetshenziswa kwezidakamizwa ezinjalo zingaholela ekuphathekeni ukuthuthukiswa zokusha kwesibindi.

Izixwayiso

• Lesi sidakamizwa iqondiswa ngokuqapha iziguli isibindi noma umsebenzi izinso ezinzima.
• Ngaphambi kokuba uqale ukwelashwa nge leli thuluzi, kufanele kwenzeke ukuba ngakususi khona esibulalayo isisu, emphinjeni noma duodenum 12.
• Uma imithi eziphuthumayo ukuqedwa kugingqika elokhu enciphisa umthamo.
• Ukuphumelela ukusetshenziswa prophylactic izifundo izidakamizwa ezingu-50 esikhathini ekwindla-entwasahlobo ka iphakeme kakhulu kunanoma uma njalo ethola.

analogue kwezimali

Analogue of nomuthi isenzo izidakamizwa "Zantac", "Rantak", "Ranisan", "Atsilok", "Ulran", "Ulkodin", "Ranigast" futhi "Ranitidine-akos". Kusho ukuthini konke lezi zimpahla zamukelwa? Ziqukethe isithako efanayo esebenzayo, ngakhoke ukufundwa amalungiselelo anjalo ayafana yini.